Works by Sham, Pak

Results: 326

Genetically deprived vitamin D exposure predisposes to atrial fibrillation.

Published in:

2017

By:

Yap-Hang Chan;
Kai-Hang Yiu;
Jo Jo Hai;
Pak-Hei Chan;
Tai-Hing Lam;
Ben J. Cowling;
Pak-Chung Sham;
Chu-Pak Lau;
Karen Siu-Ling Lam;
Chung-Wah Siu;
Hung-Fat Tse;
Chan, Yap-Hang;
Yiu, Kai-Hang;
Hai, Jo Jo;
Chan, Pak-Hei;
Lam, Tai-Hing;
Cowling, Ben J;
Sham, Pak-Chung;
Lau, Chu-Pak;
Lam, Karen Siu-Ling

Publication type:

journal article

The Effect of Paternal Age on Relapse in First-Episode Schizophrenia.

Published in:

2015

By:

Hui, Christy L. M.;
Chiu, Cindy P. Y.;
Yuet-Keung Li;
Chi-Wing Law;
Wing-Chung Chang;
Chan, Sherry K. W.;
Lee, Edwin H. M.;
Pak Sham;
Chen, Eric Y. H.;
Li, Yuet-Keung;
Law, Chi-Wing;
Chang, Wing-Chung;
Sham, Pak

Publication type:

journal article

The relationship of fatigue to mental and physical health in a community sample.

Published in:

2005

By:

Williamson, Richard J.;
Purcell, Shaun;
Sterne, Abram;
Wessely, Simon;
Hotopf, Matthew;
Farmer, Anne;
Sham, Pak;
Sham, Pak C

Publication type:

journal article

Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD.

Published in:

Journal of Neurodevelopmental Disorders, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s11689-025-09626-4

By:

Zhong, Yuanxin;
Baum, Larry W.;
Tubbs, Justin D.;
Ye, Rui;
Chen, Lu Hua;
Wu, Tian;
Hung, Se-Fong;
Tang, Chun-Pan;
Ho, Ting-Pong;
Moyzis, Robert;
Swanson, James;
Lee, Chi-Chiu;
Sham, Pak C.;
Leung, Patrick W. L.

Publication type:

Article

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality.

Published in:

2007

By:

Fogh, Isabella;
Rijsdijk, Fruhling;
Andersen, Peter;
Sham, Pak;
Knight, Joanne;
Neale, Benjamin;
McKenna-Yasek, Diane;
Silani, Vincenzo;
Brown, Robert;
Powell, John;
Al-Chalabi, Ammar

Publication type:

Letter

Clarifying the causes of consistent and inconsistent findings in genetics.

Published in:

Genetic Epidemiology, 2022, v. 46, n. 7, p. 372, doi. 10.1002/gepi.22459

By:

Dattani, Saloni;
Howard, David M.;
Lewis, Cathryn M.;
Sham, Pak C.

Publication type:

Article

Intermediate confounding in trio relationships: The importance of complete data in effect size estimation.

Published in:

Genetic Epidemiology, 2020, v. 44, n. 4, p. 395, doi. 10.1002/gepi.22294

By:

Tubbs, Justin D.;
Zhang, Yan D.;
Sham, Pak C.

Publication type:

Article

Multifactorial disease risk calculator: Risk prediction for multifactorial disease pedigrees.

Published in:

Genetic Epidemiology, 2018, v. 42, n. 2, p. 130, doi. 10.1002/gepi.22101

By:

Campbell, Desmond D.;
Yiming Li;
Sham, Pak C.

Publication type:

Article

Polygenic scores via penalized regression on summary statistics.

Published in:

Genetic Epidemiology, 2017, v. 41, n. 6, p. 469, doi. 10.1002/gepi.22050

By:

Mak, Timothy Shin Heng;
Porsch, Robert Milan;
Choi, Shing Wan;
Zhou, Xueya;
Sham, Pak Chung

Publication type:

Article

SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests.

Published in:

Genetic Epidemiology, 2015, v. 39, n. 5, p. 395, doi. 10.1002/gepi.21898

By:

Li, Jiang;
Sham, Pak Chung;
Song, Youqiang;
Li, Miaoxin

Publication type:

Article

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study.

Published in:

Genetic Epidemiology, 2011, v. 35, n. 6, p. 447, doi. 10.1002/gepi.20593

By:

So, Hon-Cheong;
Li, Miaoxin;
Sham, Pak C.

