Works by Simard, J Marc

Results: 91

Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis.

Published in:

2017

By:

Gerzanich, Volodymyr;
Min Seong Kwon;
Stokum, Jesse A.;
Seung Kyoon Woo;
Ivanova, Svetlana;
Ivanov, Alexander;
Simard, J. Marc;
Makar, Tapas K.;
Bever, Christopher T.;
Reddy Guda, Poornachander;
Brooke Morris, Alexandra;
Mehta, Rupal I.;
Bryan, Joseph;
Guda, Poornachander Reddy;
Kwon, Min Seong;
Woo, Seung Kyoon;
Morris, Alexandra Brooke;
Marc Simard, J

Publication type:

journal article

Understanding the Role of SARS-CoV-2 ORF3a in Viral Pathogenesis and COVID-19.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.854567

By:

Zhang, Jiantao;
Ejikemeuwa, Amara;
Gerzanich, Volodymyr;
Nasr, Mohamed;
Tang, Qiyi;
Simard, J. Marc;
Zhao, Richard Y.

Publication type:

Article

Adherens, tight, and gap junctions in ependymal cells: A systematic review of their contribution to CSF-brain barrier.

Published in:

Frontiers in Neurology, 2023, v. 14, p. 1, doi. 10.3389/fneur.2023.1092205

By:

Serra, Riccardo;
Simard, J. Marc

Publication type:

Article

Correction: Cerebral microbleeds in a neonatal rat model.

Published in:

2018

By:

Theriault, Brianna C.;
Woo, Seung Kyoon;
Karimy, Jason K.;
Keledjian, Kaspar;
Stokum, Jesse A.;
Sarkar, Amrita;
Coksaygan, Turhan;
Ivanova, Svetlana;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Correction Notice

SUR1-TRPM4 channel activation and phasic secretion of MMP-9 induced by tPA in brain endothelial cells.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0195526

By:

Gerzanich, Volodymyr;
Kwon, Min Seong;
Woo, Seung Kyoon;
Ivanov, Alexander;
Simard, J. Marc

Publication type:

Article

Emerging therapeutic targets for cerebral edema.

Published in:

Expert Opinion on Therapeutic Targets, 2021, v. 25, n. 11, p. 917, doi. 10.1080/14728222.2021.2010045

By:

Jha, Ruchira M.;
Raikwar, Sudhanshu P.;
Mihaljevic, Sandra;
Casabella, Amanda M.;
Catapano, Joshua S.;
Rani, Anupama;
Desai, Shashvat;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury.

Published in:

Nature Medicine, 2009, v. 15, n. 2, p. 185, doi. 10.1038/nm.1899

By:

Gerzanich, Volodymyr;
Woo, S Kyoon;
Vennekens, Rudi;
Tsymbalyuk, Orest;
Ivanova, Svetlana;
Ivanov, Alexander;
Geng, Zhihua;
Chen, Zheng;
Nilius, Bernd;
Flockerzi, Veit;
Freichel, Marc;
Simard, J Marc

Publication type:

Article

Newly expressed SUR1-regulated NCCa-ATP channel mediates cerebral edema after ischemic stroke.

Published in:

Nature Medicine, 2006, v. 12, n. 4, p. 433, doi. 10.1038/nm1390

By:

Simard, J. Marc;
Mingkui Chen;
Tarasov, Kirill V.;
Bhatta, Sergei;
Ivanova, Svetlana;
Melnitchenko, Ludmila;
Tsymbalyuk, Natalya;
West, G. Alexander;
Gerzanich, Volodymyr

Publication type:

Article

Target Ultra and Nano coils in the endovascular treatment of small intracranial aneurysms (ULTRA Registry).

Published in:

Journal of Neurosurgery, 2023, v. 138, n. 1, p. 233, doi. 10.3171/2022.5.JNS2296

By:

Jindal, Gaurav;
Almardawi, Ranyah;
Gupta, Rishi;
Colby, Geoffrey P.;
Schirmer, Clemens M.;
Satti, Sudhakar R.;
Pukenas, Bryan;
Hui, Ferdinand K.;
Caplan, Justin;
Miller, Timothy;
Cherian, Jacob;
Aldrich, Francois;
Kibria, Gulam;
Simard, J. Marc

Publication type:

Article

A sustained systemic inflammatory response syndrome is associated with shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage.

