Works by Sievers, Sonja

Results: 55

An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products.

Published in:

ChemBioChem, 2025, v. 26, n. 10, p. 1, doi. 10.1002/cbic.202500182

By:

Hoock, Joseph G. F.;
Burhop, Annina;
Greiner, Luca C.;
Schölermann, Beate;
Da Cruz Lopes Guita, Celine;
Liu, Jie;
Bag, Sukdev;
Pahl, Axel;
Sievers, Sonja;
Scheel, Rebecca;
Strohmann, Carsten;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Collective Synthesis of Sarpagine and Macroline Alkaloid‐Inspired Compounds.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 5, p. 1, doi. 10.1002/chem.202303027

By:

Aoyama, Hikaru;
Davies, Caitlin;
Liu, Jie;
Pahl, Axel;
Kirchhoff, Jan‐Lukas;
Scheel, Rebecca;
Sievers, Sonja;
Strohmann, Carsten;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp<sup>3</sup>‐Rich Compounds With Distinct Phenotypic Effects.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202203992

By:

Okolo, Ephraim A.;
Pahl, Axel;
Sievers, Sonja;
Pask, Christopher M.;
Nelson, Adam;
Marsden, Stephen P.

Publication type:

Article

Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202202164

By:

Grigalunas, Michael;
Patil, Sohan;
Krzyzanowski, Adrian;
Pahl, Axel;
Flegel, Jana;
Schölermann, Beate;
Xie, Jianing;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

A Scaffold‐Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 68, p. 15498, doi. 10.1002/chem.201904175

By:

Zimmermann, Stefan;
Akbarzadeh, Mohammad;
Otte, Felix;
Strohmann, Carsten;
Sankar, Muthukumar Gomathi;
Ziegler, Slava;
Pahl, Axel;
Sievers, Sonja;
Kumar, Kamal

Publication type:

Article

Organokatalytische Synthese von enantiomerenreinen 2 H- und 3 H-Pyrrolen: Inhibitoren des Hedgehog-Signalwegs.

Published in:

Angewandte Chemie, 2016, v. 128, n. 27, p. 7824, doi. 10.1002/ange.201602932

By:

Kötzner, Lisa;
Leutzsch, Markus;
Sievers, Sonja;
Patil, Sumersing;
Waldmann, Herbert;
Zheng, Yiying;
Thiel, Walter;
List, Benjamin

Publication type:

Article

Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling.

Published in:

Advanced Science, 2024, v. 11, n. 21, p. 1, doi. 10.1002/advs.202309202

By:

Wang, Lin;
Yilmaz, Furkan;
Yildirim, Okan;
Schölermann, Beate;
Bag, Sukdev;
Greiner, Luca;
Pahl, Axel;
Sievers, Sonja;
Scheel, Rebecca;
Strohmann, Carsten;
Squire, Christopher;
Foley, Daniel J.;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization.

Published in:

Modern Pathology, 2006, v. 19, n. 6, p. 864, doi. 10.1038/modpathol.3800607

By:

Schneider, Dominik T.;
Zahn, Susanne;
Sievers, Sonja;
Alemazkour, Katayoun;
Reifenberger, Guido;
Wiestler, Otmar D;
Calaminus, Gabriele;
Göbel, Ulrich;
Perlman, Elizabeth J.

Publication type:

Article

Imbalances of chromosome arm 1p in pediatric and adult germ cell tumors are caused by true allelic loss: A combined comparative genomic hybridization and microsatellite analysis.

Published in:

Genes, Chromosomes & Cancer, 2006, v. 45, n. 11, p. 995, doi. 10.1002/gcc.20363

By:

Susanne Zahn;
Sonja Sievers;
Katayoun Alemazkour;
Sandra Orb;
Dieter Harms;
Wolfgang A. Schulz;
Gabriele Calaminus;
Ulrich Göbel;
Dominik T. Schneider

Publication type:

Article

IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylation‐sensitive single‐nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development.

Published in:

Genes, Chromosomes & Cancer, 2005, v. 44, n. 3, p. 256, doi. 10.1002/gcc.20237

By:

Sonja Sievers;
Katayoun Alemazkour;
Susanne Zahn;
Elizabeth J. Perlman;
Ad J. M. Gillis;
Leendert H. J. Looijenga;
Ulrich Göbel;
Dominik T. Schneider

Publication type:

Article

2‐Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 31/32, p. 5486, doi. 10.1002/ejoc.201900586

By:

Förster, Tim;
Shang, Erchang;
Shimizu, Kenshiro;
Sanada, Emiko;
Schölermann, Beate;
Huebecker, Mylene;
Hahne, Gernot;
López‐Alberca, Maria Pascual;
Janning, Petra;
Watanabe, Nobumoto;
Sievers, Sonja;
Giordanetto, Fabrizio;
Shimizu, Takeshi;
Ziegler, Slava;
Osada, Hiroyuki;
Waldmann, Herbert

Publication type:

Article

Analysis of the adenomatous polyposis coli (APC) gene in childhood and adolescent germ cell tumors.

