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In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1241, doi. 10.3390/ph14121241
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- Publication type:
- Article
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition.
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- EMBO Molecular Medicine, 2019, v. 11, n. 10, p. N.PAG, doi. 10.15252/emmm.201910769
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- Publication type:
- Article
Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells.
- Published in:
- 2011
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- Publication type:
- journal article
Compare and contrast: pediatric cancer versus adult malignancies.
- Published in:
- Cancer & Metastasis Reviews, 2019, v. 38, n. 4, p. 673, doi. 10.1007/s10555-019-09836-y
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- Article
Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis.
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- Human Genetics, 2020, v. 139, n. 11, p. 1443, doi. 10.1007/s00439-020-02188-6
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- Publication type:
- Article
Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25501-x
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- Publication type:
- Article
A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131670
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- Publication type:
- Article
PARP Inhibition Restores Extrinsic Apoptotic Sensitivity in Glioblastoma.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114583
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- Publication type:
- Article
Novel IDH1-Targeted Glioma Therapies.
- Published in:
- 2019
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- Publication type:
- journal article
Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents.
- Published in:
- Cancers, 2021, v. 13, n. 10, p. 2504, doi. 10.3390/cancers13102504
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- Publication type:
- Article
Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma.
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- Cancers, 2020, v. 12, n. 8, p. 2137, doi. 10.3390/cancers12082137
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- Publication type:
- Article
Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors.
- Published in:
- Cancers, 2019, v. 11, n. 6, p. 788, doi. 10.3390/cancers11060788
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- Publication type:
- Article
The limitations of targeting MEK signalling in Glioblastoma therapy.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64289-6
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- Publication type:
- Article
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
- Published in:
- 2020
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- Publication type:
- journal article
Inhibition of PI3K signalling increases the efficiency of radiotherapy in glioblastoma cells.
- Published in:
- International Journal of Oncology, 2018, v. 53, n. 5, p. 1881, doi. 10.3892/ijo.2018.4528
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- Publication type:
- Article
A paired comparison between glioblastoma 'stem cells' and differentiated cells.
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- International Journal of Cancer, 2016, v. 138, n. 7, p. 1709, doi. 10.1002/ijc.29908
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- Publication type:
- Article
Dominant-negative ATF5 rapidly depletes survivin in tumor cells.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 10, p. N.PAG, doi. 10.1038/s41419-019-1872-y
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- Publication type:
- Article
Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro.
- Published in:
- British Journal of Cancer, 2024, v. 130, n. 8, p. 1365, doi. 10.1038/s41416-024-02608-8
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- Publication type:
- Article
Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APP<sup>V717I</sup> mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator.
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- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02755-5
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- Publication type:
- Article
Considering the Experimental Use of Temozolomide in Glioblastoma Research.
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- Biomedicines, 2020, v. 8, n. 6, p. 151, doi. 10.3390/biomedicines8060151
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- Publication type:
- Article
Temozolomide and Other Alkylating Agents in Glioblastoma Therapy.
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- Biomedicines, 2019, v. 7, n. 3, p. 69, doi. 10.3390/biomedicines7030069
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- Publication type:
- Article
Suppressing PD-L1 Expression via AURKA Kinase Inhibition Enhances Natural Killer Cell-Mediated Cytotoxicity against Glioblastoma.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 13, p. 1155, doi. 10.3390/cells13131155
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- Publication type:
- Article
DPEP Inhibits Cancer Cell Glucose Uptake, Glycolysis and Survival by Upregulating Tumor Suppressor TXNIP.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 12, p. 1025, doi. 10.3390/cells13121025
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- Publication type:
- Article
Targeting Transcription Factors ATF5, CEBPB and CEBPD with Cell-Penetrating Peptides to Treat Brain and Other Cancers.
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- Cells (2073-4409), 2023, v. 12, n. 4, p. 581, doi. 10.3390/cells12040581
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- Publication type:
- Article
Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma.
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- Cells (2073-4409), 2022, v. 11, n. 19, p. 2956, doi. 10.3390/cells11192956
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- Publication type:
- Article
RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 7, p. 1643, doi. 10.3390/cells10071643
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- Publication type:
- Article
Inhibition of HDAC1/2 Along with TRAP1 Causes Synthetic Lethality in Glioblastoma Model Systems.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 7, p. 1661, doi. 10.3390/cells9071661
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- Publication type:
- Article
Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00984-9
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- Publication type:
- Article
Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis.
- Published in:
- Cellular Oncology (2211-3428), 2019, v. 42, n. 3, p. 287, doi. 10.1007/s13402-019-00425-3
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- Publication type:
- Article
MGMT promoter methylation in 1p19q-intact gliomas.
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- Journal of Neuro-Oncology, 2024, v. 166, n. 1, p. 73, doi. 10.1007/s11060-023-04515-z
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- Publication type:
- Article
Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33784-2
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- Publication type:
- Article
What Animal Cancers teach us about Human Biology.
- Published in:
- Theranostics, 2021, v. 11, n. 14, p. 6682, doi. 10.7150/thno.56623
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- Publication type:
- Article
Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 3, p. 1, doi. 10.1093/jnci/dju502
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- Publication type:
- Article
Adaptive mitochondrial reprogramming and resistance to PI3K therapy.
- Published in:
- 2015
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- Publication type:
- journal article
The effects of PI3K-mediated signalling on glioblastoma cell behaviour.
- Published in:
- Oncogenesis, 2017, v. 6, n. 11, p. 1, doi. 10.1038/s41389-017-0004-8
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- Publication type:
- Article