Works by Shen, Larry

Results: 20

Plasma Biomarkers, Hippocampal Volume and Cognitive Effects of Oral ALZ‐801: The Phase 2 Biomarker Study and its Long‐Term Extension in APOE4 Carriers with Early Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.092548

By:

Abushakra, Susan;
Hey, John A.;
Blennow, Kaj;
Hort, Jakub;
Prins, Niels D.;
Kesslak, Patrick;
Pak, Winnie;
Shen, Larry;
Zhu, Xinyi;
Li, Caiyan;
Albayrak, Adem;
Bracoud, Luc;
Suhy, Joyce;
Power, Aidan;
Tolar, Martin

Publication type:

Article

Enhanced Weight Loss Following Coadministration of Pramlintide With Sibutramine or Phentermine in a Multicenter Trial.

Published in:

Obesity (19307381), 2010, v. 18, n. 9, p. 1739, doi. 10.1038/oby.2009.478

By:

Aronne, Louis J.;
Halseth, Amy E.;
Burns, Colleen M.;
Miller, Stephan;
Shen, Larry Z.

Publication type:

Article

DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks.

Published in:

2010

By:

Buse JB;
Drucker DJ;
Taylor KL;
Kim T;
Walsh B;
Hu H;
Wilhelm K;
Trautmann M;
Shen LZ;
Porter LE;
DURATION-1 Study Group;
Buse, John B;
Drucker, Daniel J;
Taylor, Kristin L;
Kim, Terri;
Walsh, Brandon;
Hu, Hao;
Wilhelm, Ken;
Trautmann, Michael;
Shen, Larry Z

Publication type:

journal article

DURATION-1. Exenatide Once Weekly Produces Sustained Glycemic Control and Weight Loss Over 52 Weeks.

Published in:

Diabetes Care, 2010, v. 33, n. 6, p. 1255, doi. 10.2337/dc09-1914

By:

Buse, John B.;
Drucker, Daniel J.;
Taylor, Kristin L.;
Kim, Terri;
Walsh, Brandon;
Hu, Hao;
Wilhelm, Ken;
Trautmann, Michael;
Shen, Larry Z.;
Porter, Lisa E.

Publication type:

Article

Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes.

Published in:

2003

By:

Fineman, Mark S.;
Bicsak, Thomas A.;
Shen, Larry Z.;
Taylor, Kristin;
Gaines, Eling;
Varns, Amanda;
Kim, Dennis;
Baron, Alain O.;
Baron, Alain D

Publication type:

journal article

Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial.

Published in:

2003

By:

Hollander, Priscilla A.;
Levy, Philip;
Fineman, Mark S.;
Maggs, David G.;
Shen, Larry Z.;
Strobel, Susan A.;
Weyer, Christian;
Kolterman, Orville G.

Publication type:

journal article

A Randomized Study and Open-Label Extension Evaluating the Long-Term Efficacy of Pramlintide as an Adjunct to Insulin Therapy in Type 1 Diabetes.

Published in:

Diabetes Care, 2002, v. 25, n. 4, p. 724, doi. 10.2337/diacare.25.4.724

By:

Whitehouse, Fred;
Kruger, Davida F.;
Fineman, Mark;
Shen, Larry;
Ruggles, James A.;
Maggs, David G.;
Weyer, Christian;
Kolterman, Orville G.

Publication type:

Article

Properties of pramlintide and insulin upon mixing.

Published in:

American Journal of Health-System Pharmacy, 2005, v. 62, n. 8, p. 816, doi. 10.1093/ajhp/62.8.816

By:

Weyer, Christian;
Fineman, Mark S.;
Strobel, Susan;
Shen, Larry;
Data, Joann;
Kolterman, Orville G.;
Sylvestri, Mario F.

Publication type:

Article

Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus.

Published in:

American Journal of Health-System Pharmacy, 2005, v. 62, n. 2, p. 173., doi. 10.1093/ajhp/62.2.173

By:

Kolterman, Orville G.;
Kim, Dennis D.;
Shen, Larry;
Ruggles, James A.;
Nielsen, Loretta L.;
Fineman, Mark S.;
Baron, Alain D.

Publication type:

Article

Consistency of continual reassessment method under model misspecification.

