Works by Shan, Changliang

Results: 39

The non-metabolic function of 6PGD coordinates CCNA2 and HMGA2 expression to drive colorectal cancer progression and drug response.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03450-3

By:

Sun, Mingming;
Yan, Qi;
Zhai, Xinru;
Dai, Xintong;
Yang, Chenxin;
Zhao, Huifang;
Lai, Sizhen;
Wang, Jiyan;
Li, Lian;
Li, Zhen;
Li, Yanping;
Wang, Taoyuan;
He, Tao;
Xue, Jun;
Jia, Zhenghu;
Zhang, Chunze;
Zhang, Shuai;
Shan, Changliang

Publication type:

Article

Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00421

By:

Wujian Zheng;
Qi Feng;
Jiao Liu;
Yanke Guo;
Lvfen Gao;
Ruiman Li;
Meng Xu;
Guizhen Yan;
Zhinan Yin;
Shuai Zhang;
Shuangping Liu;
Changliang Shan

Publication type:

Article

APEX2‐based Proximity Labeling of Atox1 Identifies CRIP2 as a Nuclear Copper‐binding Protein that Regulates Autophagy Activation.

Published in:

Angewandte Chemie, 2021, v. 133, n. 48, p. 25550, doi. 10.1002/ange.202108961

By:

Chen, Lin;
Li, Na;
Zhang, Meiqi;
Sun, Mingming;
Bian, Jiaxuan;
Yang, Bo;
Li, Zhengcunxiao;
Wang, Jiayu;
Li, Fei;
Shi, Xiaomeng;
Wang, Yuan;
Yuan, Feng;
Zou, Peng;
Shan, Changliang;
Wang, Jing

Publication type:

Article

Decreased SLC27A5 Suppresses Lipid Synthesis and Tyrosine Metabolism to Activate the Cell Cycle in Hepatocellular Carcinoma.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 234, doi. 10.3390/biomedicines10020234

By:

Wang, Jiyan;
Qiao, Yaya;
Sun, Huanran;
Chang, Hongkai;
Zhao, Huifang;
Zhang, Shuai;
Shan, Changliang

Publication type:

Article

Metabolomics reveals the effect of valproic acid on MCF-7 and MDA-MB-231 cells.

Published in:

Xenobiotica, 2020, v. 50, n. 3, p. 252, doi. 10.1080/00498254.2019.1618510

By:

Zhou, Xingzhi;
Li, Zhen;
Wang, Xuanyu;
Jiang, Ge;
Shan, Changliang;
Liu, Shuangping

Publication type:

Article

micro RNA-133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the EGFR/ Akt signaling pathway.

Published in:

FEBS Journal, 2013, v. 280, n. 16, p. 3962, doi. 10.1111/febs.12398

By:

Cui, Wenjing;
Zhang, Shuai;
Shan, Changliang;
Zhou, Li;
Zhou, Zhemin

Publication type:

Article

The Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance.

Published in:

Life (2075-1729), 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/life12020271

By:

Song, Jiaqi;
Sun, Huanran;
Zhang, Shuai;
Shan, Changliang

Publication type:

Article

PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11304, doi. 10.3390/ijms231911304

By:

Sun, Mingming;
Yan, Qi;
Qiao, Yaya;
Zhao, Huifang;
Wang, Yingzhi;
Shan, Changliang;
Zhang, Shuai

Publication type:

Article

Identification of HGD and GSTZ1 as Biomarkers Involved Metabolic Reprogramming in Kidney Renal Clear Cell Carcinoma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4583, doi. 10.3390/ijms23094583

By:

Wang, Jiyan;
Chang, Hongkai;
Su, Meng;
Qiao, Yaya;
Sun, Huanran;
Zhao, Yongshan;
Zhang, Shuai;
Shan, Changliang

Publication type:

Article

Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer.

Published in:

Molecular & Cellular Biochemistry, 2021, v. 476, n. 9, p. 3423, doi. 10.1007/s11010-021-04171-9

By:

Li, Zhen;
Su, Jin;
Sun, Mingming;
Song, Jiaqi;
Sun, Huanran;
Fan, Jun;
Chen, Guo;
Shan, Changliang;
Qi, Qi;
Zhang, Shuai

Publication type:

Article

Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.

