Works by Shima, Toshihide

Results: 51
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    Clinicopathological features of liver injury in patients with type 2 diabetes mellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus.

    Published in:
    Journal of Gastroenterology, 2013, v. 48, n. 4, p. 515, doi. 10.1007/s00535-012-0653-5
    By:
    • Shima, Toshihide;
    • Uto, Hirofumi;
    • Ueki, Kohjiro;
    • Takamura, Toshinari;
    • Kohgo, Yutaka;
    • Kawata, Sumio;
    • Yasui, Kohichiroh;
    • Park, Hyohun;
    • Nakamura, Naoto;
    • Nakatou, Tatsuaki;
    • Tanaka, Nobuyoshi;
    • Umemura, Atsushi;
    • Mizuno, Masayuki;
    • Tanaka, Junko;
    • Okanoue, Takeshi
    Publication type:
    Article
    4

    Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease.

    Published in:
    Journal of Gastroenterology, 2011, v. 46, n. 1, p. 101, doi. 10.1007/s00535-010-0291-8
    By:
    • Park, Hyohun;
    • Shima, Toshihide;
    • Yamaguchi, Kanji;
    • Mitsuyoshi, Hironori;
    • Minami, Masahito;
    • Yasui, Kohichiroh;
    • Itoh, Yoshito;
    • Yoshikawa, Toshikazu;
    • Fukui, Michiaki;
    • Hasegawa, Goji;
    • Nakamura, Naoto;
    • Ohta, Mitsuhiro;
    • Obayashi, Hiroshi;
    • Okanoue, Takeshi
    Publication type:
    Article
    5

    Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty liver disease.

    Published in:
    Journal of Gastroenterology, 2010, v. 45, n. 4, p. 426, doi. 10.1007/s00535-009-0154-3
    By:
    • Park, Hyohun;
    • Ishigami, Akihito;
    • Shima, Toshihide;
    • Mizuno, Masayuki;
    • Maruyama, Naoki;
    • Yamaguchi, Kanji;
    • Mitsuyoshi, Hironori;
    • Minami, Masahito;
    • Yasui, Kohichiroh;
    • Itoh, Yoshito;
    • Yoshikawa, Toshikazu;
    • Fukui, Michiaki;
    • Hasegawa, Goji;
    • Nakamura, Naoto;
    • Ohta, Mitsuhiro;
    • Obayashi, Hiroshi;
    • Okanoue, Takeshi
    Publication type:
    Article
    6

    Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.

    Published in:
    PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0185490
    By:
    • Kawaguchi, Takahisa;
    • Shima, Toshihide;
    • Mizuno, Masayuki;
    • Mitsumoto, Yasuhide;
    • Umemura, Atsushi;
    • Kanbara, Yoshihiro;
    • Tanaka, Saiyu;
    • Sumida, Yoshio;
    • Yasui, Kohichiro;
    • Takahashi, Meiko;
    • Matsuo, Keitaro;
    • Itoh, Yoshito;
    • Tokushige, Katsutoshi;
    • Hashimoto, Etsuko;
    • Kiyosawa, Kendo;
    • Kawaguchi, Masanori;
    • Itoh, Hiroyuki;
    • Uto, Hirofumi;
    • Komorizono, Yasuji;
    • Shirabe, Ken
    Publication type:
    Article
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    Trends and Efficacy of Interferon-Free Anti–hepatitis C Virus Therapy in the Region of High Prevalence of Elderly Patients, Cirrhosis, and Hepatocellular Carcinoma: A Real-World, Nationwide, Multicenter Study of 10 688 Patients in Japan.

    Published in:
    Open Forum Infectious Diseases, 2019, v. 6, n. 5, p. N.PAG, doi. 10.1093/ofid/ofz185
    By:
    • Toyoda, Hidenori;
    • Atsukawa, Masanori;
    • Uojima, Haruki;
    • Nozaki, Akito;
    • Tamai, Hideyuki;
    • Takaguchi, Koichi;
    • Fujioka, Shinichi;
    • Nakamuta, Makoto;
    • Tada, Toshifumi;
    • Yasuda, Satoshi;
    • Chuma, Makoto;
    • Senoh, Tomonori;
    • Tsutsui, Akemi;
    • Yamashita, Naoki;
    • Hiraoka, Atsushi;
    • Michitaka, Kojiro;
    • Shima, Toshihide;
    • Akahane, Takehiro;
    • Itobayashi, Ei;
    • Watanabe, Tsunamasa
    Publication type:
    Article
    9

    The efficacy and safety of glecaprevir plus pibrentasvir in 141 patients with severe renal impairment: a prospective, multicenter study.

