Works by Simons, Claire

Results: 40

Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data.

Published in:

2020

By:

Schlackow, Iryna;
Simons, Claire;
Oke, Jason;
Feakins, Benjamin;
O'Callaghan, Christopher A.;
Hobbs, F. D Richard;
Lasserson, Daniel;
Stevens, Richard J.;
Perera, Rafael;
Mihaylova, Borislava

Publication type:

journal article

HPLC enantiomeric resolution of novel aromatase inhibitors on cellulose- and amylose-based chiral stationary phases under reversed phase mode.

Published in:

Chirality, 2000, v. 12, n. 10, p. 727, doi. 10.1002/1520-636X(2000)12:10<727::AID-CHIR5>3.0.CO;2-T

By:

Aboul-Enein, Hassan Y.;
Ali, Imran;
Gübitz, Gerald;
Simons, Claire;
Nicholls, Paul J.

Publication type:

Article

Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues.

Published in:

BMC Chemistry, 2021, v. 15, n. 1, p. 1, doi. 10.1186/s13065-021-00785-8

By:

Noureldin, Nada A.;
Richards, Jennifer;
Kothayer, Hend;
Baraka, Mohammed M.;
Eladl, Sobhy M.;
Wootton, Mandy;
Simons, Claire

Publication type:

Article

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors.

Published in:

ChemistryOpen, 2019, v. 8, n. 7, p. 995, doi. 10.1002/open.201900227

By:

Kishk, Safaa M.;
McLean, Kirsty J.;
Sood, Sakshi;
Smith, Darren;
Evans, Jack W.D.;
Helal, Mohamed A.;
Gomaa, Mohamed S.;
Salama, Ismail;
Mostafa, Samia M.;
de Carvalho, Luiz Pedro S.;
Levy, Colin W.;
Munro, Andrew W.;
Simons, Claire

Publication type:

Article

Cost-effectiveness analysis of KTE-X19 CAR T therapy versus real-world standard of care in patients with relapsed/refractory mantle cell lymphoma post BTKi in England.

Published in:

Journal of Medical Economics, 2022, v. 25, n. 1, p. 730, doi. 10.1080/13696998.2022.2079317

By:

Petersohn, Svenja;
Salles, Gilles;
Wang, Michael;
Wu, Jim;
Wade, Sally W.;
Simons, Claire L.;
Bennison, Craig;
Siddiqi, Rubina;
Peng, Weimin;
Kloos, Ioana;
Castaigne, Gab;
Hess, Georg

Publication type:

Article

Cost-effectiveness for KTE-X19 CAR T therapy for adult patients with relapsed/refractory mantle cell lymphoma in the United States.

Published in:

Journal of Medical Economics, 2021, v. 24, p. 421, doi. 10.1080/13696998.2021.1894158

By:

Simons, Claire L.;
Malone, Daniel;
Wang, Michael;
Maglinte, Gregory A.;
Inocencio, Tim;
Wade, Sally W.;
Bennison, Craig;
Shah, Bijal

Publication type:

Article

Cost-effectiveness for KTE-X19 CAR T therapy for adult patients with relapsed/refractory mantle cell lymphoma in the United States.

Published in:

Journal of Medical Economics, 2021, v. 24, n. 1, p. 421, doi. 10.1080/13696998.2021.1894158

By:

Simons, Claire L.;
Malone, Daniel;
Wang, Michael;
Maglinte, Gregory A.;
Inocencio, Tim;
Wade, Sally W.;
Bennison, Craig;
Shah, Bijal

Publication type:

Article

Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis.

Published in:

Brain Structure & Function, 2016, v. 221, n. 6, p. 3315, doi. 10.1007/s00429-015-1102-z

By:

Stoney, Patrick;
Fragoso, Yara;
Saeed, Reem;
Ashton, Anna;
Goodman, Timothy;
Simons, Claire;
Gomaa, Mohamed;
Sementilli, Angelo;
Sementilli, Leonardo;
Ross, Alexander;
Morgan, Peter;
McCaffery, Peter

Publication type:

Article

Long-Term Outcomes of Eladocagene Exuparvovec Compared with Standard of Care in Aromatic l-Amino Acid Decarboxylase (AADC) Deficiency: A Modelling Study.

