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PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.
Published in:
2020
By:
- Shrestha, Stal;
- Kim, Min-Jeong;
- Eldridge, Mark;
- Lehmann, Michael L.;
- Frankland, Michael;
- Liow, Jeih-San;
- Yu, Zu-Xi;
- Cortes-Salva, Michelle;
- Telu, Sanjay;
- Henter, Ioline D.;
- Gallagher, Evan;
- Lee, Jae-Hoon;
- Fredericks, J. Megan;
- Poffenberger, Chelsie;
- Tye, George;
- Ruiz-Perdomo, Yanira;
- Anaya, Fernanda Juarez;
- Montero Santamaria, Jose A.;
- Gladding, Robert L.;
- Zoghbi, Sami S.
Publication type:
journal article
[ 11 C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 10, p. 2571, doi. 10.1177/0271678X211007949
By:
- Yan, Xuefeng;
- Telu, Sanjay;
- Dick, Rachel M;
- Liow, Jeih-San;
- Zanotti-Fregonara, Paolo;
- Morse, Cheryl L;
- Manly, Lester S;
- Gladding, Robert L;
- Shrestha, Stal;
- Lerchner, Walter;
- Nagai, Yuji;
- Minamimoto, Takafumi;
- Zoghbi, Sami S;
- Innis, Robert B;
- Pike, Victor W;
- Richmond, Barry J;
- Eldridge, Mark AG
Publication type:
Article
Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs.
Published in:
Journal of Nuclear Medicine, 2023, v. 64, n. 1, p. 159, doi. 10.2967/jnumed.122.264061
By:
- Min-Jeong Kim;
- Anaya, Fernanda Juarez;
- Manly, Lester S.;
- Jae-Hoon Lee;
- Jinsoo Hong;
- Shrestha, Stal;
- Telu, Sanjay;
- Henry, Katharine;
- Santamaria, Jose A. Montero;
- Liow, Jeih-San;
- Zanotti-Fregonara, Paolo;
- Shetty, H. Umesha;
- Zoghbi, Sami S.;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
Whole-body PET imaging in humans shows that 11C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 10, p. 1, doi. 10.2967/jnumed.122.264061
By:
- Kim, Min-Jeong;
- Anaya, Fernanda Juarez;
- Manly, Lester S.;
- Lee, Jae-Hoon;
- Hong, Jinsoo;
- Shrestha, Stal;
- Telu, Sanjay;
- Henry, Katharine;
- Montero Santamaria, Jose A.;
- Liow, Jeih-San;
- Zanotti-Fregonara, Paolo;
- Umesha Shetty, H.;
- Zoghbi, Sami S.;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
Whole-body PET imaging in humans shows that 11C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 9, p. 1, doi. 10.2967/jnumed.122.264061
By:
- Min-Jeong Kim;
- Juarez Anaya, Fernanda;
- Manly, Lester S.;
- Jae-Hoon Lee;
- Jinsoo Hong;
- Shrestha, Stal;
- Telu, Sanjay;
- Henry, Katharine;
- Montero Santamaria, Jose A.;
- Liow, Jeih-San;
- Zanotti-Fregonara, Paolo;
- Shetty, H. Umesha;
- Zoghbi, Sami S.;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
Whole-body PET imaging in humans shows that 11C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 7, p. 1, doi. 10.2967/jnumed.122.264061
By:
- Min-Jeong Kim;
- Anaya, Fernanda Juarez;
- Manly, Lester S.;
- Jae-Hoon Lee;
- Jinsoo Hong;
- Shrestha, Stal;
- Telu, Sanjay;
- Henry, Katharine;
- Montero Santamaria, Jose A.;
- Jeih-San Liow;
- Zanotti-Fregonara, Paolo;
- Shetty, H. Umesha;
- Zoghbi, Sami S.;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys.
Published in:
Journal of Nuclear Medicine, 2018, v. 59, n. 12, p. 1907, doi. 10.2967/jnumed.118.211144
By:
- Min-Jeong Kim;
- Shrestha, Stal S.;
- Cortes, Michelle;
- Singh, Prachi;
- Morse, Cheryl;
- Liow, Jeih-San;
- Gladding, Robert L.;
- Brouwer, Chad;
- Henry, Katharine;
- Gallagher, Evan;
- Tye, George L.;
- Zoghbi, Sami S.;
- Fujita, Masahiro;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.
Published in:
Journal of Nuclear Medicine, 2017, v. 58, n. 2, p. 320, doi. 10.2967/jnumed.116.178996
By:
- Ikawa, Masamichi;
- Lohith, Talakad G.;
- Shrestha, Stal;
- Telu, Sanjay;
- Zoghbi, Sami S.;
- Castellano, Sabrina;
- Taliani, Sabrina;
- Da Settimo, Federico;
- Fujita, Masahiro;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
The 5-HT1A Receptor PET Radioligand 11C-CUMI-101 Has Significant Binding to α1-Adrenoceptors in Human Cerebellum, Limiting Its Use as a Reference Region.
Published in:
Journal of Nuclear Medicine, 2016, v. 57, n. 12, p. 1945, doi. 10.2967/jnumed.116.174151
By:
- Shrestha, Stal S.;
- Liow, Jeih-San;
- Jenko, Kimberly;
- Ikawa, Masamichi;
- Zoghbi, Sami S.;
- Innis, Robert B.
Publication type:
Article
11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain.
Published in:
Journal of Nuclear Medicine, 2014, v. 55, n. 1, p. 141, doi. 10.2967/jnumed.113.125831
By:
- Shrestha, Stal Saurav;
- Liow, Jeih-San;
- Shuiyu Lu;
- Jenko, Kimberly;
- Gladding, Robert L.;
- Svenningsson, Per;
- Morse, Cheryl L.;
- Zoghbi, Sami S.;
- Pike, Victor W.;
- Innis, Robert B.
Publication type:
Article
2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET—Synthesis, Triage, and Radiolabeling.
Published in:
Molecules, 2018, v. 23, n. 11, p. 2850, doi. 10.3390/molecules23112850
By:
- Cortes-Salva, Michelle Y.;
- Shrestha, Stal;
- Singh, Prachi;
- Morse, Cheryl L.;
- Jenko, Kimberly J.;
- Montero Santamaria, Jose A.;
- Zoghbi, Sami S.;
- Innis, Robert B.;
- Pike, Victor W.;
- Roivainen, Anne
Publication type:
Article

Found: 11

PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.

[ 11 C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.

Whole-Body PET Imaging in Humans Shows That <sup>11</sup>C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs.

Whole-body PET imaging in humans shows that <sup>11</sup>C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.

Whole-body PET imaging in humans shows that 11C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.

Whole-body PET imaging in humans shows that <sup>11</sup>C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.

Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys.

<sup>11</sup>C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.

The 5-HT<sub>1A</sub> Receptor PET Radioligand <sup>11</sup>C-CUMI-101 Has Significant Binding to α<sub>1</sub>-Adrenoceptors in Human Cerebellum, Limiting Its Use as a Reference Region.

<sup>11</sup>C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α<sub>1</sub> Adrenoceptors in Brain.

2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET—Synthesis, Triage, and Radiolabeling.