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Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model.
Published in:
2018
By:
- Khan, Archie A;
- Shekh‐Ahmad, Tawfeeq;
- Khalil, Ayatakin;
- Walker, Matthew C;
- Ali, Afia B;
- Shekh-Ahmad, Tawfeeq
Publication type:
journal article
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Published in:
2019
By:
- Pauletti, Alberto;
- Terrone, Gaetano;
- Shekh-Ahmad, Tawfeeq;
- Salamone, Alessia;
- Ravizza, Teresa;
- Rizzi, Massimo;
- Pastore, Anna;
- Pascente, Rosaria;
- Liang, Li-Ping;
- Villa, Bianca R;
- Balosso, Silvia;
- Abramov, Andrey Y;
- Vliet, Erwin A van;
- Giudice, Ennio Del;
- Aronica, Eleonora;
- Patel, Manisha;
- Walker, Matthew C;
- Vezzani, Annamaria;
- van Vliet, Erwin A;
- Del Giudice, Ennio
Publication type:
journal article
KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy.
Published in:
2018
By:
- Shekh-Ahmad, Tawfeeq;
- Eckel, Ramona;
- Naidu, Sharadha Dayalan;
- Higgins, Maureen;
- Masayuki Yamamoto;
- Dinkova-Kostova, Albena T.;
- Kovac, Stjepana;
- Abramov, Andrey Y.;
- Walker, Matthew C.;
- Dayalan Naidu, Sharadha;
- Yamamoto, Masayuki
Publication type:
journal article
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Published in:
2017
By:
- Pauletti, Alberto;
- Terrone, Gaetano;
- Shekh-Ahmad, Tawfeeq;
- Salamone, Alessia;
- Ravizza, Teresa;
- Rizzi, Massimo;
- Pastore, Anna;
- Pascente, Rosaria;
- Li-Ping Liang;
- Villa, Bianca R.;
- Balosso, Silvia;
- Abramov, Andrey Y.;
- van Vliet, Erwin A.;
- Del Giudice, Ennio;
- Aronica, Eleonora;
- Antoine, Daniel J.;
- Patel, Manisha;
- Walker, Matthew C.;
- Vezzani, Annamaria;
- Liang, Li-Ping
Publication type:
journal article
sec-Butyl-propylacetamide (SPD) and two of its stereoisomers rapidly terminate paraoxon-induced status epilepticus in rats.
Published in:
Epilepsia (Series 4), 2014, v. 55, n. 12, p. 1953, doi. 10.1111/epi.12838
By:
- Bar‐Klein, Guy;
- Swissa, Evyatar;
- Kamintsky, Lyn;
- Shekh‐Ahmad, Tawfeeq;
- Saar‐Ashkenazy, Rotem;
- Hubary, Yechiel;
- Shrot, Shai;
- Stetlander, Liran;
- Eisenkraft, Arik;
- Friedman, Alon;
- Bialer, Meir
Publication type:
Article
Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
Published in:
Epilepsia (Series 4), 2014, v. 55, n. 12, p. 1944, doi. 10.1111/epi.12857
By:
- Shekh‐Ahmad, Tawfeeq;
- Mawasi, Hafiz;
- McDonough, John H.;
- Finnell, Richard H.;
- Wlodarczyk, Bogdan J.;
- Yavin, Eylon;
- Bialer, Meir
Publication type:
Article
Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
Published in:
Epilepsia (Series 4), 2014, v. 55, n. 2, p. 353, doi. 10.1111/epi.12480
By:
- Shekh-Ahmad, Tawfeeq;
- Hen, Naama;
- Yagen, Boris;
- McDonough, John H.;
- Finnell, Richard H.;
- Wlodarczyk, Bogdan J.;
- Bialer, Meir
Publication type:
Article
Valnoctamide and sec-butyl-propylacetamide ( SPD) for acute seizures and status epilepticus.
Published in:
Epilepsia (Series 4), 2013, v. 54, p. 99, doi. 10.1111/epi.12290
By:
- Shekh‐Ahmad, Tawfeeq;
- Hen, Naama;
- McDonough, John H.;
- Yagen, Boris;
- Bialer, Meir
Publication type:
Article
Comparative steady-state pharmacokinetic evaluation of immediate-release topiramate and USL255, a once-daily extended-release topiramate formulation.
Published in:
Epilepsia (Series 4), 2013, v. 54, n. 8, p. 1444, doi. 10.1111/epi.12225
By:
- Bialer, Meir;
- Shekh‐Ahmad, Tawfeeq;
- Braun, Tricia L.;
- Halvorsen, Mark B.
Publication type:
Article
A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
Published in:
Epilepsia (Series 4), 2012, v. 53, n. 1, p. 134, doi. 10.1111/j.1528-1167.2011.03338.x
By:
- White, H. Steve;
- Alex, Anitha B.;
- Pollock, Amanda;
- Hen, Naama;
- Shekh-Ahmad, Tawfeeq;
- Wilcox, Karen S.;
- McDonough, John H.;
- Stables, James P.;
- Kaufmann, Dan;
- Yagen, Boris;
- Bialer, Meir
Publication type:
Article
Comparative pharmacokinetic analysis of USL255, a new once-daily extended-release formulation of topiramate.
Published in:
Epilepsia (Series 4), 2011, v. 52, n. 10, p. 1877, doi. 10.1111/j.1528-1167.2011.03183.x
By:
- Lambrecht, Lawrence J.;
- Shekh-Ahmad, Tawfeeq;
- Todd, Wesley M.;
- Halvorsen, Mark B.;
- Bialer, Meir
Publication type:
Article
Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy.
