Works matching AU Shanghai Chen

Results: 36

Deletion of ATF4 in AgRP Neurons Promotes Fat Loss Mainly via Increasing Energy Expenditure.

Published in:

2017

By:

Jiali Deng;
Feixiang Yuan;
Yajie Guo;
Yuzhong Xiao;
Yuguo Niu;
Yalan Deng;
Xiao Han;
Youfei Guan;
Shanghai Chen;
Feifan Guo;
Deng, Jiali;
Yuan, Feixiang;
Guo, Yajie;
Xiao, Yuzhong;
Niu, Yuguo;
Deng, Yalan;
Han, Xiao;
Guan, Youfei;
Chen, Shanghai;
Guo, Feifan

Publication type:

journal article

Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52059-1

By:

Jiang, Xiaoxue;
liu, Kan;
Luo, Peixiang;
Li, Zi;
Xiao, Fei;
Jiang, Haizhou;
Wu, Shangming;
Tang, Min;
Yuan, Feixiang;
Li, Xiaoying;
Shu, Yousheng;
Peng, Bo;
Chen, Shanghai;
Ni, Shihong;
Guo, Feifan

Publication type:

Article

Hepatic cytokine‐inducible SH2‐containing protein (CISH) regulates gluconeogenesis via cAMP‐responsive element binding protein (CREB).

Published in:

FASEB Journal, 2022, v. 36, n. 10, p. 1, doi. 10.1096/fj.202200870R

By:

Xiao, Fei;
Deng, Jiali;
Jiao, Fuxin;
Hu, Xiaoming;
Jiang, Haizhou;
Yuan, Feixiang;
Chen, Shanghai;
Niu, Yuguo;
Jiang, Xiaoxue;
Guo, Feifan

Publication type:

Article

Activation of GCN2 in macrophages promotes white adipose tissue browning and lipolysis under leucine deprivation.

Published in:

FASEB Journal, 2021, v. 35, n. 6, p. 1, doi. 10.1096/fj.202100061RR

By:

Fenfen Wang;
Fei Xiao;
Linjuan Du;
Yuguo Niu;
Hanrui Yin;
Ziheng Zhou;
Xiaoxue Jiang;
Haizhou Jiang;
Feixiang Yuan;
Kan Liu;
Shanghai Chen;
Shengzhong Duan;
Feifan Guo

Publication type:

Article

ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression.

Published in:

Journal of Cellular & Molecular Medicine, 2014, v. 18, n. 1, p. 80, doi. 10.1111/jcmm.12166

By:

Wang, Chunxia;
Li, Houkai;
Meng, Qingshu;
Du, Ying;
Xiao, Fei;
Zhang, Qian;
Yu, Junjie;
Li, Kai;
Chen, Shanghai;
Huang, Zhiying;
Liu, Bin;
Guo, Feifan

Publication type:

Article

Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03609-0

By:

Hu, Xiaoming;
Niu, Yuguo;
Luo, Peixiang;
Xiao, Fei;
Yuan, Feixiang;
Yin, Hanrui;
Chen, Shanghai;
Guo, Feifan

Publication type:

Article

Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38141-0

By:

Xiao, Fei;
Jiang, Haizhou;
Li, Zi;
Jiang, Xiaoxue;
Chen, Shanghai;
Niu, Yuguo;
Yin, Hanrui;
Shu, Yousheng;
Peng, Bo;
Lu, Wei;
Li, Xiaoying;
Li, Zhigang;
Lan, Shujue;
Xu, Xiaoyan;
Guo, Feifan

Publication type:

Article

Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening.

Published in:

Autophagy, 2020, v. 16, n. 3, p. 451, doi. 10.1080/15548627.2019.1628537

By:

Deng, Jiali;
Guo, Yajie;
Yuan, Feixiang;
Chen, Shanghai;
Yin, Hanrui;
Jiang, Xiaoxue;
Jiao, Fuxin;
Wang, Fenfen;
Ji, Hongbin;
Hu, Guohong;
Ying, Hao;
Chen, Yan;
Zhai, Qiwei;
Xiao, Fei;
Guo, Feifan

Publication type:

Article

Intestinal Epithelial Cell-specific Deletion of Cytokine-inducible SH2-containing Protein Alleviates Experimental Colitis in Ageing Mice.