Published in:

Journal of Neurosurgery, 2019, v. 130, n. 6, p. 1986, doi. 10.3171/2018.1.JNS172925

By:

Wessell, Aaron P.;
Kole, Matthew J.;
Cannarsa, Gregory;
Oliver, Jeffrey;
Jindal, Gaurav;
Miller, Timothy;
Gandhi, Dheeraj;
Parikh, Gunjan;
Badjatia, Neeraj;
Aldrich, E. Francois;
Simard, J. Marc

Publication type:

Article

Continuous infusion of low-dose unfractionated heparin after aneurysmal subarachnoid hemorrhage: a preliminary study of cognitive outcomes.

Published in:

Journal of Neurosurgery, 2019, v. 130, n. 5, p. 1460, doi. 10.3171/2017.11.JNS17894

By:

James, Robert F.;
Khattar, Nicolas K.;
Aljuboori, Zaid S.;
Page, Paul S.;
Shao, Elaine Y.;
Carter, Lacey M.;
Meyer, Kimberly S.;
Daniels, Michael W.;
Craycroft, John;
Gaughen Jr., John R.;
Chaudry, M. Imran;
Rai, Shesh N.;
Everhart, D. Erik;
Simard, J. Marc

Publication type:

Article

Low-dose intravenous heparin infusion in patients with aneurysmal subarachnoid hemorrhage: a preliminary assessment.

Published in:

Journal of Neurosurgery, 2013, v. 119, n. 6, p. 1611, doi. 10.3171/2013.8.JNS1337

By:

SIMARD, J. MARC;
ALDRICH, E. FRANCOIS;
SCHREIBMAN, DAVID;
JAMES, ROBERT F.;
POLIFKA, ADAM;
BEATY, NARLIN

Publication type:

Article

Spetzler-Martin Grade III arteriovenous malformations: RESPONSE.

Published in:

Journal of Neurosurgery, 2013, v. 119, n. 3, p. 821, doi. 10.3171/2012.11.JNS122231

By:

SIMARD, J. MARC;
KOLTZ, MICHAEL T.;
POLIFKA, ADAM J.;
SALTOS, ANDREAS;
SLAWSON, ROBERT G.;
YOUNG KWOK;
ALDRICH, E. FRANCOIS

Publication type:

Article

Long-term outcome of Gamma Knife stereotactic radiosurgery for arteriovenous malformations graded by the Spetzler-Martin classification.

Published in:

Journal of Neurosurgery, 2013, v. 118, n. 1, p. 74, doi. 10.3171/2012.9.JNS112329

By:

KOLTZ, MICHAEL T.;
POLIFKA, ADAM J.;
SALTOS, ANDREAS;
SLAWSON, ROBERT G.;
KWOK, YOUNG;
ALDRICH, E. FRANCOIS;
SIMARD, J. MARC

Publication type:

Article

RiboTag RNA Sequencing Identifies Local Translation of HSP70 in Astrocyte Endfeet After Cerebral Ischemia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 309, doi. 10.3390/ijms26010309

By:

Shim, Bosung;
Ciryam, Prajwal;
Tosun, Cigdem;
Serra, Riccardo;
Tsymbalyuk, Natalya;
Keledjian, Kaspar;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Early pathophysiological changes in cerebral vessels predisposing to stroke.

Published in:

Clinical Hemorheology & Microcirculation, 2003, v. 29, n. 3-4, p. 291

By:

Volodymyr Gerzanich, Bob;
Svetlana Ivanova;
J. Marc Simard

Publication type:

Article

Author Correction: 7,8-Dihydroxyflavone improves neuropathological changes in the brain of Tg26 mice, a model for HIV-associated neurocognitive disorder.

