Works by Silginer, Manuela

Results: 18

Targeting the IDH1<sup>R132H</sup> mutation in gliomas by CRISPR/Cas precision base editing.

Published in:

Neuro-Oncology Advances, 2024, v. 6, n. 1, p. 1, doi. 10.1093/noajnl/vdae182

By:

Weber, Remi;
Vasella, Flavio;
Klimko, Artsiom;
Silginer, Manuela;
Lamfers, Martine;
Neidert, Marian Christoph;
Regli, Luca;
Schwank, Gerald;
Weller, Michael

Publication type:

Article

Programmed death ligand 1 gene silencing in murine glioma models reveals cell line-specific modulation of tumor growth in vivo.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac148

By:

Blomberg, Evelina;
Silginer, Manuela;
Roth, Patrick;
Weller, Michael

Publication type:

Article

A T-cell antigen atlas for meningioma: novel options for immunotherapy.

Published in:

Acta Neuropathologica, 2023, v. 146, n. 2, p. 173, doi. 10.1007/s00401-023-02605-w

By:

Medici, Gioele;
Freudenmann, Lena K.;
Velz, Julia;
Wang, Sophie Shih-Yüng;
Kapolou, Konstantina;
Paramasivam, Nagarajan;
Mühlenbruch, Lena;
Kowalewski, Daniel J.;
Vasella, Flavio;
Bilich, Tatjana;
Frey, Beat M.;
Dubbelaar, Marissa L.;
Patterson, Angelica Brooke;
Zeitlberger, Anna Maria;
Silginer, Manuela;
Roth, Patrick;
Weiss, Tobias;
Wirsching, Hans-Georg;
Krayenbühl, Niklaus;
Bozinov, Oliver

Publication type:

Article

The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy.

Published in:

Acta Neuropathologica, 2018, v. 135, n. 6, p. 923, doi. 10.1007/s00401-018-1836-9

By:

Neidert, Marian Christoph;
Kowalewski, Daniel Johannes;
Silginer, Manuela;
Kapolou, Konstantina;
Backert, Linus;
Freudenmann, Lena Katharina;
Peper, Janet Kerstin;
Marcu, Ana;
Wang, Sophie Shih-Yüng;
Walz, Juliane Sarah;
Wolpert, Fabian;
Rammensee, Hans-Georg;
Henschler, Reinhard;
Lamszus, Katrin;
Westphal, Manfred;
Roth, Patrick;
Regli, Luca;
Stevanović, Stefan;
Weller, Michael;
Eisele, Günter

Publication type:

Article

Chimeric antigen receptor T cell-based targeting of CD317 as a novel immunotherapeutic strategy against glioblastoma.

Published in:

Neuro-Oncology, 2023, v. 25, n. 11, p. 2001, doi. 10.1093/neuonc/noad108

By:

Hänsch, Lena;
Peipp, Matthias;
Mastall, Maximilian;
Villars, Danielle;
Myburgh, Renier;
Silginer, Manuela;
Weiss, Tobias;
Gramatzki, Dorothee;
Vasella, Flavio;
Manz, Markus G;
Weller, Michael;
Roth, Patrick

Publication type:

Article

The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.

Published in:

Cell Death & Disease, 2021, v. 12, n. 10, p. 1, doi. 10.1038/s41419-021-04146-0

By:

Ahmadov, Ulvi;
Picard, Daniel;
Bartl, Jasmin;
Silginer, Manuela;
Trajkovic-Arsic, Marija;
Qin, Nan;
Blümel, Lena;
Wolter, Marietta;
Lim, Jonathan K. M.;
Pauck, David;
Winkelkotte, Alina Marie;
Melcher, Marlen;
Langini, Maike;
Marquardt, Viktoria;
Sander, Felix;
Stefanski, Anja;
Steltgens, Sascha;
Hassiepen, Christina;
Kaufhold, Anna;
Meyer, Frauke-Dorothee

Publication type:

Article

Interferon-β sensitizes human glioblastoma cells to the cyclin-dependent kinase inhibitor, TG02.