Published in:
Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-022-00951-y
By:
- Sandouka, Sereen;
- Saadi, Aseel;
- Singh, Prince Kumar;
- Olowe, Rhoda;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article
N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice.
Published in:
Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02574-4
By:
- Shahen-Zoabi, Samah;
- Smoum, Reem;
- Bingor, Alexey;
- Grad, Etty;
- Nemirovski, Alina;
- Shekh-Ahmad, Tawfeeq;
- Mechoulam, Raphael;
- Yaka, Rami
Publication type:
Article
Nrf2 is expressed more extensively in neurons than in astrocytes following an acute epileptic seizure in rats.
Published in:
Journal of Neurochemistry, 2023, v. 165, n. 4, p. 550, doi. 10.1111/jnc.15786
By:
- Sandouka, Sereen;
- Saadi, Aseel;
- Olowe, Rhoda;
- Singh, Prince Kumar;
- Shekh‐Ahmad, Tawfeeq
Publication type:
Article
Drugs acting at TRPM7 channels inhibit seizure‐like activity.
Published in:
Epilepsia Open, 2023, v. 8, n. 3, p. 1169, doi. 10.1002/epi4.12773
By:
- Khalil, Aytakin;
- Shekh‐Ahmad, Tawfeeq;
- Kovac, Stjepana;
- Wykes, Robert C.;
- Horgen, F. David;
- Fleig, Andrea;
- Walker, Matthew C.
Publication type:
Article
NOX4-derived ROS are neuroprotective by balancing intracellular calcium stores.
Published in:
Cellular & Molecular Life Sciences, 2023, v. 80, n. 5, p. 1, doi. 10.1007/s00018-023-04758-z
By:
- Gola, Lukas;
- Bierhansl, Laura;
- Csatári, Júlia;
- Schroeter, Christina B.;
- Korn, Lisanne;
- Narayanan, Venu;
- Cerina, Manuela;
- Abdolahi, Sara;
- Speicher, Anna;
- Hermann, Alexander M.;
- König, Simone;
- Dinkova-Kostova, Albena T.;
- Shekh-Ahmad, Tawfeeq;
- Meuth, Sven G.;
- Wiendl, Heinz;
- Gorji, Ali;
- Pawlowski, Matthias;
- Kovac, Stjepana
Publication type:
Article
Repurposing dimethyl fumarate as an antiepileptogenic and disease-modifying treatment for drug-resistant epilepsy.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04695-2
By:
- Sandouka, Sereen;
- Singh, Prince Kumar;
- Saadi, Aseel;
- Taiwo, Rhoda Olowe;
- Sheeni, Yara;
- Zhang, Taige;
- Deeb, Larin;
- Guignet, Michelle;
- White, Steve H.;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article
Induction of the Nrf2 Pathway by Sulforaphane Is Neuroprotective in a Rat Temporal Lobe Epilepsy Model.
Published in:
Antioxidants, 2021, v. 10, n. 11, p. 1702, doi. 10.3390/antiox10111702
By:
- Sandouka, Sereen;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article
Approaches for Reactive Oxygen Species and Oxidative Stress Quantification in Epilepsy.
Published in:
Antioxidants, 2020, v. 9, n. 10, p. 990, doi. 10.3390/antiox9100990
By:
- Olowe, Rhoda;
- Sandouka, Sereen;
- Saadi, Aseel;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article
Approaches for Reactive Oxygen Species and Oxidative Stress Quantification in Epilepsy.
Published in:
Antioxidants, 2020, v. 9, n. 10, p. 990, doi. 10.3390/antiox9100990
By:
- Olowe, Rhoda;
- Sandouka, Sereen;
- Saadi, Aseel;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article
A randomized, double-blind, placebo- and risperidone-controlled study on valnoctamide for acute mania.
Published in:
Bipolar Disorders, 2017, v. 19, n. 4, p. 285, doi. 10.1111/bdi.12506
By:
- Weiser, Mark;
- Levi, Linda;
- Levine, Stephen Z;
- Bialer, Meir;
- Shekh‐Ahmad, Tawfeeq;
- Matei, Valentin;
- Tiugan, Alexandru;
- Cirjaliu, Diana;
- Sava, Cristinel;
- Sinita, Eugenia;
- Zamora, Daisy;
- Davis, John M
Publication type:
Article
Epilepsy Gene Therapy Using an Engineered Potassium Channel.
Published in:
Journal of Neuroscience, 2019, v. 39, n. 16, p. 3159, doi. 10.1523/JNEUROSCI.1143-18.2019
By:
- Snowball, Albert;
- Chabrol, Elodie;
- Wykes, Robert C.;
- Shekh-Ahmad, Tawfeeq;
- Cornford, Jonathan H.;
- Lieb, Andreas;
- Hughes, Michael P.;
- Massaro, Giulia;
- Rahim, Ahad A.;
- Hashemi, Kevan S.;
- Kullmann, Dimitri M.;
- Walker, Matthew C.;
- Schorge, Stephanie
Publication type:
Article
Nrf2 as a potential target for the treatment of epilepsy.
Published in:
Neural Regeneration Research, 2024, v. 19, n. 9, p. 1865, doi. 10.4103/1673-5374.390975
By:
- Singh, Prince Kumar;
- Shekh-Ahmad, Tawfeeq
Publication type:
Article

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