Published in:

Pediatric Blood & Cancer, 2011, v. 56, n. 3, p. 384, doi. 10.1002/pbc.22669

By:

Okpanyi, Vera;
Schneider, Dominik T.;
Zahn, Susanne;
Sievers, Sonja;
Calaminus, Gabriele;
Nicholson, James C.;
Palmer, Roger D.;
Leuschner, Ivo;
Borkhardt, Arndt;
Schönberger, Stefan

Publication type:

Article

Phenomics‐Based Discovery of Novel Orthosteric Choline Kinase Inhibitors.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 7, p. 1, doi. 10.1002/anie.202420149

By:

Bauer, Ludwig G.;
Ward, Jennifer A.;
Díaz‐Sáez, Laura;
Sundström, Yvonne;
Tolvanen, Tuomas;
Alarcón Barrera, Juan Carlos;
Kostidis, Sarantos;
Rogers, Catherine M.;
Panagakou, Ioanna;
Singh, Usha;
Rothweiler, Elisabeth M.;
Gonzalez Orta, Alejandro;
Kaniskan, H. Ümit;
Hu, Jianping;
Jin, Jian;
Sievers, Sonja;
Waldmann, Herbert;
Giera, Martin;
Sundström, Michael;
Berg, Louise

Publication type:

Article

The Pseudo‐Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 32, p. 1, doi. 10.1002/anie.202404645

By:

Patil, Sohan;
Cremosnik, Gregor;
Dötsch, Lara;
Flegel, Jana;
Schulte, Britta;
Maier, Kerstin C.;
Žumer, Kristina;
Cramer, Patrick;
Janning, Petra;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 48, p. 1, doi. 10.1002/anie.202310222

By:

Xie, Jianing;
Pahl, Axel;
Krzyzanowski, Adrian;
Krupp, Anna;
Liu, Jie;
Koska, Sandra;
Schölermann, Beate;
Zhang, Ruirui;
Bonowski, Jana;
Sievers, Sonja;
Strohmann, Carsten;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Identification of a Novel Pseudo‐Natural Product Type IV IDO1 Inhibitor Chemotype.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 40, p. 1, doi. 10.1002/anie.202209374

By:

Davies, Caitlin;
Dötsch, Lara;
Ciulla, Maria Gessica;
Hennes, Elisabeth;
Yoshida, Kei;
Gasper, Raphael;
Scheel, Rebecca;
Sievers, Sonja;
Strohmann, Carsten;
Kumar, Kamal;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 11, p. 1, doi. 10.1002/anie.202114328

By:

Niggemeyer, Georg;
Knyazeva, Anastasia;
Gasper, Raphael;
Corkery, Dale;
Bodenbinder, Pia;
Holstein, Julian J.;
Sievers, Sonja;
Wu, Yao‐Wen;
Waldmann, Herbert

Publication type:

Article

Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 39, p. 21384, doi. 10.1002/anie.202106654

By:

Liu, Jie;
Flegel, Jana;
Otte, Felix;
Pahl, Axel;
Sievers, Sonja;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas.

Published in:

International Journal of Cancer, 2010, v. 126, n. 11, p. 2584, doi. 10.1002/ijc.24981

By:

Götze, Silke;
Wolter, Marietta;
Reifenberger, Guido;
Müller, Oliver;
Sievers, Sonja

Publication type:

Article

Phänomik‐basierte Entdeckung neuer orthosterischer Cholinkinase Inhibitoren.

Published in:

Angewandte Chemie, 2025, v. 137, n. 7, p. 1, doi. 10.1002/ange.202420149

By:

Bauer, Ludwig G.;
Ward, Jennifer A.;
Díaz‐Sáez, Laura;
Sundström, Yvonne;
Tolvanen, Tuomas;
Alarcón Barrera, Juan Carlos;
Kostidis, Sarantos;
Rogers, Catherine M.;
Panagakou, Ioanna;
Singh, Usha;
Rothweiler, Elisabeth M.;
Gonzalez Orta, Alejandro;
Kaniskan, H. Ümit;
Hu, Jianping;
Jin, Jian;
Sievers, Sonja;
Waldmann, Herbert;
Giera, Martin;
Sundström, Michael;
Berg, Louise

Publication type:

Article

The Pseudo‐Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.