Published in:

Oncology Letters, 2020, v. 19, n. 4, p. 2649, doi. 10.3892/ol.2020.11362

By:

LOHMANN, BIRTHE;
RHUN, EMILIE LE;
SILGINER, MANUELA;
EPSKAMP, MIRKA;
WELLER, MICHAEL

Publication type:

Article

IMMU-53. IMPACT OF TUMOR-TREATING FIELDS (TTFIELDS) ON THE IMMUNOGENICITY OF GLIOMA CELLS.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi133, doi. 10.1093/neuonc/noy148.556

By:

Silginer, Manuela;
Weller, Michael;
Roth, Patrick

Publication type:

Article

Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma.

Published in:

Neuro-Oncology, 2017, v. 19, n. 10, p. 1338, doi. 10.1093/neuonc/nox051

By:

Silginer, Manuela;
Nagy, Sara;
Happold, Caroline;
Schneider, Hannah;
Weller, Michael;
Roth, Patrick

Publication type:

Article

Integrin control of the transforming growth factor-[beta] pathway in glioblastoma.

Published in:

2013

By:

Roth, Patrick;
Silginer, Manuela;
Goodman, Simon L;
Hasenbach, Kathy;
Thies, Svenja;
Maurer, Gabriele;
Schraml, Peter;
Tabatabai, Ghazaleh;
Moch, Holger;
Tritschler, Isabel;
Weller, Michael

Publication type:

Journal Article

Integrin control of the transforming growth factor-β pathway in glioblastoma.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 2, p. 564, doi. 10.1093/brain/aws351

By:

Roth, Patrick;
Silginer, Manuela;
Goodman, Simon L.;
Hasenbach, Kathy;
Thies, Svenja;
Maurer, Gabriele;
Schraml, Peter;
Tabatabai, Ghazaleh;
Moch, Holger;
Tritschler, Isabel;
Weller, Michael

Publication type:

Article

Immunocytokines are a promising immunotherapeutic approach against glioblastoma.

Published in:

Science Translational Medicine, 2020, v. 12, n. 564, p. 1, doi. 10.1126/scitranslmed.abb2311

By:

Weiss, Tobias;
Puca, Emanuele;
Silginer, Manuela;
Hemmerle, Teresa;
Pazahr, Shila;
Bink, Andrea;
Weller, Michael;
Neri, Dario;
Roth, Patrick

Publication type:

Article

CRISPR/Cas9-mediated abrogation of CD95L/CD95 signaling-induced glioma cell growth and immunosuppression increases survival in murine glioma models.

Published in:

Journal of Neuro-Oncology, 2022, v. 160, n. 2, p. 299, doi. 10.1007/s11060-022-04137-x

By:

Quijano-Rubio, Clara;
Silginer, Manuela;
Weller, Michael

Publication type:

Article

CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner.

Published in:

Cell Death Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41420-022-01133-y

By:

Quijano-Rubio, Clara;
Silginer, Manuela;
Weller, Michael

Publication type:

Article

Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition.

Published in:

Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01527-8

By:

Silginer, Manuela;
Papa, Eleanna;
Szabó, Emese;
Vasella, Flavio;
Pruschy, Martin;
Stroh, Christopher;
Roth, Patrick;
Weiss, Tobias;
Weller, Michael

Publication type:

Article

Transcriptional control of O<sup>6</sup>‐methylguanine DNA methyltransferase expression and temozolomide resistance in glioblastoma.

Published in:

Journal of Neurochemistry, 2018, v. 144, n. 6, p. 780, doi. 10.1111/jnc.14326

By:

Happold, Caroline;
Stojcheva, Nina;
Silginer, Manuela;
Weiss, Tobias;
Roth, Patrick;
Reifenberger, Guido;
Weller, Michael

Publication type:

Article

Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.

Published in:

Journal of Neurochemistry, 2012, v. 122, n. 2, p. 444, doi. 10.1111/j.1471-4159.2012.07781.x

By:

Happold, Caroline;
Roth, Patrick;
Wick, Wolfgang;
Schmidt, Natalie;
Florea, Ana-Maria;
Silginer, Manuela;
Reifenberger, Guido;
Weller, Michael

Publication type:

Article

Profound, durable and MGMT‐independent sensitivity of glioblastoma cells to cyclin‐dependent kinase inhibition.

Published in:

International Journal of Cancer, 2019, v. 145, n. 1, p. 242, doi. 10.1002/ijc.32069

By:

Le Rhun, Emilie;
Achenbach, Caroline;
Lohmann, Birthe;
Silginer, Manuela;
Schneider, Hannah;
Meetze, Kristan;
Szabo, Emese;
Weller, Michael

Publication type:

Article