Works matching AU Sharp, Swee Y.

Results: 10

Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54356-1

By:

Sharp, Swee Y.;
Martella, Marianna;
D’Agostino, Sabrina;
Milton, Christopher I.;
Ward, George;
Woodhead, Andrew J.;
Richardson, Caroline J.;
Carr, Maria G.;
Chiarparin, Elisabetta;
Cons, Benjamin D.;
Coyle, Joseph;
East, Charlotte E.;
Hiscock, Steven D.;
Martinez-Fleites, Carlos;
Mortenson, Paul N.;
Palmer, Nick;
Pathuri, Puja;
Powers, Marissa V.;
Saalau, Susanne M.;
St. Denis, Jeffrey D.

Publication type:

Article

Effects of HSP90 inhibitor 17-allylamino-17 -demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.

Published in:

BMC Research Notes, 2012, v. 5, n. 1, p. 250, doi. 10.1186/1756-0500-5-250

By:

Rodrigues, Loretta M;
Chung, Yuen-Li;
Al Saffar, Nada M;
Sharp, Swee Y;
Jackson, Laura E;
Banerji, Udai;
Stubbs, Marion;
Leach, Martin O;
Griffiths, John R;
Workman, Paul

Publication type:

Article

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Correction Notice

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A;
Judson, Ian;
Jackman, Ann L;
Workman, Paul

Publication type:

corrected article

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 769, doi. 10.1007/s00280-007-0662-x

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Article

Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71969-w

By:

Darby, John F.;
Vidler, Lewis R.;
Simpson, Peter J.;
Al-Lazikani, Bissan;
Matthews, Stephen J.;
Sharp, Swee Y.;
Pearl, Laurence H.;
Hoelder, Swen;
Workman, Paul

Publication type:

Article

Co-Crystalization and In VitroBiological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044642

By:

Sharp, Swee Y.;
Roe, S. Mark;
Kazlauskas, Egidijus;
Čikotienė, Inga;
Workman, Paul;
Matulis, Daumantas;
Prodromou, Chrisostomos;
Wenqing Xu

Publication type:

Article

Inhibition of Hsp90 with Resorcylic Acid Macrolactones: Synthesis and Binding Studies.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 34, p. 10366, doi. 10.1002/chem.201001119

By:

Day, James E. H.;
Sharp, Swee Y.;
Rowlands, Martin G.;
Aherne, Wynne;
Lewis, William;
Roe, S. Mark;
Prodromou, Chrisostomos;
Pearl, Laurence H.;
Workman, Paul;
Moody, Christopher J.

Publication type:

Article

Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 9, p. 2758, doi. 10.1002/chem.200902766

By:

Day, James E. H.;
Sharp, Swee Y.;
Rowlands, Martin G.;
Aherne, Wynne;
Workman, Paul;
Moody, Christopher J.

Publication type:

Article

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90.

Published in:

1999

By:

Kelland, Lloyd R.;
Sharp, Swee Y.;
Kelland, L R;
Sharp, S Y;
Rogers, P M;
Myers, T G;
Workman, P

Publication type:

journal article