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Salmonella type III effector SpvC, a phosphothreonine lyase, contributes to reduction in inflammatory response during intestinal phase of infection.
Published in:
Cellular Microbiology, 2012, v. 14, n. 4, p. 485, doi. 10.1111/j.1462-5822.2011.01733.x
By:
- Haneda, Takeshi;
- Ishii, Yuta;
- Shimizu, Hiromichi;
- Ohshima, Keiko;
- Iida, Naoyuki;
- Danbara, Hirofumi;
- Okada, Nobuhiko
Publication type:
Article
Efficacy and safety of filgotinib for ulcerative colitis: A real‐world multicenter retrospective study in Japan.
Published in:
Alimentary Pharmacology & Therapeutics, 2024, v. 59, n. 11, p. 1413, doi. 10.1111/apt.17961
By:
- Akiyama, Shintaro;
- Yokoyama, Kaoru;
- Yagi, Soichi;
- Shinzaki, Shinichiro;
- Tsuruta, Kozo;
- Yoshioka, Shinichiro;
- Sako, Minako;
- Shimizu, Hiromichi;
- Kobayashi, Mariko;
- Sakurai, Toshiyuki;
- Nomura, Kei;
- Shibuya, Tomoyoshi;
- Takahara, Masahiro;
- Hiraoka, Sakiko;
- Sugai, Kyohei;
- Yanai, Shunichi;
- Yoshida, Atsushi;
- Koroku, Miki;
- Omori, Teppei;
- Saruta, Masayuki
Publication type:
Article
Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease.
Published in:
Alimentary Pharmacology & Therapeutics, 2021, v. 54, n. 8, p. 1052, doi. 10.1111/apt.16551
By:
- Takenaka, Kento;
- Kawamoto, Ami;
- Hibiya, Shuji;
- Suzuki, Kohei;
- Fujii, Toshimitsu;
- Motobayashi, Maiko;
- Shimizu, Hiromichi;
- Nagahori, Masakazu;
- Saito, Eiko;
- Okamoto, Ryuichi;
- Watanabe, Mamoru;
- Ohtsuka, Kazuo
Publication type:
Article
Pancolonic endoscopic and histologic evaluation for relapse prediction in patients with ulcerative colitis in clinical remission.
Published in:
Alimentary Pharmacology & Therapeutics, 2021, v. 53, n. 8, p. 900, doi. 10.1111/apt.16310
By:
- Kaneshiro, Miyuki;
- Takenaka, Kento;
- Suzuki, Kohei;
- Fujii, Toshimitsu;
- Hibiya, Shuji;
- Kawamoto, Ami;
- Motobayashi, Maiko;
- Shimizu, Hiromichi;
- Nagahori, Masakazu;
- Saito, Eiko;
- Okamoto, Ryuichi;
- Ohtsuka, Kazuo;
- Watanabe, Mamoru
Publication type:
Article
5‐aminosalicylate–intolerant patients are at increased risk of colectomy for ulcerative colitis.
Published in:
Alimentary Pharmacology & Therapeutics, 2021, v. 53, n. 1, p. 103, doi. 10.1111/apt.16120
By:
- Hibiya, Shuji;
- Matsuyama, Yusuke;
- Fujii, Toshimitsu;
- Maeyashiki, Chiaki;
- Saito, Eiko;
- Ito, Kimiko;
- Shimizu, Hiromichi;
- Kawamoto, Ami;
- Motobayashi, Maiko;
- Takenaka, Kento;
- Nagahori, Masakazu;
- Kurosaki, Masayuki;
- Yauchi, Tsunehito;
- Ohtsuka, Kazuo;
- Fujiwara, Takeo;
- Okamoto, Ryuichi;
- Watanabe, Mamoru
Publication type:
Article
Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease.
Published in:
2022
By:
- Hibiya, Shuji;
- Ohtsuka, Kazuo;
- Takenaka, Kento;
- Kawamoto, Ami;
- Matsuyama, Yusuke;
- Udagawa, Yumi;
- Motobayashi, Maiko;
- Shimizu, Hiromichi;
- Fujii, Toshimitsu;
- Saito, Eiko;
- Nagahori, Masakazu;
- Okamoto, Ryuichi;
- Watanabe, Mamoru
Publication type:
journal article
Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus.