    Published in:
    Alimentary Pharmacology & Therapeutics, 2019, v. 49, n. 9, p. 1230, doi. 10.1111/apt.15218
    By:
    • Atsukawa, Masanori;
    • Tsubota, Akihito;
    • Toyoda, Hidenori;
    • Takaguchi, Koichi;
    • Nakamuta, Makoto;
    • Watanabe, Tsunamasa;
    • Michitaka, Kojiro;
    • Ikegami, Tadashi;
    • Nozaki, Akito;
    • Uojima, Haruki;
    • Fukunishi, Shinya;
    • Genda, Takuya;
    • Abe, Hiroshi;
    • Hotta, Naoki;
    • Tsuji, Kunihiko;
    • Ogawa, Chikara;
    • Tachi, Yoshihiko;
    • Shima, Toshihide;
    • Shimada, Noritomo;
    • Kondo, Chisa
    Publication type:
    Article
    10

    Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese.

    Published in:
    PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038322
    By:
    • Kawaguchi, Takahisa;
    • Sumida, Yoshio;
    • Umemura, Atsushi;
    • Matsuo, Keitaro;
    • Takahashi, Meiko;
    • Takamura, Toshinari;
    • Yasui, Kohichiroh;
    • Saibara, Toshiji;
    • Hashimoto, Etsuko;
    • Kawanaka, Miwa;
    • Watanabe, Sumio;
    • Kawata, Sumio;
    • Imai, Yasuharu;
    • Kokubo, Miki;
    • Shima, Toshihide;
    • Park, Hyohun;
    • Tanaka, Hideo;
    • Tajima, Kazuo;
    • Yamada, Ryo;
    • Matsuda, Fumihiko
    Publication type:
    Article
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    Impact of fibrosis on liver‐related event incidence in nonalcoholic fatty liver disease: A multicenter observational study.

    Published in:
    Hepatology Research, 2023, v. 53, n. 12, p. 1169, doi. 10.1111/hepr.13950
    By:
    • Chayama, Kazuaki;
    • Hiramatsu, Akira;
    • Shima, Toshihide;
    • Itoh, Yoshito;
    • Yamaguchi, Kanji;
    • Nakajima, Tomoaki;
    • Hoshikawa, Kyoko;
    • Kawamura, Yusuke;
    • Akuta, Norio;
    • Ito, Kiyoaki;
    • Kawanaka, Miwa;
    • Sakamoto, Michiie;
    • Harada, Kenichi;
    • Goto, Yoshihito;
    • Nakayama, Takeo;
    • Kumada, Hiromitsu;
    • Okanoue, Takeshi
    Publication type:
    Article
    14

    Validation of the utility of Agile scores to identify advanced fibrosis and cirrhosis in Japanese patients with nonalcoholic fatty liver disease.

    Published in:
    Hepatology Research, 2023, v. 53, n. 6, p. 489, doi. 10.1111/hepr.13890
    By:
    • Oeda, Satoshi;
    • Seko, Yuya;
    • Hayashi, Hideki;
    • Arai, Taeang;
    • Iwaki, Michihiro;
    • Yoneda, Masato;
    • Shima, Toshihide;
    • Notsumata, Kazuo;
    • Ikegami, Tadashi;
    • Fujii, Hideki;
    • Toyoda, Hidenori;
    • Miura, Kouichi;
    • Morishita, Asahiro;
    • Kawata, Kazuhito;
    • Tomita, Kengo;
    • Kawanaka, Miwa;
    • Isoda, Hiroshi;
    • Yamaguchi, Kanji;
    • Fukushima, Hideaki;
    • Kamada, Yoshihiro
    Publication type:
    Article
    15

    Diagnostic accuracy of enhanced liver fibrosis test for nonalcoholic steatohepatitis‐related fibrosis: Multicenter study.

    Published in:
    Hepatology Research, 2023, v. 53, n. 4, p. 312, doi. 10.1111/hepr.13871
    By:
    • Seko, Yuya;
    • Takahashi, Hirokazu;
    • Toyoda, Hidenori;
    • Hayashi, Hideki;
    • Yamaguchi, Kanji;
    • Iwaki, Michihiro;
    • Yoneda, Masato;
    • Arai, Taeang;
    • Shima, Toshihide;
    • Fujii, Hideki;
    • Morishita, Asahiro;
    • Kawata, Kazuhito;
    • Tomita, Kengo;
    • Kawanaka, Miwa;
    • Yoshida, Yuichi;
    • Ikegami, Tadashi;
    • Notsumata, Kazuo;
    • Oeda, Satoshi;
    • Kamada, Yoshihiro;
    • Sumida, Yoshio
    Publication type:
    Article
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    Wisteria floribunda agglutinin‐positive Mac‐2 binding protein predicts the development of hepatocellular carcinoma in patients with non‐alcoholic fatty liver disease.

