Works by Shun Shimohama

Results: 91

Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy: The first report from Asian families.

Published in:

Epilepsia (Series 4), 2010, v. 51, n. 4, p. 690, doi. 10.1111/j.1528-1167.2009.02309.x

By:

Kawamata, Jun;
Ikeda, Akio;
Fujita, Youshi;
Usui, Keiko;
Shimohama, Shun;
Takahashi, Ryosuke

Publication type:

Article

Clinicopathologic Features of Oculopharyngodistal Myopathy With LRP12 CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes.

Published in:

JAMA Neurology, 2021, v. 78, n. 7, p. 853, doi. 10.1001/jamaneurol.2021.1509

By:

Kumutpongpanich, Theerawat;
Ogasawara, Masashi;
Ozaki, Ayami;
Ishiura, Hiroyuki;
Tsuji, Shoji;
Minami, Narihiro;
Hayashi, Shinichiro;
Noguchi, Satoru;
Iida, Aritoshi;
Nishino, Ichizo;
Mori-Yoshimura, Madoka;
Oya, Yasushi;
Ono, Kenjiro;
Shimizu, Toshio;
Kawata, Akihiro;
Shimohama, Shun;
Toyooka, Keiko;
Endo, Kaoru;
Toru, Shuta;
Sasaki, Oga

Publication type:

Article

Changes in protein kinase C isozymes in the rat hippocampal formation following hippocampal lesion.

Published in:

Hippocampus, 1993, v. 3, n. 1, p. 43, doi. 10.1002/hipo.450030105

By:

Shimohama, Shun;
Saitoh, Tsunao;
Gage, Fred H.

Publication type:

Article

Cocaine and Phenylephrine Eye Drop Test for Parkinson Disease.

Published in:

2005

By:

Sawada, Hideyuki;
Yamakawa, Kentarou;
Yamakado, Hodaka;
Hosokawa, Ryohei;
Ohba, Muneo;
Miyamoto, Kazuaki;
Kawamura, Takashi;
Shimohama, Shun

Publication type:

Letter

A case presenting electrophysiological and immunological characteristics of Fisher syndrome and Lambert‐Eaton myasthenic syndrome.

Published in:

Muscle & Nerve, 2021, v. 63, n. 3, p. E16, doi. 10.1002/mus.27136

By:

Ikeda, Kazuna;
Hirose, Bungo;
Yamamoto, Daisuke;
Hisahara, Shin;
Shimohama, Shun;
Shiraishi, Hirokazu;
Motomura, Masakatsu;
Imai, Tomihiro

Publication type:

Article

The spectrum of clinicopathological features in pure autonomic neuropathy.

Published in:

Journal of Neurology, 2012, v. 259, n. 10, p. 2067, doi. 10.1007/s00415-012-6458-x

By:

Koike, Haruki;
Hashimoto, Rina;
Tomita, Minoru;
Kawagashira, Yuichi;
Iijima, Masahiro;
Koyano, Shigeru;
Momoo, Takayuki;
Yuasa, Hiroyuki;
Mitake, Shigehisa;
Higashihara, Mana;
Kaida, Kenichi;
Yamamoto, Daisuke;
Hisahara, Shin;
Shimohama, Shun;
Nakae, Yoshiharu;
Johkura, Ken;
Vernino, Steven;
Sobue, Gen

Publication type:

Article

Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells.

Published in:

Glia (0894-1491), 1999, v. 25, n. 2, p. 154, doi. 10.1002/(SICI)1098-1136(19990115)25:2<154::AID-GLIA6>3.0.CO;2-S

By:

Kitamura, Yoshihisa;
Ota, Takashi;
Matsuoka, Yasuji;
Tooyama, Ikuo;
Kimura, Hiroshi;
Shimohama, Shun;
Nomura, Yasuyuki;
Gebicke-Haerter, Peter J.;
Taniguchi, Takashi

Publication type:

Article

Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans.

Published in:

Human Molecular Genetics, 2001, v. 10, n. 19, p. 2013, doi. 10.1093/hmg/10.19.2013

By:

Oeda, Tomoko;
Shimohama, Shun;
Kitagawa, Naoyuki;
Kohno, Ryuichi;
Imura, Tetsuya;
Shibasaki, Hiroshi;
Ishii, Naoaki

Publication type:

Article

3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats.

Published in:

Journal of Neuroscience Research, 2013, v. 91, n. 3, p. 462, doi. 10.1002/jnr.23160

By:

Suzuki, Syuuichirou;
Kawamata, Jun;
Matsushita, Takashi;
Matsumura, Akihiro;
Hisahara, Shin;
Takata, Kazuyuki;
Kitamura, Yoshihisa;
Kem, William;
Shimohama, Shun

Publication type:

Article

Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice.