Published in:
2021
By:
- Shimizu, Hiromichi;
- Fujii, Toshimitsu;
- Kinoshita, Kenji;
- Kawamoto, Ami;
- Hibiya, Shuji;
- Takenaka, Kento;
- Saito, Eiko;
- Nagahori, Masakazu;
- Ohtsuka, Kazuo;
- Watanabe, Mamoru;
- Okamoto, Ryuichi
Publication type:
journal article
A case of IgG4-related disease associated with ulcerative colitis that was successfully treated with a JAK inhibitor.
Published in:
Modern Rheumatology Case Reports, 2024, v. 8, n. 2, p. 339, doi. 10.1093/mrcr/rxae025
By:
- Tomonao Tanaka;
- Satsuki Aochi;
- Masaaki Uehara;
- Hiromichi Shimizu;
- Motohisa Yamamoto
Publication type:
Article
PGE<sub>2</sub> is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.
Published in:
Scientific Reports, 2016, p. 36795, doi. 10.1038/srep36795
By:
- Fujii, Satoru;
- Suzuki, Kohei;
- Kawamoto, Ami;
- Ishibashi, Fumiaki;
- Nakata, Toru;
- Murano, Tatsuro;
- Ito, Go;
- Shimizu, Hiromichi;
- Mizutani, Tomohiro;
- Oshima, Shigeru;
- Tsuchiya, Kiichiro;
- Nakamura, Tetsuya;
- Araki, Akihiro;
- Ohtsuka, Kazuo;
- Okamoto, Ryuichi;
- Watanabe, Mamoru
Publication type:
Article
Lineage-Specific Expression of Bestrophin-2 and Bestrophin-4 in Human Intestinal Epithelial Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079693
By:
- Ito, Go;
- Okamoto, Ryuichi;
- Murano, Tatsuro;
- Shimizu, Hiromichi;
- Fujii, Satoru;
- Nakata, Toru;
- Mizutani, Tomohiro;
- Yui, Shiro;
- Akiyama-Morio, Junko;
- Nemoto, Yasuhiro;
- Okada, Eriko;
- Araki, Akihiro;
- Ohtsuka, Kazuo;
- Tsuchiya, Kiichiro;
- Nakamura, Tetsuya;
- Watanabe, Mamoru
Publication type:
Article
Long-term efficacy and safety of tofacitinib in patients with ulcerative colitis: 3-year results from a real-world study.
Published in:
Intestinal Research, 2024, v. 22, n. 3, p. 369, doi. 10.5217/ir.2023.00194
By:
- Shimizu, Hiromichi;
- Aonuma, Yuko;
- Hibiya, Shuji;
- Kawamoto, Ami;
- Takenaka, Kento;
- Fujii, Toshimitsu;
- Saito, Eiko;
- Nagahori, Masakazu;
- Ohtsuka, Kazuo;
- Okamoto, Ryuichi
Publication type:
Article
Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn's disease activity confirmed by balloon-assisted enteroscopy.
Published in:
Intestinal Research, 2024, v. 22, n. 1, p. 65, doi. 10.5217/ir.2023.00092
By:
- Ami Kawamoto;
- Kento Takenaka;
- Shuji Hibiya;
- Yoshio Kitazume;
- Hiromichi Shimizu;
- Toshimitsu Fujii;
- Eiko Saito;
- Kazuo Ohtsuka;
- Ryuichi Okamoto
Publication type:
Article
Rapid prediction of 1-year efficacy of tofacitinib for treating refractory ulcerative colitis.
Published in:
Intestinal Research, 2021, v. 19, n. 1, p. 115, doi. 10.5217/ir.2020.00030
By:
- Hiromichi Shimizu;
- Toshimitsu Fujii;
- Shuji Hibiya;
- Maiko Motobayashi;
- Kohei Suzuki;
- Kento Takenaka;
- Eiko Saito;
- Masakazu Nagahori;
- Kazuo Ohtsuka;
- Mamoru Watanabe
Publication type:
Article
Stem cell-based therapy for inflammatory bowel disease.
Published in:
Intestinal Research, 2019, v. 17, n. 3, p. 311, doi. 10.5217/ir.2019.00043
By:
- Hiromichi Shimizu;
- Kohei Suzuki;
- Mamoru Watanabe;
- Ryuichi Okamoto
Publication type:
Article
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation.
