Works by Sica, Filomena

Results: 34

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 7, p. e79, doi. 10.1093/nar/gkt028

By:

Stelitano, Valentina;
Brandt, Annegret;
Fernicola, Silvia;
Franceschini, Stefano;
Giardina, Giorgio;
Pica, Andrea;
Rinaldo, Serena;
Sica, Filomena;
Cutruzzolà, Francesca

Publication type:

Article

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 16, p. 8119, doi. 10.1093/nar/gks512

By:

Russo Krauss, Irene;
Merlino, Antonello;
Randazzo, Antonio;
Novellino, Ettore;
Mazzarella, Lelio;
Sica, Filomena

Publication type:

Article

Thrombin–aptamer recognition: a revealed ambiguity.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 17, p. 7858, doi. 10.1093/nar/gkr522

By:

Russo Krauss, Irene;
Merlino, Antonello;
Giancola, Concetta;
Randazzo, Antonio;
Mazzarella, Lelio;
Sica, Filomena

Publication type:

Article

The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative.

Published in:

Proteins, 2003, v. 52, n. 2, p. 263, doi. 10.1002/prot.10407

By:

Filomena Sica;
Anna Di Fiore

Publication type:

Article

Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer.

Published in:

FEBS Journal, 2013, v. 280, n. 24, p. 6581, doi. 10.1111/febs.12561

By:

Pica, Andrea;
Russo Krauss, Irene;
Merlino, Antonello;
Nagatoishi, Satoru;
Sugimoto, Naoki;
Sica, Filomena

Publication type:

Article

A novel ErbB2 epitope targeted by human antitumor immunoagents.

Published in:

FEBS Journal, 2011, v. 278, n. 7, p. 1156, doi. 10.1111/j.1742-4658.2011.08041.x

By:

Troise, Fulvia;
Monti, Maria;
Merlino, Antonello;
Cozzolino, Flora;
Fedele, Carmine;
Russo Krauss, Irene;
Sica, Filomena;
Pucci, Piero;
D'Alessio, Giuseppe;
De Lorenzo, Claudia

Publication type:

Article

Understanding the binding properties of an unusual metal-binding protein − a study of bacterial frataxin.

Published in:

FEBS Journal, 2007, v. 274, n. 16, p. 4199, doi. 10.1111/j.1742-4658.2007.05946.x

By:

Pastore, Chiara;
Franzese, Marisa;
Sica, Filomena;
Temussi, Pierandrea;
Pastore, Annalisa

Publication type:

Article

Aptamers: Functional-Structural Studies and Biomedical Applications 2.0.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4279, doi. 10.3390/ijms25084279

By:

Troisi, Romualdo;
Sica, Filomena

Publication type:

Article

Structural Insights into Protein–Aptamer Recognitions Emerged from Experimental and Computational Studies.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 22, p. 16318, doi. 10.3390/ijms242216318

By:

Troisi, Romualdo;
Balasco, Nicole;
Autiero, Ida;
Vitagliano, Luigi;
Sica, Filomena

Publication type:

Article

Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8781, doi. 10.3390/ijms23158781

By:

Culurciello, Rosanna;
Bosso, Andrea;
Troisi, Romualdo;
Barrella, Valentina;
Di Nardo, Ilaria;
Borriello, Margherita;
Gaglione, Rosa;
Pistorio, Valeria;
Aceto, Serena;
Cafaro, Valeria;
Notomista, Eugenio;
Sica, Filomena;
Arciello, Angela;
Pizzo, Elio

Publication type:

Article

Aptamers: Functional-Structural Studies and Biomedical Applications.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4796, doi. 10.3390/ijms23094796

By:

Troisi, Romualdo;
Sica, Filomena

Publication type:

Article

Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10803, doi. 10.3390/ijms221910803

By:

Troisi, Romualdo;
Balasco, Nicole;
Autiero, Ida;
Vitagliano, Luigi;
Sica, Filomena

Publication type:

Article

Artificial Intelligence in Aptamer–Target Binding Prediction.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3605, doi. 10.3390/ijms22073605

By:

Chen, Zihao;
Hu, Long;
Zhang, Bao-Ting;
Lu, Aiping;
Wang, Yaofeng;
Yu, Yuanyuan;
Zhang, Ge;
Sica, Filomena;
Troisi, Romualdo

Publication type:

Article

An Overview of Biological Macromolecule Crystallization.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 6, p. 11643, doi. 10.3390/ijms140611643

By:

Krauss, Irene Russo;
Merlino, Antonello;
Vergara, Alessandro;
Sica, Filomena

Publication type:

Article

Increasing the X-ray Diffraction Power of Protein Crystals by Dehydration: The Case of Bovine Serum Albumin and a Survey of Literature Data.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 3, p. 3782, doi. 10.3390/ijms13033782

By:

Krauss, Irene Russo;
Sica, Filomena;
Mattia, Carlo Andrea;
Merlino, Antonello

Publication type:

Article

Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis.

Published in:

International Journal of Molecular Sciences, 2011, v. 12, n. 9, p. 6312, doi. 10.3390/ijms12096312

By:

Merlino, Antonello;
Krauss, Irene Russo;
Albino, Antonella;
Pica, Andrea;
Vergara, Alessandro;
Masullo, Mariorosario;
De Vendittis, Emmanuele;
Sica, Filomena

Publication type:

Article

Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.

Published in:

Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 1, p. 50, doi. 10.1002/pro.6

By:

Merlino, Antonello;
Avella, Giovanna;
Di Gaetano, Sonia;
Arciello, Angela;
Piccoli, Renata;
Mazzarella, Lelio;
Sica, Filomena

Publication type:

Article

The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer.

Published in:

FEBS Letters, 2013, v. 587, n. 23, p. 3755, doi. 10.1016/j.febslet.2013.10.003

By:

Sica, Filomena;
Pica, Andrea;
Merlino, Antonello;
Russo Krauss, Irene;
Ercole, Carmine;
Picone, Delia

Publication type:

Article

Structural study of a single-point mutant of Sulfolobus solfataricus alcohol dehydrogenase with enhanced activity

Published in:

FEBS Letters, 2003, v. 539, n. 1-3, p. 14, doi. 10.1016/S0014-5793(03)00173-X

By:

Esposito, Luciana;
Bruno, Ilaria;
Sica, Filomena;
Raia, Carlo Antonio;
Giordano, Antonietta;
Rossi, Mosè;
Mazzarella, Lelio;
Zagari, Adriana

Publication type:

Article

Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2′,5′)adenosine.

Published in:

Protein Science: A Publication of the Protein Society, 1998, v. 7, n. 8, p. 1691, doi. 10.1002/pro.5560070804

By:

Vitagliano, Luigi;
Adinolfi, Salvatore;
Riccio, Antonio;
Sica, Filomena;
Zagari, Adriana;
Mazzarella, Lelio

Publication type:

Article

Structure–Activity Relationship Study of a Potent α‐Thrombin Binding Aptamer Incorporating Hexitol Nucleotides.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 43, p. 9589, doi. 10.1002/chem.202001504

By:

De Fenza, Maria;
Eremeeva, Elena;
Troisi, Romualdo;
Yang, Hui;
Esposito, Anna;
Sica, Filomena;
Herdewijn, Piet;
D'Alonzo, Daniele;
Guaragna, Annalisa

Publication type:

Article

Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent.

Published in:

International Journal of Cancer, 2008, v. 123, n. 11, p. 2684, doi. 10.1002/ijc.23791

By:

Mancini, Aldo;
Borrelli, Antonella;
Schiattarella, Antonella;
Aloj, Luigi;
Aurilio, Michela;
Morelli, Franco;
Pica, Alessandra;
Occhiello, Antonella;
Lorizio, Roberto;
Mancini, Roberto;
Sica, Alessandro;
Mazzarella, Lelio;
Sica, Filomena;
Grieco, Paolo;
Novellino, Ettore;
Pagnozzi, Daniela;
Pucci, Piero;
Rommelaere, Jean

Publication type:

Article

Combined crystallographic and spectroscopic analysis of Trematomus bernacchii hemoglobin highlights analogies and differences in the peculiar oxidation pathway of Antarctic fish hemoglobins.