Published in:

2021

By:

Bryant, Joseph;
Andhavarapu, Sanketh;
Bever, Christopher;
Guda, Poornachander;
Katuri, Akhil;
Gupta, Udit;
Arvas, Muhammed;
Asemu, Girma;
Heredia, Alonso;
Gerzanich, Volodymyr;
Simard, J. Marc;
Makar, Tapas Kumar

Publication type:

Correction Notice

7,8-Dihydroxyflavone improves neuropathological changes in the brain of Tg26 mice, a model for HIV-associated neurocognitive disorder.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97220-8

By:

Bryant, Joseph;
Andhavarapu, Sanketh;
Bever, Christopher;
Guda, Poornachander;
Katuri, Akhil;
Gupta, Udit;
Arvas, Muhammed;
Asemu, Girma;
Heredia, Alonso;
Gerzanich, Volodymyr;
Simard, Marc J.;
Makar, Tapas Kumar

Publication type:

Article

Brain Swelling versus Infarct Size: A Problematizing Review.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 3, p. 229, doi. 10.3390/brainsci14030229

By:

Simard, J. Marc;
Wilhelmy, Bradley;
Tsymbalyuk, Natalya;
Shim, Bosung;
Stokum, Jesse A.;
Evans, Madison;
Gaur, Anandita;
Tosun, Cigdem;
Keledjian, Kaspar;
Ciryam, Prajwal;
Serra, Riccardo;
Gerzanich, Volodymyr

Publication type:

Article

The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity.

Published in:

Brain Sciences (2076-3425), 2013, v. 3, n. 1, p. 215, doi. 10.3390/brainsci3010215

By:

Tosun, Cigdem;
Koltz, Michael T.;
Kurland, David B.;
Ijaz, Hina;
Gurakar, Melda;
Schwartzbauer, Gary;
Coksaygan, Turhan;
Ivanova, Svetlana;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Unruptured cerebral aneurysms in elderly patients: key challenges and management.

Published in:

Annals of Medicine, 2021, v. 53, n. 1, p. 1839, doi. 10.1080/07853890.2021.1990393

By:

Caffes, Nicholas;
Wenger, Nicole;
Cannarsa, Gregory;
Oliver, Jeffrey;
Onwukwe, Chimdiya;
Gandhi, Dheeraj;
Simard, J. Marc

Publication type:

Article

Unruptured cerebral aneurysms in elderly patients: key challenges and management.

Published in:

Annals of Medicine, 2021, v. 53, n. 1, p. 1839, doi. 10.1080/07853890.2021.1990393

By:

Caffes, Nicholas;
Wenger, Nicole;
Cannarsa, Gregory;
Oliver, Jeffrey;
Onwukwe, Chimdiya;
Gandhi, Dheeraj;
Simard, J. Marc

Publication type:

Article

Changes in Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy in a Direct Cranial Blast Traumatic Brain Injury (dc-bTBI) Model.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136151

By:

Zhuo, Jiachen;
Keledjian, Kaspar;
Xu, Su;
Pampori, Adam;
Gerzanich, Volodymyr;
Simard, J. Marc;
Gullapalli, Rao P.

Publication type:

Article

Craniectomy for Malignant Cerebral Infarction: Prevalence and Outcomes in US Hospitals.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029193

By:

Walcott, Brian P.;
Kuklina, Elena V.;
Nahed, Brian V.;
George, Mary G.;
Kahle, Kristopher T.;
Simard, J. Marc;
Asaad, Wael F.;
Coumans, Jean-Valery C. E.

Publication type:

Article

Functional Coupling between Sulfonylurea Receptor Type 1 and a Nonselective Cation Channel in Reactive Astrocytes from Adult Rat Brain.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 24, p. 8568, doi. 10.1523/JNEUROSCI.23-24-08568.2003

By:

Mingkui Chen;
Yafeng Dong;
Simard, J. Marc

Publication type:

Article

SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury.

Published in:

Molecular Pain, 2021, v. 17, p. 1, doi. 10.1177/17448069211006603

By:

Tsymbalyuk, Orest;
Gerzanich, Volodymyr;
Mumtaz, Aaida;
Andhavarapu, Sanketh;
Ivanova, Svetlana;
Makar, Tapas K;
Sansur, Charles A;
Keller, Asaf;
Nakamura, Yumiko;
Bryan, Joseph;
Simard, J Marc

Publication type:

Article

SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury.

Published in:

Molecular Pain, 2021, p. 1, doi. 10.1177/17448069211006603

By:

Tsymbalyuk, Orest;
Gerzanich, Volodymyr;
Mumtaz, Aaida;
Andhavarapu, Sanketh;
Ivanova, Svetlana;
Makar, Tapas K;
Sansur, Charles A;
Keller, Asaf;
Nakamura, Yumiko;
Bryan, Joseph;
Simard, J Marc

Publication type:

Article

HMGB1 is a Potential Mediator of Astrocytic TLR4 Signaling Activation following Acute and Chronic Focal Cerebral Ischemia.