Published in:

Journal of Neuroscience Research, 2013, v. 91, n. 1, p. 62, doi. 10.1002/jnr.23128

By:

Inden, Masatoshi;
Takata, Kazuyuki;
Nishimura, Kaneyasu;
Kitamura, Yoshihisa;
Ashihara, Eishi;
Yoshimoto, Kanji;
Ariga, Hiroyoshi;
Honmou, Osamu;
Shimohama, Shun

Publication type:

Article

Presenilin 1 is involved in the maturation of β‐site amyloid precursor protein‐cleaving enzyme 1 (BACE1).

Published in:

Journal of Neuroscience Research, 2007, v. 85, n. 1, p. 153, doi. 10.1002/jnr.21104

By:

Akira Kuzuya;
Kengo Uemura;
Naoyuki Kitagawa;
Nobuhisa Aoyagi;
Takeshi Kihara;
Haruaki Ninomiya;
Shoichi Ishiura;
Ryosuke Takahashi;
Shun Shimohama

Publication type:

Article

Iron accelerates the conversion of dopamine‐oxidized intermediates into melanin and provides protection in SH‐SY5Y cells.

Published in:

Journal of Neuroscience Research, 2005, v. 82, n. 1, p. 126, doi. 10.1002/jnr.20595

By:

Yasuhiko Izumi;
Hideyuki Sawada;
Noriyuki Yamamoto;
Toshiaki Kume;
Hiroshi Katsuki;
Shun Shimohama;
Akinori Akaike

Publication type:

Article

Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: Involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection.

Published in:

Annals of Neurology, 1998, v. 44, n. 5, p. 796, doi. 10.1002/ana.410440514

By:

Urushitani, Makoto;
Shimohama, Shun;
Kihara, Takeshi;
Sawada, Hideyuki;
Akaike, Akinori;
Ibi, Masakazu;
Inoue, Ryotaku;
Kitamura, Yoshihisa;
Taniguchi, Takashi;
Kimura, Jun

Publication type:

Article

Dopamine D2-type agonists protect mesencephalic neurons from glutamate neurotoxicity: Mechanisms of neuroprotective treatment against oxidative stress.

Published in:

Annals of Neurology, 1998, v. 44, n. 1, p. 110, doi. 10.1002/ana.410440117

By:

Sawada, Hideyuki;
Ibi, Masakazu;
Kihara, Takeshi;
Urushitani, Makoto;
Akaike, Akinori;
Kimura, Jun;
Shimohama, Shun

Publication type:

Article

Genetic variation in the ciliary neurotrophic factor receptor α gene and familial amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 1998, v. 43, n. 2, p. 275, doi. 10.1002/ana.410430225

By:

Imura, Tetsuya;
Shimohama, Shun;
Kawamata, Jun;
Kimura, Jun

Publication type:

Article

Reduction of low-molecular- weight acid phosphatase activity in Alzheimer brains.

Published in:

Annals of Neurology, 1993, v. 33, n. 6, p. 616, doi. 10.1002/ana.410330610

By:

Shimohama, Shun;
Fujimoto, Sadaki;
Taniguchi, Takashi;
Kameyama, Masakuni;
Kimura, Jun

Publication type:

Article

Changes in benzodiazepine receptors in alzheimer-type dementia.

Published in:

Annals of Neurology, 1988, v. 23, n. 4, p. 404, doi. 10.1002/ana.410230419

By:

Shimohama, Shun;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Kameyama, Masakuni

Publication type:

Article

A Heterozygous Missense Mutation in Adolescent-Onset Very Long-Chain Acyl-CoA Dehydrogenase Deficiency with Exercise-Induced Rhabdomyolysis.

Published in:

Tohoku Journal of Experimental Medicine, 2015, v. 235, n. 4, p. 305, doi. 10.1620/tjem.235.305

By:

Shin Hisahara;
Takashi Matsushita;
Hiroyasu Furuyama;
Go Tajima;
Yosuke Shigematsu;
Tomihiro Imai;
Shun Shimohama

Publication type:

Article

ROLE OF REDOX-ACTIVE IRON IN ALZHEIMER'S DISEASE.

Published in:

Current Medical Literature: Neurology, 2004, v. 20, n. 2, p. 25

By:

Honda, Kazuhiro;
Shimohama, Shun;
Smith, Mark A.;
Perry, George

Publication type:

Article

Successful intervention for overwhelming postsplenectomy infection caused by non-vaccine pneumococcal serotype 23A.