Published in:

Journal of Crohn's & Colitis, 2023, v. 17, n. 8, p. 1278, doi. 10.1093/ecco-jcc/jjad041

By:

Hu, Xiaoming;
Jiao, Fuxin;
Deng, Jiali;
Zhou, Ziheng;
Chen, Shanghai;
Liu, Changqin;
Liu, Zhanju;
Guo, Feifan

Publication type:

Article

An ATF4-ATG5 signaling in hypothalamic POMC neurons regulates obesity.

Published in:

Autophagy, 2017, v. 13, n. 6, p. 1088, doi. 10.1080/15548627.2017.1307488

By:

Xiao, Yuzhong;
Deng, Yalan;
Yuan, Feixiang;
Xia, Tingting;
Liu, Hao;
Li, Zhigang;
Chen, Shanghai;
Liu, Zhixue;
Ying, Hao;
Liu, Yi;
Zhai, Qiwei;
Guo, Feifan

Publication type:

Article

MAPK1/3 regulate hepatic lipid metabolism via ATG7-dependent autophagy.

Published in:

Autophagy, 2016, v. 12, n. 3, p. 592, doi. 10.1080/15548627.2015.1135282

By:

Xiao, Yuzhong;
Liu, Hao;
Yu, Junjie;
Zhao, Zilong;
Xiao, Fei;
Xia, Tingting;
Wang, Chunxia;
Li, Kai;
Deng, Jiali;
Guo, Yajie;
Chen, Shanghai;
Chen, Yan;
Guo, Feifan

Publication type:

Article

A novel function of B-cell translocation gene 1 (BTG1) in the regulation of hepatic insulin sensitivity in mice via c-Jun.

Published in:

FASEB Journal, 2016, v. 30, n. 1, p. 348, doi. 10.1096/fj.15-278689

By:

Fei Xiao;
Jiali Deng;
Junjie Yu;
Yajie Guo;
Shanghai Chen;
Feifan Guo

Publication type:

Article

SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity.

Published in:

Diabetes, 2018, v. 67, n. 4, p. 569, doi. 10.2337/db17-1069

By:

Yalan Deng;
Yuzhong Xiao;
Feixiang Yuan;
Yaping Liu;
Xiaoxue Jiang;
Jiali Deng;
Fejes-Toth, Geza;
Naray-Fejes-Toth, Aniko;
Shanghai Chen;
Yan Chen;
Hao Ying;
Qiwei Zhai;
Yousheng Shu;
Feifan Guo

Publication type:

Article

Erratum. Deletion of ATF4 in AgRP Neurons Promotes Fat Loss Mainly via Increasing Energy Expenditure. Diabetes 2017;66:640-650.

Published in:

2017

By:

Deng, Jiali;
Yuan, Feixiang;
Guo, Yajie;
Xiao, Yuzhong;
Niu, Yuguo;
Deng, Yalan;
Han, Xiao;
Guan, Youfei;
Chen, Shanghai;
Guo, Feifan

Publication type:

journal article

ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.

Published in:

2017

By:

Yuzhong Xiao;
Yalan Deng;
Feixiang Yuan;
Tingting Xia;
Hao Liu;
Zhigang Li;
Zhixue Liu;
Hao Ying;
Yi Liu;
Qiwei Zhai;
Shanghai Chen;
Feifan Guo;
Xiao, Yuzhong;
Deng, Yalan;
Yuan, Feixiang;
Xia, Tingting;
Liu, Hao;
Li, Zhigang;
Liu, Zhixue;
Ying, Hao

Publication type:

journal article

A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα.

Published in:

2016

By:

Yajie Guo;
Junjie Yu;
Jiali Deng;
Bin Liu;
Yuzhong Xiao;
Kai Li;
Fei Xiao;
Feixiang Yuan;
Yong Liu;
Shanghai Chen;
Feifan Guo;
Guo, Yajie;
Yu, Junjie;
Deng, Jiali;
Liu, Bin;
Xiao, Yuzhong;
Li, Kai;
Xiao, Fei;
Yuan, Feixiang;
Liu, Yong

Publication type:

journal article

Activation of ERK1/2 Ameliorates Liver Steatosis in Leptin Receptor-Deficient (db/db) Mice via Stimulating ATG7-Dependent Autophagy.

Published in:

2016

By:

Yuzhong Xiao;
Hao Liu;
Junjie Yu;
Zilong Zhao;
Fei Xiao;
Tingting Xia;
Chunxia Wang;
Kai Li;
Jiali Deng;
Yajie Guo;
Shanghai Chen;
Yan Chen;
Feifan Guo;
Xiao, Yuzhong;
Liu, Hao;
Yu, Junjie;
Zhao, Zilong;
Xiao, Fei;
Xia, Tingting;
Wang, Chunxia

Publication type:

journal article

Hepatic Phosphoserine Aminotransferase 1 Regulates Insulin Sensitivity in Mice via Tribbles Homolog 3.