Published in:

Neurology Research International, 2020, p. 1, doi. 10.1155/2020/3929438

By:

Famakin, Bolanle M.;
Tsymbalyuk, Orest;
Tsymbalyuk, Natalia;
Ivanova, Svetlana;
Woo, Seung Kyoon;
Kwon, Min Seong;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date.

Published in:

Drug Design, Development & Therapy, 2018, v. 12, p. 2539, doi. 10.2147/DDDT.S150043

By:

King, Zachary A;
Sheth, Kevin N;
Kimberly, W Taylor;
Simard, J Marc

Publication type:

Article

4-aminopyridine causes apoptosis and blocks an outward rectifier K+ channel in malignant astrocytoma cell lines.

Published in:

Journal of Neuroscience Research, 1997, v. 48, n. 2, p. 122, doi. 10.1002/(SICI)1097-4547(19970415)48:2<122::AID-JNR4>3.0.CO;2-E

By:

Chin, Lawrence S.;
Park, Charles C.;
Zitnay, Kevin M.;
Sinha, Manoj;
DiPatri, Arthur J.;
Perillán, Pablo;
Simard, J. Marc

Publication type:

Article

Acetyl-L-Carnitine arginyl amide (ST857) increases calcium channel density in rat pheochromocytoma (PC12) cells.

Published in:

Journal of Neuroscience Research, 1995, v. 40, n. 3, p. 371, doi. 10.1002/jnr.490400311

By:

Tewari, K.;
Simard, J. Marc;
Peng, Y. B.;
Werrbach-Perez, K.;
Perez-Polo, J. R.

Publication type:

Article

An update on the pharmacological management and prevention of cerebral edema: current therapeutic strategies.

Published in:

Expert Opinion on Pharmacotherapy, 2021, v. 22, n. 8, p. 1025, doi. 10.1080/14656566.2021.1876663

By:

Pergakis, Melissa;
Badjatia, Neeraj;
Simard, J. Marc

Publication type:

Article

TRPM4 and the Emperor.

Published in:

Channels (19336950), 2018, v. 12, n. 1, p. 174, doi. 10.1080/19336950.2017.1398967

By:

Simard, J. Marc;
Gerzanich, Volodymyr

Publication type:

Article

A large portion of the astrocyte proteome is dedicated to perivascular endfeet, including critical components of the electron transport chain.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 10, p. 2546, doi. 10.1177/0271678X211004182

By:

Stokum, Jesse A;
Shim, Bosung;
Huang, Weiliang;
Kane, Maureen;
Smith, Jesse A;
Gerzanich, Volodymyr;
Simard, J Marc

Publication type:

Article

Update on cerebrovasospasm.

Published in:

Neurosurgical Focus, 2022, v. 52, n. 3, p. 1, doi. 10.3171/2021.12.FOCUS21773

By:

Connolly Jr., E. Sander;
Mayer, Stephan A.;
Macdonald, R. Loch;
Simard, J. Marc

Publication type:

Article

Cerebrospinal fluid hypersecretion in pediatric hydrocephalus.

Published in:

Neurosurgical Focus, 2016, v. 41, n. 5, p. 1, doi. 10.3171/2016.8.FOCUS16278

By:

Karimy, Jason K.;
Duran, Daniel;
Hu, Jamie K.;
Gavankar, Charuta;
Gaillard, Jonathan R.;
Bayri, Yasar;
Rice, Hunter;
DiLuna, Michael L.;
Gerzanich, Volodymyr;
Simard, J. Marc;
Kahle, Kristopher T.

Publication type:

Article

Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02692-2

By:

Cummings, Jessica;
Wu, Yijen L.;
Dixon, C. Edward;
Henchir, Jeremy;
Simard, J. Marc;
Panigrahy, Ashok;
Kochanek, Patrick M.;
Jha, Ruchira M.;
Aneja, Rajesh K.

Publication type:

Article

Traumatic brain injury alters dendritic cell differentiation and distribution in lymphoid and non-lymphoid organs.