Published in:

Cell Transplantation, 2021, v. 30, p. 1, doi. 10.1177/09636897211027524

By:

Li, Zhen;
Yang, Lina;
Zhang, Shuai;
Song, Jiaqi;
Sun, Huanran;
Shan, Changliang;
Wang, Dan;
Liu, Shuangping

Publication type:

Article

APEX2‐based Proximity Labeling of Atox1 Identifies CRIP2 as a Nuclear Copper‐binding Protein that Regulates Autophagy Activation.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 48, p. 25346, doi. 10.1002/anie.202108961

By:

Chen, Lin;
Li, Na;
Zhang, Meiqi;
Sun, Mingming;
Bian, Jiaxuan;
Yang, Bo;
Li, Zhengcunxiao;
Wang, Jiayu;
Li, Fei;
Shi, Xiaomeng;
Wang, Yuan;
Yuan, Feng;
Zou, Peng;
Shan, Changliang;
Wang, Jing

Publication type:

Article

miRNA-520b and miR-520e sensitize breast cancer cells to complement attack via directly targeting 3'UTR of CD46.

Published in:

Cancer Biology & Therapy, 2010, v. 10, n. 3, p. 232, doi. 10.4161/cbt.10.3.12277

By:

Wenjing Cui;
Yiwen Zhang;
Nan Hu;
Changliang Shan;
Shuai Zhang;
Weiying Zhang;
Xiaodong Zhang;
Lihong Ye

Publication type:

Article

Targeting CDK4/6 suppresses colorectal cancer by destabilizing YAP1.

Published in:

MedComm, 2025, v. 6, n. 3, p. 1, doi. 10.1002/mco2.70103

By:

Wen, Yalei;
Yang, Xiao;
Li, Shengrong;
Huang, Lei;
Chen, Jiayi;
Tan, Lirong;
Ma, Xiuqing;
Zhu, Yingjie;
Li, Zhengqiu;
Shan, Changliang;
Zhang, Chunze;
Zhang, Qiushi;
Liang, Mingchao;
Zhang, Haoxing;
Liu, Tongzheng

Publication type:

Article

Dimethylaminomicheliolide (DMAMCL) Suppresses the Proliferation of Glioblastoma Cells via Targeting Pyruvate Kinase 2 (PKM2) and Rewiring Aerobic Glycolysis.

Published in:

Frontiers in Oncology, 2019, p. 1, doi. 10.3389/fonc.2019.00993

By:

Guo, Jianshuang;
Xue, Qingqing;
Liu, Kaihui;
Ge, Weizhi;
Liu, Wenjie;
Wang, Jiyan;
Zhang, Mengyi;
Li, Qiu-ying;
Cai, Dongpo;
Shan, Changliang;
Zhang, Chunze;
Liu, Xinqi;
Li, Jing

Publication type:

Article

SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03053-4

By:

Xu, Tong;
Li, Xichuan;
Zhao, Wennan;
Wang, Xue;
Jin, Leixin;
Feng, Zhiqiang;
Li, Huixiang;
Zhang, Mingzhe;
Tian, Yiqing;
Hu, Ge;
Yue, Yuan;
Dai, Xintong;
Shan, Changliang;
Zhang, Weihua;
Zhang, Chunze;
Zhang, Youcai

Publication type:

Article

Hepatitis B virus X protein protects hepatoma and hepatic cells from complement-dependent cytotoxicity by up-regulation of CD46

Published in:

FEBS Letters, 2013, v. 587, n. 6, p. 645, doi. 10.1016/j.febslet.2013.01.019

By:

Zhang, Shuai;
Shan, Changliang;
Cui, Wenjing;
You, Xiaona;
Du, Yumei;
Kong, Guangyao;
Gao, Fabao;
Ye, Lihong;
Zhang, Xiaodong

Publication type:

Article

Involvement of hepatitis B virus X gene (HBx) integration in hepatocarcinogenesis via a recombination of HBx/Alu core sequence/subtelomeric DNA

Published in:

FEBS Letters, 2012, v. 586, n. 19, p. 3215, doi. 10.1016/j.febslet.2012.06.039

By:

Zhang, Xuan;
You, Xiaona;
Li, Nan;
Zhang, Weiying;
Gagos, Sarantis;
Wang, Qi;
Banos, Aggelos;
Cai, Na;
Zhang, Huakun;
Zhang, Hang;
Zhang, Xuezhi;
Shan, Changliang;
Qiu, Liyan;
Zhang, Shuai;
Lv, Na;
Chen, Minshan;
Du, Yumei;
Xia, Jianchuan;
Ye, Lihong;
Zhang, Xiaodong

Publication type:

Article

HBXIP upregulates CD46, CD55 and CD59 through ERK1/2/NF-κB signaling to protect breast cancer cells from complement attack

Published in:

FEBS Letters, 2012, v. 586, n. 6, p. 766, doi. 10.1016/j.febslet.2012.01.039

By:

Cui, Wenjing;
Zhao, Yu;
Shan, Changliang;
Kong, Guangyao;
Hu, Nan;
Zhang, Yiwen;
Zhang, Shuai;
Zhang, Weiying;
Zhang, Yingyi;
Zhang, Xiaodong;
Ye, Lihong

Publication type:

Article

Identification of TAT as a Biomarker Involved in Cell Cycle and DNA Repair in Breast Cancer.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 9, p. 1088, doi. 10.3390/biom14091088

By:

Xie, Fei;
Hua, Saiwei;
Guo, Yajuan;
Wang, Taoyuan;
Shan, Changliang;
Zhang, Lianwen;
He, Tao

Publication type:

Article

Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma.

