Works matching AU Shin, Young G.

Results: 38

Rapid and simultaneous quantification of a mixture of biopharmaceuticals by a liquid chromatography/quadrupole time-of-flight mass spectrometric method in rat plasma following cassette-dosing.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2018, v. 32, n. 11, p. 889, doi. 10.1002/rcm.8123

By:

Park, Min‐Ho;
Byeon, Jin‐Ju;
Shin, Seok‐Ho;
Kim, Nahye;
Park, Yuri;
Lee, Byeong;
Choi, Jangmi;
Shin, Young G.

Publication type:

Article

Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay.

Published in:

Pharmaceutics, 2021, v. 13, n. 1, p. 125, doi. 10.3390/pharmaceutics13010125

By:

Lee, Byeong ill;
Park, Seo-jin;
Park, Yuri;
Shin, Seok-Ho;
Choi, Jang-mi;
Park, Min-jae;
Lim, Jeong-hyeon;
Kim, Sun Young;
Lee, Hyangsook;
Shin, Young G.;
Iacobelli, Stefano;
Ippoliti, Rodolfo

Publication type:

Article

Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats.

Published in:

Pharmaceutics, 2019, v. 11, n. 7, p. 354, doi. 10.3390/pharmaceutics11070354

By:

Na, Young-Guk;
Byeon, Jin-Ju;
Huh, Hyun Wook;
Kim, Min-Ki;
Shin, Young G.;
Lee, Hong-Ki;
Cho, Cheong-Weon

Publication type:

Article

A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse.

Published in:

Pharmaceutics, 2018, v. 10, n. 2, p. 69, doi. 10.3390/pharmaceutics10020069

By:

Shin, Seok-Ho;
Park, Min-Ho;
Byeon, Jin-Ju;
Lee, Byeong Ill;
Park, Yuri;
Ko, Ah-Ra;
Seong, Mi-Ran;
Lee, Soyeon;
Kim, Mi Ra;
Seo, Jinwook;
Jung, Myung Eun;
Jin, Dong-Kyu;
Shin, Young G.

Publication type:

Article

Qualification and Application of a Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method for the Determination of Adalimumab in Rat Plasma.

Published in:

Pharmaceutics, 2018, v. 10, n. 2, p. 61, doi. 10.3390/pharmaceutics10020061

By:

Park, Yuri;
Kim, Nahye;
Choi, Jangmi;
Park, Min-Ho;
Lee, Byeong Ill;
Shin, Seok-Ho;
Byeon, Jin-Ju;
Shin, Young G.

Publication type:

Article

Investigation of pharmacokinetic properties of a PEGylated bilirubin nanoparticle in male Sprague-Dawley rats using liquid chromatography-quadrupole time-of-flight mass spectrometry.

Published in:

Xenobiotica, 2024, v. 54, n. 8, p. 563, doi. 10.1080/00498254.2023.2284859

By:

Park, Seo-jin;
Lim, Jeong-hyeon;
Lee, Jiyu;
Lee, Jeongmin;
Hwang, Sangsoo;
Kim, Hyunjin;
Jo, Seunghyun;
Shin, Duckhyang;
MA, Sang Ho;
Kim, Myung L.;
Shin, Young G.

Publication type:

Article

Human microdosing and mice xenograft data of AGM-130 applied to estimate efficacious doses in patients.

Published in:

2017

By:

Park, Wan-Su;
Park, Gab-jin;
Han, Seunghoon;
Ban, Sooho;
Park, Moon-Young;
Kim, San-ho;
Kim, Seon-Myung;
Kim, Yong-Chul;
Kim, Hyung;
Shin, Young;
Yim, Dong-Seok;
Kim, Hyung Sik;
Shin, Young G

Publication type:

journal article

Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin.

Published in:

2017

By:

Min-Ho Park;
Seok-Ho Shin;
Jin-Ju Byeon;
Gwan-Ho Lee;
Byung-Yong Yu;
Shin, Young G.

Publication type:

Case Study

Profiling and Identification of Omeprazole Metabolites in Mouse Brain and Plasma by Isotope Ratio-Monitoring Liquid Chromatography-Mass Spectrometric Method.

