Works by Sibley, L. David

Results: 76

Modulation of innate immunity by Toxoplasma gondii virulence effectors.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 11, p. 766, doi. 10.1038/nrmicro2858

By:

Hunter, Christopher A.;
Sibley, L. David

Publication type:

Article

Correction: Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii.

Published in:

2015

By:

Steinfeldt, Tobias;
Könen-Waisman, Stephanie;
Tong, Lan;
Pawlowski, Nikolaus;
Lamkemeyer, Tobias;
Sibley, L. David;
Hunn, Julia P.;
Howard, Jonathan C.

Publication type:

Correction Notice

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii.

Published in:

PLoS Biology, 2010, v. 8, n. 12, p. 1, doi. 10.1371/journal.pbio.1000576

By:

Steinfeldt, Tobias;
Könen-Waisman, Stephanie;
Lan Tong;
Pawlowski, Nikolaus;
Lamkemeyer, Tobias;
Sibley, L. David;
Hunn, Julia P.;
Howard, Jonathan C.

Publication type:

Article

Comparative Genomic and Phylogenetic Analyses of Calcium ATPases and Calcium-Regulated Proteins in the Apicomplexa.

Published in:

Molecular Biology & Evolution, 2006, v. 23, n. 8, p. 1613, doi. 10.1093/molbev/msl026

By:

Nagamune, Kisaburo;
Sibley, L. David

Publication type:

Article

Structural Evidence for Actin-like Filaments in Toxoplasma gondii Using High-Resolution Low-Voltage Field Emission Scanning Electron Microscopy.

Published in:

Microscopy & Microanalysis, 2003, v. 9, n. 4, p. 330, doi. 10.1017/s1431927603030095

By:

Heide Schatten;
L. David Sibley;
Hans Ris

Publication type:

Article

Phagosome acidification blocked by intracellular Toxoplasma gondii.

Published in:

Nature, 1985, v. 315, n. 6018, p. 416, doi. 10.1038/315416a0

By:

Sibley, L. David;
Weidner, Earl;
Krahenbuhl, James L.

Publication type:

Article

Toxoplasma gondii: Perfecting an Intracellular Life Style.

Published in:

Traffic, 2003, v. 4, n. 9, p. 581, doi. 10.1034/j.1600-0854.2003.00117.x

By:

Sibley, L. David

Publication type:

Article

Cell Invasion by Un-Palatable Parasites.

Published in:

Traffic, 2000, v. 1, n. 2, p. 100, doi. 10.1034/j.1600-0854.2000.010202.x

By:

Sibley, L. David;
Andrews, Norma W.

Publication type:

Article

Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii.

Published in:

Nature, 2008, v. 451, n. 7175, p. 207, doi. 10.1038/nature06478

By:

Nagamune, Kisaburo;
Hicks, Leslie M.;
Fux, Blima;
Brossier, Fabien;
Chini, Eduardo N.;
Sibley, L. David

Publication type:

Article

Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii.

Published in:

Molecular Microbiology, 1999, v. 31, n. 2, p. 421, doi. 10.1046/j.1365-2958.1999.01174.x

By:

Carruthers, Vern B;
Sibley, L. David

Publication type:

Article

Participation of myosin in gliding motility and host cell invasion by Toxoplasma gondii.

Published in:

Molecular Microbiology, 1997, v. 26, n. 1, p. 163, doi. 10.1046/j.1365-2958.1997.5671913.x

By:

Dobrowolski, Janice M.;
Carruthers, Vern B.;
Sibley, L. David

Publication type:

Article

Genetic divergence of Toxoplasma gondii strains associated with ocular toxoplasmosis, Brazil.

Published in:

2006

By:

Khan, Asis;
Jordan, Catherine;
Muccioli, Cristina;
Vallochi, Adriana L.;
Rizzo, Luiz V.;
Belfort Jr, Rubens;
Vitor, Ricardo W. A.;
Silveira, Claudio;
Sibley, L. David;
Belfort, Rubens Jr

Publication type:

journal article

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 9, p. 2980, doi. 10.1093/nar/gki604

By:

Khan, Asis;
Taylor, Sonya;
Su, Chunlei;
Mackey, Aaron J.;
Boyle, Jon;
Cole, Robert;
Glover, Darius;
Tang, Keliang;
Paulsen, Ian T.;
Berriman, Matt;
Boothroyd, John C.;
Pfefferkorn, Elmer R.;
Dubey, J. P.;
Ajioka, James W.;
Roos, David S.;
Wootton, John C.;
Sibley, L. David

Publication type:

Article

ApiEST‐DB: analyzing clustered EST data of the apicomplexan parasites.

