Works by Shimizu, Ippei

Results: 25

Maintenance of Subcutaneous Fat Homeostasis Improves Systemic Metabolic Dysfunction in Obesity.

Published in:

2015

By:

Ippei Shimizu;
Yohko Yoshida;
Tohru Minamino;
Shimizu, Ippei;
Yoshida, Yohko;
Minamino, Tohru

Publication type:

journal article

A role for circadian clock in metabolic disease.

Published in:

Hypertension Research, 2016, v. 39, n. 7, p. 483, doi. 10.1038/hr.2016.12

By:

Shimizu, Ippei;
Yoshida, Yohko;
Minamino, Tohru

Publication type:

Article

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.

Published in:

2007

By:

Sano, Masanori;
Minamino, Tohru;
Toko, Haruhiro;
Miyauchi, Hideyuki;
Orimo, Masayuki;
Qin, Yingjie;
Akazawa, Hiroshi;
Tateno, Kaoru;
Kayama, Yosuke;
Harada, Mutsuo;
Shimizu, Ippei;
Asahara, Takayuki;
Hamada, Hirofumi;
Tomita, Shuhei;
Molkentin, Jeffrey D.;
Zou, Yunzeng;
Komuro, Issei

Publication type:

Letter

Preliminary study on the effects of boysenberry juice intake on brown adipose tissue activity in healthy adults.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76452-4

By:

Furuuchi, Ryo;
Kato, Satoshi;
Maejima, Daisuke;
Amano, Tatsuro;
Fujiki, Shinya;
Shimizu, Ippei;
Minamino, Tohru

Publication type:

Article

Investigation of anti-cardiac hypertrophy effects of Andrographis paniculata ethanolic extract by modulating proinflammation and oxidative stress via Nrf2/NF-ĸB/NLRP3 signaling pathway: In silico and in vitro approaches.

Published in:

Journal of Applied Pharmaceutical Science, 2025, v. 15, n. 6, p. 277, doi. 10.7324/JAPS.2025.226923

By:

Fadhillah, Muhamad Rizqy;
Wibowo, Heri;
Bustami, Arleni;
Sukmawati, Dewi;
Tedjo, Aryo;
Khatimah, Nurul Gusti;
Shimizu, Ippei;
Arozal, Wawaimuli

Publication type:

Article

Vascular rarefaction mediates whitening of brown fat in obesity.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 5, p. 2099, doi. 10.1172/JCI71643

By:

Shimizu, Ippei;
Aprahamian, Tamar;
Kikuchi, Ryosuke;
Shimizu, Ayako;
Papanicolaou, Kyriakos N.;
MacLauchlan, Susan;
Maruyama, Sonomi;
Walsh, Kenneth

Publication type:

Article

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.

Published in:

2010

By:

Shimizu, Ippei;
Minamino, Tohru;
Toko, Haruhiro;
Okada, Sho;
Ikeda, Hiroyuki;
Yasuda, Noritaka;
Tateno, Kaoru;
Moriya, Junji;
Yokoyama, Masataka;
Nojima, Aika;
Gou Young Koh;
Akazawa, Hiroshi;
Shiojima, Ichiro;
Kahn, C. Ronald;
Abel, E. Dale;
Komuro, Issei;
Koh, Gou Young

Publication type:

journal article

Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-19245-x

By:

Yoshida, Yohko;
Shimizu, Ippei;
Shimada, Atsuhiro;
Nakahara, Keita;
Yanagisawa, Sachiko;
Kubo, Minoru;
Fukuda, Shinji;
Ishii, Chiharu;
Yamamoto, Hiromitsu;
Ishikawa, Takamasa;
Kano, Kuniyuki;
Aoki, Junken;
Katsuumi, Goro;
Suda, Masayoshi;
Ozaki, Kazuyuki;
Yoshida, Yutaka;
Okuda, Shujiro;
Ohta, Shigeo;
Okamoto, Shiki;
Minokoshi, Yasuhiko

Publication type:

Article

Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182422

By:

Suda, Masayoshi;
Shimizu, Ippei;
Yoshida, Yohko;
Hayashi, Yuka;
Ikegami, Ryutaro;
Katsuumi, Goro;
Wakasugi, Takayuki;
Yoshida, Yutaka;
Okuda, Shujiro;
Soga, Tomoyoshi;
Minamino, Tohru

Publication type:

Article

PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis.