Publication type:

Article

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases.

Published in:

Genetic Epidemiology, 2011, v. 35, n. 5, p. 310, doi. 10.1002/gepi.20579

By:

So, Hon-Cheong;
Gui, Allen H.S.;
Cherny, Stacey S.;
Sham, Pak C.

Publication type:

Article

Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates.

Published in:

Genetic Epidemiology, 2010, v. 34, n. 2, p. 159, doi. 10.1002/gepi.20446

By:

Campbell, Desmond D.;
Sham, Pak C.;
Knight, Jo;
Wickham, Harvey;
Landau, Sabine

Publication type:

Article

CLUMPHAP: a simple tool for performing haplotype-based association analysis.

Published in:

Genetic Epidemiology, 2008, v. 32, n. 6, p. 539, doi. 10.1002/gepi.20327

By:

Knight, Jo;
Curtis, David;
Sham, Pak C.

Publication type:

Article

Population differences in the International Multi-Centre ADHD Gene Project.

Published in:

Genetic Epidemiology, 2008, v. 32, n. 2, p. 98, doi. 10.1002/gepi.20265

By:

Neale, Benjamin M.;
Sham, Pak C.;
Purcell, Shaun;
Banaschewski, Tobias;
Buitelaar, Jan;
Franke, Barbara;
Sonuga-Barke, Edmund;
Ebstein, Richard;
Eisenberg, Jacques;
Mulligan, Aisling;
Gill, Michael;
Manor, Iris;
Miranda, Ana;
Mulas, Fernando;
Oades, Robert D.;
Roeyers, Herbert;
Rothenberger, Aribert;
Sergeant, Joseph;
Steinhausen, Hans-Christoph;
Taylor, Eric

Publication type:

Article

Erratum.

Published in:

Genetic Epidemiology, 2008, v. 32, n. 2, p. 186, doi. 10.1002/gepi.20293

By:

Neale, Benjamin M.;
Sham, Pak C.;
Purcell, Shaun;
Banaschewski, Tobias;
Buitelaar, Jan;
Franke, Barbara;
Sonuga-Barke, Edmund;
Ebstein, Richard;
Eisenberg, Jacques;
Mulligan, Aisling;
Gill, Michael;
Manor, Iris;
Miranda, Ana;
Mulas, Fernando;
Oades, Robert D.;
Roeyers, Herbert;
Rothenberger, Aribert;
Sergeant, Joseph;
Steinhausen, Hans-Christoph;
Taylor, Eric

Publication type:

Article

The Effect of Genotype and Pedigree Error on Linkage Analysis: Analysis of Three Asthma Genome Scans.

Published in:

Genetic Epidemiology, 2001, v. 21, p. S117, doi. 10.1002/gepi.2001.21.s1.s117

By:

Cherny, Stacey S.;
Abecasis, Gonçalo R.;
Cookson, William O.C.;
Sham, Pak C.;
Cardon, Lon R.

Publication type:

Article

Association Analysis in a Variance Components Framework.

Published in:

Genetic Epidemiology, 2001, v. 21, p. S341, doi. 10.1002/gepi.2001.21.s1.s341

By:

Abecasis, Gonçalo R.;
Cardon, Lon R.;
Cookson, William O.C.;
Sham, Pak C.;
Cherny, Stacey S.

Publication type:

Article

Variance-components QTL linkage analysis of selected and non-normal samples: Conditioning on trait values.

Published in:

Genetic Epidemiology, 2000, v. 19, n. S1, p. S22, doi. 10.1002/1098-2272(2000)19:1+<::AID-GEPI4>3.0.CO;2-S

By:

Sham, Pak Chung;
Zhao, Jing Hua;
Cherny, Stacey S.;
Hewitt, John K.

Publication type:

Article

Comparison of GENEHUNTER and MFLINK for analysis of COGA linkage data.

Published in:

Genetic Epidemiology, 1999, v. 17, p. S115, doi. 10.1002/gepi.1370170720

By:

Curtis, David;
Zhao, Jing Hua;
Sham, Pak C.

Publication type:

Article

Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis.

