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Comparisons of Metabolic Measures to Predict T1D vs Detect a Preventive Treatment Effect in High-Risk Individuals.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 8, p. 2116, doi. 10.1210/clinem/dgae048
- By:
- Publication type:
- Article
Early Metabolic Endpoints Identify Persistent Treatment Efficacy in Recent-Onset Type 1 Diabetes Immunotherapy Trials.
- Published in:
- Diabetes Care, 2024, v. 47, n. 6, p. 1048, doi. 10.2337/dc24-0171
- By:
- Publication type:
- Article
High proinsulin:C-peptide ratio identifies individuals with stage 2 type 1 diabetes at high risk for progression to clinical diagnosis and responses to teplizumab treatment.
- Published in:
- Diabetologia, 2023, v. 66, n. 12, p. 2283, doi. 10.1007/s00125-023-06003-5
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- Publication type:
- Article
Screening and Prevention of Type 1 Diabetes: Where Are We?
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 12, p. 3067, doi. 10.1210/clinem/dgad328
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- Publication type:
- Article
A proteomic meta-analysis refinement of plasma extracellular vesicles.
- Published in:
- Scientific Data, 2023, v. 10, n. 1, p. 1, doi. 10.1038/s41597-023-02748-1
- By:
- Publication type:
- Article
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
- Published in:
- Diabetes, 2023, v. 72, n. 6, p. 746, doi. 10.2337/db22-0939
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- Publication type:
- Article
Phenotypes Associated With Zones Defined by Area Under the Curve Glucose and C-peptide in a Population With Islet Autoantibodies.
- Published in:
- Diabetes Care, 2023, v. 46, n. 5, p. 1098, doi. 10.2337/dc22-2236
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- Publication type:
- Article
Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial.
- Published in:
- JAMA: Journal of the American Medical Association, 2023, v. 329, n. 12, p. 980, doi. 10.1001/jama.2023.2063
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- Publication type:
- Article
Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial.
- Published in:
- JAMA: Journal of the American Medical Association, 2023, v. 329, n. 12, p. 990, doi. 10.1001/jama.2023.2064
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- Publication type:
- Article
Barriers to Screening: An Analysis of Factors Impacting Screening for Type 1 Diabetes Prevention Trials.
- Published in:
- Journal of the Endocrine Society, 2023, v. 7, n. 3, p. 1, doi. 10.1210/jendso/bvad003
- By:
- Publication type:
- Article
Persistence of β-Cell Responsiveness for Over Two Years in Autoantibody-Positive Children With Marked Metabolic Impairment at Screening.
- Published in:
- Diabetes Care, 2022, v. 45, n. 12, p. 2982, doi. 10.2337/dc22-1362
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- Publication type:
- Article
Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Index60 Identifies Individuals at Appreciable Risk for Stage 3 Among an Autoantibody-Positive Population With Normal 2-Hour Glucose Levels: Implications for Current Staging Criteria of Type 1 Diabetes.
- Published in:
- 2022
- By:
- Publication type:
- journal article
The Deterrence of Rapid Metabolic Decline Within 3 Months After Teplizumab Treatment in Individuals at High Risk for Type 1 Diabetes.
- Published in:
- 2021
- By:
- Publication type:
- journal article
1164-P: A Zebrafish Nonalcoholic Fatty Liver Disease Model Links Liver Inflammation with Pancreatic Inflammation and Hyperglycemia.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1164-P
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- Publication type:
- Article
589-P: Effect of Oral Insulin (OI) on Combined Glucose and C-Peptide Endpoints in Individuals at High-Risk for Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-589-P
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- Publication type:
- Article
75-OR: Marked Heterogeneity in Nondiabetic, Autoantibody-Positive (Ab+) Individuals with Dysglycemia: Implications for Type 1 Diabetes (T1D) Staging.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-75-OR
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- Publication type:
- Article
12-OR: Metabolic Effects of Two Oral Insulin Dosing Regimens in Individuals at High Risk for Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-12-OR
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- Publication type:
- Article
11-OR: Assessments of Prediagnostic Metabolic Measures as Surrogate Endpoints for Type 1 Diabetes (T1D) Prevention Trials.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-11-OR
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- Publication type:
- Article
Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
- Published in:
- Diabetes, 2021, v. 70, n. 5, p. 1038, doi. 10.2337/dbi20-0034
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- Publication type:
- Article
Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 583, p. 1, doi. 10.1126/scitranslmed.abc8980
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- Publication type:
- Article
Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes.