Published in:

EMBO Journal, 2024, v. 43, n. 21, p. 4846, doi. 10.1038/s44318-024-00196-0

By:

Hsiao, Yung Ting;
Yoshida, Yohko;
Okuda, Shujiro;
Abe, Manabu;
Mizuno, Seiya;
Takahashi, Satoru;
Nakagami, Hironori;
Morishita, Ryuichi;
Kamimura, Kenya;
Terai, Shuji;
Aung, Tin May;
Li, Ji;
Furihata, Takaaki;
Tang, Jing Yuan;
Walsh, Kenneth;
Ishigami, Akihito;
Minamino, Tohru;
Shimizu, Ippei

Publication type:

Article

Role of circulating molecules in age-related cardiovascular and metabolic disorders.

Published in:

Inflammation & Regeneration, 2022, v. 42, n. 1, p. 1, doi. 10.1186/s41232-021-00187-2

By:

Hsiao, Yung Ting;
Shimizu, Ippei;
Yoshida, Yohko;
Minamino, Tohru

Publication type:

Article

Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 8, p. 949, doi. 10.15252/emmm.201506151

By:

Maruyama, Sonomi;
Nakamura, Kazuto;
Papanicolaou, Kyriakos N;
Sano, Soichi;
Shimizu, Ippei;
Asaumi, Yasuhide;
Hoff, Maurice J;
Ouchi, Noriyuki;
Recchia, Fabio A;
Walsh, Kenneth

Publication type:

Article

Role of smooth muscle cell p53 in pulmonary arterial hypertension.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0212889

By:

Wakasugi, Takayuki;
Shimizu, Ippei;
Yoshida, Yohko;
Hayashi, Yuka;
Ikegami, Ryutaro;
Suda, Masayoshi;
Katsuumi, Goro;
Nakao, Masaaki;
Hoyano, Makoto;
Kashimura, Takeshi;
Nakamura, Kazufumi;
Ito, Hiroshi;
Nojiri, Takashi;
Soga, Tomoyoshi;
Minamino, Tohru

Publication type:

Article

Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202051

By:

Furuuchi, Ryo;
Shimizu, Ippei;
Yoshida, Yohko;
Hayashi, Yuka;
Ikegami, Ryutaro;
Suda, Masayoshi;
Katsuumi, Goro;
Wakasugi, Takayuki;
Nakao, Masaaki;
Minamino, Tohru

Publication type:

Article

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1464, doi. 10.1038/nm.3703

By:

Kikuchi, Ryosuke;
Nakamura, Kazuto;
MacLauchlan, Susan;
Ngo, Doan Thi-Minh;
Shimizu, Ippei;
Fuster, Jose Javier;
Katanasaka, Yasufumi;
Yoshida, Sumiko;
Qiu, Yan;
Yamaguchi, Terry P;
Matsushita, Tadashi;
Murohara, Toyoaki;
Gokce, Noyan;
Bates, David O;
Hamburg, Naomi M;
Walsh, Kenneth

Publication type:

Article

A crucial role for adipose tissue p53 in the regulation of insulin resistance.

Published in:

Nature Medicine, 2009, v. 15, n. 9, p. 1082, doi. 10.1038/nm.2014

By:

Minamino, Tohru;
Orimo, Masayuki;
Shimizu, Ippei;
Kunieda, Takeshige;
Yokoyama, Masataka;
Ito, Takashi;
Nojima, Aika;
Nabetani, Akira;
Oike, Yuichi;
Matsubara, Hisahiro;
Ishikawa, Fuyuki;
Komuro, Issei

Publication type:

Article

Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.

Published in:

2015

By:

Suzuki, Hirofumi;
Kayama, Yosuke;
Sakamoto, Masaya;
Iuchi, Hiroyuki;
Shimizu, Ippei;
Yoshino, Takuya;
Katoh, Daisuke;
Nagoshi, Tomohisa;
Tojo, Katsuyoshi;
Minamino, Tohru;
Yoshimura, Michihiro;
Utsunomiya, Kazunori

Publication type:

Journal Article

Arachidonate 12/15- Lipoxygenase-Induced Inflammation and Oxidative Stress Are Involved in the Development of Diabetic Cardiomyopathy.

