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Polymorphismus von Amyloidfibrillen in vivo.
Published in:
Angewandte Chemie, 2016, v. 128, n. 15, p. 4903, doi. 10.1002/ange.201511524
By:
- Annamalai, Karthikeyan;
- Gührs, Karl ‐ Heinz;
- Koehler, Rolf;
- Schmidt, Matthias;
- Michel, Henri;
- Loos, Cornelia;
- Gaffney, Patricia M.;
- Sigurdson, Christina J.;
- Hegenbart, Ute;
- Schönland, Stefan;
- Fändrich, Marcus
Publication type:
Article
Polymorphism of Amyloid Fibrils In Vivo.
Published in:
Angewandte Chemie International Edition, 2016, v. 55, n. 15, p. 4822, doi. 10.1002/anie.201511524
By:
- Annamalai, Karthikeyan;
- Gührs, Karl-Heinz;
- Koehler, Rolf;
- Schmidt, Matthias;
- Michel, Henri;
- Loos, Cornelia;
- Gaffney, Patricia M.;
- Sigurdson, Christina J.;
- Hegenbart, Ute;
- Schönland, Stefan;
- Fändrich, Marcus
Publication type:
Article
A molecular switch controls interspecies prion disease transmission in mice.
Published in:
2010
By:
- Sigurdson, Christina J.;
- Nilsson, K. Peter R.;
- Hornemann, Simone;
- Manco, Giuseppe;
- Fernández-Borges, Natalia;
- Schwarz, Petra;
- Castilla, Joaquín;
- Wüthrich, Kurt;
- Aguzzi, Adriano;
- Fernández-Borges, Natalia;
- Castilla, Joaquín;
- Wüthrich, Kurt
Publication type:
journal article
PrP<sup>Sc</sup> in mammary glands of sheep affected by scrapie and mastitis.
Published in:
2005
By:
- Ligios, Ciriaco;
- Sigurdson, Christina J.;
- Santucciu, Cinzia;
- Carcassola, Gabriella;
- Manco, Giuseppe;
- Basagni, Massimo;
- Maestrale, Caterina;
- Cancedda, Maria Giovanna;
- Madau, Laura;
- Aguzzi, Adriano
Publication type:
Letter
Prion strain discrimination using luminescent conjugated polymers.
Published in:
Nature Methods, 2007, v. 4, n. 12, p. 1023, doi. 10.1038/nmeth1131
By:
- Sigurdson, Christina J.;
- Nilsson, K Peter R.;
- Hornemann, Simone;
- Manco, Giuseppe;
- Polymenidou, Magdalini;
- Schwarz, Petra;
- Leclerc, Mario;
- Hammarström, Per;
- Wüthrich, Kurt;
- Aguzzi, Adriano
Publication type:
Article
Enhanced neuroinvasion by smaller, soluble prions.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0430-z
By:
- Bett, Cyrus;
- Lawrence, Jessica;
- Kurt, Timothy D.;
- Orru, Christina;
- Aguilar-Calvo, Patricia;
- Kincaid, Anthony E.;
- Surewicz, Witold K.;
- Caughey, Byron;
- Chengbiao Wu;
- Sigurdson, Christina J.
Publication type:
Article
Post-translational modifications in PrP expand the conformational diversity of prions in vivo.
Published in:
Scientific Reports, 2017, p. 43295, doi. 10.1038/srep43295
By:
- Aguilar-Calvo, Patricia;
- Xiao, Xiangzhu;
- Bett, Cyrus;
- Eraña, Hasier;
- Soldau, Katrin;
- Castilla, Joaquin;
- Nilsson, K. Peter R.;
- Surewicz, Witold K.;
- Sigurdson, Christina J.
Publication type:
Article
Experimental Oral Transmission of Chronic Wasting Disease to Reindeer (Rangifer tarandus tarandus).
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039055
By:
- Mitchell, Gordon B.;
- Sigurdson, Christina J.;
- O'Rourke, Katherine I.;
- Algire, James;
- Harrington, Noel P.;
- Walther, Ines;
- Spraker, Terry R.;
- Balachandran, Aru
Publication type:
Article
Bacterial colitis increases susceptibility to oral prion disease.
Published in:
2009
By:
- Sigurdson, Christina J.;
- Heikenwalder, Mathias;
- Manco, Giuseppe;
- Barthel, Manja;
- Schwarz, Petra;
- Stecher, Bärbel;
- Krautler, Nike J.;
- Hardt, Wolf-Dietrich;
- Seifert, Burkhardt;
- MacPherson, Andrew J. S.;
- Corthesy, Irène;
- Aguzzi, Adriano;
- Stecher, Bärbel;
- Corthesy, Irène
Publication type:
journal article
Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission.
Published in:
PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009123
By:
- Aguilar-Calvo, Patricia;
- Callender, Julia A.;
- Sigurdson, Christina J.