Published in:

Theranostics, 2025, v. 15, n. 4, p. 1285, doi. 10.7150/thno.102228

By:

Xiao Hu;
Xiaomei Tang;
Xiaoman Tian;
Xing Lv;
Yuanyuan Zhang;
Yingyue Pang;
Weilong Deng;
Yali Wang;
Changliang Shan;
Luqing Shang

Publication type:

Article

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.

Published in:

Nature Communications, 2013, v. 4, n. 4, p. 1790, doi. 10.1038/ncomms2759

By:

Hitosugi, Taro;
Zhou, Lu;
Fan, Jun;
Elf, Shannon;
Zhang, Liang;
Xie, Jianxin;
Wang, Yi;
Gu, Ting-Lei;
Ale?kovi?, Masa;
LeRoy, Gary;
Kang, Yibin;
Kang, Hee-Bum;
Seo, Jae-Ho;
Shan, Changliang;
Jin, Peng;
Gong, Weimin;
Lonial, Sagar;
Arellano, Martha L.;
Khoury, Hanna J.;
Chen, Georgia Z.

Publication type:

Article

The Potential Mechanisms of Cinobufotalin Treating Colon Adenocarcinoma by Network Pharmacology.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.934729

By:

Wang, Jiyan;
Chang, Hongkai;
Su, Meng;
Zhao, Huifang;
Qiao, Yaya;
Wang, Yu;
Shang, Luqing;
Shan, Changliang;
Zhang, Shuai

Publication type:

Article

PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer.

Published in:

Cancers, 2022, v. 14, n. 14, p. N.PAG, doi. 10.3390/cancers14143370

By:

Wang, Taoyuan;
Tang, Tiansheng;
Jiang, Youguo;
He, Tao;
Qi, Luyu;
Chang, Hongkai;
Qiao, Yaya;
Sun, Mingming;
Shan, Changliang;
Zhu, Xinyuan;
Liu, Jianshi;
Wang, Jiyan

Publication type:

Article

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.

Published in:

Nature Chemistry, 2015, v. 7, n. 12, p. 968, doi. 10.1038/nchem.2381

By:

Wang, Jing;
Luo, Cheng;
Shan, Changliang;
You, Qiancheng;
Lu, Junyan;
Elf, Shannon;
Zhou, Yu;
Wen, Yi;
Vinkenborg, Jan L.;
Fan, Jun;
Kang, Heebum;
Lin, Ruiting;
Han, Dali;
Xie, Yuxin;
Karpus, Jason;
Chen, Shijie;
Ouyang, Shisheng;
Luan, Chihao;
Zhang, Naixia;
Ding, Hong

Publication type:

Article

FTO promotes colorectal cancer progression and chemotherapy resistance via demethylating G6PD/PARP1.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 3, p. 1, doi. 10.1002/ctm2.772

By:

Wang, Jiyan;
Qiao, Yaya;
Sun, Mingming;
Sun, Huanran;
Xie, Fei;
Chang, Hongkai;
Wang, Yingzhi;
Song, Jiaqi;
Lai, Sizhen;
Yang, Chenxin;
Li, Xichuan;
Liu, Shuangping;
Zhao, Xuanzhu;
Ni, Kemin;
Meng, Kewei;
Zhang, Shuai;
Shan, Changliang;
Zhang, Chunze

Publication type:

Article

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.

Published in:

Nature Cell Biology, 2015, v. 17, n. 11, p. 1484, doi. 10.1038/ncb3255

By:

Lin, Ruiting;
Elf, Shannon;
Shan, Changliang;
Kang, Hee-Bum;
Ji, Quanjiang;
Zhou, Lu;
Hitosugi, Taro;
Zhang, Liang;
Zhang, Shuai;
Seo, Jae Ho;
Xie, Jianxin;
Tucker, Meghan;
Gu, Ting-Lei;
Sudderth, Jessica;
Jiang, Lei;
Mitsche, Matthew;
DeBerardinis, Ralph J.;
Wu, Shaoxiong;
Li, Yuancheng;
Mao, Hui

Publication type:

Article

Hepatitis B Virus X Protein Drives Multiple Cross-Talk Cascade Loops Involving NF-κB, 5-LOX, OPN and Capn4 to Promote Cell Migration.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031458

