Works by Siedlak, Sandra L.

Results: 68

The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease.

Published in:

Brain Pathology, 2019, v. 29, n. 4, p. 530, doi. 10.1111/bpa.12691

By:

Wang, Chunyu;
Zhao, Fanpeng;
Shen, Katie;
Wang, Wenzhang;
Siedlak, Sandra L.;
Lee, Hyoung‐gon;
Phelix, Clyde F.;
Perry, George;
Shen, Lu;
Tang, Beisha;
Yan, Riqiang;
Zhu, Xiongwei

Publication type:

Article

Redox metals and oxidative abnormalities in human prion diseases.

Published in:

Acta Neuropathologica, 2005, v. 110, n. 3, p. 232, doi. 10.1007/s00401-005-1034-4

By:

Petersen, Robert B.;
Siedlak, Sandra L.;
Hyoung-gon Lee;
Yong-Sun Kim;
Nunomura, Akihiko;
Tagliavini, Fabrizio;
Ghetti, Bernardino;
Cras, Patrick;
Moreira, Paula I.;
Castellani, Rudy J.;
Guentchev, Marin;
Budka, Herbert;
Ironside, James W.;
Gambetti, Pierluigi;
Smith, Mark A.;
Perry, George

Publication type:

Article

Abortive apoptosis in Alzheimer's disease.

Published in:

Acta Neuropathologica, 2001, v. 101, n. 4, p. 305, doi. 10.1007/s004010100378

By:

Raina, Arun K.;
Hochman, Ayala;
Zhu, Xiongwei;
Rottkamp, Catherine A.;
Nunomura, Akihiko;
Siedlak, Sandra L.;
Boux, Heather;
Castellani, Rudolph J.;
Perry, George;
Smith, Mark A.

Publication type:

Article

Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010116

By:

Song Han;
Nandy, Priya;
Austria, Quillan;
Siedlak, Sandra L.;
Torres, Sandy;
Hisashi Fujioka;
Wenzhang Wang;
Xiongwei Zhu

Publication type:

Article

A Novel Endogenous Indole Protects Rodent Mitochondria and Extends Rotifer Lifespan.

Published in:

PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010206

By:

Poeggeler, Burkhard;
Sambamurti, Kumar;
Siedlak, Sandra L.;
Perry, George;
Smith, Mark A.;
Pappolla, Miguel A.

Publication type:

Article

Cell Cycle Re-Entry and Mitochondrial Defects in Myc-Mediated Hypertrophic Cardiomyopathy and Heart Failure.

Published in:

PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0007172

By:

Hyoung-gon Lee;
Qun Chen;
Wolfram, Julie A.;
Richardson, Sandy L.;
Liner, Anna;
Siedlak, Sandra L.;
Xiongwei Zhu;
Ziats, Nicholas P.;
Fujioka, Hisashi;
Felsher, Dean W.;
Castellani, Rudy J.;
Valencik, Maria L.;
McDonald, John A.;
Hoit, Brian D.;
Lesnefsky, Edward J.;
Smith, Mark A.

Publication type:

Article

Mitochondrial Autophagocytosis in Alzheimer Disease.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A73, doi. 10.1096/fasebj.21.5.a73-c

By:

Perry, George;
Moreira, Paula I.;
Siedlak, Sandra L.;
Santos, Maria S.;
Oliveira, Catarina R.;
Fujioka, Hisashi;
Tabaton, Massimo;
Nunomura, Akihiko;
Aliev, Gjumrakch;
Szweda, Luke I.;
Smith, Mark A.

Publication type:

Article

Widespread distribution of reticulon-3 in various neurodegenerative diseases.

Published in:

Neuropathology, 2010, v. 30, n. 6, p. 574, doi. 10.1111/j.1440-1789.2010.01107.x

By:

Heath, Jonathon E.;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Lee, Hyoung-gon;
Thakur, Akanksha;
Yan, Riqiang;
Perry, George;
Smith, Mark A.;
Castellani, Rudy J.

Publication type:

Article

Redox active iron accumulation in aceruloplasminemia.

Published in:

Neuropathology, 2008, v. 28, n. 5, p. 466, doi. 10.1111/j.1440-1789.2008.00901.x

By:

Gonzalez-Cuyar, Luis F.;
Perry, George;
Miyajima, Hiroaki;
Atwood, Craig S.;
Riveros-Angel, Marcela;
Lyons, Patrick F.;
Siedlak, Sandra L.;
Smith, Mark A.;
Castellani, Rudy J.