Published in:

Angewandte Chemie, 2024, v. 136, n. 32, p. 1, doi. 10.1002/ange.202404645

By:

Patil, Sohan;
Cremosnik, Gregor;
Dötsch, Lara;
Flegel, Jana;
Schulte, Britta;
Maier, Kerstin C.;
Žumer, Kristina;
Cramer, Patrick;
Janning, Petra;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.

Published in:

Angewandte Chemie, 2023, v. 135, n. 48, p. 1, doi. 10.1002/ange.202310222

By:

Xie, Jianing;
Pahl, Axel;
Krzyzanowski, Adrian;
Krupp, Anna;
Liu, Jie;
Koska, Sandra;
Schölermann, Beate;
Zhang, Ruirui;
Bonowski, Jana;
Sievers, Sonja;
Strohmann, Carsten;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Identification of a Novel Pseudo‐Natural Product Type IV IDO1 Inhibitor Chemotype.

Published in:

Angewandte Chemie, 2022, v. 134, n. 40, p. 1, doi. 10.1002/ange.202209374

By:

Davies, Caitlin;
Dötsch, Lara;
Ciulla, Maria Gessica;
Hennes, Elisabeth;
Yoshida, Kei;
Gasper, Raphael;
Scheel, Rebecca;
Sievers, Sonja;
Strohmann, Carsten;
Kumar, Kamal;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Natural product fragment combination to performance-diverse pseudo-natural products.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22174-4

By:

Grigalunas, Michael;
Burhop, Annina;
Zinken, Sarah;
Pahl, Axel;
Gally, José-Manuel;
Wild, Niklas;
Mantel, Yannik;
Sievers, Sonja;
Foley, Daniel J.;
Scheel, Rebecca;
Strohmann, Carsten;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype.

Published in:

Advanced Science, 2021, v. 8, n. 19, p. 1, doi. 10.1002/advs.202102042

By:

Burhop, Annina;
Bag, Sukdev;
Grigalunas, Michael;
Woitalla, Sophie;
Bodenbinder, Pia;
Brieger, Lukas;
Strohmann, Carsten;
Pahl, Axel;
Sievers, Sonja;
Waldmann, Herbert

Publication type:

Article

LIN28‐Targeting Chromenopyrazoles and Tetrahydroquinolines Induced Cellular Morphological Changes and Showed High Biosimilarity with BRD PROTACs.

Published in:

ChemMedChem, 2025, v. 20, n. 1, p. 1, doi. 10.1002/cmdc.202400547

By:

Jiang, Mao;
Giannino, Nicole;
Goebel, Georg L.;
Sievers, Sonja;
Wu, Peng

Publication type:

Article

Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 18, p. 1, doi. 10.1002/chem.202404006

By:

Binici, Aylin;
Hennes, Elisabeth;
Koska, Sandra;
Alexander Niemann, Jens;
Reich, Alisa;
Pfaff, Christiane;
Sievers, Sonja;
Stefanie Kahnt, Astrid;
Thomas, Dominique;
Ziegler, Slava;
Watzl, Carsten;
Waldmann, Herbert

Publication type:

Article

Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation.

Published in:

Angewandte Chemie, 2022, v. 134, n. 11, p. 1, doi. 10.1002/ange.202114328

By:

Niggemeyer, Georg;
Knyazeva, Anastasia;
Gasper, Raphael;
Corkery, Dale;
Bodenbinder, Pia;
Holstein, Julian J.;
Sievers, Sonja;
Wu, Yao‐Wen;
Waldmann, Herbert

Publication type:

Article

Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids.

Published in:

Angewandte Chemie, 2021, v. 133, n. 39, p. 21554, doi. 10.1002/ange.202106654

By:

Liu, Jie;
Flegel, Jana;
Otte, Felix;
Pahl, Axel;
Sievers, Sonja;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Cell‐Based Identification of New IDO1 Modulator Chemotypes.

Published in:

Angewandte Chemie, 2021, v. 133, n. 18, p. 9957, doi. 10.1002/ange.202016004

By:

Hennes, Elisabeth;
Lampe, Philipp;
Dötsch, Lara;
Bruning, Nora;
Pulvermacher, Lisa‐Marie;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products.

Published in:

Angewandte Chemie, 2021, v. 133, n. 9, p. 4698, doi. 10.1002/ange.202013731

By:

Liu, Jie;
Cremosnik, Gregor S.;
Otte, Felix;
Pahl, Axel;
Sievers, Sonja;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor.

