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Riluzole regulates pancreatic cancer cell metabolism by suppressing the Wnt-β-catenin pathway.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13472-y
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- Article
Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms.
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- Molecular Cancer, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-4598-12-171
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- Article
Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells.
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- Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-60
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- Article
Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis.
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- Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-16
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- Article
α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras<sup>G12D</sup>, and Kras<sup>G12D</sup>/tp53R270H) mice.
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- Scientific Reports, 2016, p. 32743, doi. 10.1038/srep32743
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- Article
Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from Kras<sup>G12D</sup> Mice by Inhibiting Akt and Sonic Hedgehog Pathways.
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- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0092161
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- Article
Sonic Hedgehog Signaling Inhibition Provides Opportunities for Targeted Therapy by Sulforaphane in Regulating Pancreatic Cancer Stem Cell Self-Renewal.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046083
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- Article
Expression of MUC17 Is Regulated by HIF1α-Mediated Hypoxic Responses and Requires a Methylation-Free Hypoxia Responsible Element in Pancreatic Cancer.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044108
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- Article
Trichosanthin Inhibits Breast Cancer Cell Proliferation in Both Cell Lines and Nude Mice by Promotion of Apoptosis.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0041592
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- Article
Pristimerin Causes G1 Arrest, Induces Apoptosis, and Enhances the Chemosensitivity to Gemcitabine in Pancreatic Cancer Cells.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043826
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- Article
Withaferin A Inhibits the Proteasome Activity in Mesothelioma In Vitro and In Vivo.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0041214
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- Article
EGCG Enhances the Therapeutic Potential of Gemcitabine and CP690550 by Inhibiting STAT3 Signaling Pathway in Human Pancreatic Cancer.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031067
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- Article
Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027306
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- Article
Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025166
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- Article
Targeting Epigenetic Regulation of miR-34a for Treatment of Pancreatic Cancer by Inhibition of Pancreatic Cancer Stem Cells.
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- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0024099
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- Article
Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and Kras<sup>G12D</sup> Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016530
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- Article
Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor.
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- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015627
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- Article
Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells.
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- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015288
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- Article
HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma.
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- Oncogene, 2005, v. 24, n. 29, p. 4609, doi. 10.1038/sj.onc.1208585
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- Article
NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200.
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- Neuro-Oncology, 2013, v. 15, n. 6, p. 691
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- Article
Inhibition of ribosome assembly factor PNO1 by CRISPR/Cas9 technique suppresses lung adenocarcinoma and Notch pathway: Clinical application.
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- Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 3, p. 365, doi. 10.1111/jcmm.17657
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- Article
Chronic alcohol exposure induces hepatocyte damage by inducing oxidative stress, SATB2 and stem cell‐like characteristics, and activating lipogenesis.
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- Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 7, p. 2119, doi. 10.1111/jcmm.17235
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- Article
Ethanol exposure of human pancreatic normal ductal epithelial cells induces EMT phenotype and enhances pancreatic cancer development in KC (Pdx1‐Cre and LSL‐Kras<sup>G12D</sup>) mice.
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- Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 2, p. 399, doi. 10.1111/jcmm.17092
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- Article
SATB2 is a novel biomarker and therapeutic target for cancer.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 19, p. 11064, doi. 10.1111/jcmm.15755
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- Article
α‐Mangostin‐encapsulated PLGA nanoparticles inhibit colorectal cancer growth by inhibiting Notch pathway.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 19, p. 11343, doi. 10.1111/jcmm.15731
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- Article
The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 14, p. 7706, doi. 10.1111/jcmm.15413
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- Article
Higher expression of SATB2 in hepatocellular carcinoma of African Americans determines more aggressive phenotypes than those of Caucasian Americans.
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- Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 12, p. 7999, doi. 10.1111/jcmm.14652
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- Article
Inhibition of pancreatic cancer stem cell characteristics by α‐Mangostin: Molecular mechanisms involving Sonic hedgehog and Nanog.
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- Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 4, p. 2719, doi. 10.1111/jcmm.14178
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- Article
Chronic ethanol exposure of human pancreatic normal ductal epithelial cells induces cancer stem cell phenotype through SATB2.