Publication type:

Article

Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 21, p. 4118, doi. 10.1093/hmg/ddx299

By:

Wenzhang Wang;
Jun Yin;
Xiaopin Ma;
Fanpeng Zhao;
Siedlak, Sandra L.;
Zhenlian Wang;
Torres, Sandy;
Hisashi Fujioka;
Ying Xu;
Perry, George;
Xiongwei Zhu

Publication type:

Article

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 5, p. 1322, doi. 10.1093/hmg/ddu542

By:

Johnson, William M.;
Yao, Chen;
Siedlak, Sandra L.;
Wang, Wenzhang;
Zhu, Xiongwei;
Caldwell, Guy A.;
Wilson-Delfosse, Amy L.;
Mieyal, John J.;
Chen, Shu G.

Publication type:

Article

Premature centromere division of metaphase chromosomes in peripheral blood lymphocytes of Alzheimer's disease patients: relation to gender and age.

Published in:

2010

By:

Zivkovic, Lada;
Spremo-Potparevic, Biliana;
Plecas-Solarovic, Bosiljka;
Djelic, Ninoslav;
Ocic, Gordana;
Smiljkovic, Predrag;
Siedlak, Sandra L.;
Smith, Mark A.;
Bajic, Vladan

Publication type:

Journal Article

Premature Centromere Division of Metaphase Chromosomes in Peripheral Blood Lymphocytes of Alzheimer's Disease Patients: Relation to Gender and Age.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, v. 65A, n. 12, p. 1269, doi. 10.1093/gerona/glq148

By:

Živković, Lada;
Spremo-Potparević, Biljana;
Plećaš-Solarović, Bosiljka;
Djelić, Ninoslav;
Ocić, Gordana;
Smiljković, Predrag;
Siedlak, Sandra L.;
Smith, Mark A.;
Bajić, Vladan

Publication type:

Article

Overexpression of GRK2 in Alzheimer Disease and in a Chronic Hypoperfusion Rat Model is an Early Marker of Brain Mitochondrial Lesions.

Published in:

Neurotoxicity Research, 2006, v. 10, n. 1, p. 43, doi. 10.1007/BF03033333

By:

Obrenovich, Mark E.;
Smith, Mark A.;
Siedlak, Sandra L.;
Chen, Shu G.;
De la Torre, Jack C.;
Perry, George;
Aliev, Gjumrakch

Publication type:

Article

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease.

Published in:

Scientific Reports, 2016, p. 20352, doi. 10.1038/srep20352

By:

Wang, Chunyu;
Zhang, Fan;
Jiang, Sirui;
Siedlak, Sandra L.;
Shen, Lu;
Perry, George;
Wang, Xinglong;
Tang, Beisha;
Zhu, Xiongwei

Publication type:

Article

Miro1 deficiency in amyotrophic lateral sclerosis.

Published in:

Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00100

By:

Fan Zhang;
Wenzhang Wang;
Siedlak, Sandra L.;
Yingchao Liu;
Jun Liu;
Keji Jiang;
Perry, George;
Xiongwei Zhu;
Xinglong Wang

Publication type:

Article

LRRK2 protein is a component of Lewy bodies.

Published in:

2006

By:

Zhu X;
Siedlak SL;
Smith MA;
Perry G;
Chen SG;
Zhu, Xiongwei;
Siedlak, Sandra L;
Smith, Mark A;
Perry, George;
Chen, Shu G

Publication type:

Letter

Transthyretin and Aβ in Alzheimer's disease

Published in:

2010

By:

Gustaw-Rothenberg, Katarzyna A.;
Friedland, Robert P.;
Dmoszynska, Magdalena;
Siedlak, Sandra L.;
Smith, Mark A.

Publication type:

Abstract

Total antioxidant status in newly diagnosed Alzheimer's patients: Population based study

Published in:

2010

By:

Gustaw-Rothenberg, Katarzyna A.;
Siedlak, Sandra L.;
Perry, George;
Lerner, Alan;
Smith, Mark A.

Publication type:

Abstract

MDA and GSH levels in newly diagnosed Alzheimer's disease patients: A population-based study

Published in:

2010

By:

Gustaw-Rothenberg, Katarzyna A.;
Lerner, Alan;
Perry, George;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Smith, Mark A.