Published in:

Angewandte Chemie, 2020, v. 132, n. 14, p. 5770, doi. 10.1002/ange.201913712

By:

Laraia, Luca;
Garivet, Guillaume;
Foley, Daniel J.;
Kaiser, Nadine;
Müller, Sebastian;
Zinken, Sarah;
Pinkert, Thomas;
Wilke, Julian;
Corkery, Dale;
Pahl, Axel;
Sievers, Sonja;
Janning, Petra;
Arenz, Christoph;
Wu, Yaowen;
Rodriguez, Raphaël;
Waldmann, Herbert

Publication type:

Article

Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3.

Published in:

Angewandte Chemie, 2019, v. 131, n. 47, p. 17172, doi. 10.1002/ange.201909518

By:

Ceballos, Javier;
Schwalfenberg, Melanie;
Karageorgis, George;
Reckzeh, Elena S.;
Sievers, Sonja;
Ostermann, Claude;
Pahl, Axel;
Sellstedt, Magnus;
Nowacki, Jessica;
Carnero Corrales, Marjorie A.;
Wilke, Julian;
Laraia, Luca;
Tschapalda, Kirsten;
Metz, Malte;
Sehr, Dominik A.;
Brand, Silke;
Winklhofer, Konstanze;
Janning, Petra;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Design, Synthesis, and Phenotypic Profiling of Pyrano‐Furo‐Pyridone Pseudo Natural Products.

Published in:

Angewandte Chemie, 2019, v. 131, n. 41, p. 14857, doi. 10.1002/ange.201907853

By:

Christoforow, Andreas;
Wilke, Julian;
Binici, Aylin;
Pahl, Axel;
Ostermann, Claude;
Sievers, Sonja;
Waldmann, Herbert

Publication type:

Article

Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

Published in:

Angewandte Chemie, 2019, v. 131, n. 4, p. 1074, doi. 10.1002/ange.201810312

By:

Němec, Václav;
Hylsová, Michaela;
Maier, Lukáš;
Flegel, Jana;
Sievers, Sonja;
Ziegler, Slava;
Schröder, Martin;
Berger, Benedict‐Tilman;
Chaikuad, Apirat;
Valčíková, Barbora;
Uldrijan, Stjepan;
Drápela, Stanislav;
Souček, Karel;
Waldmann, Herbert;
Knapp, Stefan;
Paruch, Kamil

Publication type:

Article

Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma.

Published in:

Biomedicines, 2023, v. 11, n. 7, p. 2054, doi. 10.3390/biomedicines11072054

By:

Shamloo, Sama;
Kloetgen, Andreas;
Petroulia, Stavroula;
Hockemeyer, Kathryn;
Sievers, Sonja;
Tsirigos, Aristotelis;
Aifantis, Ioannis;
Imig, Jochen

Publication type:

Article

Profiling Cellular Morphological Changes Induced by Dual‐Targeting PROTACs of Aurora Kinase and RNA‐Binding Protein YTHDF2.

Published in:

ChemBioChem, 2024, v. 25, n. 19, p. 1, doi. 10.1002/cbic.202400183

By:

Goebel, Georg L.;
Giannino, Nicole;
Lampe, Philipp;
Qiu, Xiaqiu;
Schloßhauer, Jeffrey L.;
Imig, Jochen;
Sievers, Sonja;
Wu, Peng

Publication type:

Article

Inducin Triggers LC3‐Lipidation and ESCRT‐Mediated Lysosomal Membrane Repair.

Published in:

ChemBioChem, 2023, v. 24, n. 24, p. 1, doi. 10.1002/cbic.202300579

By:

Corkery, Dale;
Ursu, Andrei;
Lucas, Belén;
Grigalunas, Michael;
Kriegler, Simon;
Oliva, Rosario;
Dec, Robert;
Koska, Sandra;
Pahl, Axel;
Sievers, Sonja;
Ziegler, Slava;
Winter, Roland;
Wu, Yao‐Wen;
Waldmann, Herbert

Publication type:

Article

Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells.

