Works matching AU Shihoya, Wataru

Results: 18

Structural insights into ligand recognition and G protein preferences across histamine receptors.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08363-7

By:

Matsuzaki, Yuma;
Sano, Fumiya K.;
Oshima, Hidetaka S.;
Akasaka, Hiroaki;
Kobayashi, Kazuhiro;
Tanaka, Tatsuki;
Itoh, Yuzuru;
Shihoya, Wataru;
Kise, Yoshiaki;
Kusakizako, Tsukasa;
Inoue, Asuka;
Nureki, Osamu

Publication type:

Article

Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07152-y

By:

Akasaka, Hiroaki;
Sano, Fumiya K.;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58264-w

By:

Saha, Shirsha;
Sano, Fumiya K.;
Sharma, Saloni;
Ganguly, Manisankar;
Dalal, Annu;
Mishra, Sudha;
Tiwari, Divyanshu;
Akasaka, Hiroaki;
Kobayashi, Takaaki A.;
Roy, Nabarun;
Zaidi, Nashrah;
Itoh, Yuzuru;
Leurs, Rob;
Banerjee, Ramanuj;
Shihoya, Wataru;
Nureki, Osamu;
Shukla, Arun K.

Publication type:

Article

Structural insights into the agonist selectivity of the adenosine A3 receptor.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53473-1

By:

Oshima, Hidetaka S.;
Ogawa, Akiko;
Sano, Fumiya K.;
Akasaka, Hiroaki;
Kawakami, Tomoyoshi;
Iwama, Aika;
Okamoto, Hiroyuki H.;
Nagiri, Chisae;
Wei, Fan-Yan;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49030-5

By:

Iwama, Aika;
Kise, Ryoji;
Akasaka, Hiroaki;
Sano, Fumiya K.;
Oshima, Hidetaka S.;
Inoue, Asuka;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Pharmacophore‐guided Virtual Screening to Identify New β3‐adrenergic Receptor Agonists.

Published in:

Molecular Informatics, 2022, v. 41, n. 7, p. 1, doi. 10.1002/minf.202100223

By:

Ujiantari, Navista Sri Octa;
Ham, Seungmin;
Nagiri, Chisae;
Shihoya, Wataru;
Nureki, Osamu;
Hutchinson, Dana Sabine;
Schuster, Daniela

Publication type:

Article

Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0482-7

By:

Nagiri, Chisae;
Shihoya, Wataru;
Inoue, Asuka;
Kadji, Francois Marie Ngako;
Aoki, Junken;
Nureki, Osamu

Publication type:

Article

Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.62389

By:

Kazumasa Oda;
Takashi Nomura;
Takanori Nakane;
Keitaro Yamashita;
Keiichi Inoue;
Shota Ito;
Vierock, Johannes;
Kunio Hirata;
Maturana, Andrés D.;
Kota Katayama;
Tatsuya Ikuta;
Itsuki Ishigami;
Tamaki Izume;
Rie Umeda;
Ryuun Eguma;
Satomi Oishi;
Go Kasuya;
Takafumi Kato;
Tsukasa Kusakizako;
Wataru Shihoya

Publication type:

Article

Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33121-2

By:

Akasaka, Hiroaki;
Tanaka, Tatsuki;
Sano, Fumiya K.;
Matsuzaki, Yuma;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Structural basis for lysophosphatidylserine recognition by GPR34.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45046-z

By:

Izume, Tamaki;
Kawahara, Ryo;
Uwamizu, Akiharu;
Chen, Luying;
Yaginuma, Shun;
Omi, Jumpei;
Kawana, Hiroki;
Hou, Fengjue;
Sano, Fumiya K.;
Tanaka, Tatsuki;
Kobayashi, Kazuhiro;
Okamoto, Hiroyuki H.;
Kise, Yoshiaki;
Ohwada, Tomohiko;
Aoki, Junken;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Cryo-EM advances in GPCR structure determination.

Published in:

Journal of Biochemistry, 2024, v. 176, n. 1, p. 1, doi. 10.1093/jb/mvae029

By:

Shihoya, Wataru;
Iwama, Aika;
Sano, Fumiya K;
Nureki, Osamu

Publication type:

Article

Structural insights into endothelin receptor signalling.