Published in:

Human Mutation, 2017, v. 38, n. 11, p. 1500, doi. 10.1002/humu.23296

By:

Gao, Wenjie;
Chen, Chong;
Zhou, Taifeng;
Yang, Shulan;
Gao, Bo;
Zhou, Hang;
Lian, Chengjie;
Wu, Zizhao;
Qiu, Xianjian;
Yang, Xiaoming;
Alattar, Esam;
Liu, Wentao;
Su, Deying;
Sun, Silong;
Chen, Yulan;
Cheung, Kenneth M. C.;
Song, Youqiang;
Luk, Keith K. D.;
Chan, Danny;
Sham, Pak Chung

Publication type:

Article

wKGGSeq: A Comprehensive Strategy-Based and Disease-Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders.

Published in:

Human Mutation, 2015, v. 36, n. 5, p. 496, doi. 10.1002/humu.22766

By:

Li, Mulin Jun;
Deng, Jiaen;
Wang, Panwen;
Yang, Wanling;
Ho, Shu Leong;
Sham, Pak Chung;
Wang, Junwen;
Li, Miaoxin

Publication type:

Article

Homozygosity mapping on a single patient-identification of homozygous regions of recent common ancestry by using population data.

Published in:

Human Mutation, 2011, v. 32, n. 3, p. 345, doi. 10.1002/humu.21432

By:

Lu Zhang;
Wanling Yang;
Dingge Ying;
Cherny, Stacey S.;
Hildebrandt, Friedhelm;
Pak Chung Sham;
Yu Lung Lau

Publication type:

Article

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.

Published in:

Bioinformatics, 2017, v. 33, n. 6, p. 886, doi. 10.1093/bioinformatics/btw745

By:

Hon-Cheong So;
Sham, Pak C.

Publication type:

Article

Inheritance-mode specific pathogenicity prioritization (ISPP) for human protein coding genes.

Published in:

Bioinformatics, 2016, v. 32, n. 20, p. 3065, doi. 10.1093/bioinformatics/btw381

By:

Hsu, Jacob Shujui;
Kwan, Johnny S. H.;
Zhicheng Pan;
Garcia-Barcelo, Maria-Mercè;
Pak Chung Sham;
Miaoxin Li

Publication type:

Article

Predicting regulatory variants with composite statistic.

Published in:

Bioinformatics, 2016, v. 32, n. 18, p. 2729, doi. 10.1093/bioinformatics/btw288

By:

Jiexing Wu;
Mulin Jun Li;
Liu, Jun S.;
Panwen Wang;
Feng Xu;
Zhicheng Pan;
Pak Chung Sham;
Miaoxin Li;
Zipeng Liu;
Yun Zhu;
Junwen Wang;
Zhengyuan Xia;
Kocher, Jean-Pierre A.

Publication type:

Article

MGAS: a powerful tool for multivariate gene-based genome-wide association analysis.

Published in:

Bioinformatics, 2015, v. 31, n. 7, p. 1007, doi. 10.1093/bioinformatics/btu783

By:

Van der Sluis, Sophie;
Dolan, Conor V.;
Li, Jiang;
Song, Youqiang;
Sham, Pak;
Posthuma, Danielle;
Li, Miao-Xin

Publication type:

Article

Correlated evolution of transcription factors and their binding sites.

Published in:

Bioinformatics, 2011, v. 27, n. 21, p. 2972, doi. 10.1093/bioinformatics/btr503

By:

Yang, Shu;
Yalamanchili, Hari Krishna;
Li, Xinran;
Yao, Kwok-Ming;
Sham, Pak Chung;
Zhang, Michael Q.;
Wang, Junwen

Publication type:

Article

FastPval: a fast and memory efficient program to calculate very low P-values from empirical distribution.

Published in:

Bioinformatics, 2010, v. 26, n. 22, p. 2897, doi. 10.1093/bioinformatics/btq540

By:

Mulin Jun Li;
Pak Chung Sham;
Junwen Wang

Publication type:

Article

IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis.

Published in:

Bioinformatics, 2009, v. 25, n. 11, p. 1449, doi. 10.1093/bioinformatics/btp183

By:

Miao-Xin Li;
Lin Jiang;
Patrick Yu-Ping Kao;
Pak-C. Sham;
You-Qiang Song

Publication type:

Article

WHAP: haplotype-based association analysis.

Published in:

Bioinformatics, 2007, v. 23, n. 2, p. 255, doi. 10.1093/bioinformatics/btl580

By:

Shaun Purcell;
Mark J. Daly;
Pak C. Sham

Publication type:

Article

Statistical power and significance testing in large-scale genetic studies.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 5, p. 335, doi. 10.1038/nrg3706

By:

Sham, Pak C.;
Purcell, Shaun M.