Published in:

Oxford Medical Case Reports, 2020, v. 20, n. 3, p. 1, doi. 10.1093/omcr/omaa018

By:

Kojima, Yuichi;
Ikeda, Kazuna;
Matsumura, Akihiro;
Shimohama, Shun;
Chang, Bin;
Yoshida, Takayuki;
Hamada, Kunio;
Ito, Akihide;
Ito, Toshiki

Publication type:

Article

Latitude and HLA-DRB1 alleles independently affect the emergence of cerebrospinal fluid IgG abnormality in multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2015, v. 21, n. 9, p. 1112, doi. 10.1177/1352458514560924

By:

Niino, Masaaki;
Sato, Shinya;
Fukazawa, Toshiyuki;
Yoshimura, Satoshi;
Hisahara, Shin;
Matsushita, Takuya;
Isobe, Noriko;
Yoshida, Kazuto;
Houzen, Hideki;
Miyazaki, Yusei;
Shimohama, Shun;
Kikuchi, Seiji;
Kira, Jun-ichi

Publication type:

Article

Ubiquitin-dependent rapid degradation conceals a cell-protective function of cytoplasmic SIRT3 against oxidative stress.

Published in:

Journal of Biochemistry, 2022, v. 171, n. 2, p. 201, doi. 10.1093/jb/mvab119

By:

Hayashi, Takashi;
Matsushita, Takashi;
Hisahara, Shin;
Iwahara, Naotoshi;
Kuno, Atsushi;
Kunimoto, Risa;
Hosoda, Ryusuke;
Tanno, Masaya;
Shimohama, Shun;
Horio, Yoshiyuki

Publication type:

Article

Microglial transplantation increases amyloid-β clearance in Alzheimer model rats

Published in:

FEBS Letters, 2007, v. 581, n. 3, p. 475, doi. 10.1016/j.febslet.2007.01.009

By:

Takata, Kazuyuki;
Kitamura, Yoshihisa;
Yanagisawa, Daijiro;
Morikawa, Shigehiro;
Morita, Masahito;
Inubushi, Toshiro;
Tsuchiya, Daiju;
Chishiro, Saori;
Saeki, Mana;
Taniguchi, Takashi;
Shimohama, Shun;
Tooyama, Ikuo

Publication type:

Article

Analysis of resources assisting in coping with swallowing difficulties for patients with Parkinson's disease: a cross-sectional study.

Published in:

2016

By:

Matsushima, Aiko;
Matsushima, Junichi;
Matsumoto, Akihisa;
Moriwaka, Fumio;
Honma, Sanae;
Itoh, Kazunori;
Yamada, Keiko;
Shimohama, Shun;
Ohnishi, Hirofumi;
Mori, Mitsuru

Publication type:

journal article

Novel G16S (GGC-AGC) mutation in the SOD-1 gene in a patient with apparently sporadic young-onset amyotrophic lateral sclerosis.

Published in:

Human Mutation, 1997, v. 9, n. 4, p. 356, doi. 10.1002/(SICI)1098-1004(1997)9:4<356::AID-HUMU9>3.0.CO;2-3

By:

Kawamata, Jun;
Shimohama, Shun;
Takano, Shin;
Harada, Kiyoshi;
Ueda, Kunihiro;
Kimura, Jun

Publication type:

Article

Variations in the BDNF Gene in Autopsy-Confirmed Alzheimer’s Disease and Dementia with Lewy Bodies in Japan.

Published in:

Dementia & Geriatric Cognitive Disorders, 2006, v. 22, n. 3, p. 216, doi. 10.1159/000094933

By:

Akatsu, Hiroyasu;
Yamagata, Hidehisa D.;
Kawamata, Jun;
Kamino, Kouzin;
Takeda, Masatoshi;
Yamamoto, Takayuki;
Miki, Tetsuro;
Tooyama, Ikuo;
Shimohama, Shun;
Kosaka, Kenji

Publication type:

Article

Inferior Temporal Lobe Atrophy and APOE Genotypes in Alzheimer's Disease.

Published in:

Dementia & Geriatric Cognitive Disorders, 1998, v. 9, n. 2, p. 90, doi. 10.1159/000017029

By:

Tanaka, Seigo;
Kawamata, Jun;
Shimohama, Shun;
Akaki, Hiroshi;
Akiguchi, Ichiro;
Kimura, Jun;
Ueda, Kunihiro

Publication type:

Article

Toxin-Induced and Genetic Animal Models of Parkinson's Disease.