Published in:

Diabetes, 2015, v. 64, n. 5, p. 1591, doi. 10.2337/db14-1368

By:

Junjie Yu;
Fei Xiao;
Yajie Guo;
Jiali Deng;
Bin Liu;
Qian Zhang;
Kai Li;
Chunxia Wang;
Shanghai Chen;
Feifan Guo

Publication type:

Article

A Novel Function of MicroRNA 130a-3p in Hepatic Insulin Sensitivity and Liver Steatosis.

Published in:

Diabetes, 2014, v. 63, n. 8, p. 2631, doi. 10.2337/db13-1689

By:

Fei Xiao;
Junjie Yu;
Bin Liu;
Yajie Guo;
Kai Li;
Jiali Deng;
Jin Zhang;
Chunxia Wang;
Shanghai Chen;
Ying Du;
Yingli Lu;
Yuzhong Xiao;
Zhou Zhang;
Feifan Guo

Publication type:

Article

PRLR Regulates Hepatic Insulin Sensitivity in Mice via STAT5.

Published in:

Diabetes, 2013, v. 62, n. 9, p. 3103, doi. 10.2337/db13-0182

By:

Junjie Yu;
Fei Xiao;
Qian Zhang;
Bin Liu;
Yajie Guo;
Ziquan Lv;
Tingting Xia;
Shanghai Chen;
Kai Li;
Ying Du;
Feifan Guo

Publication type:

Article

Central activating transcription factor 4 (ATF4) regulates hepatic insulin resistance in mice via S6K1 signaling and the vagus nerve.

Published in:

2013

By:

Zhang, Qian;
Yu, Junjie;
Liu, Bin;
Lv, Ziquan;
Xia, Tingting;
Xiao, Fei;
Chen, Shanghai;
Guo, Feifan

Publication type:

journal article

Central Activating Transcription Factor 4 (ATF4) Regulates Hepatic Insulin Resistance in Mice via S6K1 Signaling and the Vagus Nerve.

Published in:

Diabetes, 2013, v. 62, n. 7, p. 2230, doi. 10.2337/db12-1050

By:

Qian Zhang;
Junjie Yu;
Bin Liu;
Ziquan Lv;
Tingting Xia;
Fei Xiao;
Shanghai Chen;
Feifan Guo

Publication type:

Article

S6K1 in the central nervous system regulates energy expenditure via MC4R/CRH pathways in response to deprivation of an essential amino acid.

Published in:

2012

By:

Xia T;
Cheng Y;
Zhang Q;
Xiao F;
Liu B;
Chen S;
Guo F;
Xia, Tingting;
Cheng, Ying;
Zhang, Qian;
Xiao, Fei;
Liu, Bin;
Chen, Shanghai;
Guo, Feifan

Publication type:

journal article

S6K1 in the Central Nervous System Regulates Energy Expenditure via MC4R/CRH Pathways in Response to Deprivation of an Essential Amino Acid.

Published in:

Diabetes, 2012, v. 61, n. 10, p. 2461, doi. 10.2337/db11-1278

By:

Tingting Xia;
Ying Cheng;
Qian Zhang;
Fei Xiao;
Bin Liu;
Shanghai Chen;
Feifan Guo

Publication type:

Article

Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways.

Published in:

Diabetes, 2011, v. 60, n. 3, p. 746, doi. 10.2337/db10-1246

By:

Fei Xiao;
Zhiying Huang;
Houkai Li;
Junjie Yu;
Chunxia Wang;
Shanghai Chen;
Qingshu Meng;
Ying Cheng;
Xiang Gao;
Jia Li;
Yong Liu;
Feifan Guo

Publication type:

Article

Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue.

Published in:

Diabetes, 2010, v. 59, n. 1, p. 17, doi. 10.2337/db09-0929

By:

Ying Cheng;
Qingshu Meng;
Chunxia Wang;
Houkai Li;
Zhiying Huang;
Shanghai Chen;
Fei Xiao;
Feifan Guo

Publication type:

Article

Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve.