Published in:

Life (2075-1729), 2020, v. 10, n. 7, p. 115, doi. 10.3390/life10070115

By:

Shin, Seok-Ho;
Park, Yuri;
Park, Min-Ho;
Byeon, Jin-Ju;
Lee, Byeong ill;
Choi, Jangmi;
Shin, Young G.

Publication type:

Article

Drug--drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer.

Published in:

Drug Design, Development & Therapy, 2017, v. 11, p. 1043, doi. 10.2147/DDDT.S131797

By:

Gab-jin Park;
Soo Hyeon Bae;
Wan-Su Park;
Seunghoon Han;
Min-Ho Park;
Seok-Ho Shin;
Young G. Shin;
Dong-Seok Yim

Publication type:

Article

Quantification for Antibody-Conjugated Drug in Trastuzumab Emtansine and Application to In Vitro Linker Stability and In Vivo Pharmacokinetic Study in Rat Using an Immuno-Affinity Capture Liquid Chromatography-Mass Spectrometric Method.

Published in:

Applied Sciences (2076-3417), 2021, v. 11, n. 20, p. 9437, doi. 10.3390/app11209437

By:

Park, Seo-jin;
Lee, Byeong ill;
Park, Min-Ho;
Choi, Jangmi;
Park, Yuri;
Park, Min-jae;
Lim, Jeong-hyeon;
Lee, Jiyu;
Hwang, Sangsoo;
Lee, Jeongmin;
Shin, Young G.

Publication type:

Article

Qualification and application of liquid chromatography-quadrupole time-offlight mass spectrometric method for the determination of carisbamate in rat plasma and prediction of its human pharmacokinetics using physiologically based pharmacokinetic modeling.

Published in:

Translational & Clinical Pharmacology, 2020, v. 28, n. 3, p. 147, doi. 10.12793/tcp.2020.28.e15

By:

Byeong ill Lee;
Jeong-hyeon Lim;
Min-Ho Park;
Seok-Ho Shin;
Jin-Ju Byeon;
Jang-mi Choi;
Seo-jin Park;
Min-jae Park;
Yuri Park;
Shin, Young G.

Publication type:

Article

Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425.

Published in:

Translational & Clinical Pharmacology, 2015, v. 23, n. 2, p. 59, doi. 10.12793/tcp.2015.23.2.59

By:

Shin, Young G.;
Meijering, Henri;
van Heuveln, Fred H.;
Wieling, Jaap;
Halladay, Jason;
Sahasranaman, Srikumar;
Hop, Cornelis E.C.A.

Publication type:

Article

First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2022, v. 40, n. 5, p. 1001, doi. 10.1007/s10637-022-01277-9

By:

Janku, Filip;
Beom, Seung-Hoon;
Moon, Yong Wha;
Kim, Tae Won;
Shin, Young G.;
Yim, Dong-Seok;
Kim, Gun Min;
Kim, Hyo Song;
Kim, Sun Young;
Cheong, Jae-Ho;
Lee, Young Woo;
Geiger, Barb;
Yoo, Sanghee;
Thurston, Archie;
Welsch, Dean;
Rudoltz, Marc S.;
Rha, Sun Young

Publication type:

Article

Fast and Simple Qualitative/Semi‐Quantitative Analysis of Monoclonal Antibody Mixtures Using Liquid Chromatography–Electrospray Triple Time‐of‐Flight Mass Spectrometry.

Published in:

Bulletin of the Korean Chemical Society, 2018, v. 39, n. 12, p. 1380, doi. 10.1002/bkcs.11610

By:

Byeon, Jin‐Ju;
Park, Min‐Ho;
Shin, Seok‐Ho;
Shin, Young G.

Publication type:

Article

Study of Ultra‐Sensitive AMS Method to Identify Drug–Drug Interactions between Ciprofloxacin and Microdose <sup>14</sup>C‐Caffeine.