Published in:

Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-022-02609-5

By:

Tsymbalyuk, Orest;
Gerzanich, Volodymyr;
Simard, J. Marc;
Rathinam, Chozha Vendan

Publication type:

Article

Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury.

Published in:

2007

By:

Simard, J Marc;
Tsymbalyuk, Orest;
Ivanov, Alexander;
Ivanova, Svetlana;
Bhatta, Sergei;
Geng, Zhihua;
Woo, S Kyoon;
Gerzanich, Volodymyr

Publication type:

journal article

Endothelial sulfonylurea receptor 1-regulated NCCa-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 8, p. 2105, doi. 10.1172/JCI32041

By:

Marc Simard, J.;
Tsymbalyuk, Orest;
Ivanov, Alexander;
Ivanova, Svetlana;
Bhatta, Sergei;
Zhihua Geng;
Kyoon Woo, S.;
Gerzanich, Volodymyr

Publication type:

Article

Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling.

Published in:

Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0239-6

By:

Stokum, Jesse A.;
Mehta, Rupal I.;
Ivanova, Svetlana;
Yu, Edward;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Blast-induced brain injury in rats leads to transient vestibulomotor deficits and persistent orofacial pain.

Published in:

Brain Injury, 2018, v. 32, n. 13/14, p. 1866, doi. 10.1080/02699052.2018.1536282

By:

Studlack, Paige E.;
Keledjian, Kaspar;
Farooq, Tayyiaba;
Akintola, Titilola;
Gerzanich, Volodymyr;
Simard, J. Marc;
Keller, Asaf

Publication type:

Article

Direct versus indirect actions of ghrelin on hypothalamic NPY neurons.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184261

By:

Hashiguchi, Hiroshi;
Sheng, Zhenyu;
Routh, Vanessa;
Gerzanich, Volodymyr;
Simard, J. Marc;
Bryan, Joseph

Publication type:

Article

Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0174557

By:

Connolly, Nina P.;
Stokum, Jesse A.;
Schneider, Craig S.;
Ozawa, Tatsuya;
Xu, Su;
Galisteo, Rebeca;
Castellani, Rudolph J.;
Kim, Anthony J.;
Simard, J. Marc;
Winkles, Jeffrey A.;
Holland, Eric C.;
Woodworth, Graeme F.

Publication type:

Article

Cerebral microbleeds in a neonatal rat model.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171163

By:

Carusillo Theriault, Brianna;
Woo, Seung Kyoon;
Karimy, Jason K.;
Keledjian, Kaspar;
Stokum, Jesse A.;
Sarkar, Amrita;
Coksaygan, Turhan;
Ivanova, Svetlana;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas.

Published in:

Annals of Neurology, 2012, v. 72, n. 5, p. 799, doi. 10.1002/ana.23680

By:

Kunte, Hagen;
Busch, Markus A.;
Trostdorf, Katrin;
Vollnberg, Bernd;
Harms, Lutz;
Mehta, Rupal I.;
Castellani, Rudolf J.;
Mandava, Pitchaiah;
Kent, Thomas A.;
Simard, J. Marc

Publication type:

Article

Molecular pathophysiology of cerebral edema.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 3, p. 513, doi. 10.1177/0271678X15617172

By:

Stokum, Jesse A.;
Gerzanich, Volodymyr;
Simard, J. Marc

Publication type:

Article

Sulfonylurea receptor 1 in central nervous system injury: a focused review.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 9, p. 1699, doi. 10.1038/jcbfm.2012.91

By:

Simard, J Marc;
Woo, S Kyoon;
Schwartzbauer, Gary T;
Gerzanich, Volodymyr

Publication type:

Article

Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 3, p. 525, doi. 10.1038/jcbfm.2011.159

By:

Woo, Seung Kyoon;
Kwon, Min Seong;
Geng, Zhihua;
Chen, Zheng;
Ivanov, Alexander;
Bhatta, Sergei;
Gerzanich, Volodymyr;
Simard, J Marc

Publication type:

Article

Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.

Published in:

2009

By:

Simard, J Marc;
Geng, Zhihua;
Woo, S Kyoon;
Ivanova, Svetlana;
Tosun, Cigdem;
Melnichenko, Ludmila;
Gerzanich, Volodymyr

Publication type:

Correction Notice