Publication type:
Article
Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12683-8
By:
- Kollmer, Marius;
- Close, William;
- Funk, Leonie;
- Rasmussen, Jay;
- Bsoul, Aref;
- Schierhorn, Angelika;
- Schmidt, Matthias;
- Sigurdson, Christina J.;
- Jucker, Mathias;
- Fändrich, Marcus
Publication type:
Article
Prion Strain Interactions Are Highly Selective.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 36, p. 12094, doi. 10.1523/JNEUROSCI.2417-10.2010
By:
- Nilsson, K. Peter R.;
- Joshi-Barr, Shivanjali;
- Winson, Olivia;
- Sigurdson, Christina J.
Publication type:
Article
Antiprion immunotherapy: to suppress or to stimulate?
Published in:
Nature Reviews Immunology, 2004, v. 4, n. 9, p. 725, doi. 10.1038/nri1437
By:
- Aguzzi, Adriano;
- Sigurdson, Christina J.
Publication type:
Article
TDP43 pathology in chronic traumatic encephalopathy retinas.
Published in:
Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01650-6
By:
- Phansalkar, Ragini;
- Goodwill, Vanessa S.;
- Nirschl, Jeffrey J.;
- De Lillo, Chiara;
- Choi, Jihee;
- Spurlock, Elizabeth;
- Coughlin, David G.;
- Pizzo, Donald;
- Sigurdson, Christina J.;
- Hiniker, Annie;
- Alvarez, Victor E.;
- Mckee, Ann C.;
- Lin, Jonathan H.
Publication type:
Article
Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats.
Published in:
FASEB Journal, 2015, v. 29, n. 3, p. 911, doi. 10.1096/fj.14-256081
By:
- Gaffney, Patricia M.;
- Barr, Bradd;
- Rowe, Joan D.;
- Bett, Cyrus;
- Drygiannakis, Ioannis;
- Giannitti, Federico;
- Trejo, Margarita;
- Ghassemian, Majid;
- Martin, Patrice;
- Masliah, Eliezer;
- Sigurdson, Christina J.
Publication type:
Article
Structure of the β2-α2 loop and interspecies prion transmission.
Published in:
FASEB Journal, 2012, v. 26, n. 7, p. 2868, doi. 10.1096/fj.11-200923
By:
- Bett, Cyrus;
- Fernández-Borges, Natalia;
- Kurt, Timothy D.;
- Lucero, Melanie;
- Nilsson, K. Peter R.;
- Castilla, Joaquín;
- Sigurdson, Christina J.
Publication type:
Article
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Published in:
2020
By:
- Sevillano, Alejandro M.;
- Aguilar-Calvo, Patricia;
- Kurt, Timothy D.;
- Lawrence, Jessica A.;
- Soldau, Katrin;
- Nam, Thu H.;
- Schumann, Taylor;
- Pizzo, Donald P.;
- Nyström, Sofie;
- Choudhury, Biswa;
- Altmeppen, Hermann;
- Esko, Jeffrey D.;
- Glatzel, Markus;
- Nilsson, K. Peter R.;
- Sigurdson, Christina J.
Publication type:
journal article
Human prion protein sequence elements impede cross-species chronic wasting disease transmission.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1485, doi. 10.1172/JCI79408
By:
- Kurt, Timothy D.;
- Lin Jiang;
- Fernández-Borges, Natalia;
- Bett, Cyrus;
- Jun Liu;
- Yang, Tom;
- Spraker, Terry R.;
- Castilla, Joaquín;
- Eisenberg, David;
- Qingzhong Kong;
- Sigurdson, Christina J.
Publication type:
Article
Structural consequences of sequence variation in mammalian prion b2α2 loop segments.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.960322
By:
- Glynn, Calina;
- Hernandez, Evelyn;
- Gallagher-Jones, Marcus;
- Miao, Jennifer;
- Sigurdson, Christina J.;
- Rodriguez, Jose A.
Publication type:
Article
Recent advances on the molecular pathogenesis of prion diseases.
Published in:
Brain Pathology, 2019, v. 29, n. 2, p. 245, doi. 10.1111/bpa.12693
By:
- Glatzel, Markus;
- Sigurdson, Christina J.
Publication type:
Article
Generation of novel neuroinvasive prions following intravenous challenge.
Published in:
Brain Pathology, 2018, v. 28, n. 6, p. 999, doi. 10.1111/bpa.12598
By:
- Aguilar‐Calvo, Patricia;
- Bett, Cyrus;
- Sevillano, Alejandro M.;
- Kurt, Timothy D.;
- Lawrence, Jessica;
- Soldau, Katrin;
- Hammarström, Per;
- Nilsson, K. Peter R.;
- Sigurdson, Christina J.
Publication type:
Article
Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions.
Published in:
PLoS Pathogens, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.ppat.1003280
By:
- Bett, Cyrus;
- Kurt, Tim D.;
- Lucero, Melanie;
- Trejo, Margarita;
- Rozemuller, Annemieke J.;
- Kong, Qingzhong;
- Nilsson, K. Peter R.;
- Masliah, Eliezer;
- Oldstone, Michael B.;
- Sigurdson, Christina J.