Published in:

Bulletin of the Korean Chemical Society, 2018, v. 39, n. 6, p. 773, doi. 10.1002/bkcs.11468

By:

Lee, Gwan‐Ho;
Oh, Min‐Seok;
Park, Min‐Ho;
Shin, Young G.;
Song, Jong Han;
Yu, Byung‐Yong

Publication type:

Article

Short Insulin Tolerance Test May Determine Thiazolidinediones Treatment in Type 2 Diabetes.

Published in:

Diabetes, 2007, v. 56, p. A578

By:

Lee, Mi Y.;
Koh, Jang H.;
Jung, Pil M.;
Shim, Myoung S.;
Kim, Mi J.;
Shin, Jang Y.;
Shin, Young G.;
Chung, Choon H.

Publication type:

Article

Prevalence of Metabolic Syndrome According to the Progression of Menopause in Korean Women: Relationship Between the Menstrual Stage and Metabolic Syndrome Components.

Published in:

Diabetes, 2007, v. 56, p. A255

By:

Koh, Jang H.;
Lee, Mi Y.;
Nam, Soo M.;
Jung, Pil M.;
Lee, Il Y.;
Kim, Mi J.;
Shin, Jang Y.;
Shin, Young G.;
Chung, Choon H.

Publication type:

Article

Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 74, n. 5, p. 788, doi. 10.1111/j.1365-2125.2012.04281.x

By:

Graham, Richard A.;
Hop, Cornelis E. C. A.;
Borin, Marie T.;
Lum, Bert L.;
Colburn, Dawn;
Chang, Ilsung;
Shin, Young G.;
Malhi, Vikram;
Low, Jennifer A.;
Dresser, Mark J.

Publication type:

Article

Quantification of Methylene Blue and Evaluation of Its Pharmacokinetics in ICR Mice by Liquid Chromatography‐Quadrupole Time‐of‐Flight Mass Spectrometry Using Difluoroacetic Acid.

Published in:

Biomedical Chromatography, 2025, v. 39, n. 6, p. 1, doi. 10.1002/bmc.70080

By:

Park, Seo‐jin;
Lee, Juwon;
Hwang, Sangsoo;
Lim, Jeong‐hyeon;
Cho, Hyunjin;
Shin, Young G.

Publication type:

Article

Liquid chromatography‐high resolution mass spectrometric method for the quantification of monomethyl auristatin E (MMAE) and its preclinical pharmacokinetics.

Published in:

Biomedical Chromatography, 2020, v. 34, n. 8, p. 1, doi. 10.1002/bmc.4855

By:

Lee, Byeong ill;
Park, Min‐Ho;
Choi, Jangmi;
Shin, Seok‐Ho;
Byeon, Jin‐Ju;
Park, Yuri;
Shin, Young G.

Publication type:

Article

A single liquid chromatography–quadrupole time‐of‐flight mass spectrometric method for the quantification of total antibody, antibody‐conjugated drug and free payload of antibody–drug conjugates.

Published in:

Biomedical Chromatography, 2018, v. 32, n. 7, p. 1, doi. 10.1002/bmc.4229

By:

Byeon, Jin‐Ju;
Park, Min‐Ho;
Shin, Seok‐Ho;
Lee, Byeong ill;
Park, Yuri;
Choi, Jangmi;
Kim, Nahye;
Kang, Yeonjae;
Shin, Young G.

Publication type:

Article

Quantification and application of a liquid chromatography–tandem mass spectrometric method for the determination of WKYMVm peptide in rat using solid‐phase extraction.

Published in:

Biomedical Chromatography, 2018, v. 32, n. 3, p. 1, doi. 10.1002/bmc.4107

By:

Lee, Byeong ill;
Park, Min‐Ho;
Heo, Soon Chul;
Park, Yuri;
Shin, Seok‐Ho;
Byeon, Jin‐Ju;
Kim, Jae Ho;
Shin, Young G.

Publication type:

Article

Qualification and application of a liquid chromatography-quadrupole time-of-flight mass spectrometric method for the determination of trastuzumab in rat plasma.