Publication type:

Abstract

Abnormal activation of protein kinase C theta in Alzheimer's disease: Pathological implications

Published in:

2010

By:

Lee, Hyunpil;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Smith, Mark A.;
Lee, Hyoung-gon

Publication type:

Abstract

ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease

Published in:

2010

By:

Bamburg, James R.;
Bernstein, Barbara W.;
Davis, Richard C.;
Goldsbury, Claire;
Maloney, Michael T.;
Marsden, Ian T.;
Minamide, Laurie S.;
Pak, Chi W.;
Perry, George;
Podlisny, Marcia B.;
Selkoe, Dennis J.;
Shaw, Alisa E.;
Siedlak, Sandra L.;
Whiteman, Ineka T.

Publication type:

Abstract

Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation

Published in:

2010

By:

Shenk, Justin C.;
Smith, Mark A.;
Castellani, Rudy J.;
Moreira, Paula;
Aliev, Gjumrakch;
Siedlak, Sandra L.;
Harris, Peggy L.R.;
Sayre, Lawrence;
Szweda, Pamela A.;
Szweda, Luke I.;
Perry, George

Publication type:

Abstract

Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study

Published in:

2009

By:

Gustaw-Rothenberg, Katarzyna;
Siedlak, Sandra L.;
Lee, Hyoung-gon;
Castellani, Rudy J.;
Zhu, Xiongwei;
Perry, George;
Petersen, Robert B.;
Friedland, Robert P.;
Lerner, Alan J.;
Smith, Mark A.

Publication type:

Abstract

Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease

Published in:

2009

By:

Shenk, Justin C.;
Castellani, Rudy J.;
Moreira, Paula;
Aliev, Gjumrakch;
Siedlak, Sandra L.;
Harris, Peggy L.R.;
Sayre, Lawrence;
Szweda, Pamela A.;
Smith, Mark A.;
Perry, George

Publication type:

Abstract

P4-185: Mitochondrial dysfunction in Alzheimer's disease

Published in:

2008

By:

Moreira, Paula I.;
Santos, Maria S.;
Siedlak, Sandra L.;
Harris, Peggy;
Smith, Mark A.;
Aliev, Gjumrakch;
Perry, George;
Oliveira, Catarina R.

Publication type:

Abstract

P4-170: Peroxidative nitrotyrosine formation in Alzheimer's disease

Published in:

2008

By:

Perry, George;
Cash, Adam D.;
Harris, Peggy L.;
Siedlak, Sandra L.;
Smith, Mark A.;
Zhu, Xiongwei

Publication type:

Abstract

P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease

Published in:

2008

By:

Smith, Mark A.;
Garrett, Matthew R.;
Lee, Hyoung-gon;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Perry, George;
Friedland, Robert P.;
Gustaw, Kasia

Publication type:

Abstract

P4-162: LRRK2 in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies

Published in:

2006

By:

Smith, Mark A.;
Zhu, Xiongwei;
Babar, Asim;
Siedlak, Sandra L.;
Yang, Qiwei;
Ito, Genta;
Iwatsubo, Takeshi;
Perry, George;
Chen, Shu G.

Publication type:

Abstract

O4-02-08: Mitochondrial autophagocytosis in Alzheimer disease

Published in:

2006

By:

Moreira, Paula I.;
Siedlak, Sandra L.;
Santos, Maria S.;
Oliveira, Catarina R.;
Fujioka, Hisashi;
Tabaton, Massimo;
Nunomura, Akihiko;
Aliev, Gjumrakch;
Szweda, Luke I.;
Zhu, Xiongwei;
Smith, Mark A.;
Perry, George

Publication type:

Abstract

P4-162: LRRK2 in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies

Published in:

2006

By:

Smith, Mark A.;
Zhu, Xiongwei;
Babar, Asim;
Siedlak, Sandra L.;
Yang, Qiwei;
Ito, Genta;
Iwatsubo, Takeshi;
Perry, George;
Chen, Shu G.