Published in:

Nucleic Acids Research, 2004, v. 32, n. suppl 1, p. d326

By:

Li, Li;
Crabtree, Jonathan;
Fischer, Steve;
Pinney, Deborah;
Stoeckert, Christian J.;
Sibley, L. David;
Roos, David S.

Publication type:

Article

Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28108-y

By:

Radke, Joshua B.;
Melillo, Bruno;
Mittal, Payal;
Sharma, Manmohan;
Sharma, Amit;
Fu, Yong;
Uddin, Taher;
Gonse, Arthur;
Comer, Eamon;
Schreiber, Stuart L.;
Gupta, Anil K.;
Chatterjee, Arnab K.;
Sibley, L. David

Publication type:

Article

Publisher Correction: Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins.

Published in:

2021

By:

Wang, Xiangli;
Fu, Yong;
Beatty, Wandy L.;
Ma, Meisheng;
Brown, Alan;
Sibley, L. David;
Zhang, Rui

Publication type:

Correction Notice

Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23351-1

By:

Wang, Xiangli;
Fu, Yong;
Beatty, Wandy L.;
Ma, Meisheng;
Brown, Alan;
Sibley, David L.;
Zhang, Rui

Publication type:

Article

Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23351-1

By:

Wang, Xiangli;
Fu, Yong;
Beatty, Wandy L.;
Ma, Meisheng;
Brown, Alan;
David Sibley, L.;
Zhang, Rui

Publication type:

Article

Geographic Separation of Domestic and Wild Strains of Toxoplasma gondii in French Guiana Correlates with a Monomorphic Version of Chromosome1a.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003182

By:

Khan, Asis;
Ajzenberg, Daniel;
Mercier, Aurélien;
Demar, Magalie;
Simon, Stéphane;
Dardé, Marie Laure;
Wang, Qiuling;
Verma, Shiv Kumar;
Rosenthal, Benjamin M.;
Dubey, Jitender P.;
Sibley, L. David

Publication type:

Article

Geographic Separation of Domestic and Wild Strains of Toxoplasma gondii in French Guiana Correlates with a Monomorphic Version of Chromosome1a.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003182

By:

Khan, Asis;
Ajzenberg, Daniel;
Mercier, Aurélien;
Demar, Magalie;
Simon, Stéphane;
Dardé, Marie Laure;
Wang, Qiuling;
Verma, Shiv Kumar;
Rosenthal, Benjamin M.;
Dubey, Jitender P.;
Sibley, L. David

Publication type:

Article

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.

Published in:

PLoS Genetics, 2015, v. 11, n. 8, p. 1, doi. 10.1371/journal.pgen.1005434

By:

Behnke, Michael S.;
Khan, Asis;
Lauron, Elvin J.;
Jimah, John R.;
Wang, Qiuling;
Tolia, Niraj H.;
Sibley, L. David

Publication type:

Article

Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice.

Published in:

PLoS Genetics, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.pgen.1000404

By:

Khan, Asis;
Taylor, Sonya;
Ajioka, James W.;
Rosenthal, Benjamin M.;
Sibley, L. David

Publication type:

Article

Phagocytized Intracellular Microsporidian Blocks Phagosome Acidification and Phagosome-Lysosome Fusion.

Published in:

Journal of Eukaryotic Microbiology, 1985, v. 32, n. 2, p. 311, doi. 10.1111/j.1550-7408.1985.tb03056.x

By:

Weidner, Earl;
Sibley, L. David

Publication type:

Article

Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii.