    Published in:
    Hepatology Research, 2018, v. 48, n. 7, p. 521, doi. 10.1111/hepr.13054
    By:
    • Kawanaka, Miwa;
    • Tomiyama, Yasuyuki;
    • Hyogo, Hideyuki;
    • Koda, Masahiko;
    • Shima, Toshihide;
    • Tobita, Hiroshi;
    • Hiramatsu, Akira;
    • Nishino, Ken;
    • Okamoto, Toshiaki;
    • Sato, Shuichi;
    • Hara, Yuichi;
    • Nishina, Sohji;
    • Kawamoto, Hirofumi;
    • Chayama, Kazuaki;
    • Okanoue, Takeshi;
    • Hino, Keisuke
    Publication type:
    Article
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    Long-term follow up of peginterferon-α-2a treatment of hepatitis B e-antigen (HBeAg) positive and HBeAg negative chronic hepatitis B patients in phase II and III studies.

    Published in:
    Hepatology Research, 2016, v. 46, n. 10, p. 992, doi. 10.1111/hepr.12638
    By:
    • Okanoue, Takeshi;
    • Shima, Toshihide;
    • Hasebe, Chitomi;
    • Karino, Yoshiyasu;
    • Imazeki, Fumio;
    • Kumada, Takashi;
    • Minami, Masahito;
    • Imai, Yasuharu;
    • Yoshihara, Harumasa;
    • Mita, Eiji;
    • Morikawa, Teruhisa;
    • Nishiguchi, Shuhei;
    • Kawakami, Yoshiiku;
    • Nomura, Hideyuki;
    • Sakisaka, Shotaro;
    • Kurosaki, Masayuki;
    • Yatsuhashi, Hiroshi;
    • Oketani, Makoto;
    • Kohno, Hiroshi;
    • Masumoto, Akihide
    Publication type:
    Article
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    Efficacy and safety of sorafenib in very elderly patients aged 80 years and older with advanced hepatocellular carcinoma.

    Published in:
    Hepatology Research, 2014, v. 44, n. 13, p. 1329, doi. 10.1111/hepr.12308
    By:
    • Jo, Masayasu;
    • Yasui, Kohichiroh;
    • Kirishima, Toshihiko;
    • Shima, Toshihide;
    • Niimi, Toshihisa;
    • Katayama, Takayuki;
    • Mori, Takahiro;
    • Funaki, Jun;
    • Sumida, Yoshio;
    • Fujii, Hideki;
    • Takami, Shiro;
    • Kimura, Hiroyuki;
    • Mitsumoto, Yasuhide;
    • Minami, Masahito;
    • Yamaguchi, Kanji;
    • Yoshinami, Naomi;
    • Mizuno, Masayuki;
    • Sendo, Rei;
    • Tanaka, Saiyu;
    • Shintani, Hiroyuki
    Publication type:
    Article
    28

    Prediction of a favorable clinical course in hepatitis C virus carriers with persistently normal serum alanine aminotransferase levels: A long-term follow-up study.

    Published in:
    Hepatology Research, 2013, v. 43, n. 5, p. 557, doi. 10.1111/j.1872-034X.2012.01091.x
    By:
    • Nishimura, Takeshi;
    • Yamaguchi, Kanji;
    • Fujii, Hideki;
    • Okada, Yorihisa;
    • Yokomizo, Chihiro;
    • Niimi, Toshihisa;
    • Sumida, Yoshio;
    • Yasui, Kohichiroh;
    • Mitsuyoshi, Hironori;
    • Minami, Masahito;
    • Umemura, Atsushi;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Itoh, Yoshito
    Publication type:
    Article
    29

    Treatment extension may benefit female genotype 1 chronic hepatitis C patients with complete early virological response to peginterferon-alpha-2b and ribavirin combination therapy.

    Published in:
    Hepatology Research, 2012, v. 42, n. 10, p. 966, doi. 10.1111/j.1872-034X.2012.01016.x
    By:
    • Nishimura, Takeshi;
    • Yamaguchi, Kanji;
    • Hashimoto, Hiroaki;
    • Niimi, Toshihisa;
    • Yokomizo, Chihiro;
    • Fujii, Hideki;
    • Minami, Masahito;
    • Sakamoto, Masafumi;
    • Ohnish, Naoki;
    • Nagao, Yasuyuki;
    • Okita, Mika;
    • Umemura, Atsushi;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Itoh, Yoshito
    Publication type:
    Article
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    Hepatic steatosis in chronic hepatitis C patients infected with genotype 2 is associated with insulin resistance, hepatic fibrosis and affects cumulative positivity of serum hepatitis C virus RNA in peginterferon and ribavirin combination therapy.