Published in:

Parkinson's Disease (20420080), 2011, p. 1, doi. 10.4061/2011/951709

By:

Hisahara, Shin;
Shimohama, Shun

Publication type:

Article

SIRT1 deficiency interferes with membrane resealing after cell membrane injury.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218329

By:

Fujiwara, Daisuke;
Iwahara, Naotoshi;
Sebori, Rio;
Hosoda, Ryusuke;
Shimohama, Shun;
Kuno, Atsushi;
Horio, Yoshiyuki

Publication type:

Article

High mobility group box protein‐1 inhibits microglial Aβ clearance and enhances Aβ neurotoxicity.

Published in:

Journal of Neuroscience Research, 2004, v. 78, n. 6, p. 880, doi. 10.1002/jnr.20340

By:

Kazuyuki Takata;
Yoshihisa Kitamura;
Daiju Tsuchiya;
Toshiyuki Kawasaki;
Takashi Taniguchi;
Shun Shimohama

Publication type:

Article

Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.

Published in:

Journal of Neuroscience Research, 2003, v. 74, n. 2, p. 184, doi. 10.1002/jnr.10753

By:

Kengo Uemura;
Naoyuki Kitagawa;
Ryuichi Kohno;
Akira Kuzuya;
Takashi Kageyama;
Kazuhisa Chonabayashi;
Hiroshi Shibasaki;
Shun Shimohama

Publication type:

Article

Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling.

Published in:

Journal of Neuroscience Research, 2003, v. 73, n. 2, p. 166, doi. 10.1002/jnr.10641

By:

Kengo Uemura;
Naoyuki Kitagawa;
Ryuichi Kohno;
Akira Kuzuya;
Takashi Kageyama;
Hiroshi Shibasaki;
Shun Shimohama

Publication type:

Article

Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death.

Published in:

Journal of Neuroscience Research, 1998, v. 54, n. 5, p. 707, doi. 10.1002/(SICI)1097-4547(19981201)54:5<707::AID-JNR16>3.0.CO;2-T

By:

Sawada, Hideyuki;
Ibi, Masakazu;
Kihara, Takeshi;
Urushitani, Makoto;
Akaike, Akinori;
Shimohama, Shun

Publication type:

Article

Expression of protein kinase C isozymes in primary neuronal cultures of the rat cerebellum.

Published in:

Journal of Neuroscience Research, 1991, v. 29, n. 2, p. 261, doi. 10.1002/jnr.490290217

By:

Shimohama, Shun;
Uehara-Kunugi, Y.;
Terai, K.;
Taniguchi, T.;
Kimura, J.;
Saitoh, T.

Publication type:

Article

Depletion of Intracellular Glutathione Increases Susceptibility to Nitric Oxide in Mesencephalic Dopaminergic Neurons.

Published in:

Journal of Neurochemistry, 1999, v. 73, n. 4, p. 1696, doi. 10.1046/j.1471-4159.1999.731696.x

By:

Ibu, Masakazu;
Sawada, Hideyuki;
Kume, Toshiaki;
Katsuki, Hiroshi;
Kaneko, Shuji;
Shimohama, Shun;
Akaike, Akinori

Publication type:

Article

Ca2+-Dependent and Ca2+-Independent Protein Kinase C Changes in the Brains of Patients with Alzheimer's Disease.

Published in:

Journal of Neurochemistry, 1996, v. 67, n. 1, p. 317, doi. 10.1046/j.1471-4159.1996.67010317.x

By:

Matsushima, Hideyuki;
Shimohama, Shun;
Chachin, Motohiko;
Taniguchi, Takashi;
Kimura, Jun

Publication type:

Article

Alteration of Phospholipase C-δ Protein Level and Specific Activity in Alzheimer's Disease.

Published in:

Journal of Neurochemistry, 1995, v. 64, n. 6, p. 2629, doi. 10.1046/j.1471-4159.1995.64062629.x

By:

Shimohama, Shun;
Fujimoto, Sadaki;
Matsushima, Hideyuki;
Takenawa, Tadafumi;
Taniguchi, Takashi;
Perry, George;
Whitehouse, Peter J.;
Kimura, Jun

Publication type:

Article

Different Modulation of Protein Kinase C Isozymes in Dibutyryl Cyclic AMP-Differentiated PC12h Cells.

