Works by Shima, Yoshihito

Results: 35

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for the treatment of autoimmune disorders.

Published in:

Drug Development Research, 2011, v. 72, n. 8, p. 717, doi. 10.1002/ddr.20480

By:

Tanaka, Toshio;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Ogata, Atsushi;
Kumanogoh, Atsushi

Publication type:

Article

Drug‐induced interstitial pneumonia after intravesical Bacillus Calmette‐Guerin administration for bladder cancer with scleroderma.

Published in:

2023

By:

Yoshioka, Fumie;
Kato, Taigo;
Shima, Yoshihito;
Hatano, Koji;
Kawashima, Atsunari;
Fukuhara, Shinichiro;
Imamura, Ryoichi;
Nonomura, Norio

Publication type:

Case Study

Successful treatment of acquired hemophilia A, complicated by chronic GVHD, with tocilizumab.

Published in:

Modern Rheumatology, 2011, v. 21, n. 4, p. 420, doi. 10.3109/s10165-010-0411-6

By:

Nishida, Sumiyuki;
Kawasaki, Tomio;
Kashiwagi, Hirokazu;
Morishima, Atsuyoshi;
Hishitani, Yoshihiro;
Kawai, Mari;
Hirano, Toru;
Ishii, Taeko;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Ogata, Atsushi;
Oka, Yoshihiro;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Article

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, ameliorated clinical symptoms and MRI findings of a patient with ankylosing spondylitis.

Published in:

Modern Rheumatology, 2011, v. 21, n. 4, p. 436, doi. 10.3109/s10165-011-0416-9

By:

Shima, Yoshihito;
Tomita, Tetsuya;
Ishii, Taeko;
Morishima, Atsuyoshi;
Maeda, Yuichi;
Ogata, Atsushi;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Article

Minimal influence of tocilizumab on IFN-γ synthesis by tuberculosis antigens.

Published in:

Modern Rheumatology, 2010, v. 20, n. 2, p. 130, doi. 10.3109/s10165-009-0243-4

By:

Ogata, Atsushi;
Mori, Masahide;
Hashimoto, Shoji;
Yano, Yukihiro;
Fujikawa, Takeya;
Kawai, Mari;
Kuwahara, Yusuke;
Hirano, Toru;
Arimitsu, Junsuke;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Yokota, Souichirou;
Kishimoto, Tadamitsu;
Kawase, Ichiro;
Tanaka, Toshio

Publication type:

Article

Imatinib mesylate inhibited rat adjuvant arthritis and PDGF-dependent growth of synovial fibroblast via interference with the Akt signaling pathway.

Published in:

Modern Rheumatology, 2009, v. 19, n. 5, p. 522, doi. 10.3109/s10165-009-0193-x

By:

Terabe, Fumitaka;
Kitano, Masayasu;
Kawai, Mari;
Kuwahara, Yusuke;
Hirano, Toru;
Arimitsu, Junsuke;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Tanaka, Toshio;
Kawase, Ichiro;
Sano, Hajime;
Ogata, Atsushi

Publication type:

Article

A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus.

Published in:

Modern Rheumatology, 2007, v. 17, n. 3, p. 191, doi. 10.3109/s10165-007-0565-z

By:

Tanaka, Yoshiya;
Yamamoto, Kazuhiko;
Takeuchi, Tsutomu;
Nishimoto, Norihiro;
Miyasaka, Nobuyuki;
Sumida, Takayuki;
Shima, Yoshihito;
Takada, Kazuki;
Matsumoto, Isao;
Saito, Kazuyoshi;
Koike, Takao

Publication type:

Article

The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162306

By:

Morita, Takayoshi;
Shima, Yoshihito;
Wing, James Badger;
Sakaguchi, Shimon;
Ogata, Atsushi;
Kumanogoh, Atsushi

Publication type:

Article

Proteomics-based identification of α-enolase as a tumor antigen in non-small lung cancer.

Published in:

Cancer Science, 2007, v. 98, n. 8, p. 1234, doi. 10.1111/j.1349-7006.2007.00509.x

By:

He, Ping;
Naka, Tetsuji;
Serada, Satoshi;
Fujimoto, Minoru;
Tanaka, Toshio;
Hashimoto, Shoji;
Shima, Yoshihito;
Yamadori, Tomoki;
Suzuki, Hidekazu;
Hirashima, Tomonori;
Matsui, Kaoru;
Shiono, Hiroyuki;
Okumura, Meinoshin;
Nishida, Toshiro;
Tachibana, Isao;
Norioka, Naoko;
Norioka, Shigemi;
Kawase, Ichiro

Publication type:

Article

Recovery from prolonged thrombocytopenia in patients with TAFRO syndrome: case series and literature review.