    Published in:
    Hepatology Research, 2011, v. 41, n. 12, p. 1145, doi. 10.1111/j.1872-034X.2011.00886.x
    By:
    • Itoh, Yoshito;
    • Nishimura, Takeshi;
    • Yamaguchi, Kanji;
    • Yokomizo, Chihiro;
    • Fujii, Hideki;
    • Minami, Masahito;
    • Nagao, Yasuyuki;
    • Sumida, Yoshio;
    • Hashimoto, Hiroaki;
    • Umemura, Atsushi;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Yoshikawa, Toshikazu
    Publication type:
    Article
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    The greater impact of PNPLA3 polymorphism on liver‐related events in Japanese non‐alcoholic fatty liver disease patients: A multicentre cohort study.

    Published in:
    Liver International, 2023, v. 43, n. 10, p. 2210, doi. 10.1111/liv.15678
    By:
    • Seko, Yuya;
    • Yamaguchi, Kanji;
    • Shima, Toshihide;
    • Iwaki, Michihiro;
    • Takahashi, Hirokazu;
    • Kawanaka, Miwa;
    • Tanaka, Saiyu;
    • Mitsumoto, Yasuhide;
    • Yoneda, Masato;
    • Nakajima, Atsushi;
    • Fjellström, Ola;
    • Blau, Jenny E.;
    • Carlsson, Björn;
    • Okanoue, Takeshi;
    • Itoh, Yoshito
    Publication type:
    Article
    35

    Marked heterogeneity in the diagnosis of compensated cirrhosis of patients with chronic hepatitis C virus infection in a real‐world setting: A large, multicenter study from Japan.

    Published in:
    Journal of Gastroenterology & Hepatology, 2020, v. 35, n. 8, p. 1420, doi. 10.1111/jgh.14982
    By:
    • Toyoda, Hidenori;
    • Atsukawa, Masanori;
    • Watanabe, Tsunamasa;
    • Nakamuta, Makoto;
    • Uojima, Haruki;
    • Nozaki, Akito;
    • Takaguchi, Koichi;
    • Fujioka, Shinichi;
    • Iio, Etsuko;
    • Shima, Toshihide;
    • Akahane, Takehiro;
    • Fukunishi, Shinya;
    • Asano, Toru;
    • Michitaka, Kojiro;
    • Tsuji, Kunihiko;
    • Abe, Hiroshi;
    • Mikami, Shigeru;
    • Okubo, Hironao;
    • Okubo, Tomomi;
    • Shimada, Noritomo
    Publication type:
    Article
    36

    Real‐world experience of 12‐week direct‐acting antiviral regimen of glecaprevir and pibrentasvir in patients with chronic hepatitis C virus infection.

    Published in:
    Journal of Gastroenterology & Hepatology, 2020, v. 35, n. 5, p. 855, doi. 10.1111/jgh.14874
    By:
    • Toyoda, Hidenori;
    • Atsukawa, Masanori;
    • Watanabe, Tsunamasa;
    • Nakamuta, Makoto;
    • Uojima, Haruki;
    • Nozaki, Akito;
    • Takaguchi, Koichi;
    • Fujioka, Shinichi;
    • Iio, Etsuko;
    • Shima, Toshihide;
    • Akahane, Takehiro;
    • Fukunishi, Shinya;
    • Asano, Toru;
    • Michitaka, Kojiro;
    • Tsuji, Kunihiko;
    • Abe, Hiroshi;
    • Mikami, Shigeru;
    • Okubo, Hironao;
    • Okubo, Tomomi;
    • Shimada, Noritomo
    Publication type:
    Article
    37

    Honokiol Prevents Non-Alcoholic Steatohepatitis-Induced Liver Cancer via EGFR Degradation through the Glucocorticoid Receptor—MIG6 Axis.

    Published in:
    Cancers, 2021, v. 13, n. 7, p. 1515, doi. 10.3390/cancers13071515
    By:
    • Okuda, Keiichiro;
    • Umemura, Atsushi;
    • Umemura, Shiori;
    • Kataoka, Seita;
    • Taketani, Hiroyoshi;
    • Seko, Yuya;
    • Nishikawa, Taichiro;
    • Yamaguchi, Kanji;
    • Moriguchi, Michihisa;
    • Kanbara, Yoshihiro;
    • Arbiser, Jack L.;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Karin, Michael;
    • Itoh, Yoshito;
    • Timchenko, Nikolai
    Publication type:
    Article
    38

    Early Tumor Shrinkage as a Predictive Factor for Outcomes in Hepatocellular Carcinoma Patients Treated with Lenvatinib: A Multicenter Analysis.