Published in:

Diabetes, 2015, v. 64, n. 2, p. 618, doi. 10.2337/db13-1896

By:

Hirofumi Suzuki;
Yosuke Kayama;
Masaya Sakamoto;
Hiroyuki Iuchi;
Ippei Shimizu;
Takuya Yoshino;
Daisuke Katoh;
Tomohisa Nagoshi;
Katsuyoshi Tojo;
Tohru Minamino;
Michihiro Yoshimura;
Kazunori Utsunomiya

Publication type:

Article

Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86209-y

By:

Hsiao, Yung Ting;
Shimizu, Ippei;
Wakasugi, Takayuki;
Yoshida, Yohko;
Ikegami, Ryutaro;
Hayashi, Yuka;
Suda, Masayoshi;
Katsuumi, Goro;
Nakao, Masaaki;
Ozawa, Takuya;
Izumi, Daisuke;
Kashimura, Takeshi;
Ozaki, Kazuyuki;
Soga, Tomoyoshi;
Minamino, Tohru

Publication type:

Article

Notch Signaling Regulates the Lifespan of Vascular Endothelial Cells via a p16-Dependent Pathway.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100359

By:

Yoshida, Yohko;
Hayashi, Yuka;
Suda, Masayoshi;
Tateno, Kaoru;
Okada, Sho;
Moriya, Junji;
Yokoyama, Masataka;
Nojima, Aika;
Yamashita, Masakatsu;
Kobayashi, Yoshio;
Shimizu, Ippei;
Minamino, Tohru

Publication type:

Article

Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069178

By:

Nojima, Aika;
Yamashita, Masakatsu;
Yoshida, Yohko;
Shimizu, Ippei;
Ichimiya, Harumi;
Kamimura, Naomi;
Kobayashi, Yoshio;
Ohta, Shigeo;
Ishii, Naoaki;
Minamino, Tohru

Publication type:

Article

Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10522-3

By:

Suda, Masayoshi;
Shimizu, Ippei;
Katsuumi, Goro;
Hsiao, Chieh Lun;
Yoshida, Yohko;
Matsumoto, Naomi;
Yoshida, Yutaka;
Katayama, Akihiro;
Wada, Jun;
Seki, Masahide;
Suzuki, Yutaka;
Okuda, Shujiro;
Ozaki, Kazuyuki;
Nakanishi-Matsui, Mayumi;
Minamino, Tohru

Publication type:

Article

Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10522-3

By:

Suda, Masayoshi;
Shimizu, Ippei;
Katsuumi, Goro;
Hsiao, Chieh Lun;
Yoshida, Yohko;
Matsumoto, Naomi;
Yoshida, Yutaka;
Katayama, Akihiro;
Wada, Jun;
Seki, Masahide;
Suzuki, Yutaka;
Okuda, Shujiro;
Ozaki, Kazuyuki;
Nakanishi-Matsui, Mayumi;
Minamino, Tohru

Publication type:

Article

Empagliflozin maintains capillarization and improves cardiac function in a murine model of left ventricular pressure overload.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97787-2

By:

Nakao, Masaaki;
Shimizu, Ippei;
Katsuumi, Goro;
Yoshida, Yohko;
Suda, Masayoshi;
Hayashi, Yuka;
Ikegami, Ryutaro;
Hsiao, Yung Ting;
Okuda, Shujiro;
Soga, Tomoyoshi;
Minamino, Tohru

Publication type:

Article

Cereblon contributes to cardiac dysfunction by degrading Cav1.2α.

Published in:

European Heart Journal, 2022, v. 43, n. 20, p. 1973, doi. 10.1093/eurheartj/ehac072

By:

Park, Nammi;
Marquez, Jubert;
Pham, Trong Kha;
Ko, Tae Hee;
Youm, Jae Boum;
Kim, Min;
Choi, Seung Hak;
Moon, Jiyoung;
Flores, Jessa;
Ko, Kyung Soo;
Rhee, Byoung Doo;
Shimizu, Ippei;
Minamino, Tohru;
Ha, Jae Du;
Hwang, Jong Yeon;
Yang, Seung Joo;
Park, Chul-Seung;
Kim, Hyoung Kyu;
Han, Jin

Publication type:

Article