Published in:

Modern Rheumatology Case Reports, 2020, v. 4, n. 2, p. 302, doi. 10.1080/24725625.2020.1717747

By:

Yamaguchi, Yuta;
Maeda, Yuichi;
Shibahara, Takayuki;
Nameki, Shinichiro;
Nakabayashi, Akihiko;
Komuta, Kiyohide;
Mizuno, Yumiko;
Yagita, Mayu;
Manabe, Yusuke;
Morita, Takayoshi;
Nishide, Masayuki;
Watanabe, Akane;
Takamatsu, Hyota;
Nishida, Sumiyuki;
Hirano, Toru;
Shima, Yoshihito;
Narazaki, Masashi;
Kumanogoh, Atsushi

Publication type:

Article

The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus.

Published in:

International Immunology, 2023, v. 35, n. 1, p. 27, doi. 10.1093/intimm/dxac042

By:

Kajihara, Akiko;
Morita, Takayoshi;
Kato, Yasuhiro;
Konaka, Hachiro;
Murakami, Teruaki;
Yamaguchi, Yuta;
Koyama, Shohei;
Takamatsu, Hyota;
Nishide, Masayuki;
Maeda, Yuichi;
Watanabe, Akane;
Nishida, Sumiyuki;
Hirano, Toru;
Shima, Yoshihito;
Narazaki, Masashi;
Kumanogoh, Atsushi

Publication type:

Article

Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis.

Published in:

International Immunology, 2019, v. 31, n. 5, p. 277, doi. 10.1093/intimm/dxz009

By:

Morita, Takayoshi;
Shima, Yoshihito;
Fujimoto, Kosuke;
Tsuboi, Hideki;
Saeki, Yukihiko;
Narazaki, Masashi;
Ogata, Atsushi;
Kumanogoh, Atsushi

Publication type:

Article

Extensive RNA editing and possible double-stranded structures determining editing sites in the atpB transcripts of hornwort chloroplasts.

Published in:

Nucleic Acids Research, 1997, v. 25, n. 23, p. 4830, doi. 10.1093/nar/25.23.4830

By:

Yoshinaga, Koichi;
Kakehi, Takayuki;
Shima, Yoshihito;
Iinuma, Hiroe;
Masuzawa, Takehiro;
Ueno, Masaru

Publication type:

Article

Effect of Enzymatically Modified Isoquercitrin, a Flavonoid, on Symptoms of Japanese Cedar Pollinosis: A Randomized Double-Blind Placebo-Controlled Trial.

Published in:

International Archives of Allergy & Immunology, 2009, v. 149, n. 4, p. 359, doi. 10.1159/000205582

By:

Kawai, Mari;
Hirano, Toru;
Arimitsu, Junsuke;
Higa, Shinji;
Kuwahara, Yusuke;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Ogata, Atsushi;
Koyanagi, Mihoko;
Kai, Tomoko;
Shimizu, Ryosuke;
Moriwaki, Masamitsu;
Suzuki, Yukio;
Ogino, Satoshi;
Kawase, Ichiro;
Tanaka, Toshio

Publication type:

Article

Luteolin, a Flavonoid, Inhibits CD40 Ligand Expression by Activated Human Basophils.

Published in:

International Archives of Allergy & Immunology, 2006, v. 140, n. 2, p. 150, doi. 10.1159/000092554

By:

Hirano, Toru;
Arimitsu, Junsuke;
Higa, Shinji;
Naka, Tetsuji;
Ogata, Atsushi;
Shima, Yoshihito;
Fujimoto, Minoru;
Yamadori, Tomoki;
Ohkawara, Tomoharu;
Kuwabara, Yusuke;
Kawai, Mari;
Kawase, Ichiro;
Tanaka, Toshio

Publication type:

Article

Flavonoids such as Luteolin, Fisetin and Apigenin Are Inhibitors of Interleukin-4 and Interleukin-13 Production by ActivatedHuman Basophils.

Published in:

International Archives of Allergy & Immunology, 2004, v. 134, n. 2, p. 135, doi. 10.1159/000078498

By:

Hirano, Toru;
Higa, Shinji;
Arimitsu, Junsuke;
Naka, Tetsuji;
Shima, Yoshihito;
Ohshima, Shiro;
Fujimoto, Minoru;
Yamadori, Tomoki;
Kawase, Ichiro;
Tanaka, Toshio

Publication type:

Article

Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis.