Publication type:

Abstract

O4-02-08: Mitochondrial autophagocytosis in Alzheimer disease

Published in:

2006

By:

Moreira, Paula I.;
Siedlak, Sandra L.;
Santos, Maria S.;
Oliveira, Catarina R.;
Fujioka, Hisashi;
Tabaton, Massimo;
Nunomura, Akihiko;
Aliev, Gjumrakch;
Szweda, Luke I.;
Zhu, Xiongwei;
Smith, Mark A.;
Perry, George

Publication type:

Abstract

Telomeres and telomerase in Alzheimer’s disease: Epiphenomena or a new focus for therapeutic strategy?

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2006, v. 2, n. 3, p. 164, doi. 10.1016/j.jalz.2006.03.001

By:

Franco, Sonia;
Blasco, Maria A.;
Siedlak, Sandra L.;
Harris, Peggy L.R.;
Moreira, Paula I.;
Perry, George;
Smith, Mark A.

Publication type:

Article

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.

Published in:

Redox Report, 2010, v. 15, n. 4, p. 161, doi. 10.1179/174329210X12650506623645

By:

Bonda, David J.;
Mailankot, Maneesh;
Stone, Jeremy G.;
Garrett, Matthew R.;
Staniszewska, Magdalena;
Castellani, Rudy J.;
Siedlak, Sandra L.;
Xiongwei Zhu;
Hyoung-gon Lee;
Perry, George;
Nagaraj, Ram H.;
Smith, Mark A.

Publication type:

Article

Hydroxynonenal-Generated Crosslinking Fluorophore and Mitochondria-derived Lipoic Acid Accumulation in Alzheimer Disease Reveal a Dichotomy of Protein Turnover.

Published in:

2010

By:

Castellani, R. J.;
Moreira, Paula;
Aliev, Gjumrakch;
Shenk, Justin C.;
Siedlak, Sandra L.;
Harris, Peggy L. R.;
Sayre, Lawrence M.;
Szweda, Luke I.;
Xiongwei Zhu;
Smith, Mark A.;
Perry, George;
Szweda, Pamela A.

Publication type:

Abstract

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.

Published in:

Molecular Neurodegeneration, 2018, v. 13, p. 1, doi. 10.1186/s13024-018-0238-8

By:

Jiang, Sirui;
Nandy, Priya;
Wang, Wenzhang;
Ma, Xiaopin;
Hsia, Jeffrey;
Wang, Chunyu;
Wang, Zhenlian;
Niu, Mengyue;
Siedlak, Sandra L.;
Torres, Sandy;
Fujioka, Hisashi;
Xu, Ying;
Lee, Hyoung-gon;
Perry, George;
Liu, Jun;
Zhu, Xiongwei

Publication type:

Article

Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease.

Published in:

Journal of Neurochemistry, 2006, v. 99, n. 5, p. 1377, doi. 10.1111/j.1471-4159.2006.04174.x

By:

Mei, Matthew;
Bo Su;
Harrison, Kristen;
Chao, Mark;
Siedlak, Sandra L.;
Previll, Laura A.;
Jackson, LaMia;
Cai, Dan X.;
Xiongwei Zhu

Publication type:

Article

Neuroprotective properties of Bcl-w in Alzheimer disease.

Published in:

Journal of Neurochemistry, 2004, v. 89, n. 5, p. 1233, doi. 10.1111/j.1471-4159.2004.02416.x

By:

Zhu, Xiongwei;
Wang, Yang;
Ogawa, Osamu;
Lee, Hyoung-Gon;
Raina, Arun K.;
Siedlak, Sandra L.;
Harris, Peggy L. R.;
Fujioka, Hisashi;
Shimohama, Shun;
Tabaton, Massimo;
Atwood, Craig S.;
Petersen, Robert B.;
Perry, George;
Smith, Mark A.

Publication type:

Article

Distribution, levels, and activation of MEK1 in Alzheimer's disease.

Published in:

Journal of Neurochemistry, 2003, v. 86, n. 1, p. 136, doi. 10.1046/j.1471-4159.2003.01820.x

By:

Zhu, Xiongwei;
Sun, Zheng;
Lee, Hyoung-gon;
Siedlak, Sandra L.;
Perry, George;
Smith, Mark A.

Publication type:

Article

In Alzheimer's Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of τ Induced by 4-Hydroxy-2-Nonenal Modification.

Published in:

Journal of Neurochemistry, 2000, v. 75, n. 3, p. 1234, doi. 10.1046/j.1471-4159.2000.0751234.x

By:

Takeda, Atsushi;
Smith, Mark A.;
Avilá, Jesus;
Nunomura, Akihiko;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Perry, George;
Sayre, Lawrence M.