Published in:

Advances in Therapy, 2023, v. 40, n. 12, p. 5399, doi. 10.1007/s12325-023-02689-6

By:

Simons, Claire L.;
Hwu, Wuh-Liang;
Zhang, Rongrong;
Simons, Martijn J. H. G.;
Bergkvist, Mats;
Bennison, Craig

Publication type:

Article

Correction to: An Innovative Approach to Modelling the Optimal Treatment Sequence for Patients with Relapsing–Remitting Multiple Sclerosis: Implementation, Validation, and Impact of the Decision-Making Approach.

Published in:

2022

By:

Piena, Marjanne A.;
Kroep, Sonja;
Simons, Claire;
Fenwick, Elisabeth;
Harty, Gerard T.;
Wong, Schiffon L.;
van Hout, Ben A.

Publication type:

Correction Notice

An Innovative Approach to Modelling the Optimal Treatment Sequence for Patients with Relapsing–Remitting Multiple Sclerosis: Implementation, Validation, and Impact of the Decision-Making Approach.

Published in:

Advances in Therapy, 2022, v. 39, n. 2, p. 892, doi. 10.1007/s12325-021-01975-5

By:

Piena, Marjanne A.;
Kroep, Sonja;
Simons, Claire;
Fenwick, Elisabeth;
Harty, Gerard T.;
Wong, Schiffon L.;
van Hout, Ben A.

Publication type:

Article

Insights into Functional Dimerization of CYP121A1 of Mycobacterium tuberculosis.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04131

By:

Kumar, Amit;
Campomizzi, Christopher;
Jay, Natalie;
Ferguson, Shaun;
Scheffler, Emelie‐Jo;
Lioi, James;
Tu, Chengjian;
Qu, Jun;
Simons, Claire;
Estrada, David

Publication type:

Article

Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 9, p. 1263, doi. 10.3390/ph16091263

By:

Elbaramawi, Samar S.;
Eissa, Ahmed G.;
Noureldin, Nada A.;
Simons, Claire

Publication type:

Article

Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 8, p. 186, doi. 10.3390/ph13080186

By:

Lebouvier, Nicolas;
Pagniez, Fabrice;
Na, Young Min;
Shi, Da;
Pinson, Patricia;
Marchivie, Mathieu;
Guillon, Jean;
Hakki, Tarek;
Bernhardt, Rita;
Yee, Sook Wah;
Simons, Claire;
Lézé, Marie-Pierre;
Hartmann, Rolf W.;
Mularoni, Angélique;
Le Baut, Guillaume;
Krimm, Isabelle;
Abagyan, Ruben;
Le Pape, Patrice;
Le Borgne, Marc

Publication type:

Article

Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations.

Published in:

Journal of Molecular Modeling, 2012, v. 18, n. 2, p. 441, doi. 10.1007/s00894-011-1084-6

By:

Siam, Afraa;
Brancale, Andrea;
Simons, Claire

Publication type:

Article

A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions.

Published in:

Journal of Molecular Modeling, 2011, v. 17, n. 7, p. 1679, doi. 10.1007/s00894-010-0871-9

By:

Al-Moubarak, Ehab;
Simons, Claire

Publication type:

Article

Synthesis of Novel 6-Azapyrimidine Acyclic Nucleoside Analogues and Antiviral Evaluation.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2010, v. 29, n. 7, p. 535, doi. 10.1080/15257771003781634

By:

Jasamai, Malina;
Simons, Claire;
Balzarini, Jan

Publication type:

Article

Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1,2,3-triazole-4-yl derivatives as topoisomerase II inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 502, doi. 10.1080/14756366.2021.2021898

By:

Abdel-Hafez, Gehan A.;
Mohamed, Abdel-Maaboud I.;
Youssef, Adel F.;
Simons, Claire;
Aboraia, Ahmed S.