- Published in:
- Clinical Epigenetics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13148-020-00906-5
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- Publication type:
- Article
348-OR: Metabolic Phenotype of Autoantibody Positive (AbPos) Long-Term Nonprogressors (LTNPs) to Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-348-OR
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- Publication type:
- Article
80-OR: ß-Cell Hif1a-miR-21 Signaling Exacerbates ß-Cell Dysfunction Occurring during Diabetogenic Stress.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-80-OR
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- Publication type:
- Article
1618-P: Insulin Secretion Variability According to the Specific Type 1 Diabetes (T1D) Risk Predictor.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1618-P
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- Publication type:
- Article
1616-P: Stimulated ß-Cell Response Is Unaltered in Adult Autoantibody (AB) Negative Relatives of Individuals with Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1616-P
- By:
- Publication type:
- Article
276-OR: A 2-Dimensional (2D) Analysis of Glucose and C-Peptide Shows a Teplizumab Effect in Individuals at Risk for Type 1 Diabetes (T1D) 3 Months after Treatment.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-276-OR
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- Publication type:
- Article
277-OR: Teplizumab Reverses the Loss of C-Peptide in Relatives at Risk for Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-277-OR
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- Publication type:
- Article
1283-P: Multicenter Assessment of the Pancreas in Type 1 Diabetes (MAP-T1D).
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1283-P
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- Publication type:
- Article
Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet’s Pathway to Prevention.
- Published in:
- Diabetes Care, 2019, v. 42, n. 12, p. 2228, doi. 10.2337/dc19-0593
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- Publication type:
- Article
230-LB: Intraindividual Variability of Measures of Beta-Cell Response.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-230-LB
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- Publication type:
- Article
1684-P: Using Index60 to Detect Heterogeneity and Identify Subpopulations with Characteristic Type 1 Diabetes (T1D) Profiles among Individuals with Normal Two-Hour Glucose Levels.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1684-P
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- Publication type:
- Article
84-OR: Index60 and 2-Hour Glucose Diagnostic Thresholds: Comparison of Type 1 Diabetes (T1D) Marker Profiles.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-84-OR
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- Publication type:
- Article
1344-P: Persistent ß-Cell Responsiveness in Children at High Risk for Type 1 Diabetes (T1D) Is Associated with Decreased Progression to T1D in the Diabetes Prevention Trial-Type 1 (DPT-1).
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1344-P
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- Publication type:
- Article
Associations of HbA1c with the timing of C‐peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes.
- Published in:
- Pediatric Diabetes, 2019, v. 20, n. 4, p. 408, doi. 10.1111/pedi.12845
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- Publication type:
- Article
Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264.
- Published in:
- 2019
- By:
- Publication type:
- letter
Beta cells in type 1 diabetes: mass and function; sleeping or dead?
- Published in:
- Diabetologia, 2019, v. 62, n. 4, p. 567, doi. 10.1007/s00125-019-4822-4
- By:
- Publication type:
- Article
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes.
- Published in:
- PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0208456
- By:
- Publication type:
- Article
Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 1, p. 95, doi. 10.1111/dom.13489
- By:
- Publication type:
- Article
Biomarkers of islet beta cell stress and death in type 1 diabetes.
- Published in:
- Diabetologia, 2018, v. 61, n. 11, p. 2259, doi. 10.1007/s00125-018-4712-1
- By:
- Publication type:
- Article
Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function.
- Published in:
- PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197080
- By:
- Publication type:
- Article
Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes.
- Published in:
- Diabetologia, 2018, v. 61, n. 5, p. 1124, doi. 10.1007/s00125-018-4559-5
- By:
- Publication type:
- Article
Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Palmitate Induces mRNA Translation and Increases ER Protein Load in Islet β-Cells via Activation of the Mammalian Target of Rapamycin Pathway.
- Published in:
- Diabetes, 2014, v. 63, n. 10, p. 3404, doi. 10.2337/db14-0105
- By:
- Publication type:
- Article
Human Adipose-Derived Stromal/Stem Cells Protect Against STZ-Induced Hyperglycemia: Analysis of hASC-Derived Paracrine Effectors.
- Published in:
- Stem Cells, 2014, v. 32, n. 7, p. 1831, doi. 10.1002/stem.1676
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- Publication type:
- Article
Streptozotocin is equally diabetogenic whether administered to fed or fasted mice.
- Published in:
- Laboratory Animals, 2013, v. 47, n. 4, p. 257, doi. 10.1177/0023677213489548
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- Publication type:
- Article
Inhibin B and luteinizing hormone levels in girls aged 6-11 years from NHANES III, 1988-1994.
- Published in:
- Clinical Endocrinology, 2012, v. 77, n. 4, p. 555, doi. 10.1111/j.1365-2265.2012.04393.x
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- Publication type:
- Article
Detours on the Road to Diagnosis of Graves Disease.
- Published in:
- Clinical Pediatrics, 2012, v. 51, n. 2, p. 160, doi. 10.1177/0009922811418823
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- Publication type:
- Article
Contraception quandaries: oral contraceptive decisions in the pediatric endocrinology office.
- Published in:
- 2012
- By:
- Publication type:
- editorial