Works by Simes, John

Results: 127
    1

    Imatinib alternating with regorafenib compared to imatinib alone for the first-line treatment of advanced gastrointestinal stromal tumor: The AGITG ALT-GIST intergroup randomized phase II trial.

    Published in:
    British Journal of Cancer, 2025, v. 132, n. 10, p. 897, doi. 10.1038/s41416-025-02983-w
    By:
    • Yip, Desmond;
    • Zalcberg, John;
    • Blay, Jean-Yves;
    • Eriksson, Mikael;
    • Espinoza, David;
    • Price, Timothy;
    • Marreaud, Sandrine;
    • Italiano, Antoine;
    • Steeghs, Neeltje;
    • Boye, Kjetil;
    • Underhill, Craig;
    • Gebski, Val;
    • Simes, John;
    • Gelderblom, Hans;
    • Joensuu, Heikki
    Publication type:
    Article
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    Imputation of plasma lipid species to facilitate integration of lipidomic datasets.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45838-3
    By:
    • Dakic, Aleksandar;
    • Wu, Jingqin;
    • Wang, Tingting;
    • Huynh, Kevin;
    • Mellett, Natalie;
    • Duong, Thy;
    • Beyene, Habtamu B.;
    • Magliano, Dianna J.;
    • Shaw, Jonathan E.;
    • Carrington, Melinda J.;
    • Inouye, Michael;
    • Yang, Jean Y.;
    • Figtree, Gemma A.;
    • Curran, Joanne E.;
    • Blangero, John;
    • Simes, John;
    • LIPID Study Investigators;
    • Giles, Corey;
    • Meikle, Peter J.
    Publication type:
    Article
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    Early circulating tumor DNA dynamics as a pan‐tumor biomarker for long‐term clinical outcome in patients treated with durvalumab and tremelimumab.

    Published in:
    Molecular Oncology, 2023, v. 17, n. 2, p. 298, doi. 10.1002/1878-0261.13349
    By:
    • Kansara, Maya;
    • Bhardwaj, Neeru;
    • Thavaneswaran, Subotheni;
    • Xu, Chang;
    • Lee, Jessica K.;
    • Chang, Lo‐Bin;
    • Madison, Russell W.;
    • Lin, Frank;
    • Hsu, Eugene;
    • Patel, Vipul Kumar;
    • Aleshin, Alexey;
    • Oxnard, Geoffrey R.;
    • Simes, John;
    • Nimeiri, Halla;
    • Thomas, David M.
    Publication type:
    Article
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    A signal-seeking Phase 2 study of olaparib and durvalumab in advanced solid cancers with homologous recombination repair gene alterations.

    Published in:
    British Journal of Cancer, 2023, v. 129, n. 3, p. 475, doi. 10.1038/s41416-023-02311-0
    By:
    • Thavaneswaran, Subotheni;
    • Kansara, Maya;
    • Lin, Frank;
    • Espinoza, David;
    • Grady, John P.;
    • Lee, Chee Khoon;
    • Ballinger, Mandy L.;
    • Sebastian, Lucille;
    • Corpuz, Theresa;
    • Qiu, Min Ru;
    • Mundra, Piyushkumar;
    • Bailey, Charles G.;
    • Schmitz, Ulf;
    • Simes, John;
    • Joshua, Anthony M.;
    • Thomas, David M.
    Publication type:
    Article
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    Cetuximab Alone or With Irinotecan for Resistant KRAS-, NRAS-, BRAF- and PIK3CA-wild-type Metastatic Colorectal Cancer: The AGITG Randomized Phase II ICECREAM Study.

    Published in:
    2018
    By:
    • Shapiro, Jeremy D.;
    • Thavaneswaran, Subotheni;
    • Underhill, Craig R.;
    • Robledo, Kristy P.;
    • Karapetis, Christos S.;
    • Day, Fiona L.;
    • Nott, Louise M.;
    • Jefford, Michael;
    • Chantrill, Lorraine A.;
    • Pavlakis, Nick;
    • Tebbutt, Niall C.;
    • Price, Timothy. J.;
    • Khasraw, Mustafa;
    • Van Hazel, Guy A.;
    • Waring, Paul M.;
    • Tejpar, Sabine;
    • Simes, John;
    • Gebski, Val J.;
    • Desai, Jayesh;
    • Segelov, Eva
    Publication type:
    journal article
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    Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project.

    Published in:
    2018
    By:
    • Sjoquist, Katrin M.;
    • Renfro, Lindsay A.;
    • Simes, R. John;
    • Tebbutt, Niall C.;
    • Clarke, Stephen;
    • Seymour, Matthew T.;
    • Adams, Richard;
    • Maughan, Timothy S.;
    • Saltz, Leonard;
    • Goldberg, Richard M.;
    • Schmoll, Hans-Joachim;
    • Van Cutsem, Eric;
    • Douillard, Jean-Yves;
    • Hoff, Paulo M.;
    • Hecht, Joel Randolph;
    • Tournigand, Christophe;
    • Punt, Cornelis J. A.;
    • Koopman, Miriam;
    • Hurwitz, Herbert;
    • Heinemann, Volker
    Publication type:
    journal article
    32