Publication type:

Article

Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl- N -benzylpropan-1-amine derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1694, doi. 10.3109/14756366.2016.1140754

By:

Eissa, Ahmed G.;
Blaxland, James A.;
Williams, Rhodri O.;
Metwally, Kamel A.;
El-Adl, Sobhy M.;
Lashine, El-Sayed M.;
Baillie, Leslie W. J.;
Simons, Claire

Publication type:

Article

SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDIN-2-ONE NUCLEOSIDES.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 731, doi. 10.1081/NCN-100002361

By:

Huntley, CarolineM.;
Cotterill, AnnS.;
Maillard, Jean-Yves;
Balzarini, Jan;
Simons, Claire

Publication type:

Article

METHYL 5-O-BENZOYL-2,3-OXAZOLE-D-RIBOFURANOSIDE: A USEFUL INTERMEDIATE FOR THE SYNTHESIS OF CONFORMATIONALLY RESTRAINED NUCLEOSIDES.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 981, doi. 10.1081/NCN-100002473

By:

Molina, José;
Maslen, HannahL.;
Simons, Claire

Publication type:

Article

Pitfalls and possibilities in literacy research: A review of South African literacy studies, 2004–2018.

Published in:

Reading & Writing (20798245), 2020, v. 11, n. 1, p. 1, doi. 10.4102/rw.v11i1.238

By:

Biesman-Simons, Claire;
Dixon, Kerryn;
Pretorius, Elizabeth;
Reed, Yvonne

Publication type:

Article

Targeting Mycobacterium tuberculosis: Synthesis, in vitro and in silico evaluation of novel N<sup>1</sup>‐(benzo[d]oxazol‐2‐yl)‐N<sup>4</sup>‐arylidine compounds.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 8, p. 1, doi. 10.1002/ardp.202300187

By:

Zawal, Amira G.;
Abdel‐Aziz, Marwa M.;
El‐Shanawani, Abdalla A.;
Abdel‐Aziz, Lobna M.;
Taha, Mohamed;
Simons, Claire;
Elbaramawi, Samar S.

Publication type:

Article

Design and synthesis of substituted imidazole and triazole N-phenylbenzo[d]oxazolamine inhibitors of retinoic acid metabolizing enzyme CYP26.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 2, p. 487, doi. 10.1080/14756360802218334

By:

Pautus, Stephane;
Aboraia, Ahmed S.;
Bassett, Claire E.;
Brancale, Andrea;
Coogan, Michael P.;
Simons, Claire

Publication type:

Article

6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2008, v. 23, n. 1, p. 56, doi. 10.1080/14756360701442340

By:

Jasamai, Malina;
Balzarini, Jan;
Simons, Claire

Publication type:

Article

Homology Model of Human Retinoic Acid Metabolising Enzyme Cytochrome P450 26A1 (CYP26A1): Active Site Architecture and Ligand Binding.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2006, v. 21, n. 4, p. 361, doi. 10.1080/14756360600742014

By:

Gomaa, Mohamed Sayed;
Yee, Sook Wah;
Milbourne, Ceri Elizabeth;
Barbera, Maria Chiara;
Simons, Claire;
Brancale, Andrea

Publication type:

Article

Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3,4-dihydronaphthalen-1(2 H )-one on all- trans and 13- cis -retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2005, v. 20, n. 3, p. 219, doi. 10.1080/14756360400008889

By:

Angotti, Marc;
Hartmann, Rolf W.;
Kirby, Andrew J.;
Simons, Claire;
Nicholls, Paul J.;
Sewell, Robert D.E.;
John Smith, H.

Publication type:

Article

Synthesis and antimycobacterial activity of 7-O-substituted-4-methyl-2H-2-chromenone derivatives vsMycobacterium tuberculosis.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2005, v. 20, n. 2, p. 109, doi. 10.1080/14756360400002015

By:

Sook Wah Yee;
Binal Shah;
Simons, Claire

Publication type:

Article

Benzofuran- and furan-2-yl-(phenyl)-3-pyridylmethanols: Synthesis and inhibition of P450 aromatase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2005, v. 20, n. 2, p. 135, doi. 10.1080/14756360400015256

By:

Sabert, Mohammed R.;
Shah, Kajal;
Simons, Claire

Publication type:

Article

Some Aryl Substituted 2-(4-Nitrophenyl)-4-oxo-4-phenylbutanoates and 3-(4-Nitrophenyl)-1-phenyl-1,4-butanediols and Related Compounds as Inhibitors of Rat Liver Microsomal Retinoic Acid Metabolising Enzymes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2003, v. 18, n. 6, p. 511, doi. 10.1080/1475636032000141881

By:

Mason, Peter;
Greer, Valerie P.;
Kirby, Andrew J.;
Simons, Claire;
Nicholls, Paul J.;
Smith, H. John

Publication type:

Article

Inhibition of Retinoic Acid Metabolising Enzymes by 2-(4-aminophenylmethyl)-6-hydroxy-3,4- dihydronaphthalen-1(2H)-one and Related Compounds.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2003, v. 18, n. 1, p. 27, doi. 10.1080/1475636021000049221

By:

Kirby, Andrew J.;
Le Lain, Regis;
Maharlouie, Farshid;
Mason, Peter;
Nicholls, Paul J.;
Smith, H. John;
Simons, Claire

Publication type:

Article

Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells.

Published in:

Journal of Drug Targeting, 2020, v. 28, n. 6, p. 643, doi. 10.1080/1061186X.2019.1710157

By:

Bilip, Maja;
Shah, Shreya;
Mathiyalakan, Mayuran;
Tagalakis, Aristides D.;
Hart, Stephen L.;
Maeshima, Ruhina;
Eaton, Simon;
Orford, Michael;
Irving, Elsa;
Di Florio, Alessia;
Simons, Claire;
Stoker, Andrew W.

Publication type:

Article

Multiple imputation to deal with missing EQ-5D-3L data: Should we impute individual domains or the actual index?

Published in:

Quality of Life Research, 2015, v. 24, n. 4, p. 805, doi. 10.1007/s11136-014-0837-y

By:

Simons, Claire;
Rivero-Arias, Oliver;
Yu, Ly-Mee;
Simon, Judit

Publication type:

Article

Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79545-y

By:

Kumar, Amit;
Campomizzi, Christopher S.;
Jay, Natalie;
Ferguson, Shaun;
Scheffler, Emelie-Jo;
Lioi, James;
Tu, Chengjian;
Qu, Jun;
Simons, Claire;
Estrada, D. Fernando

Publication type:

Article

Synthesis of An Unusual Tetrahydrofuro[3,4- D ] Oxazole Ring System.

Published in:

Journal of Carbohydrate Chemistry, 2000, v. 19, n. 8, p. 991, doi. 10.1080/07328300008544130

By:

Molina, José;
Simons, Claire

Publication type:

Article

Convenient Synthesis of 2-Deoxy-D-Glucofuranosides.

Published in:

Journal of Carbohydrate Chemistry, 1999, v. 18, n. 5, p. 535, doi. 10.1080/07328309908544017

By:

Arévalo, José Molina;
Simons, Claire

Publication type:

Article

Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans.

Published in:

ChemMedChem, 2020, v. 15, n. 14, p. 1294, doi. 10.1002/cmdc.202000250

By:

Binjubair, Faizah A.;
Parker, Josie E.;
Warrilow, Andrew G.;
Puri, Kalika;
Braidley, Peter J.;
Tatar, Esra;
Kelly, Steven L.;
Kelly, Diane E.;
Simons, Claire

Publication type:

Article

Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5007, doi. 10.3390/molecules25215007

By:

Kishk, Safaa M.;
Kishk, Rania M.;
Yassen, Asmaa S. A.;
Nafie, Mohamed S.;
Nemr, Nader A.;
ElMasry, Gamal;
Al-Rejaie, Salim;
Simons, Claire

Publication type:

Article

Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 7, p. 1589, doi. 10.1093/jac/dks129

By:

Linley, Ezra;
Denyer, Stephen P.;
McDonnell, Gerald;
Simons, Claire;
Maillard, Jean-Yves

Publication type:

Article

Mode of action of hydrogen peroxide and other oxidizing agents: differences between liquid and gas forms.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. 10, p. 2108, doi. 10.1093/jac/dkq308

By:

Finnegan, Michelle;
Linley, Ezra;
Denyer, Stephen P.;
McDonnell, Gerald;
Simons, Claire;
Maillard, Jean-Yves

Publication type:

Article