Published in:

Biometrika, 1996, v. 83, n. 2, p. 395, doi. 10.1093/biomet/83.2.395

By:

SHEN, LARRY Z.;
O'QUIGLEY, JOHN

Publication type:

Article

Effect of Pramlintide on Weight in Overweight and Obese Insulin-Treated Type 2 Diabetes Patients<sup>**</sup>.

Published in:

Obesity (19307381), 2004, v. 12, n. 4, p. 661, doi. 10.1038/oby.2004.76

By:

Hollander, Priscilla;
Maggs, David G.;
Ruggles, James A.;
Fineman, Mark;
Shen, Larry;
Kolterman, Orville G.;
Weyer, Christian

Publication type:

Article

Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes.

Published in:

Diabetes/Metabolism Research & Reviews, 2004, v. 20, n. 5, p. 411, doi. 10.1002/dmrr.499

By:

Fineman, Mark S.;
Shen, Larry Z.;
Taylor, Kristin;
Kim, Dennis D.;
Baron, Alain D.

Publication type:

Article

Sample size determination for controlling the upper confidence limit of incidence rate of a binomial endpoint.

Published in:

Journal of Biopharmaceutical Statistics, 1998, v. 8, n. 3, p. 489, doi. 10.1080/10543409808835254

By:

Shen, Larry Z.

Publication type:

Article

Application of boundary calculation methodologies to group sequential testing in general parametric models.

Published in:

Communications in Statistics: Theory & Methods, 1997, v. 26, n. 9, p. 2173, doi. 10.1080/03610929708832040

By:

Shen, Larry Z.;
Al- Khalidi, Hussein R.

Publication type:

Article

On optimal b-robust influence functions in multidimensional parametric models.

Published in:

Communications in Statistics: Theory & Methods, 1994, v. 23, n. 4, p. 1103, doi. 10.1080/03610929408831307

By:

Zaiqian Shen, Larry

Publication type:

Article

Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QT<sub>c</sub> interval in healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 75, n. 4, p. 979, doi. 10.1111/j.1365-2125.2012.04416.x

By:

Darpö, Börje;
Philip, Sager;
MacConell, Leigh;
Cirincione, Brenda;
Mitchell, Malcolm;
Han, Jenny;
Huang, Wenying;
Malloy, Jaret;
Schulteis, Christine;
Shen, Larry;
Porter, Lisa

Publication type:

Article

Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes.

Published in:

Cardiovascular Diabetology, 2011, v. 10, n. 1, p. 22, doi. 10.1186/1475-2840-10-22

By:

Ratner, Robert;
Han, Jenny;
Nicewarner, Dawn;
Yushmanova, Irina;
Hoogwerf, Byron J.;
Shen, Larry

Publication type:

Article

The Relationship of Pronuclear Stage Morphology and Chromosome Status at Cleavage Stage.

Published in:

Journal of Assisted Reproduction & Genetics, 2003, v. 20, n. 10, p. 413, doi. 10.1023/A:1026232625659

By:

Chun-Kai Chen;
Guan-Yi Shen, Larry I.;
Shang-Gwo Horng;
Chia-Woei Wang;
Hong-Yuan Huang;
Hsin-Shin Wang, Larry I.;
Yung-Kuei Soong

Publication type:

Article

Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease.

Published in:

Drugs, 2024, v. 84, n. 7, p. 811, doi. 10.1007/s40265-024-02067-8

By:

Hey, John A.;
Abushakra, Susan;
Blennow, Kaj;
Reiman, Eric M.;
Hort, Jakub;
Prins, Niels D.;
Sheardova, Katerina;
Kesslak, Patrick;
Shen, Larry;
Zhu, Xinyi;
Albayrak, Adem;
Paul, Jijo;
Schaefer, Jean F.;
Power, Aidan;
Tolar, Martin

Publication type:

Article

CLINICAL EFFECTS OF TRAMIPROSATE IN APOE4 HOMOZYGOTES WITH MILD TO MODERATE ALZHEIMER'S DISEASE (AD) ARE SUSTAINED OVER 130 WEEKS: RESULTS OF A PHASE 3 EXTENSION STUDY.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P256, doi. 10.1016/j.jalz.2017.06.119

By:

Abushakra, Susan;
Sadowsky, Carl H.;
Porsteinsson, Anton P.;
Gauthier, Serge;
Vellas, Bruno;
Power, Aidan;
Shen, Larry;
Wang, Peter;
Hey, John;
Tolar, Martin

Publication type:

Article