Found: 16
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A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Selective targeting and protection against toxic amyloid‐beta oligomers by PMN310, a monoclonal antibody rationally designed for greater therapeutic potency in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.079734
- By:
- Publication type:
- Article
Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E: Development of new models and analysis methods/amyloid/Abeta.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043473
- By:
- Publication type:
- Article
O5‐06‐01: SELECTIVE TARGETING OF AMYLOID‐BETA OLIGOMER SPECIES BY PMN310, A MONOCLONAL ANTIBODY RATIONALLY DESIGNED FOR GREATER THERAPEUTIC POTENCY IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1628, doi. 10.1016/j.jalz.2019.06.4864
- By:
- Publication type:
- Article
P2‐048: HUMANIZED PMN310 SHOWS ENHANCED THERAPEUTIC POTENTIAL BY BINDING TOXIC LOW MOLECULAR WEIGHT Aβ OLIGOMERS WHILE AVOIDING ARIA‐RELATED BINDING TO Aβ DEPOSITS IN AD PATIENT BRAINS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P685, doi. 10.1016/j.jalz.2018.06.732
- By:
- Publication type:
- Article
TARGETING OF TOXIC AMYLOID-BETA OLIGOMER SPECIES BY MONOCLONAL ANTIBODY PMN310: PRECISION DRUG DESIGN FOR ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P592, doi. 10.1016/j.jalz.2017.07.225
- By:
- Publication type:
- Article
PROPAGATIVE TOXIC Aβ OLIGOMER SUBCLASS IDENTIFIED AND DEFINED BY SOLVENT ORIENTATION OF THE LYSINE 28 SIDE CHAIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1003, doi. 10.1016/j.jalz.2017.06.1394
- By:
- Publication type:
- Article
NOVEL AMYLOID-β OLIGOMER-SPECIFIC EPITOPES: A HYPOTHESIS DRIVEN APPROACH TO ALZHEIMER'S IMMUNOTHERAPEUTICS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1191, doi. 10.1016/j.jalz.2016.07.145
- By:
- Publication type:
- Article
THE AMYLOID-BETA (Aβ) OLIGOMER-SPECIFIC CYCLIC-SER-ASN-LYS (CSNK) TRIPEPTIDE IS HIGHLY IMMUNOGENIC AND INDUCES SUSTAINED LEVELS OF ANTI-CSNK ANTIBODIES OF THE IGG1 SUBCLASS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P834, doi. 10.1016/j.jalz.2016.06.1705
- By:
- Publication type:
- Article
A COMPUTATIONAL METHOD TO PREDICT DISEASE-SPECIFIC EPITOPES IN Aβ, AND ITS APPLICATION TO OLIGOMER-SELECTIVE ANTIBODIES FOR ALZHEIMER’S IMMUNOTHERAPY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1148, doi. 10.1016/j.jalz.2016.07.042
- By:
- Publication type:
- Article
An amyloid-beta oligomer epitope specific for toxic assemblages in Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P136, doi. 10.1016/j.jalz.2015.07.054
- By:
- Publication type:
- Article
Characterization of a humanized amyloid beta oligomer monoclonal antibody (5E3) under preclinical development for passive immunotherapy of Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P275, doi. 10.1016/j.jalz.2015.07.363
- By:
- Publication type:
- Article
Epitope-specific amyloid-β oligomer vaccination ameliorates amygdala-dependent memory deficits and inhibits region-to-region spread of plaque pathology in APP/PS1 mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P904, doi. 10.1016/j.jalz.2015.08.144
- By:
- Publication type:
- Article
A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer's Disease.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46306-5
- By:
- Publication type:
- Article
Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates.
- Published in:
- PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0232266
- By:
- Publication type:
- Article
Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00366-8
- By:
- Publication type:
- Article