Published in:

Rheumatology & Therapy, 2025, v. 12, n. 2, p. 297, doi. 10.1007/s40744-025-00745-x

By:

Shima, Yoshihito;
Uchida-Yamada, Mona;
Motegi, Sei-ichiro;
Shimada, Taku;
Ishii, Haruka;
Ohya, Yoshito;
Kanai, Yasumasa

Publication type:

Article

LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.

Published in:

Scientific Reports, 2016, p. 25738, doi. 10.1038/srep25738

By:

Morimoto, Keiko;
Baba, Yoshihiro;
Shinohara, Hisaaki;
Kang, Sujin;
Nojima, Satoshi;
Kimura, Tetsuya;
Ito, Daisuke;
Yoshida, Yuji;
Maeda, Yohei;
Sarashina-Kida, Hana;
Nishide, Masayuki;
Hosokawa, Takashi;
Kato, Yasuhiro;
Hayama, Yoshitomo;
Kinehara, Yuhei;
Okuno, Tatsusada;
Takamatsu, Hyota;
Hirano, Toru;
Shima, Yoshihito;
Narazaki, Masashi

Publication type:

Article

Cytokines Involved in the Pathogenesis of SSc and Problems in the Development of Anti-Cytokine Therapy.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1104, doi. 10.3390/cells10051104

By:

Shima, Yoshihito;
Bank, Ilan

Publication type:

Article

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.

Published in:

Rheumatology, 2023, v. 62, n. 5, p. 1988, doi. 10.1093/rheumatology/keac528

By:

Itotagawa, Eri;
Tomofuji, Yoshihiko;
Kato, Yasuhiro;
Konaka, Hachiro;
Tsujimoto, Kohei;
Park, JeongHoon;
Nagira, Daiki;
Hirayama, Takehiro;
Jo, Tatsunori;
Hirano, Toru;
Morita, Takayoshi;
Nishide, Masayuki;
Nishida, Sumiyuki;
Shima, Yoshihito;
Narazaki, Masashi;
Okada, Yukinori;
Takamatsu, Hyota;
Kumanogoh, Atsushi

Publication type:

Article

Therapeutic effect of tocilizumab on two patients with polymyositis.

Published in:

2011

By:

Narazaki, Masashi;
Hagihara, Keisuke;
Shima, Yoshihito;
Ogata, Atsushi;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Journal Article

Therapeutic effect of tocilizumab on two patients with polymyositis.

Published in:

2011

By:

Narazaki, Masashi;
Hagihara, Keisuke;
Shima, Yoshihito;
Ogata, Atsushi;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Letter

The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.

Published in:

Rheumatology, 2010, v. 49, n. 12, p. 2408, doi. 10.1093/rheumatology/keq275

By:

Shima, Yoshihito;
Kuwahara, Yusuke;
Murota, Hiroyuki;
Kitaba, Shun;
Kawai, Mari;
Hirano, Toru;
Arimitsu, Junsuke;
Narazaki, Masashi;
Hagihara, Keisuke;
Ogata, Atsushi;
Katayama, Ichiro;
Kawase, Ichiro;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Article

Treatment of a patient with remitting seronegative, symmetrical synovitis with pitting oedema with a humanized anti-interleukin-6 receptor antibody, tocilizumab.

Published in:

2010

By:

Tanaka, Toshio;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Ogata, Atsushi;
Kawase, Ichiro;
Kishimoto, Tadamitsu

Publication type:

Letter

Heating of the neck or elbows alleviates Raynaud's phenomenon but has different effects on different types of patients with systemic sclerosis.

Published in:

Modern Rheumatology, 2024, v. 34, n. 4, p. 750, doi. 10.1093/mr/road091

By:

Yoshihito Shima;
Akane Watanabe;
Nobuto Inoue;
Tetsuya Maruyama;
Eiji Kunitomo;
Atsushi Kumanogoh

Publication type:

Article

Efficacy and safety of tocilizumab in Japanese patients with systemic sclerosis and associated interstitial lung disease: A subgroup analysis of a global, randomised, controlled Phase 3 trial.

Published in:

Modern Rheumatology, 2024, v. 34, n. 3, p. 530, doi. 10.1093/mr/road068

By:

Kuwana, Masataka;
Takehara, Kazuhiko;
Tanaka, Yoshiya;
Yamashita, Katsuhisa;
Katsumata, Kyoko;
Takata, Mai;
Shima, Yoshihito

Publication type:

Article

Arm heating to relieve Raynaud's phenomenon in systemic sclerosis: A single-arm multicentre prospective clinical trial.

