Works by Shinotoh, Hitoshi

Results: 74

A new method to quantify tau pathologies with C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter.

Published in:

EJNMMI Research, 2016, v. 6, n. 1, p. 1, doi. 10.1186/s13550-016-0182-y

By:

Kimura, Yasuyuki;
Endo, Hironobu;
Ichise, Masanori;
Shimada, Hitoshi;
Seki, Chie;
Ikoma, Yoko;
Shinotoh, Hitoshi;
Yamada, Makiko;
Higuchi, Makoto;
Zhang, Ming-Rong;
Suhara, Tetsuya

Publication type:

Article

Noninvasive k3 estimation method for slow dissociation PET ligands: application to [11C]Pittsburgh compound B.

Published in:

EJNMMI Research, 2013, v. 3, n. 1, p. 1, doi. 10.1186/2191-219X-3-76

By:

Sato, Koichi;
Fukushi, Kiyoshi;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Hirano, Shigeki;
Tanaka, Noriko;
Suhara, Tetsuya;
Irie, Toshiaki;
Ito, Hiroshi

Publication type:

Article

Neuroimaging of PD, PSP, CBD and MSA -- PET and SPECT studies.

Published in:

Journal of Neurology, 2006, v. 253, p. 30, doi. 10.1007/s00415-006-3006-6

By:

Shinotoh, Hitoshi

Publication type:

Article

PBB3 imaging in Parkinsonian disorders: Evidence for binding to tau and other proteins.

Published in:

2017

By:

Perez‐Soriano, Alexandra;
Arena, Julieta E.;
Dinelle, Katie;
Miao, Qing;
McKenzie, Jessamyn;
Neilson, Nicole;
Puschmann, Andreas;
Schaffer, Paul;
Shinotoh, Hitoshi;
Smith‐Forrester, Jenna;
Shahinfard, Elham;
Vafai, Nasim;
Wile, Daryl;
Wszolek, Zbigniew;
Higuchi, Makoto;
Sossi, Vesna;
Stoessl, A. Jon

Publication type:

journal article

β-Amyloid in Lewy body disease is related to Alzheimer's disease-like atrophy.

Published in:

2013

By:

Shimada, Hitoshi;
Shinotoh, Hitoshi;
Hirano, Shigeki;
Miyoshi, Michie;
Sato, Koichi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Fukushi, Kiyoshi;
Irie, Toshiaki;
Ito, Hiroshi;
Higuchi, Makoto;
Kuwabara, Satoshi;
Suhara, Tetsuya

Publication type:

journal article

β-amyloid in lewy body disease is related to Alzheimer's disease-like atrophy.

Published in:

Movement Disorders, 2013, v. 28, n. 2, p. 169, doi. 10.1002/mds.25286

By:

Shimada, Hitoshi;
Shinotoh, Hitoshi;
Hirano, Shigeki;
Miyoshi, Michie;
Sato, Koichi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Fukushi, Kiyoshi;
Irie, Toshiaki;
Ito, Hiroshi;
Higuchi, Makoto;
Kuwabara, Satoshi;
Suhara, Tetsuya

Publication type:

Article

PET study of brain acetylcholinesterase in cerebellar degenerative disorders.

Published in:

Movement Disorders, 2008, v. 23, n. 8, p. 1154, doi. 10.1002/mds.22056

By:

Hirano, Shigeki;
Shinotoh, Hitoshi;
Arai, Kimihito;
Aotsuka, Akiyo;
Yasuno, Fumihiko;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Sato, Koichi;
Fukushi, Kiyoshi;
Tanada, Shuji;
Hattori, Takamichi;
Irie, Toshiaki

Publication type:

Article

Misfolded protein deposits in Parkinson's disease and Parkinson's disease-related cognitive impairment, a [11C]PBB3 study.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00708-z

By:

Matarazzo, Michele;
Pérez-Soriano, Alexandra;
Vafai, Nasim;
Shahinfard, Elham;
Cheng, Kevin Ju-Chieh;
McKenzie, Jessamyn;
Neilson, Nicole;
Miao, Qing;
Schaffer, Paul;
Shinotoh, Hitoshi;
Kordower, Jeffrey H.;
Sossi, Vesna;
Stoessl, A. Jon

Publication type:

Article

Relationship between striatal [123I]β-CIT binding and four major clinical signs in Parkinson’s disease.