By:

Xuan Zhang;
Xiaona You;
Qi Wang;
Tao Zhang;
Yumei Du;
Na Lv;
Zhao Zhang;
Shuai Zhang;
Changliang Shan;
Lihong Ye;
Xiaodong Zhang

Publication type:

Article

Upregulated MicroRNA-29a by Hepatitis B Virus X Protein Enhances Hepatoma Cell Migration by Targeting PTEN in Cell Culture Model.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019518

By:

Guangyao Kong;
Junping Zhang;
Shuai Zhang;
Changliang Shan;
Lihong Ye;
Xiaodong Zhang

Publication type:

Article

Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2.

Published in:

Cell Research, 2010, v. 20, n. 5, p. 563, doi. 10.1038/cr.2010.49

By:

Changliang Shan;
Fuqing Xu;
Shuai Zhang;
Jiacong You;
Xiaona You;
Liyan Qiu;
Jie Zheng;
Lihong Ye;
Xiaodong Zhang

Publication type:

Article

Copper Chaperone for Superoxide Dismutase Promotes Breast Cancer Cell Proliferation and Migration via ROS-Mediated MAPK/ERK Signaling.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00356

By:

Li, Yanping;
Liang, Ronghui;
Zhang, Xiaoya;
Wang, Jiyan;
Shan, Changliang;
Liu, Shuangping;
Li, Leilei;
Zhang, Shuai

Publication type:

Article

Hepatitis B virus X protein activates CD59 involving DNA binding and let-7i in protection of hepatoma and hepatic cells from complement attack.

Published in:

Carcinogenesis, 2011, v. 32, n. 8, p. 1190, doi. 10.1093/carcin/bgr106

By:

Shan, Changliang;
Zhang, Shuai;
Cui, Wenjing;
You, Xiaona;
Kong, Guangyao;
Du, Yumei;
Qiu, Liyan;
Ye, Lihong;
Zhang, Xiaodong

Publication type:

Article

Glucose-6-phosphate dehydrogenase: a therapeutic target for ovarian cancer.

Published in:

Expert Opinion on Therapeutic Targets, 2023, v. 27, n. 8, p. 733, doi. 10.1080/14728222.2023.2247558

By:

Wang, Chenxi;
Yu, Chenxi;
Chang, Hongkai;
Song, Jiaqi;
Zhang, Shuai;
Zhao, Jianguo;
Wang, Jiyan;
Wang, Tao;
Qi, Qi;
Shan, Changliang

Publication type:

Article

Correction to: Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation.

Published in:

2025

By:

Zhang, Shuai;
Sheng, Hao;
Zhang, Xiaoya;
Qi, Qi;
Chan, Chi Bun;
Li, Leilei;
Shan, Changliang;
Ye, Keqiang

Publication type:

Correction Notice

Correction: 4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.

Published in:

2025

By:

Shan, Changliang;
Lu, Zhaoliang;
Li, Zhen;
Sheng, Hao;
Fan, Jun;
Qi, Qi;
Liu, Shuangping;
Zhang, Shuai

Publication type:

Correction Notice

Correction: Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer.

Published in:

2020

By:

Qi, Jianjun;
Zhou, Ningning;
Li, Liyi;
Mo, Shouyong;
Zhou, Yidan;
Deng, Yao;
Chen, Ting;
Shan, Changliang;
Chen, Qin;
Lu, Bin

Publication type:

Correction Notice

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer.

Published in:

Cell Death & Disease, 2020, v. 11, n. 7, p. 1, doi. 10.1038/s41419-020-02779-1

By:

Qi, Jianjun;
Zhou, Ningning;
Li, Liyi;
Mo, Shouyong;
Zhou, Yidan;
Deng, Yao;
Chen, Ting;
Shan, Changliang;
Chen, Qin;
Lu, Bin

Publication type:

Article

4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.

Published in:

Cell Death & Disease, 2019, v. 10, n. 7, p. N.PAG, doi. 10.1038/s41419-019-1756-1

By:

Shan, Changliang;
Lu, Zhaoliang;
Li, Zhen;
Sheng, Hao;
Fan, Jun;
Qi, Qi;
Liu, Shuangping;
Zhang, Shuai

Publication type:

Article

Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation.

Published in:

Cell Death & Disease, 2019, v. 10, n. 3, p. 1, doi. 10.1038/s41419-019-1452-1

By:

Zhang, Shuai;
Sheng, Hao;
Zhang, Xiaoya;
Qi, Qi;
Chan, Chi Bun;
Li, Leilei;
Shan, Changliang;
Ye, Keqiang

Publication type:

Article