Published in:

Modern Rheumatology, 2023, v. 33, n. 5, p. 968, doi. 10.1093/mr/roac116

By:

Watanabe, Akane;
Shima, Yoshihito;
Takahashi, Hiroki;
Akiyama, Yuji;
Kodera, Masanari;
Jinnin, Masatoshi;
Azuma, Naoto;
Ishii, Koji;
Kumanogoh, Atsushi

Publication type:

Article

Proximal heat stress up-regulates angiopoietin-1 in fingers and reduces the severity of Raynaud's phenomenon in systemic sclerosis: a single-centre pilot study.

Published in:

Modern Rheumatology, 2022, v. 32, n. 2, p. 351, doi. 10.1093/mr/roab014

By:

Yoshihito Shima;
Akane Watanabe;
Nobuto Inoue;
Tetsuya Maruyama;
Eiji Kunitomo;
Kunihiko Hamano;
Takashi Kawanishi;
Masashi Takasugi;
Atsushi Kumanogoh

Publication type:

Article

The benefits and prospects of interleukin-6 inhibitor on systemic sclerosis.

Published in:

Modern Rheumatology, 2019, v. 29, n. 2, p. 294, doi. 10.1080/14397595.2018.1559909

By:

Yoshihito Shima

Publication type:

Article

Add-on tocilizumab versus conventional treatment for systemic sclerosis, and cytokine analysis to identify an endotype to tocilizumab therapy.

Published in:

Modern Rheumatology, 2019, v. 29, n. 1, p. 134, doi. 10.1080/14397595.2018.1452178

By:

Yoshihito Shima;
Yasushi Kawaguchi;
Masataka Kuwana

Publication type:

Article

Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.

Published in:

Modern Rheumatology, 2015, v. 25, n. 1, p. 134, doi. 10.3109/14397595.2013.874749

By:

Shima, Yoshihito;
Hosen, Naoki;
Hirano, Toru;
Arimitsu, Junsuke;
Nishida, Sumiyuki;
Hagihara, Keisuke;
Narazaki, Masashi;
Ogata, Atsushi;
Tanaka, Toshio;
Kishimoto, Tadamitsu;
Kumanogoh, Atsushi

Publication type:

Article

Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.

Published in:

Modern Rheumatology, 2013, v. 23, n. 2, p. 1, doi. 10.1007/s10165-013-0855-6

By:

Shima, Yoshihito;
Hosen, Naoki;
Hirano, Toru;
Arimitsu, Junsuke;
Nishida, Sumiyuki;
Hagihara, Keisuke;
Narazaki, Masashi;
Ogata, Atsushi;
Tanaka, Toshio;
Kishimoto, Tadamitsu;
Kumanogoh, Atsushi

Publication type:

Article

A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab.

Published in:

Modern Rheumatology, 2012, v. 22, n. 2, p. 298, doi. 10.3109/s10165-011-0497-5

By:

Hirano, Toru;
Ohguro, Nobuyuki;
Hohki, Satoshi;
Hagihara, Keisuke;
Shima, Yoshihito;
Narazaki, Masashi;
Ogata, Atsushi;
Yoshizaki, Kazuyuki;
Kumanogoh, Atsushi;
Kishimoto, Tadamitsu;
Tanaka, Toshio

Publication type:

Article

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.

Published in:

Arthritis & Rheumatology, 2015, v. 67, n. 6, p. 1481, doi. 10.1002/art.39086

By:

Yoshida, Yuji;
Ogata, Atsushi;
Kang, Sujin;
Ebina, Kousuke;
Shi, Kenrin;
Nojima, Satoshi;
Kimura, Tetsuya;
Ito, Daisuke;
Morimoto, Keiko;
Nishide, Masayuki;
Hosokawa, Takashi;
Hirano, Toru;
Shima, Yoshihito;
Narazaki, Masashi;
Tsuboi, Hideki;
Saeki, Yukihiko;
Tomita, Tetsuya;
Tanaka, Toshio;
Kumanogoh, Atsushi

Publication type:

Article

Fas Antigen/APO-1 (CD95) Expression on Myeloma Cells.

Published in:

Leukemia & Lymphoma, 1996, v. 23, n. 5/6, p. 521, doi. 10.3109/10428199609054860

By:

Shima, Yoshihito;
Nishimoto, Norihiro;
Yoshizaki, Kazuyuki;
Kishimoto, Tadamitsu

Publication type:

Article