Published in:

Annals of Nuclear Medicine, 2000, v. 14, n. 3, p. 199, doi. 10.1007/BF02987860

By:

Shinotoh, Hitoshi;
Uchida, Yoshitaka;
Ito, Hisao;
Hattori, Takamichi

Publication type:

Article

In vivo PET classification of tau pathologies in patients with frontotemporal dementia.

Published in:

Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae075

By:

Kubota, Manabu;
Endo, Hironobu;
Takahata, Keisuke;
Tagai, Kenji;
Suzuki, Hisaomi;
Onaya, Mitsumoto;
Sano, Yasunori;
Yamamoto, Yasuharu;
Kurose, Shin;
Matsuoka, Kiwamu;
Seki, Chie;
Shinotoh, Hitoshi;
Kawamura, Kazunori;
Zhang, Ming-Rong;
Takado, Yuhei;
Shimada, Hitoshi;
Higuchi, Makoto

Publication type:

Article

Differentiation Between Dementia With Lewy Bodies And Alzheimer's Disease Using Voxel-Based Morphometry Of Structural MRI: A Multicenter Study.

Published in:

Neuropsychiatric Disease & Treatment, 2019, v. 15, p. 2715, doi. 10.2147/NDT.S222966

By:

Matsuda, Hiroshi;
Yokoyama, Kota;
Sato, Noriko;
Ito, Kengo;
Nemoto, Kiyotaka;
Oba, Hiroshi;
Hanyu, Haruo;
Kanetaka, Hidekazu;
Mizumura, Sunao;
Kitamura, Shin;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Suhara, Tetsuya;
Terada, Hitoshi;
Nakatsuka, Tomoya;
Kawakatsu, Shinobu;
Hayashi, Hiroshi;
Asada, Takashi;
Ono, Tetsutaro;
Goto, Tomoaki

Publication type:

Article

Cholinergic imaging in corticobasal syndrome, progressive supranuclear palsy and frontotemporal dementia.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 7, p. 2058, doi. 10.1093/brain/awq120

By:

Hirano, Shigeki;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Aotsuka, Akiyo;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Sato, Koichi;
Ito, Hiroshi;
Kuwabara, Satoshi;
Fukushi, Kiyoshi;
Irie, Toshiaki;
Suhara, Tetsuya

Publication type:

Article

In Vivo Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy.

Published in:

Annals of Neurology, 2024, v. 96, n. 2, p. 247, doi. 10.1002/ana.26962

By:

Hirata, Kosei;
Matsuoka, Kiwamu;
Tagai, Kenji;
Endo, Hironobu;
Tatebe, Harutsugu;
Ono, Maiko;
Kokubo, Naomi;
Kataoka, Yuko;
Oyama, Asaka;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Obata, Takayuki;
Dehghani, Masoumeh;
Near, Jamie;
Kawamura, Kazunori;
Zhang, Ming‐Rong;
Shimada, Hitoshi;
Shimizu, Hiroshi;
Kakita, Akiyoshi;
Yokota, Takanori

Publication type:

Article

Altered Brain Energy Metabolism Related to Astrocytes in Alzheimer's Disease.

Published in:

Annals of Neurology, 2024, v. 95, n. 1, p. 104, doi. 10.1002/ana.26797

By:

Hirata, Kosei;
Matsuoka, Kiwamu;
Tagai, Kenji;
Endo, Hironobu;
Tatebe, Harutsugu;
Ono, Maiko;
Kokubo, Naomi;
Oyama, Asaka;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Obata, Takayuki;
Dehghani, Masoumeh;
Near, Jamie;
Kawamura, Kazunori;
Zhang, Ming‐Rong;
Shimada, Hitoshi;
Yokota, Takanori;
Tokuda, Takahiko;
Higuchi, Makoto;
Takado, Yuhei

Publication type:

Article

The aftermath of boxing: Longitudinal changes of cerebral retention patterns of 18F‐florzolotau (18F‐APN‐1607) in the former professional boxers.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076455

By:

Takahata, Keisuke;
Kubota, Manabu;
Tagai, Kenji;
Endo, Hironobu;
Miyata, Mari;
Saito, Fumie;
Tatebe, Harutsugu;
Matsuoka, Kiwamu;
Kurose, Shin;
Ichihashi, Masanori;
Kataoka, Yuko;
Hirata, Kosei;
Matsumoto, Hideki;
Seki, Chie;
Kokubo, Naomi;
Shinotoh, Hitoshi;
Oya, Masaki;
Sano, Yasunori;
Yamamoto, Yasuharu;
Kawamura, Kazunori

Publication type:

Article

In vivo characterization of tau accumulation in patients with frontotemporal dementia: A PET study with 18F‐florzolotau.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078492

By:

Kubota, Manabu;
Endo, Hironobu;
Takahata, Keisuke;
Tagai, Kenji;
Suzuki, Hisaomi;
Onaya, Mitsumoto;
Sano, Yasunori;
Yamamoto, Yasuharu;
Kurose, Shin;
Matsuoka, Kiwamu;
Seki, Chie;
Shinotoh, Hitoshi;
Kawamura, Kazunori;
Zhang, Ming‐Rong;
Takado, Yuhei;
Shimada, Hitoshi;
Higuchi, Makoto

Publication type:

Article

Development and Comparison of a Novel Mid‐Region Directed p‐Tau 181 Assay with Tau Positron Emission Tomography in Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078621

By:

Tagai, Kenji;
Tatebe, Harutsugu;
Matsuura, Sayo;
Zhang, Hong;
Kokubo, Naomi;
Matsuoka, Kiwamu;
Endo, Hironobu;
Oyama, Asaka;
Hirata, Kosei;
Shinotoh, Hitoshi;
Kataoka, Yuko;
Matsumoto, Hideki;
Oya, Masaki;
Kurose, Shin;
Takahata, Keisuke;
Ichihashi, Masanori;
Kubota, Manabu;
Seki, Chie;
Shimada, Hitoshi;
Takado, Yuhei

Publication type:

Article

Altered brain energy metabolism related to astrocytes in tauopathies.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059834

By:

Hirata, Kosei;
Matsuoka, Kiwamu;
Tagai, Kenji;
Endo, Hironobu;
Kokubo, Naomi;
Tatebe, Harutsugu;
Zhang, Hong;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Ono, Maiko;
Obata, Takayuki;
Kawamura, Kazunori;
Zhang, Ming‐Rong;
Shimada, Hitoshi;
Tokuda, Takahiko;
Yokota, Takanori;
Takado, Yuhei;
Higuchi, Makoto

Publication type:

Article

A tau PET study of primary age‐related tauopathy in healthy volunteers: Neuroimaging / Normal brain aging.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041730

By:

Shinotoh, Hitoshi;
Shimada, Hitoshi;
Tagai, Kenji;
Kubota, Manabu;
Takahata, Keisuke;
Sano, Yasunori;
Yamamoto, Yasuharu;
Matsuoka, Kiwamu;
Takado, Yuhei;
Nakano, Yoshikazu;
Hirano, Shigeki;
Zhang, Ming‐Rong;
Suhara, Tetsuya;
Higuchi, Makoto

Publication type:

Article

P2‐382: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P749, doi. 10.1016/j.jalz.2019.06.2789

By:

Shimada, Hitoshi;
Tagai, Kenji;
Kubota, Manabu;
Takahata, Keisuke;
Takado, Yuhei;
Shinotoh, Hitoshi;
Yamamoto, Yasuharu;
Sano, Yasunori;
Seki, Chie;
Hirano, Shigeki;
Kimura, Yasuyuki;
Ichise, Masanori;
Ono, Maiko;
Tempest, Paul;
Jang, Ming-Kuei;
Sahara, Naruhiko;
Kawamura, Kazunori;
Zhang, Ming-Rong;
Kuwabara, Satoshi;
Hattori, Nobutaka

Publication type:

Article

IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294

By:

Shimada, Hitoshi;
Tagai, Kenji;
Kubota, Manabu;
Takahata, Keisuke;
Takado, Yuhei;
Shinotoh, Hitoshi;
Yamamoto, Yasuharu;
Sano, Yasunori;
Seki, Chie;
Hirano, Shigeki;
Kimura, Yasuyuki;
Ichise, Masanori;
Ono, Maiko;
Tempest, Paul;
Jang, Ming-Kuei;
Sahara, Naruhiko;
Kawamura, Kazunori;
Zhang, Ming-Rong;
Kuwabara, Satoshi;
Hattori, Nobutaka