Published in:

Biomedical Chromatography, 2016, v. 30, n. 4, p. 625, doi. 10.1002/bmc.3606

By:

Park, Min‐Ho;
Lee, Min‐Woo;
Shin, Young G.

Publication type:

Article

Validation of a liquid chromatography-triple quadrupole mass spectrometric method for the determination of 5-nitro-5′-hydroxy-indirubin-3′-oxime (AGM-130) in human plasma and its application to microdose clinical trial.

Published in:

Biomedical Chromatography, 2016, v. 30, n. 3, p. 323, doi. 10.1002/bmc.3551

By:

Park, Min‐Ho;
Lee, Yun Young;
Cho, Kyung Hee;
La, Sookie;
Lee, Hee Joo;
Yim, Dong‐Seok;
Ban, Sooho;
Park, Moon‐Young;
Kim, Yong‐Chul;
Kim, Yoon‐Gyoon;
Shin, Young G.

Publication type:

Article

Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of GDC-0152 in human plasma using solid-phase extraction.

Published in:

Biomedical Chromatography, 2013, v. 27, n. 1, p. 102, doi. 10.1002/bmc.2754

By:

Shin, Young G.;
Jones, Steve A.;
Murakami, Stan C.;
Budha, Nageshwar;
Ware, Joseph;
Wong, Harvey;
Buonarati, Michael H.;
Dean, Brian;
Hop, Cornelis E. C. A.

Publication type:

Article

Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of GDC-0834 and its metabolite in human plasma using semi-automated 96-well protein precipitation.

Published in:

Biomedical Chromatography, 2012, v. 26, n. 11, p. 1444, doi. 10.1002/bmc.2716

By:

Shin, Young G.;
Jones, Steve A.;
Murakami, Stan C.;
Liu, Lichuan;
Wong, Harvey;
Buonarati, Michael H.;
Hop, Cornelis E. C. A.

Publication type:

Article

Evaluation of In Vivo Prepared Albumin-Drug Conjugate Using Immunoprecipitation Linked LC-MS Assay and Its Application to Mouse Pharmacokinetic Study.

Published in:

Molecules, 2023, v. 28, n. 7, p. 3223, doi. 10.3390/molecules28073223

By:

Lim, Jeong-Hyeon;
Park, Minjae;
Park, Yuri;
Park, Seo-Jin;
Lee, Jiyu;
Hwang, Sangsoo;
Lee, Jeongmin;
Lee, Yujin;
Jo, Eunjeong;
Shin, Young G.

Publication type:

Article

Investigation of In Vitro and In Vivo Metabolism of α-Amanitin in Rats Using Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method.

Published in:

Molecules, 2022, v. 27, n. 23, p. 8612, doi. 10.3390/molecules27238612

By:

Lee, Jiyu;
Lee, Byeong ill;
Choi, Jangmi;
Park, Yuri;
Park, Seo-Jin;
Park, Minjae;
Lim, Jeong-Hyeon;
Hwang, Sangsoo;
Lee, Jeong-Min;
Shin, Young G.

Publication type:

Article

Quantitative Analysis of Daporinad (FK866) and Its In Vitro and In Vivo Metabolite Identification Using Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry.

Published in:

Molecules, 2022, v. 27, n. 6, p. 2011, doi. 10.3390/molecules27062011

By:

Park, Minjae;
Lee, Byeong Ill;
Choi, Jangmi;
Park, Yuri;
Park, Seo-Jin;
Lim, Jeong-Hyeon;
Lee, Jiyu;
Shin, Young G.

Publication type:

Article

Quantification and Metabolite Identification of Sulfasalazine in Mouse Brain and Plasma Using Quadrupole-Time-of-Flight Mass Spectrometry.

Published in:

Molecules, 2021, v. 26, n. 4, p. 1179, doi. 10.3390/molecules26041179

By:

Choi, Jangmi;
Park, Min-Ho;
Shin, Seok-Ho;
Byeon, Jin-Ju;
Lee, Byeong ill;
Park, Yuri;
Shin, Young G.;
Główka, Franciszek;
Karaźniewicz-Łada, Marta

Publication type:

Article

Pharmacokinetics and Metabolism of Liposome-Encapsulated 2,4,6-Trihydroxygeranylacetophenone in Rats Using High-Resolution Orbitrap Liquid Chromatography Mass Spectrometry.