Published in:

PLoS Pathogens, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.ppat.1006379

By:

Long, Shaojun;
Brown, Kevin M.;
Drewry, Lisa L.;
Anthony, Bryan;
Phan, Isabelle Q. H.;
Sibley, L. David

Publication type:

Article

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73137

By:

Rinkenberger, Nicholas;
Abrams, Michael E.;
Matta, Sumit K.;
Schoggins, John W.;
Alto, Neal M.;
Sibley, L. David

Publication type:

Article

Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.73011

By:

Yong Fu;
Brown, Kevin M.;
Jones, Nathaniel G.;
Moreno, Silvia N. J.;
Sibley, L. David

Publication type:

Article

Molecular Partitioning during Host Cell Penetration byToxoplasma gondii.

Published in:

Traffic, 2004, v. 5, n. 11, p. 855, doi. 10.1111/j.1600-0854.2004.00228.x

By:

Charron, Audra J.;
Sibley, L. David

Publication type:

Article

The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36571-4

By:

Wan, Wenyan;
Dong, Hui;
Lai, De-Hua;
Yang, Jiong;
He, Kai;
Tang, Xiaoyan;
Liu, Qun;
Hide, Geoff;
Zhu, Xing-Quan;
Sibley, L. David;
Lun, Zhao-Rong;
Long, Shaojun

Publication type:

Article

The protein phosphatase 2A holoenzyme is a key regulator of starch metabolism and bradyzoite differentiation in Toxoplasma gondii.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35267-5

By:

Wang, Jin-Lei;
Li, Ting-Ting;
Elsheikha, Hany M.;
Liang, Qin-Li;
Zhang, Zhi-Wei;
Wang, Meng;
Sibley, L. David;
Zhu, Xing-Quan

Publication type:

Article

The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31720-7

By:

Huang, Zhou;
Liu, Hejun;
Nix, Jay;
Xu, Rui;
Knoverek, Catherine R.;
Bowman, Gregory R.;
Amarasinghe, Gaya K.;
Sibley, L. David

Publication type:

Article

Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.

Published in:

Gut Microbes, 2024, v. 16, n. 1, p. 1, doi. 10.1080/19490976.2023.2297897

By:

Greigert, Valentin;
Saraav, Iti;
Son, Juhee;
Yinxing Zhu;
Dayao, Denise;
Antia, Avan;
Tzipori, Saul;
Witola, William H.;
Stappenbeck, Thaddeus S.;
Siyuan Ding;
Sibley, L. David

Publication type:

Article

Plants, endosymbionts and parasites.

Published in:

Communicative & Integrative Biology, 2008, v. 1, n. 1, p. 62, doi. 10.4161/cib.1.1.6106

By:

Nagamune, Kisaburo;
Xiong, Liming;
Chini, Eduardo;
Sibley, L. David

Publication type:

Article

Transepithelial migration ofToxoplasma gondiiinvolves an interaction of intercellular adhesion molecule 1 (ICAM-1) with the parasite adhesin MIC2.

Published in:

Cellular Microbiology, 2005, v. 7, n. 4, p. 561, doi. 10.1111/j.1462-5822.2005.00486.x

By:

Barragan, Antonio;
Brossier, Fabien;
Sibley, L. David

Publication type:

Article

Secretion of micronemal proteins is associated with toxoplasma invasion of host cells.

Published in:

Cellular Microbiology, 1999, v. 1, n. 3, p. 225, doi. 10.1046/j.1462-5822.1999.00023.x

By:

Carruthers, Vern B.;
Giddings, Olivia K.;
Sibley, L. David

Publication type:

Article

Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44696-3

By:

Xu, Rui;
Beatty, Wandy L.;
Greigert, Valentin;
Witola, William H.;
Sibley, L. David

Publication type:

Article

Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44696-3

By:

Xu, Rui;
Beatty, Wandy L.;
Greigert, Valentin;
Witola, William H.;
Sibley, L. David

Publication type:

Article

The secreted kinase ROP18 defends Toxoplasma's border.

Published in:

BioEssays, 2011, v. 33, n. 9, p. 693, doi. 10.1002/bies.201100054

By:

Fentress, Sarah J.;
Sibley, L. David

Publication type:

Article

REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1309-7

By:

Shaik, Jahangheer S.;
Khan, Asis;
Beverley, Stephen M.;
Sibley, L. David

Publication type:

Article

NextGen sequencing reveals short double crossovers contribute disproportionately to genetic diversity in Toxoplasma gondii.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 3231, doi. 10.1186/1471-2164-15-1168

By:

Khan, Asis;
Shaik, Jahangheer S.;
Behnke, Michael;
Qiuling Wang;
Dubey, J. P.;
Lorenzi, Hernan A.;
Ajioka, James W.;
Rosenthal, Benjamin M.;
Sibley, L. David

Publication type:

Article

Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-350

By:

Behnke, Michael S.;
Zhang, Tiange P.;
Dubey, Jitender P.;
Sibley, L. David

Publication type:

Article

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii.