Publication type:

Article

IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294

By:

Shimada, Hitoshi;
Tagai, Kenji;
Kubota, Manabu;
Takahata, Keisuke;
Takado, Yuhei;
Shinotoh, Hitoshi;
Yamamoto, Yasuharu;
Sano, Yasunori;
Seki, Chie;
Hirano, Shigeki;
Kimura, Yasuyuki;
Ichise, Masanori;
Ono, Maiko;
Tempest, Paul;
Jang, Ming-Kuei;
Sahara, Naruhiko;
Kawamura, Kazunori;
Zhang, Ming-Rong;
Kuwabara, Satoshi;
Hattori, Nobutaka

Publication type:

Article

P1‐125: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P318, doi. 10.1016/j.jalz.2018.06.128

By:

Shimada, Hitoshi;
Ono, Maiko;
Tagai, Kenji;
Kubota, Manabu;
Kitamura, Soichiro;
Takuwa, Hiroyuki;
Seki, Chie;
Kimura, Yasuyuki;
Ichise, Masanori;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Yamamoto, Naoyoshi;
Sano, Yasunori;
Takado, Yuhei;
Tempest, Paul;
Jang, Ming-Kuei;
Seibyl, John;
Barret, Olivier;
Alagille, David;
Marek, Kenneth

Publication type:

Article

IC‐P‐217: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P177, doi. 10.1016/j.jalz.2018.06.2284

By:

Shimada, Hitoshi;
Ono, Maiko;
Tagai, Kenji;
Kubota, Manabu;
Kitamura, Soichiro;
Takuwa, Hiroyuki;
Seki, Chie;
Kimura, Yasuyuki;
Ichise, Masanori;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Yamamoto, Naoyoshi;
Sano, Yasunori;
Takado, Yuhei;
Tempest, Paul;
Jang, Ming-Kuei;
Seibyl, John;
Barret, Olivier;
Alagille, David;
Marek, Kenneth

Publication type:

Article

IC‐P‐221: TAU ACCUMULATION PREDICTS PROGRESSION OF DEMENTIA IN SUBJECTS WITH EARLY ALZHEIMER'S DISEASE IN THE ALZHEIMER'S DISEASE SPECTRUM: A [11C]PBB3 POSITRON EMISSION TOMOGRAPHY STUDY.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P180, doi. 10.1016/j.jalz.2018.06.2288

By:

Tagai, Kenji;
Shimada, Hitoshi;
Kitamura, Soichiro;
Takahata, Keisuke;
Kubota, Manabu;
Takado, Yuhei;
Shinotoh, Hitoshi;
Nakano, Yoshikazu;
Ishii, Tatsuya;
Hirano, Shigeki;
Shigeta, Masahiro;
Suhara, Tetsuya;
Higuchi, Makoto

Publication type:

Article

Dynamic alterations in the central glutamatergic status following food and glucose intake: in vivo multimodal assessments in humans and animal models.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 11, p. 2928, doi. 10.1177/0271678X211004150

By:

Kubota, Manabu;
Kimura, Yasuyuki;
Shimojo, Masafumi;
Takado, Yuhei;
Duarte, Joao MN;
Takuwa, Hiroyuki;
Seki, Chie;
Shimada, Hitoshi;
Shinotoh, Hitoshi;
Takahata, Keisuke;
Kitamura, Soichiro;
Moriguchi, Sho;
Tagai, Kenji;
Obata, Takayuki;
Nakahara, Jin;
Tomita, Yutaka;
Tokunaga, Masaki;
Maeda, Jun;
Kawamura, Kazunori;
Zhang, Ming-Rong

Publication type:

Article

Correction to: First‑in‑human in vivo imaging and quantification of monoacylglycerol lipase in the brain: a PET study with 18F‑T‑401.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 9, p. 3299, doi. 10.1007/s00259-022-05795-9

By:

Takahata, Keisuke;
Seki, Chie;
Kimura, Yasuyuki;
Kubota, Manabu;
Ichise, Masanori;
Sano, Yasunori;
Yamamoto, Yasuharu;
Tagai, Kenji;
Shimada, Hitoshi;
Kitamura, Soichiro;
Matsuoka, Kiwamu;
Endo, Hironobu;
Shinotoh, Hitoshi;
Kawamura, Kazunori;
Zhang, Ming‑Rong;
Takado, Yuhei;
Higuchi, Makoto