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- Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 8, p. 3920, doi. 10.1111/jcmm.13666
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- Article
Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway.
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- Carcinogenesis, 2017, v. 38, n. 10, p. 1047, doi. 10.1093/carcin/bgx070
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- Article
Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.
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- Carcinogenesis, 2007, v. 28, n. 6, p. 1277, doi. 10.1093/carcin/bgm024
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- Article
Clinical significance of PNO1 as a novel biomarker and therapeutic target of hepatocellular carcinoma.
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- Journal of Cellular & Molecular Medicine, 2024, v. 28, n. 9, p. 1, doi. 10.1111/jcmm.18295
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- Article
Inhibition of sonic hedgehog and PI3K/Akt/mTOR pathways cooperate in suppressing survival, self-renewal and tumorigenic potential of glioblastoma-initiating cells.
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- Molecular & Cellular Biochemistry, 2019, v. 454, n. 1/2, p. 11, doi. 10.1007/s11010-018-3448-z
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- Article
Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.
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- Molecular & Cellular Biochemistry, 2013, v. 373, n. 1/2, p. 217, doi. 10.1007/s11010-012-1493-6
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- Article
EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.
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- Molecular & Cellular Biochemistry, 2013, v. 372, n. 1/2, p. 83, doi. 10.1007/s11010-012-1448-y
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- Article
FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol.
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- Molecular & Cellular Biochemistry, 2010, v. 337, n. 1/2, p. 201, doi. 10.1007/s11010-009-0300-5
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- Article
Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.
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- Molecular & Cellular Biochemistry, 2007, v. 304, n. 1/2, p. 273, doi. 10.1007/s11010-007-9510-x
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- Article
Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo.
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- Prostate, 2005, v. 62, n. 2, p. 165, doi. 10.1002/pros.20126
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- Article
Triacetyl resveratrol upregulates miRNA-200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent.
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- International Journal of Oncology, 2019, v. 54, n. 4, p. 1306, doi. 10.3892/ijo.2019.4700
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- Article
Increased Risk of Hepatocellular Carcinoma Associated With Neighborhood Concentrated Disadvantage.
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- Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00375
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- Article
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
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- International Journal of Cancer, 2012, v. 131, n. 1, p. 30, doi. 10.1002/ijc.26323
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- Article
Oncogenic Role of SATB2 In Vitro: Regulator of Pluripotency, Self-Renewal, and Epithelial–Mesenchymal Transition in Prostate Cancer.
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- Cells (2073-4409), 2024, v. 13, n. 11, p. 962, doi. 10.3390/cells13110962
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- Article
Association of Diabetes Mellitus and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance.
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- Cells (2073-4409), 2021, v. 10, n. 11, p. 3077, doi. 10.3390/cells10113077
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- Article
Stem Cells in Neurological Disorders: Emerging Therapy with Stunning Hopes.
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- Molecular Neurobiology, 2015, v. 52, n. 1, p. 610, doi. 10.1007/s12035-014-8883-6
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- Article
Assessment of risk factors, and racial and ethnic differences in hepatocellular carcinoma.
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- JGH Open, 2020, v. 4, n. 3, p. 351, doi. 10.1002/jgh3.12336
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- Article
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.
- Published in:
- Journal of Molecular Signaling, 2010, v. 5, p. 14, doi. 10.1186/1750-2187-5-14
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- Article
Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.
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- Journal of Molecular Signaling, 2010, v. 5, p. 10, doi. 10.1186/1750-2187-5-10
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- Article
Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor.
- Published in:
- Journal of Molecular Signaling, 2008, v. 3, p. 1, doi. 10.1186/1750-2187-3-7
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- Article
Curcumin enhances the apoptosis-inducing potential of TRAIL inprostate cancer cells: molecular mechanisms of apoptosis,migration and angiogenesis.
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- Journal of Molecular Signaling, 2007, v. 2, p. 10, doi. 10.1186/1750-2187-2-10
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- Article
Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential.
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- Journal of Molecular Signaling, 2007, v. 2, p. 7, doi. 10.1186/1750-2187-2-7
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- Article