Published in:

Diabetologia, 2014, v. 57, n. 10, p. 2136, doi. 10.1007/s00125-014-3336-3

By:

Xiao, Fei;
Xia, Tingting;
Lv, Ziquan;
Zhang, Qian;
Xiao, Yuzhong;
Yu, Junjie;
Liu, Hao;
Deng, Jiali;
Guo, Yajie;
Wang, Chunxia;
Li, Kai;
Liu, Bin;
Chen, Shanghai;
Guo, Feifan

Publication type:

Article

Hepatic serum- and glucocorticoid-regulated protein kinase 1 (SGK1) regulates insulin sensitivity in mice via extracellular-signal-regulated kinase 1/2 (ERK1/2).

Published in:

Biochemical Journal, 2014, v. 464, n. 2, p. 281, doi. 10.1042/BJ20141005

By:

Hao Liu;
Junjie Yu;
Tingting Xia;
Yuzhong Xiao;
Qian Zhang;
Bin Liu;
Yajie Guo;
Jiali Deng;
Yalan Deng;
Shanghai Chen;
Naray-Fejes-Toth, Aniko;
Fejes-Toth, Geza;
Feifan Guo

Publication type:

Article

Blautia Coccoides is a Newly Identified Bacterium Increased by Leucine Deprivation and has a Novel Function in Improving Metabolic Disorders.

Published in:

Advanced Science, 2024, v. 11, n. 18, p. 1, doi. 10.1002/advs.202309255

By:

Niu, Yuguo;
Hu, Xiaoming;
Song, Yali;
Wang, Cunchuan;
Luo, Peixiang;
Ni, Shihong;
Jiao, Fuxin;
Qiu, Ju;
Jiang, Weihong;
Yang, Sheng;
Chen, Jun;
Huang, Rui;
Jiang, Haizhou;
Chen, Shanghai;
Zhai, Qiwei;
Xiao, Jia;
Guo, Feifan

Publication type:

Article

Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16662-2

By:

Yuan, Feixiang;
Jiang, Haizhou;
Yin, Hanrui;
Jiang, Xiaoxue;
Jiao, Fuxin;
Chen, Shanghai;
Ying, Hao;
Chen, Yan;
Zhai, Qiwei;
Guo, Feifan

Publication type:

Article

ATF4 regulates lipid metabolism and thermogenesis.

Published in:

Cell Research, 2010, v. 20, n. 2, p. 174, doi. 10.1038/cr.2010.4

By:

Chunxia Wang;
Zhiying Huang;
Ying Du;
Ying Cheng;
Shanghai Chen;
Feifan Guo

Publication type:

Article

Inhibition of c-Jun in AgRP neurons increases stress-induced anxiety and colitis susceptibility.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04425-w

By:

Jiao, Fuxin;
Hu, Xiaoming;
Yin, Hanrui;
Yuan, Feixiang;
Zhou, Ziheng;
Wu, Wei;
Chen, Shanghai;
Liu, Zhanju;
Guo, Feifan

Publication type:

Article

BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism.

Published in:

Science Signaling, 2016, v. 9, n. 428, p. 1, doi. 10.1126/scisignal.aad8581

By:

Fei Xiao;
Jiali Deng;
Yajie Guo;
Yuguo Niu;
Feixiang Yuan;
Junjie Yu;
Shanghai Chen;
Feifan Guo

Publication type:

Article

Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.

Published in:

2022

By:

Niu, Yuguo;
Jiang, Haizhou;
Yin, Hanrui;
Wang, Fenfen;
Hu, Ronggui;
Hu, Xiaoming;
Peng, Bo;
Shu, Yousheng;
Li, Zhigang;
Chen, Shanghai;
Guo, Feifan

Publication type:

journal article

Intermittent Leucine Deprivation Produces Long-lasting Improvement in Insulin Sensitivity by Increasing Hepatic Gcn2 Expression.

Published in:

2022

By:

Yin, Hanrui;
Yuan, Feixiang;
Jiao, Fuxin;
Niu, Yuguo;
Jiang, Xiaoxue;
Deng, Jiali;
Guo, Yajie;
Chen, Shanghai;
Zhai, Qiwei;
Hu, Cheng;
Li, Yiming;
Guo, Feifan

Publication type:

journal article

A fifty percent leucine-restricted diet reduces fat mass and improves glucose regulation.

Published in:

Nutrition & Metabolism, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12986-021-00564-1

By:

Zhou, Ziheng;
Yin, Hanrui;
Guo, Yajie;
Fang, Yuanyuan;
Yuan, Feixiang;
Chen, Shanghai;
Guo, Feifan

Publication type:

Article