Published in:

Journal of Neurochemistry, 1994, v. 63, n. 1, p. 125, doi. 10.1046/j.1471-4159.1994.63010125.x

By:

Uehara-Kunugi, Yukiko;
Shimohama, Shun;
Kobayakawa, Hitoshi;
Tamura, Hitomi;
Taniguchi, Takashi

Publication type:

Article

[3H] N-[1-(2-Thienyl)cyclohexyl]-3,4-Piperidine ([3H]TCP) Binding in Human Frontal Cortex: Decreases in Alzheimer-Type Dementia.

Published in:

Journal of Neurochemistry, 1990, v. 54, n. 2, p. 526, doi. 10.1111/j.1471-4159.1990.tb01903.x

By:

Ninomiya, Haruaki;
Fukunaga, Reiko;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Shimohama, Shun;
Kameyama, Masakuni

Publication type:

Article

Changes in β-Adrenergic Receptor Subtypes in Alzheimer-Type Dementia.

Published in:

Journal of Neurochemistry, 1987, v. 48, n. 4, p. 1215, doi. 10.1111/j.1471-4159.1987.tb05649.x

By:

Shimohama, Shun;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Kameyama, Masakuni

Publication type:

Article

Biochemical Characterization of α-Adrenergic Receptors in Human Brain and Changes in Alzheimer-Type Dementia.

Published in:

Journal of Neurochemistry, 1986, v. 47, n. 4, p. 1294, doi. 10.1111/j.1471-4159.1986.tb00753.x

By:

Shimohama, Shun;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Kameyama, Masakuni

Publication type:

Article

Changes in Nicotinic and Muscarinic Cholinergic Receptors in Alzheimer-Type Dementia.

Published in:

Journal of Neurochemistry, 1986, v. 46, n. 1, p. 288, doi. 10.1111/j.1471-4159.1986.tb12960.x

By:

Shimohama, Shun;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Kameyama, Masakuni

Publication type:

Article

Biochemical Characterization of the Nicotinic Cholinergic Receptors in Human Brain: Binding of (-)-[3H]Nicotine.

Published in:

Journal of Neurochemistry, 1985, v. 45, n. 2, p. 604, doi. 10.1111/j.1471-4159.1985.tb04029.x

By:

Shimohama, Shun;
Taniguchi, Takashi;
Fujiwara, Motohatsu;
Kameyama, Masakuni

Publication type:

Article

Apoptosis in Alzheimer's disease—an update.

Published in:

Apoptosis, 2000, v. 5, n. 1, p. 9, doi. 10.1023/A:1009625323388

By:

Shimohama, Shun

Publication type:

Article

Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells.

Published in:

Neuropsychopharmacology Reports, 2023, v. 43, n. 3, p. 440, doi. 10.1002/npr2.12361

By:

Kato, Takeshi;
Nishimura, Kaneyasu;
Hirao, Masahiro;
Shimohama, Shun;
Takata, Kazuyuki

Publication type:

Article

Stimulating Nicotinic Receptors Trigger Multiple Pathways Attenuating Cytotoxicity in Models of Alzheimer's and Parkinson's Diseases.

Published in:

Journal of Alzheimer's Disease, 2011, v. 24, n. S2, p. 95

By:

Britton, Gabriel B.;
Smith, Mark A.;
Perry, George;
Sambamurti, Kumar;
Jagannatha Rao, K.S.;
Kawamata, Jun;
Shimohama, Shun

Publication type:

Article

Stimulating Nicotinic Receptors Trigger Multiple Pathways Attenuating Cytotoxicity in Models of Alzheimer's and Parkinson's Diseases.

Published in:

Journal of Alzheimer's Disease, 2011, v. 23, n. S1, p. 95, doi. 10.3233/JAD-2011-110173

By:

Kawamata, Jun;
Shimohama, Shun

Publication type:

Article

Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases.

Published in:

2011

By:

Kawamata, Jun;
Shimohama, Shun

Publication type:

Journal Article

Proteome analysis of brain proteins in Alzheimer's disease: subproteomics following sequentially extracted protein preparation.

Published in:

2004

By:

Shiozaki, Aiko;
Tsuji, Teruyuki;
Kohno, Ryuichi;
Kawamata, Jun;
Uemura, Kengo;
Teraoka, Hiroshi;
Shimohama, Shun

Publication type:

journal article

Association of novel and established polymorphisms in neuronal nicotinic acetylcholine receptors with sporadic Alzheimer's disease.

Published in:

Journal of Alzheimer's Disease, 2002, v. 4, n. 2, p. 71, doi. 10.3233/JAD-2002-4201

By:

Kawamata, Jun;
Shimohama, Shun

Publication type:

Article