Published in:

International Journal of Oncology, 2014, v. 45, n. 4, p. 1715, doi. 10.3892/ijo.2014.2550

By:

GÖTZE, SILKE;
COERSMEYER, MONIQUE;
MÜLLER, OLIVER;
SIEVERS, SONJA

Publication type:

Article

Cell‐Based Identification of New IDO1 Modulator Chemotypes.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 18, p. 9869, doi. 10.1002/anie.202016004

By:

Hennes, Elisabeth;
Lampe, Philipp;
Dötsch, Lara;
Bruning, Nora;
Pulvermacher, Lisa‐Marie;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 9, p. 4648, doi. 10.1002/anie.202013731

By:

Liu, Jie;
Cremosnik, Gregor S.;
Otte, Felix;
Pahl, Axel;
Sievers, Sonja;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 14, p. 5721, doi. 10.1002/anie.201913712

By:

Laraia, Luca;
Garivet, Guillaume;
Foley, Daniel J.;
Kaiser, Nadine;
Müller, Sebastian;
Zinken, Sarah;
Pinkert, Thomas;
Wilke, Julian;
Corkery, Dale;
Pahl, Axel;
Sievers, Sonja;
Janning, Petra;
Arenz, Christoph;
Wu, Yaowen;
Rodriguez, Raphaël;
Waldmann, Herbert

Publication type:

Article

Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 47, p. 17016, doi. 10.1002/anie.201909518

By:

Ceballos, Javier;
Schwalfenberg, Melanie;
Karageorgis, George;
Reckzeh, Elena S.;
Sievers, Sonja;
Ostermann, Claude;
Pahl, Axel;
Sellstedt, Magnus;
Nowacki, Jessica;
Carnero Corrales, Marjorie A.;
Wilke, Julian;
Laraia, Luca;
Tschapalda, Kirsten;
Metz, Malte;
Sehr, Dominik A.;
Brand, Silke;
Winklhofer, Konstanze;
Janning, Petra;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Design, Synthesis, and Phenotypic Profiling of Pyrano‐Furo‐Pyridone Pseudo Natural Products.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 41, p. 14715, doi. 10.1002/anie.201907853

By:

Christoforow, Andreas;
Wilke, Julian;
Binici, Aylin;
Pahl, Axel;
Ostermann, Claude;
Sievers, Sonja;
Waldmann, Herbert

Publication type:

Article

Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 4, p. 1062, doi. 10.1002/anie.201810312

By:

Němec, Václav;
Hylsová, Michaela;
Maier, Lukáš;
Flegel, Jana;
Sievers, Sonja;
Ziegler, Slava;
Schröder, Martin;
Berger, Benedict‐Tilman;
Chaikuad, Apirat;
Valčíková, Barbora;
Uldrijan, Stjepan;
Drápela, Stanislav;
Souček, Karel;
Waldmann, Herbert;
Knapp, Stefan;
Paruch, Kamil

Publication type:

Article

The Organocatalytic Approach to Enantiopure 2 H- and 3 H-Pyrroles: Inhibitors of the Hedgehog Signaling Pathway.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 27, p. 7693, doi. 10.1002/anie.201602932

By:

Kötzner, Lisa;
Leutzsch, Markus;
Sievers, Sonja;
Patil, Sumersing;
Waldmann, Herbert;
Zheng, Yiying;
Thiel, Walter;
List, Benjamin

Publication type:

Article

Identification of Biologically Diverse Tetrahydronaphthalen‐2‐ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol‐Inspired Compounds.

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ChemBioChem, 2023, v. 24, n. 5, p. 1, doi. 10.1002/cbic.202200555

By:

Whitmarsh‐Everiss, Thomas;
Wang, Zhou;
Hauberg Hansen, Cecilie;
Depta, Laura;
Sassetti, Elisa;
Rafn Dan, Oliver;
Pahl, Axel;
Sievers, Sonja;
Laraia, Luca

Publication type:

Article

Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay.

Published in:

ChemBioChem, 2022, v. 23, n. 22, p. 1, doi. 10.1002/cbic.202200475

By:

Schölermann, Beate;
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Grigalunas, Michael;
Burhop, Annina;
Xie, Yusheng;
Hoock, Joseph G. F.;
Liu, Jie;
Dow, Mark;
Nelson, Adam;
Nowak, Christine;
Pahl, Axel;
Sievers, Sonja;
Ziegler, Slava

Publication type:

Article

Polyether Cyclization Cascade Alterations in Response to Monensin Polyketide Synthase Mutations.

Published in:

ChemBioChem, 2022, v. 23, n. 2, p. 1, doi. 10.1002/cbic.202100584

By:

Heinrich, Sascha;
Grote, Marius;
Sievers, Sonja;
Kushnir, Susanna;
Schulz, Frank

Publication type:

Article

Cover Feature: Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets (ChemBioChem 22/2020).

Published in:

ChemBioChem, 2020, v. 21, n. 22, p. 3160, doi. 10.1002/cbic.202000734

By:

Schneidewind, Tabea;
Brause, Alexandra;
Pahl, Axel;
Burhop, Annina;
Mejuch, Tom;
Sievers, Sonja;
Waldmann, Herbert;
Ziegler, Slava

Publication type:

Article