Publication type:
Article
Biochemical Properties of Highly Neuroinvasive Prion Strains.
Published in:
PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002522
By:
- Bett, Cyrus;
- Joshi-Barr, Shivanjali;
- Lucero, Melanie;
- Trejo, Margarita;
- Liberski, Pawel;
- Kelly, Jeffery W.;
- Masliah, Eliezer;
- Sigurdson, Christina J.
Publication type:
Article
Other animal prion diseases.
Published in:
British Medical Bulletin, 2003, v. 66, n. 1, p. 199, doi. 10.1093/bmb/66.1.199
By:
- Christina J Sigurdson;
- Michael W Miller
Publication type:
Article
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.
Published in:
Acta Neuropathologica, 2020, v. 139, n. 3, p. 527, doi. 10.1007/s00401-019-02085-x
By:
- Aguilar-Calvo, Patricia;
- Sevillano, Alejandro M.;
- Bapat, Jaidev;
- Soldau, Katrin;
- Sandoval, Daniel R.;
- Altmeppen, Hermann C.;
- Linsenmeier, Luise;
- Pizzo, Donald P.;
- Geschwind, Michael D.;
- Sanchez, Henry;
- Appleby, Brian S.;
- Cohen, Mark L.;
- Safar, Jiri G.;
- Edland, Steven D.;
- Glatzel, Markus;
- Nilsson, K. Peter R.;
- Esko, Jeffrey D.;
- Sigurdson, Christina J.
Publication type:
Article
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease.
Published in:
Acta Neuropathologica, 2019, v. 137, n. 4, p. 585, doi. 10.1007/s00401-018-1947-3
By:
- Kraus, Allison;
- Saijo, Eri;
- Metrick, Michael A.;
- Caughey, Byron;
- Newell, Kathy;
- Sigurdson, Christina J.;
- Zanusso, Gianluigi;
- Ghetti, Bernardino
Publication type:
Article
A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates.
Published in:
Chemistry - A European Journal, 2015, v. 21, n. 43, p. 15133, doi. 10.1002/chem.201502999
By:
- Shirani, Hamid;
- Linares, Mathieu;
- Sigurdson, Christina J.;
- Lindgren, Mikael;
- Norman, Patrick;
- Nilsson, K. Peter R.
Publication type:
Article
The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates.
Published in:
Chemistry - A European Journal, 2013, v. 19, n. 31, p. 10179, doi. 10.1002/chem.201301463
By:
- Klingstedt, Therése;
- Shirani, Hamid;
- Åslund, K. O. Andreas;
- Cairns, Nigel J.;
- Sigurdson, Christina J.;
- Goedert, Michel;
- Nilsson, K. Peter R.
Publication type:
Article
Prion Transmission Prevented by Modifying the β2-α2 Loop Structure of Host PrP<sup>C</sup>.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 3, p. 1022, doi. 10.1523/JNEUROSCI.4636-13.2014
By:
- Kurt, Timothy D.;
- Bett, Cyrus;
- Fernández-Borges, Natalia;
- Joshi-Barr, Shivanjali;
- Hornemann, Simone;
- Rülicke, Thomas;
- Castilla, Joaquín;
- Wüthrich, Kurt;
- Aguzzi, Adriano;
- Sigurdson, Christina J.
Publication type:
Article
Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein
Published in:
Journal of Neuroscience, 2011, v. 31, n. 39, p. 13840, doi. 10.1523/jneurosci.3504-11.2011
By:
- Sigurdson, Christina J.;
- Joshi-Barr, Shivanjali;
- Bett, Cyrus;
- Winson, Olivia;
- Manco, Giuseppe;
- Schwarz, Petra;
- Rülicke, Thomas;
- R. Nilsson, K. Peter;
- Margalith, Ilan;
- Raeber, Alex;
- Peretz, David;
- Hornemann, Simone;
- Wüthrich, Kurt;
- Aguzzi, Adriano
Publication type:
Article
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
Published in:
PLoS Pathogens, 2023, v. 19, n. 9, p. 1, doi. 10.1371/journal.ppat.1011487
By:
- Aguilar-Calvo, Patricia;
- Malik, Adela;
- Sandoval, Daniel R.;
- Barback, Christopher;
- Orrù, Christina D.;
- Standke, Heidi G.;
- Thomas, Olivia R.;
- Dwyer, Chrissa A.;
- Pizzo, Donald P.;
- Bapat, Jaidev;
- Soldau, Katrin;
- Ogawa, Ryotaro;
- Riley, Mckenzie B.;
- Nilsson, K. Peter R.;
- Kraus, Allison;
- Caughey, Byron;
- Iliff, Jeffrey J.;
- Vera, David R.;
- Esko, Jeffrey D.;
- Sigurdson, Christina J.
Publication type:
Article

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