Published in:

Biopolymers, 2009, v. 91, n. 12, p. 1117, doi. 10.1002/bip.21206

By:

Merlino, Antonello;
Vitagliano, Luigi;
Howes, Barry D.;
Verde, Cinzia;
di Prisco, Guido;
Smulevich, Giulietta;
Sica, Filomena;
Vergara, Alessandro

Publication type:

Article

Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants.

Published in:

Biopolymers, 2009, v. 91, n. 12, p. 1029, doi. 10.1002/bip.21183

By:

Merlino, Antonello;
Krauss, Irene Russo;
Perillo, Margherita;
Mattia, Carlo Andrea;
Ercole, Carmine;
Picone, Delia;
Vergara, Alessandro;
Sica, Filomena

Publication type:

Article

Introduction.

Published in:

Biopolymers, 2009, v. 91, n. 12, p. 975, doi. 10.1002/bip.21252

By:

Smulevich, Giulietta;
Sica, Filomena

Publication type:

Article

Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer.

Published in:

Biopolymers, 2004, v. 73, n. 6, p. 689, doi. 10.1002/bip.20016

By:

Merlino, Antonello;
Vitagliano, Luigi;
Sica, Filomena;
Zagari, Adriana;
Mazzarella, Lelio

Publication type:

Article

Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 16, p. 8880, doi. 10.1093/nar/gkad634

By:

Troisi, Romualdo;
Napolitano, Valeria;
Rossitto, Emanuele;
Osman, Waleed;
Nagano, Masanobu;
Wakui, Koji;
Popowicz, Grzegorz M;
Yoshimoto, Keitaro;
Sica, Filomena

Publication type:

Article

Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 22, p. 12177, doi. 10.1093/nar/gky990

By:

Troisi, Romualdo;
Napolitano, Valeria;
Spiridonova, Vera;
Russo Krauss, Irene;
Sica, Filomena

Publication type:

Article

Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 1, p. 461, doi. 10.1093/nar/gkw1113

By:

Pica, Andrea;
Krauss, Irene Russo;
Parente, Valeria;
Hisae Tateishi-Karimata;
Satoru Nagatoishi;
Kouhei Tsumoto;
Naoki Sugimoto;
Sica, Filomena

Publication type:

Article

Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 2, p. 983, doi. 10.1093/nar/gkv1384

By:

Krauss, Irene Russo;
Spiridonova, Vera;
Pica, Andrea;
Napolitano, Valeria;
Sica, Filomena

Publication type:

Article

The crystal structure of Sulfolobus solfataricus elongation factor 1a in complex with GDP reveals novel features in nucleotide binding and exchange.

Published in:

EMBO Journal, 2001, v. 20, n. 19, p. 5305, doi. 10.1093/emboj/20.19.5305

By:

Vitagliano, Luigi;
Masuiio, Mariorosario;
Sica, Filomena;
Zagari, Adriana;
Bocchini, Vincenzo

Publication type:

Article

High yield purification and first structural characterization of the full‐length bacterial toxin CNF1.

Published in:

Biotechnology Progress, 2018, v. 34, n. 1, p. 150, doi. 10.1002/btpr.2574

By:

Colarusso, Andrea;
Caterino, Marco;
Fabbri, Alessia;
Fiorentini, Carla;
Vergara, Alessandro;
Sica, Filomena;
Parrilli, Ermenegilda;
Tutino, Maria Luisa

Publication type:

Article

Protonation of histidine 55 affects the oxygen access to heme in the alpha chain of the hemoglobin from the Antarctic fish Trematomus bernacchii.

Published in:

IUBMB Life, 2011, v. 63, n. 3, p. 175, doi. 10.1002/iub.436

By:

Boechi, Leonardo;
Martì, Marcelo A.;
Vergara, Alessandro;
Sica, Filomena;
Mazzarella, Lelio;
Estrin, Dario A.;
Merlino, Antonello

Publication type:

Article

Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 6, p. 2199, doi. 10.1080/07391102.2020.1746693

By:

Troisi, Romualdo;
Balasco, Nicole;
Vitagliano, Luigi;
Sica, Filomena

Publication type:

Article