Publication type:

Article

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress.

Published in:

Journal of Neurochemistry, 1998, v. 70, n. 5, p. 2212, doi. 10.1046/j.1471-4159.1998.70052212.x

By:

Smith, Mark A.;
Hirai, Keisuke;
Hsiao, Karen;
Pappolla, Miguel A.;
Harris, Peggy L. R.;
Siedlak, Sandra L.;
Tabaton, Massimo;
Perry, George

Publication type:

Article

Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 7, p. 5157, doi. 10.1007/s12035-018-1431-z

By:

Zhao, Fanpeng;
Siedlak, Sandra L.;
Torres, Sandy L.;
Xu, Qian;
Tang, Beisha;
Zhu, Xiongwei

Publication type:

Article

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.

Published in:

Journal of Neurochemistry, 2014, v. 128, n. 1, p. 162, doi. 10.1111/jnc.12380

By:

Bonda, David J.;
Stone, Jeremy G.;
Torres, Sandy L.;
Siedlak, Sandra L.;
Perry, George;
Kryscio, Richard;
Jicha, Gregory;
Casadesus, Gemma;
Smith, Mark A.;
Zhu, Xiongwei;
Lee, Hyoung‐gon

Publication type:

Article

Antigen–antibody dissociation in Alzheimer disease: a novel approach to diagnosis.

Published in:

Journal of Neurochemistry, 2008, v. 106, n. 3, p. 1350, doi. 10.1111/j.1471-4159.2008.05477.x

By:

Gustaw, Katarzyna A.;
Garrett, Matthew R.;
Lee, Hyoung-gon;
Castellani, Rudy J.;
Zagorski, Michael G.;
Prakasam, Annamalai;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Perry, George;
Petersen, Robert B.;
Friedland, Robert P.;
Smith, Mark A.

Publication type:

Article

Posttranslational modifications of α-tubulin in alzheimer disease.

Published in:

Translational Neurodegeneration, 2015, v. 4, n. 1, p. 4, doi. 10.1186/s40035-015-0030-4

By:

Fan Zhang;
Bo Su;
Chunyu Wang;
Siedlak, Sandra L.;
Mondragon-Rodriguez, Siddhartha;
Hyoung-gon Lee;
Xinglong Wang;
Perry, George;
Xiongwei Zhu

Publication type:

Article

Correction: Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation.

Published in:

2016

By:

Blair, Jeffrey A.;
Wang, Chunyu;
Hernandez, Damarys;
Siedlak, Sandra L.;
Rodgers, Mark S.;
Achar, Rohan K.;
Fahmy, Lara M.;
Torres, Sandy L.;
Petersen, Robert B.;
Zhu, Xiongwei;
Casadesus, Gemma;
Lee, Hyoung-gon

Publication type:

Correction Notice

Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation.

Published in:

2016

By:

Blair, Jeffrey A.;
Wang, Chunyu;
Hernandez, Damarys;
Siedlak, Sandra L.;
Rodgers, Mark S.;
Achar, Rojan K.;
Fahmy, Lara M.;
Torres, Sandy L.;
Petersen, Robert B.;
Zhu, Xiongwei;
Casadesus, Gemma;
Lee, Hyoung-gon

Publication type:

Case Study

Antimicrobial peptide beta-defensin-1 expression is upregulated in Alzheimer's brain.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-127

By:

Williams, Wesley M.;
Torres, Sandy;
Siedlak, Sandra L.;
Castellani, Rudy J.;
Perry, George;
Smith, Mark A.;
Xiongwei Zhu

Publication type:

Article

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain.

Published in:

2013

By:

Williams, Wesley M;
Torres, Sandy;
Siedlak, Sandra L;
Castellani, Rudy J;
Perry, George;
Smith, Mark A;
Zhu, Xiongwei

Publication type:

journal article

Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.

Published in:

Free Radical Research, 2009, v. 43, n. 2, p. 156, doi. 10.1080/10715760802644694

By:

Siedlak, Sandra L.;
Casadesus, Gemma;
Webber, Kate M.;
Pappolla, Miguel A.;
Atwood, Craig S.;
Smith, Mark A.;
Perry, George

Publication type:

Article