    Published in:
    Cancers, 2020, v. 12, n. 3, p. 754, doi. 10.3390/cancers12030754
    By:
    • Takahashi, Aya;
    • Moriguchi, Michihisa;
    • Seko, Yuya;
    • Shima, Toshihide;
    • Mitsumoto, Yasuhide;
    • Takashima, Hidetaka;
    • Kimura, Hiroyuki;
    • Fujii, Hideki;
    • Ishikawa, Hiroki;
    • Yo, Takaharu;
    • Ishiba, Hiroshi;
    • Morita, Atsuhiro;
    • Jo, Masayasu;
    • Nagao, Yasuyuki;
    • Arai, Masahiro;
    • Hara, Tasuku;
    • Okajima, Akira;
    • Muramatsu, Akira;
    • Yoshinami, Naomi;
    • Nakajima, Tomoki
    Publication type:
    Article
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    Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-β1/SMAD Signaling and Autophagy in Hepatic Stellate Cells.

    Published in:
    International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13354, doi. 10.3390/ijms222413354
    By:
    • Kataoka, Seita;
    • Umemura, Atsushi;
    • Okuda, Keiichiro;
    • Taketani, Hiroyoshi;
    • Seko, Yuya;
    • Nishikawa, Taichiro;
    • Yamaguchi, Kanji;
    • Moriguchi, Michihisa;
    • Kanbara, Yoshihiro;
    • Arbiser, Jack L.;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Itoh, Yoshito
    Publication type:
    Article
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    Enhanced Antitumor Effect in Liver Cancer by Amino Acid Depletion-Induced Oxidative Stress.

    Published in:
    Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.758549
    By:
    • Okuda, Keiichiro;
    • Umemura, Atsushi;
    • Kataoka, Seita;
    • Yano, Kota;
    • Takahashi, Aya;
    • Okishio, Shinya;
    • Taketani, Hiroyoshi;
    • Seko, Yuya;
    • Nishikawa, Taichiro;
    • Yamaguchi, Kanji;
    • Moriguchi, Michihisa;
    • Nakagawa, Hayato;
    • Liu, Yu;
    • Mitsumoto, Yasuhide;
    • Kanbara, Yoshihiro;
    • Shima, Toshihide;
    • Okanoue, Takeshi;
    • Itoh, Yoshito
    Publication type:
    Article
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    Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan.

    Published in:
    Journal of Gastroenterology, 2021, v. 56, n. 3, p. 261, doi. 10.1007/s00535-020-01754-z
    By:
    • Tateishi, Ryosuke;
    • Matsumura, Takeshi;
    • Okanoue, Takeshi;
    • Shima, Toshihide;
    • Uchino, Koji;
    • Fujiwara, Naoto;
    • Senokuchi, Takafumi;
    • Kon, Kazuyoshi;
    • Sasako, Takayoshi;
    • Taniai, Makiko;
    • Kawaguchi, Takumi;
    • Inoue, Hiroshi;
    • Watada, Hirotaka;
    • Kubota, Naoto;
    • Shimano, Hitoshi;
    • Kaneko, Shuichi;
    • Hashimoto, Etsuko;
    • Watanabe, Sumio;
    • Shiota, Goshi;
    • Ueki, Kohjiro
    Publication type:
    Article
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    Modified coagulation and clipping method for the prevention of post-operative bleeding after gastric endoscopic submucosal dissection: A multicenter propensity score matching analysis.

    Published in:
    World Academy of Sciences Journal, 2023, v. 5, n. 3, p. 1, doi. 10.3892/wasj.2023.196
    By:
    • KEI TERASAKI;
    • KOTARO OKUDA;
    • KYOKO SAKAI;
    • TAKAO SHIRONO;
    • SHOHEI AMIOKA;
    • TAKAHIRO NONAKA;
    • TAKAHIRO MIURA;
    • NAOTO IWAI;
    • SEIJI FUJINO;
    • HIROHISA OYA;
    • TAKAYUKI KATAYAMA;
    • KIICHIROU MIYAWAKI;
    • TAKASHI OKUDA;
    • JUNKO MATSUMOTO;
    • YASUHIDE MITSUMOTO;
    • CHIEMI MIZUNO;
    • MASAYUKI MIZUNO;
    • SHOJI MITSUFUJI;
    • TOSHIHIDE SHIMA;
    • YOSHITO ITOH
    Publication type:
    Article
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