Publication type:

Article

First-in-human in vivo imaging and quantification of monoacylglycerol lipase in the brain: a PET study with 18F-T-401.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 9, p. 3150, doi. 10.1007/s00259-021-05671-y

By:

Takahata, Keisuke;
Seki, Chie;
Kimura, Yasuyuki;
Kubota, Manabu;
Ichise, Masanori;
Sano, Yasunori;
Yamamoto, Yasuharu;
Tagai, Kenji;
Shimada, Hitoshi;
Kitamura, Soichiro;
Matsuoka, Kiwamu;
Endo, Hironobu;
Shinotoh, Hitoshi;
Kawamura, Kazunori;
Zhang, Ming-Rong;
Takado, Yuhei;
Higuchi, Makoto

Publication type:

Article

Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: a positron emission tomography study.

Published in:

2000

By:

Shinotoh, Hitoshi;
Namba, Hiroki;
Fukushi, Kiyoshi;
Nagatsuka, Shin-Ichiro;
Tanaka, Noriko;
Aotsuka, Akiyo;
Ota, Tsuneyoshi;
Tanada, Shuji;
Irie, Toshiaki;
Shinotoh, H;
Namba, H;
Fukushi, K;
Nagatsuka, S;
Tanaka, N;
Aotsuka, A;
Ota, T;
Tanada, S;
Irie, T

Publication type:

journal article

Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and progressive supranuclear palsy.

Published in:

1999

By:

Shinotoh, Hitoshi;
Namba, Hiroki;
Yamaguchi, Mika;
Fukushi, Kiyoshi;
Nagatsuka, Shin-Ichiro;
Iyo, Masaomi;
Asahina, Masto;
Hattori, Takamichi;
Tanada, Shuzi;
Irie, Toshiaki;
Shinotoh, H;
Namba, H;
Yamaguchi, M;
Fukushi, K;
Nagatsuka, S;
Iyo, M;
Asahina, M;
Hattori, T;
Tanada, S;
Irie, T

Publication type:

journal article

Parkinsonism induced by solvent abuse.

Published in:

1994

By:

Uitti, Ryan J.;
Snow, Barry J.;
Shinotoh, Hitoshi;
Vingerhoets, Francois J. G.;
Hayward, Margo;
Hashimoto, Stanley;
Richmond, John;
Markey, Sanford P.;
Markey, Carol J.;
Calne, Donald B.;
Uitti, R J;
Snow, B J;
Shinotoh, H;
Vingerhoets, F J;
Hayward, M;
Hashimoto, S;
Richmond, J;
Markey, S P;
Markey, C J;
Calne, D B

Publication type:

journal article

FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P146, doi. 10.1016/j.jalz.2017.06.2573

By:

Shimada, Hitoshi;
Kitamura, Soichiro;
Ono, Maiko;
Kimura, Yasuyuki;
Ichise, Masanori;
Takahata, Keisuke;
Moriguchi, Sho;
Kubota, Manabu;
Ishii, Tatsuya;
Takado, Yuhei;
Seki, Chie;
Hirano, Shigeki;
Shinotoh, Hitoshi;
Sahara, Naruhiko;
Tempest, Paul;
Tamagnan, Gilles;
Seibyl, John;
Barret, Olivier;
Alagille, David;
Zhang, Ming-Rong

Publication type:

Article

INTRODUCING THE ASSOCIATION BETWEEN CHILDREN AND DEMENTED ELDERLY (ABCDE) PROJECT.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1165, doi. 10.1016/j.jalz.2017.06.1714

By:

Hirano, Shigeki;
Shimizu, Keisuke;
Murayama, Noriko;
Ishikawa, Moeno;
Furukawa, Shogo;
Kojima, Kazuho;
Ishikawa, Ai;
Nakano, Yoshikazu;
Sakurai, Toru;
Sasaki, Tsuyoshi;
Iyo, Masaomi;
Kuwabara, Satoshi;
Shimada, Hitoshi;
Shinotoh, Hitoshi

Publication type:

Article

FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1104, doi. 10.1016/j.jalz.2017.06.1594

By:

Shimada, Hitoshi;
Kitamura, Soichiro;
ONO, Maiko;
Kimura, Yasuyuki;
Ichise, Masanori;
Takahata, Keisuke;
Moriguchi, Sho;
Kubota, Manabu;
Ishii, Tatsuya;
Takado, Yuhei;
Seki, Chie;
Hirano, Shigeki;
Shinotoh, Hitoshi;
Sahara, Naruhiko;
Tempest, Paul;
Tamagnan, Gilles;
Seibyl, John;
Barret, Olivier;
Alagille, David;
Zhang, Ming-Rong

Publication type:

Article

[11C]PBB3 PET VISUALIZES TAU AGGREGATES IN PATIENTS WITH FTDP-17 MAPT GENE MUTATION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P135, doi. 10.1016/j.jalz.2016.06.217

By:

Shinotoh, Hitoshi;
Sahara, Naruhiko;
Shimada, Hitoshi;
Ikeuchi, Takeshi;
Shunske, Koga;
Strogonsky, Audrey J.;
Nishioka, Kenya;
Hanyu, Haruo;
van Swieten, John C.;
Ono, Maiko;
Kimura, Yasuyuki;
Hirano, Shigeki;
Ishii, Kenji;
Zhang, Ming-Rong;
Trojanowski, John Q.;
M-Y Lee, Virginia;
Dickson, Dennis W.;
Wszolek, Zbigniew;
Hattori, Nobutaka;
Higuchi, Makoto

Publication type:

Article

THE ASSOCIATION BETWEEN Aβ AND TAU ACCUMULATIONS AND ITS INFLUENCE ON CLINICAL FEATURES IN AGING AND ALZHEIMER’S DISEASE SPECTRUM BRAINS: [11C]PBB3 PET STUDY.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P503, doi. 10.1016/j.jalz.2016.06.998

By:

Shimada, Hitoshi;
Suhara, Tetsuya;
Shinotoh, Hitoshi;
Endo, Hironobu;
Niwa, Fumitoshi;
Kitamura, Soichiro;
Hirano, Shigeki;
Kimura, Yasuyuki;
Yamada, Makiko;
Sahara, Naruhiko;
Zhang, Ming-Rong;
Kuwabara, Satoshi;
Higuchi, Makoto

Publication type:

Article

THE ASSOCIATION BETWEEN AB AND TAU ACCUMULATIONS AND ITS INFLUENCE ON CLINICAL FEATURES IN AGING AND ALZHEIMER’S DISEASE SPECTRUM BRAINS: [11C]PBB3 PET STUDY.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1, doi. 10.1016/j.jalz.2016.06.062

By:

Shimada, Hitoshi;
Suhara, Tetsuya;
Shinotoh, Hitoshi;
Endo, Hironobu;
Niwa, Fumitoshi;
Kitamura, Soichiro;
Hirano, Shigeki;
Kimura, Yasuyuki;
Yamada, Makiko;
Sahara, Naruhiko;
Zhang, Ming-Rong;
Kuwabara, Satoshi;
Higuchi, Makoto

Publication type:

Article

Age correlates with cortical acetylcholinesterase decline in Alzheimer's disease patients: A PET study

Published in:

2012

By:

Hirano, Shigeki;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Sato, Koichi;
Kuwabara, Satoshi;
Toshiaki, Irie;
Suhara, Tetsuya

Publication type:

Abstract

In vivo detection of amyloid deposition using [11C]AZD2184 PET

Published in:

2012

By:

Shimada, Hitoshi;
Shinotoh, Hitoshi;
Hirano, Shigeki;
Mori, Takaaki;
Eguchi, Yoko;
Tanaka, Noriko;
Kodaka, Fumitoshi;
Fujiwara, Hironobu;
Kimura, Yasuyuki;
Kuwabara, Satoshi;
Takano, Harumasa;
Higuchi, Makoto;
Ito, Hiroshi;
Suhara, Tetsuya

Publication type:

Abstract

Age correlates with cortical acetylcholinesterase decline in Alzheimer's disease patients: A PET study

Published in:

2012

By:

Hirano, Shigeki;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Sato, Koichi;
Kuwabara, Satoshi;
Toshiaki, Irie;
Suhara, Tetsuya