Publication type:

Article

Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization.

Published in:

Advanced Science, 2025, v. 12, n. 2, p. 1, doi. 10.1002/advs.202407628

By:

Ni, Tong;
Sun, Yu;
Li, Zefeng;
Tan, Tao;
Han, Wei;
Li, Miao;
Zhu, Li;
Xiao, Jing;
Wang, Huiying;
Zhang, Wenpei;
Ma, Yitian;
Wang, Biao;
Wen, Di;
Chen, Teng;
Tubbs, Justin;
Zeng, Xiaofeng;
Yan, Jiangwei;
Gui, Hongsheng;
Sham, Pak;
Guan, Fanglin

Publication type:

Article

Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 195, doi. 10.2147/OTT.S71242

By:

Lam, David C. L.;
Luo, Susan Y.;
Wen Deng;
Kwan, Johnny S. H.;
Rodriguez-Canales, Jaime;
Cheung, Annie L. M.;
Cheng, Grace H. W.;
Chi-Ho Lin;
Wistuba, Ignacio I.;
Sham, Pak C.;
Wan, Thomas S. K.;
Sai-Wah Tsao

Publication type:

Article

The genetic and environmental influences of event-related gamma oscillations on bipolar disorder.

Published in:

Bipolar Disorders, 2011, v. 13, n. 3, p. 260, doi. 10.1111/j.1399-5618.2011.00925.x

By:

Hall, Mei‐Hua;
Spencer, Kevin M;
Schulze, Katja;
McDonald, Colm;
Kalidindi, Sridevi;
Kravariti, Eugenia;
Kane, Fergus;
Murray, Robin M;
Bramon, Elvira;
Sham, Pak;
Rijsdijk, Frühling

Publication type:

Article

Are the structural brain deviations associated with bipolar disorder related to susceptibility genes?

Published in:

Bipolar Disorders, 2002, v. 4, p. 35, doi. 10.1034/j.1399-5618.4.s1.9.x

By:

McDonald, Colm;
Marshall, Nicky;
Sham, Pak;
Murray, Robin M

Publication type:

Article

Predicting the number and sizes of IBD regions among family members and evaluating the family size requirement for linkage studies.

Published in:

European Journal of Human Genetics, 2008, v. 16, n. 12, p. 1535, doi. 10.1038/ejhg.2008.116

By:

Wanling Yang;
Zhanyong Wang;
Lusheng Wang;
Pak-Chung Sham;
Peng Huang;
Yu Lung Lau

Publication type:

Article

Mapping of a Hirschsprung's disease locus in 3p21.

Published in:

European Journal of Human Genetics, 2008, v. 16, n. 7, p. 833, doi. 10.1038/ejhg.2008.18

By:

Garcia-Barceló, Maria-Mercè;
Pui-yee Fong;
Tang, Clara S.;
Xiao-ping Miao;
Man-ting So;
Zhen-wei Yuan;
Li, Long;
Wei-hong Guo;
Lei Liu;
Bin Wang;
Xiao-bing Sun;
Liu-ming Huang;
Jin-fa Tou;
Kak-yuen Wong, Kenneth;
Elly Sau-wai Ngan;
Vincent Chi-hang Lui;
Cherny, Stacey S.;
Pak-chung Sham;
Paul Kwong-hang Tam

Publication type:

Article

Is haplotype tagging the panacea to association mapping studies?

Published in:

European Journal of Human Genetics, 2004, v. 12, n. 4, p. 259, doi. 10.1038/sj.ejhg.5201146

By:

Jawaid, Ansar;
Sham, Pak C.;
Makoff, Andrew J.;
Asherson, Philip J.

Publication type:

Article

Family-based association tests for quantitative traits using pooled DNA.

Published in:

European Journal of Human Genetics, 2002, v. 10, n. 12, p. 870, doi. 10.1038/sj.ejhg.5200893

By:

Bader, Joel S;
Sham, Pak

Publication type:

Article

Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy.

Published in:

European Journal of Human Genetics, 2002, v. 10, n. 12, p. 857, doi. 10.1038/sj.ejhg.5200896

By:

Chioza, Barry;
Osei-Lah, Abena;
Nashef, Lina;
Suarez-Merino, Blanca;
Wilkie, Hazel;
Sham, Pak;
Knight, Jo;
Asherson, Philip;
Makoff, Andrew J

Publication type:

Article

Optimal selection strategies for QTL mapping using pooled DNA samples.