Published in:

PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004047

By:

Dupont, Christopher D.;
Christian, David A.;
Selleck, Elizabeth M.;
Pepper, Marion;
Leney-Greene, Michael;
Harms Pritchard, Gretchen;
Koshy, Anita A.;
Wagage, Sagie;
Reuter, Morgan A.;
Sibley, L. David;
Betts, Michael R.;
Hunter, Christopher A.

Publication type:

Article

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii.

Published in:

PLoS Pathogens, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.ppat.1003320

By:

Selleck, Elizabeth M.;
Fentress, Sarah J.;
Beatty, Wandy L.;
Degrandi, Daniel;
Pfeffer, Klaus;
Virgin IV, Herbert W.;
MacMicking, John D.;
Sibley, L. David

Publication type:

Article

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18.

Published in:

PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1002992

By:

Behnke, Michael S.;
Fentress, Sarah J.;
Mashayekhi, Mona;
Li, Lucy X.;
Taylor, Gregory A.;
Sibley, L. David

Publication type:

Article

Evolutionarily Divergent, Unstable Filamentous Actin Is Essential for Gliding Motility in Apicomplexan Parasites.

Published in:

PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002280

By:

Skillman, Kristen M.;
Diraviyam, Karthikeyan;
Khan, Asis;
Tang, Keliang;
Sept, David;
Sibley, L. David

Publication type:

Article

Rhomboid 4 (ROM4) Affects the Processing of Surface Adhesins and Facilitates Host Cell Invasion by Toxoplasma gondii.

Published in:

PLoS Pathogens, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.ppat.1000858

By:

Buguliskis, Jeffrey S.;
Brossier, Fabien;
Shuman, Joel;
Sibley, L. David

Publication type:

Article

Virulent strains of Toxoplasma gondii comprise a single clonal lineage.

Published in:

Nature, 1992, v. 359, n. 6390, p. 82, doi. 10.1038/359082a0

By:

Sibley, L. David;
Boothroyd, John C.

Publication type:

Article

Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole.

Published in:

Molecular Microbiology, 2010, v. 76, n. 6, p. 1358, doi. 10.1111/j.1365-2958.2010.07165.x

By:

Miranda, Kildare;
Pace, Douglas A.;
Cintron, Roxana;
Rodrigues, Juliany C. F.;
Fang, Jianmin;
Smith, Alyssa;
Rohloff, Peter;
Coelho, Elvis;
De Haas, Felix;
De Souza, Wanderley;
Coppens, Isabelle;
Sibley, L. David;
Moreno, Silvia N. J.

Publication type:

Article

The unusual dynamics of parasite actin result from isodesmic polymerization.

Published in:

Nature Communications, 2013, v. 4, n. 8, p. 2285, doi. 10.1038/ncomms3285

By:

Skillman, Kristen M.;
Ma, Christopher I.;
Fremont, Daved H.;
Diraviyam, Karthikeyan;
Cooper, John A.;
Sept, David;
Sibley, L. David

Publication type:

Article

Actin-like protein 1 (ALP1) is a component of dynamic, high molecular weight complexes in Toxoplasma gondii.

Published in:

Cytoskeleton, 2010, v. 67, n. 1, p. 23, doi. 10.1002/cm.20414

By:

Gordon, Jennifer L.;
Buguliskis, Jeffrey S.;
Buske, Paul J.;
Sibley, L. David

Publication type:

Article

Synthesis of Chondramide A Analogues with Modified β-Tyrosine and Their Biological Evaluation.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 47, p. 13349, doi. 10.1002/chem.201101978

By:

Zhdanko, Alexander;
Schmauder, Anke;
Ma, Christopher I.;
Sibley, L. David;
Sept, David;
Sasse, Florenz;
Maier, Martin E.

Publication type:

Article