Published in:

Molecules, 2020, v. 25, n. 13, p. 3069, doi. 10.3390/molecules25133069

By:

Alkhateeb, Yamen;
Jarrar, Qais Bashir;
Abas, Faridah;
Rukayadi, Yaya;
Tham, Chau Ling;
Hay, Yuen Kah;
Shaari, Khozirah;
Shin, Young G.

Publication type:

Article

Assessment of Pharmacokinetics and Metabolism Profiles of SCH 58261 in Rats Using Liquid Chromatography–Mass Spectrometric Method.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2209, doi. 10.3390/molecules25092209

By:

Park, Yuri;
Park, Min-Ho;
Byeon, Jin-Ju;
Shin, Seok-Ho;
Lee, Byeong ill;
Choi, Jang-mi;
Kim, Nahye;
Park, Seo-jin;
Park, Min-jae;
Lim, Jeong-hyeon;
Shin, Young G.

Publication type:

Article

Quantification of an Antibody-Conjugated Drug in Fat Plasma by an Affinity Capture LC-MS/MS Method for a Novel Prenyl Transferase-Mediated Site-Specific Antibody–Drug Conjugate.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1515, doi. 10.3390/molecules25071515

By:

Lee, Byeong ill;
Park, Min-Ho;
Byeon, Jin-Ju;
Shin, Seok-Ho;
Choi, Jangmi;
Park, Yuri;
Park, Yun-Hee;
Chae, Jeiwook;
Shin, Young G.

Publication type:

Article

In Vitro, In Silico, and In Vivo Assessments of Pharmacokinetic Properties of ZM241385.

Published in:

Molecules, 2020, v. 25, n. 5, p. 1106, doi. 10.3390/molecules25051106

By:

Byeon, Jin-Ju;
Park, Min-Ho;
Shin, Seok-Ho;
Park, Yuri;
Lee, Byeong ill;
Choi, Jang-mi;
Kim, Nahye;
Park, Seo-jin;
Park, Min-jae;
Lim, Jeong-hyeon;
Na, Young-Guk;
Shin, Young G.;
Lei, Zhentian;
Barker, James

Publication type:

Article

Comparative Pharmacokinetics of Gallic Acid, Protocatechuic Acid, and Quercitrin in Normal and Pyelonephritis Rats after Oral Administration of a Polygonum capitatum Extract.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3873, doi. 10.3390/molecules24213873

By:

Huang, Yong;
Zhou, Zuying;
Yang, Wu;
Gong, Zipeng;
Li, Yueting;
Chen, Siying;
Wang, Yonglin;
Wang, Aimin;
Lan, Yanyu;
Liu, Ting;
Zheng, Lin;
Shin, Young G.;
Xiao, Jianbo

Publication type:

Article

Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry.

Published in:

Molecules, 2019, v. 24, n. 15, p. 2754, doi. 10.3390/molecules24152754

By:

Park, Min-Ho;
Lee, Byeong ill;
Byeon, Jin-Ju;
Shin, Seok-Ho;
Choi, Jangmi;
Park, Yuri;
Shin, Young G.;
Lei, Yu;
Dong, Qiuchen;
Liu, Yixin

Publication type:

Article

Quantitative Analysis of Tozadenant Using Liquid Chromatography-Mass Spectrometric Method in Rat Plasma and Its Human Pharmacokinetics Prediction Using Physiologically Based Pharmacokinetic Modeling.

Published in:

Molecules, 2019, v. 24, n. 7, p. 1295, doi. 10.3390/molecules24071295

By:

Lee, Byeong ill;
Park, Min-Ho;
Shin, Seok-Ho;
Byeon, Jin-Ju;
Park, Yuri;
Kim, Nahye;
Choi, Jangmi;
Shin, Young G.;
Tsunoda, Makoto

Publication type:

Article