Published in:

European Journal of Human Genetics, 2002, v. 10, n. 2, p. 125, doi. 10.1038/sj.ejhg.5200771

By:

Jawaid, Ansar;
Bader, Joel S.;
Purcell, Shaun;
Cherny, Stacey S.;
Sham, Pak

Publication type:

Article

Analytic power calculation for QTL linkage analysis of small pedigrees.

Published in:

European Journal of Human Genetics, 2001, v. 9, n. 5, p. 335, doi. 10.1038/sj.ejhg.5200634

By:

Rijsdijk, Frühling V;
Hewitt, John K;
Sham, Pak C

Publication type:

Article

Patient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis.

Published in:

BMC Medical Genomics, 2017, v. 10, p. 1, doi. 10.1186/s12920-017-0259-0

By:

Guo Cheng;
Ho-Yu Chung, Patrick;
Kin-Wai Chan, Edwin;
Man-Ting So;
Pak-Chung Sham;
Cherny, Stacey S.;
Kwong-Hang Tam, Paul;
Garcia-Barceló, Maria-Mercè

Publication type:

Article

Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes.

Published in:

BMC Medical Genomics, 2016, v. 9, p. 1, doi. 10.1186/s12920-016-0236-z

By:

Wong, John K. L.;
Campbell, Desmond;
Ngo, Ngoc Diem;
Fanny Yeung;
Guo Cheng;
Tang, Clara S. M.;
Chung, Patrick H. Y.;
Ngoc Son Tran;
Man-ting So;
Cherny, Stacey S.;
Sham, Pak C.;
Tam, Paul K.;
Garcia-Barcelo, Maria-Mercè

Publication type:

Article

The common genetic liability between schizophrenia and bipolar disorder: a review.

Published in:

2001

By:

Bramon, Elvira;
Sham, Pak;
Bramon, E;
Sham, P C

Publication type:

journal article

The support of human genetic evidence for approved drug indications.

Published in:

Nature Genetics, 2015, v. 47, n. 8, p. 856, doi. 10.1038/ng.3314

By:

Nelson, Matthew R;
Painter, Jeffery L;
Shen, Judong;
Tipney, Hannah;
Whittaker, John C;
Sanseau, Philippe;
Nicoletti, Paola;
Shen, Yufeng;
Floratos, Aris;
Sham, Pak Chung;
Li, Mulin Jun;
Wang, Junwen;
Cardon, Lon R

Publication type:

Article

Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3.

Published in:

Nature Genetics, 2012, v. 44, n. 9, p. 1026, doi. 10.1038/ng.2367

By:

Cheung, Ching-Lung;
Lau, Kam-Shing;
Ho, Andrew Y Y;
Lee, Ka-Kui;
Tiu, Sau-Cheung;
Lau, Emmy Y F;
Leung, Jenny;
Tsang, Man-Wo;
Chan, Kin-Wah;
Yeung, Chun-Yip;
Woo, Yu-Cho;
Cheung, Elaine Y N;
Hung, Victor H F;
Pang, Ho-Kwong;
Hung, Chi-Sang;
Sham, Pak-Chung;
Kung, Annie W C

Publication type:

Article

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.

Published in:

Nature Genetics, 2010, v. 42, n. 10, p. 902, doi. 10.1038/ng.664

By:

Hysi, Pirro G.;
Young, Terri L.;
Mackey, David A.;
Andrew, Toby;
Fernández-Medarde, Alberto;
Solouki, Abbas M.;
Hewitt, Alex W.;
Macgregor, Stuart;
Vingerling, Johannes R.;
Yi-Ju Li;
Ikram, M. Kamran;
Lee Yiu Fai;
Sham, Pak C.;
Manyes, Lara;
Porteros, Angel;
Lopes, Margarida C.;
Carbonaro, Francis;
Fahy, Samantha J.;
Martin, Nicholas G.;
van Duijn, Cornelia M.

Publication type:

Article

Identification of LTBP2 on Chromosome 14q as a Novel Candidate Gene for Bone Mineral Density Variation and Fracture Risk Association.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 11, p. 4448, doi. 10.1210/jc.2007-2836

By:

Ching-Lung Cheung;
Sham, Pak C.;
Chan, Vivian;
Paterson, Andrew D.;
Luk, Keith D. K.;
Kung, Annie W. C.

Publication type:

Article