Published in:
Inflammation & Regeneration, 2022, v. 42, n. 1, p. 1, doi. 10.1186/s41232-022-00237-3
By:
- Kobayashi, Sakurako;
- Ogasawara, Nobuhiko;
- Watanabe, Satoshi;
- Yoneyama, Yosuke;
- Kirino, Sakura;
- Hiraguri, Yui;
- Inoue, Masami;
- Nagata, Sayaka;
- Okamoto-Uchida, Yoshimi;
- Kofuji, Satoshi;
- Shimizu, Hiromichi;
- Ito, Go;
- Mizutani, Tomohiro;
- Yamauchi, Shinichi;
- Kinugasa, Yusuke;
- Kano, Yoshihito;
- Nemoto, Yasuhiro;
- Watanabe, Mamoru;
- Tsuchiya, Kiichiro;
- Nishina, Hiroshi
Publication type:
Article
Development and Application of Regenerative Medicine in Inflammatory Bowel Disease.
Published in:
Digestion, 2023, v. 104, n. 1, p. 24, doi. 10.1159/000527423
By:
- Okamoto, Ryuichi;
- Mizutani, Tomohiro;
- Shimizu, Hiromichi
Publication type:
Article
Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment.
Published in:
Journal of Gastroenterology, 2023, v. 58, n. 4, p. 379, doi. 10.1007/s00535-023-01959-y
By:
- Watanabe, Satoshi;
- Ogasawara, Nobuhiko;
- Kobayashi, Sakurako;
- Kirino, Sakura;
- Inoue, Masami;
- Hiraguri, Yui;
- Nagata, Sayaka;
- Shimizu, Hiromichi;
- Ito, Go;
- Mizutani, Tomohiro;
- Nemoto, Yasuhiro;
- Tsuchiya, Kiichiro;
- Okamoto, Ryuichi;
- Watanabe, Mamoru;
- Yui, Shiro
Publication type:
Article
Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.
Published in:
2018
By:
- Suzuki, Kohei;
- Murano, Tatsuro;
- Shimizu, Hiromichi;
- Ito, Go;
- Nakata, Toru;
- Fujii, Satoru;
- Ishibashi, Fumiaki;
- Kawamoto, Ami;
- Anzai, Sho;
- Kuno, Reiko;
- Kuwabara, Konomi;
- Takahashi, Junichi;
- Hama, Minami;
- Nagata, Sayaka;
- Hiraguri, Yui;
- Takenaka, Kento;
- Yui, Shiro;
- Tsuchiya, Kiichiro;
- Nakamura, Tetsuya;
- Ohtsuka, Kazuo
Publication type:
journal article
Transmural Remission Characterized by High Biologic Concentrations Demonstrates Better Prognosis in Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2023, v. 17, n. 6, p. 855, doi. 10.1093/ecco-jcc/jjac185
By:
- Takenaka, Kento;
- Kawamoto, Ami;
- Kitazume, Yoshio;
- Fujii, Toshimitsu;
- Udagawa, Yumi;
- Shimizu, Hiromichi;
- Hibiya, Shuji;
- Nagahori, Masakazu;
- Ohtsuka, Kazuo;
- Watanabe, Mamoru;
- Okamoto, Ryuichi
Publication type:
Article
Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients.
Published in:
Journal of Crohn's & Colitis, 2019, v. 13, n. 4, p. 495, doi. 10.1093/ecco-jcc/jjy180
By:
- Kawamoto, Ami;
- Nagata, Sayaka;
- Anzai, Sho;
- Takahashi, Junichi;
- Kawai, Mao;
- Hama, Minami;
- Nogawa, Daichi;
- Yamamoto, Kouhei;
- Kuno, Reiko;
- Suzuki, Kohei;
- Shimizu, Hiromichi;
- Hiraguri, Yui;
- Yui, Shiro;
- Oshima, Shigeru;
- Tsuchiya, Kiichiro;
- Nakamura, Tetsuya;
- Ohtsuka, Kazuo;
- Kitagawa, Masanobu;
- Okamoto, Ryuichi;
- Watanabe, Mamoru
Publication type:
Article

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