Published in:

Journal of Biochemistry, 2023, v. 174, n. 4, p. 317, doi. 10.1093/jb/mvad055

By:

Shihoya, Wataru;
Sano, Fumiya K;
Nureki, Osamu

Publication type:

Article

Genome-wide CRI SPR screen identifies TMEM41B as a gene required for autophagosome formation.

Published in:

Journal of Cell Biology, 2018, v. 217, n. 11, p. 3817, doi. 10.1083/jcb.201804132

By:

Keigo Morita;
Yutaro Hama;
Tamaki Izume;
Norito Tamura;
Toshihide Ueno;
Yoshihiro Yamashita;
Yuriko Sakamaki;
Kaito Mimura;
Hideaki Morishita;
Wataru Shihoya;
Osamu Nureki;
Hiroyuki Mano;
Noboru Mizushima

Publication type:

Article

Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07094-0

By:

Shihoya, Wataru;
Izume, Tamaki;
Inoue, Asuka;
Yamashita, Keitaro;
Kadji, Francois Marie Ngako;
Hirata, Kunio;
Aoki, Junken;
Nishizawa, Tomohiro;
Nureki, Osamu

Publication type:

Article

Cryo-EM structure of the endothelin-1- ETB- Gi complex.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85821

By:

Sano, Fumiya K.;
Hiroaki Akasaka;
Wataru Shihoya;
Osamu Nureki

Publication type:

Article

Structural insights into the mechanism of rhodopsin phosphodiesterase.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19376-7

By:

Ikuta, Tatsuya;
Shihoya, Wataru;
Sugiura, Masahiro;
Yoshida, Kazuho;
Watari, Masahito;
Tokano, Takaya;
Yamashita, Keitaro;
Katayama, Kota;
Tsunoda, Satoshi P.;
Uchihashi, Takayuki;
Kandori, Hideki;
Nureki, Osamu

Publication type:

Article

Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59299-9

By:

Wang, Yuzhu Z.;
Natsume, Koki;
Tanaka, Tatsuki;
Hososhima, Shoko;
Tashiro, Rintaro;
Sano, Fumiya K.;
Akasaka, Hiroaki;
Tsunoda, Satoshi P.;
Shihoya, Wataru;
Kandori, Hideki;
Nureki, Osamu

Publication type:

Article

Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57960-x

By:

Shihoya, Wataru;
Akasaka, Hiroaki;
Jordan, Peter A.;
Lechner, Anna;
Okada, Bethany K.;
Costa Machado da Cruz, Gabriella;
Sano, Fumiya K.;
Tanaka, Tatsuki;
Kawahara, Ryo;
Chaudhari, Rajan;
Masamune, Hiroko;
Burk, Mark J.;
Nureki, Osamu

Publication type:

Article

Works matching AU Shihoya, Wataru

Structural insights into ligand recognition and G protein preferences across histamine receptors.

Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists.

Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.

Structural insights into the agonist selectivity of the adenosine A<sub>3</sub> receptor.

Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.

Pharmacophore‐guided Virtual Screening to Identify New β<sub>3</sub>‐adrenergic Receptor Agonists.

Crystal structure of human endothelin ET<sub>B</sub> receptor in complex with peptide inverse agonist IRL2500.

Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.

Structure of the active G<sub>i</sub>-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.

Structural basis for lysophosphatidylserine recognition by GPR34.

Cryo-EM advances in GPCR structure determination.

Structural insights into endothelin receptor signalling.

Genome-wide CRI SPR screen identifies TMEM41B as a gene required for autophagosome formation.

Crystal structures of human ET<sub>B</sub> receptor provide mechanistic insight into receptor activation and partial activation.

Cryo-EM structure of the endothelin-1- ET<sub>B</sub>- G<sub>i</sub> complex.

Structural insights into the mechanism of rhodopsin phosphodiesterase.

Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens.

Structure of a lasso peptide bound ET<sub>B</sub> receptor provides insights into the mechanism of GPCR inverse agonism.