    Early Decline in Cancer Antigen 125 as a Surrogate for Progression-Free Survival in Recurrent Ovarian Cancer.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 17, p. 1338, doi. 10.1093/jnci/djr282
    By:
    • Lee, Chee K.;
    • Friedlander, Michael;
    • Brown, Chris;
    • Gebski, Val J.;
    • Georgoulopoulos, Alexander;
    • Vergote, Ignace;
    • Pignata, Sandro;
    • Donadello, Nicoletta;
    • Schmalfeldt, Barbara;
    • Delva, Rémy;
    • Mirza, Mansoor Raza;
    • Sauthier, Philippe;
    • Pujade-Lauraine, Eric;
    • Lord, Sarah J.;
    • Simes, R. John
    Publication type:
    Article
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    Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 17, p. 1182, doi. 10.1093/jnci/djp232
    By:
    • Mittmann, Nicole;
    • Au, Heather-Jane;
    • Tu, Dongsheng;
    • O'Callaghan, Christopher J.;
    • Isogai, Pierre K.;
    • Karapetis, Christos S.;
    • Zalcberg, John R.;
    • Evans, William K.;
    • Moore, Malcolm J.;
    • Siddiqui, Jehan;
    • Findlay, Brian;
    • Colwell, Bruce;
    • Simes, John;
    • Gibbs, Peter;
    • Links, Matthew;
    • Tebbutt, Niall C.;
    • Jonker, Derek J.
    Publication type:
    Article
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    RESPONSE.

    Published in:
    2006
    By:
    • Gebski, Val;
    • Lagleva, Marivic;
    • Keech, Anthony;
    • Simes, John;
    • Langlands, Allan
    Publication type:
    Letter
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    A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 10, p. 1736, doi. 10.1093/neuonc/noab111
    By:
    • Sim, Hao-Wen;
    • McDonald, Kerrie L;
    • Lwin, Zarnie;
    • Barnes, Elizabeth H;
    • Rosenthal, Mark;
    • Foote, Matthew C;
    • Koh, Eng-Siew;
    • Back, Michael;
    • Wheeler, Helen;
    • Sulman, Erik P;
    • Buckland, Michael E;
    • Fisher, Lauren;
    • Leonard, Robyn;
    • Hall, Merryn;
    • Ashley, David M;
    • Yip, Sonia;
    • Simes, John;
    • Khasraw, Mustafa
    Publication type:
    Article
    38

    Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.

    Published in:
    Neuro-Oncology, 2019, v. 21, n. 1, p. 106, doi. 10.1093/neuonc/noy091
    By:
    • Lassman, Andrew B;
    • Bent, Martin J van den;
    • Gan, Hui K;
    • Reardon, David A;
    • Kumthekar, Priya;
    • Butowski, Nicholas;
    • Lwin, Zarnie;
    • Mikkelsen, Tom;
    • Nabors, Louis B;
    • Papadopoulos, Kyriakos P;
    • Penas-Prado, Marta;
    • Simes, John;
    • Wheeler, Helen;
    • Walbert, Tobias;
    • Scott, Andrew M;
    • Gomez, Erica;
    • Lee, Ho-Jin;
    • Roberts-Rapp, Lisa;
    • Xiong, Hao;
    • Ansell, Peter J
    Publication type:
    Article
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    Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma.

    Published in:
    Neuro-Oncology, 2015, v. 17, n. 11, p. 1504, doi. 10.1093/neuonc/nov104
    By:
    • Field, Kathryn M.;
    • Simes, John;
    • Nowak, Anna K.;
    • Cher, Lawrence;
    • Wheeler, Helen;
    • Hovey, Elizabeth J.;
    • Brown, Christopher S. B.;
    • Barnes, Elizabeth H.;
    • Sawkins, Kate;
    • Livingstone, Ann;
    • Freilich, Ron;
    • Phal, Pramit M.;
    • Fitt, Greg;
    • Rosenthal, Mark A.
    Publication type:
    Article
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    Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials.

    Published in:
    European Heart Journal, 2005, v. 26, n. 2, p. 128, doi. 10.1093/eurheartj/ehi061
    By:
    • Labinaz, Marino;
    • Mathias, Jasmine;
    • Pieper, Karen;
    • Granger, Christopher B.;
    • Lincoff, A. Michael;
    • Moliterno, David J.;
    • Van de Werf, Frans;
    • Simes, John;
    • White, Harvey D.;
    • Simoons, Maarten L.;
    • Califf, Robert M.;
    • Topol, Eric J.;
    • Armstrong, Paul W.;
    • Harrington, Robert A.
    Publication type:
    Article
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    Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model.

    Published in:
    British Journal of General Practice, 2024, v. 74, n. 740, p. e189, doi. 10.3399/bjgp.2023.0198
    By:
    • Wu, Runguo;
    • Williams, Claire;
    • Zhou, Junwen;
    • Schlackow, Iryna;
    • Emberson, Jonathan;
    • Reith, Christina;
    • Keech, Anthony;
    • Robson, John;
    • Armitage, Jane;
    • Gray, Alastair;
    • Simes, John;
    • Baigent, Colin;
    • Mihaylova, Borislava;
    • Barnes, Elizabeth;
    • Blackwell, Lisa;
    • Collins, Rory;
    • Davies, Kelly;
    • Fulcher, Jordan;
    • Halls, Heather;
    • Herrington, William G
    Publication type:
    Article