Publication type:

Abstract

In vivo detection of amyloid deposition using [11C]AZD2184 PET

Published in:

2012

By:

Shimada, Hitoshi;
Shinotoh, Hitoshi;
Hirano, Shigeki;
Mori, Takaaki;
Eguchi, Yoko;
Tanaka, Noriko;
Kodaka, Fumitoshi;
Fujiwara, Hironobu;
Kimura, Yasuyuki;
Kuwabara, Satoshi;
Takano, Harumasa;
Higuchi, Makoto;
Ito, Hiroshi;
Suhara, Tetsuya

Publication type:

Abstract

Longitudinal [11C]PIB PET study in healthy elderly persons, patients with mild cognitive impairment, and Alzheimer's disease

Published in:

2011

By:

Shinotoh, Hitoshi;
Shimada, Hitoshi;
Hirano, Shigeki;
Tanaka, Noriko;
Sato, Koichi;
Kiyoshi, Fukushi;
Toshiaki, Irie;
Eguchi, Yoko;
Ito, Hiroshi;
Suhara, Tetsuya

Publication type:

Abstract

Correlation between cerebral blood flow and amyloid deposition in Alzheimer's disease studied by [11C]PIB PET

Published in:

2010

By:

Shinotoh, Hitoshi;
Shimada, Hioshi;
Miyoshi, Miche;
Hirano, Shigeki;
Tanaka, Noriko;
Sato, Koichi;
Fukushi, Kiyoshi;
Irie, Toshiaki;
Ito, Hiroshi;
Suhara, Tetsuya

Publication type:

Abstract

Lewy body disease with dementia can be well-differentiated from Alzheimer's disease by measurement of cerebral cortical acetylcholinesterase activity by PET

Published in:

2010

By:

Shimada, Hitoshi;
Shinotoh, Hitoshi;
Hirano, Shigeki;
Miyoshi, Michie;
Sato, Koichi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Asahina, Masato;
Aotsuka, Akiyo;
Fukushi, Kiyoshi;
Ito, Hiroshi;
Kuwabara, Satoshi;
Irie, Toshiaki;
Suhara, Tetsuya

Publication type:

Abstract

P2-080: Mapping of amyloid deposition in early- and late-onset Alzheimer's disease

Published in:

2008

By:

Shinotoh, Hitoshi

Publication type:

Abstract

P1-266: Changes in beta-amyloid deposition by pet study

Published in:

2008

By:

Miyoshi, Michie;
Shinotoh, Hitoshi;
Shimada, Hitoshi;
Sato, Kouichi;
Fukushi, Kiyoshi;
Ito, Hiroshi;
Suhara, Tetsuya;
Matsumoto, Masayasu;
Irie, Toshiaki

Publication type:

Abstract

IC-01-05: Mapping of amyloid deposition in early- and late-onset Alzheimer's disease

Published in:

2008

By:

Shinotoh, Hitoshi

Publication type:

Abstract

P-059: Voxel-based analysis of [11C]PIB uptake in Alzheimer’s disease and mild cognitive impairment

Published in:

2007

By:

Shinotoh, Hitoshi;
Kiyoshi, Fukushi;
Hirano, Shigeki;
Shimada, Hitoshi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Sato, Koichi;
Suhara, Tetsuya;
Irie, Toshiaki

Publication type:

Abstract

IC-P-014: Mapping of amyloid load in Alzheimer’s disease and mild cognitive impairment

Published in:

2006

By:

Tanaka, Noriko;
Shinotoh, Hitoshi;
Fukushi, Kiyoshi;
Ota, Tsuneyoshi;
Hirano, Shigeki;
Sato, Koichi;
Shimada, Hitoshi;
Tanada, Shuji;
Irie, Toshiaki

Publication type:

Abstract

IC-104-03: Mapping of progressive loss of acetylcholinesterase activities in early- and late-onset Alzheimer’s disease

Published in:

2006

By:

Shinotoh, Hitoshi;
Fukushi, Kiyoshi;
Tanaka, Noriko;
Ota, Tsuneyoshi;
Hirano, Shigeki;
Sato, Koichi;
Shimada, Hitoshi;
Tanada, Shuji;
Irie, Toshiaki

Publication type:

Abstract