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Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men.
- Published in:
- Clinical Drug Investigation, 2015, v. 35, n. 6, p. 353, doi. 10.1007/s40261-015-0285-7
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- Article
An Open-Label Drug–Drug Interaction Study of the Steady-State Pharmacokinetics of Topiramate and Glyburide in Patients with Type 2 Diabetes Mellitus.
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- Clinical Drug Investigation, 2013, v. 33, n. 12, p. 929, doi. 10.1007/s40261-013-0143-4
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- Article
A Phase 1 First‐in‐Human Pharmacokinetic and Pharmacodynamic Study of JNJ‐64264681, a Covalent Inhibitor of Bruton's Tyrosine Kinase.
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- Clinical Pharmacology in Drug Development, 2023, v. 12, n. 6, p. 611, doi. 10.1002/cpdd.1253
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- Article
Pharmacokinetics and Safety of Mavatrep (JNJ‐39439335), a TRPV1 Antagonist in Healthy Japanese and Caucasian Men: A Double‐Blind, Randomized, Placebo‐Controlled, Sequential‐Group Phase 1 Study.
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- Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 712, doi. 10.1002/cpdd.413
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- Article
Bioavailability and Pharmacokinetics of TRPV1 Antagonist Mavatrep (JNJ‐39439335) Tablet and Capsule Formulations in Healthy Men: Two Open‐Label, Crossover, Single‐Dose Phase 1 Studies.
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- Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 699, doi. 10.1002/cpdd.412
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- Article
Pharmacokinetic interactions between topiramate and diltiazem, hydrochlorothiazide, or propranolol.
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- Clinical Pharmacology in Drug Development, 2014, v. 3, n. 5, p. 378, doi. 10.1002/cpdd.107
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- Article
A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep).
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- Scandinavian Journal of Pain, 2018, v. 18, n. 2, p. 151, doi. 10.1515/sjpain-2017-0184
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- Article
A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis.
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- Scandinavian Journal of Pain, 2017, v. 17, n. 1, p. 134, doi. 10.1016/j.sjpain.2017.07.021
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- Article
Pharmacokinetics and safety of adjunctive topiramate in infants (1-24 months) with refractory partial-onset seizures: A randomized, multicenter, open-label phase 1 study.
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- Epilepsia (Series 4), 2013, v. 54, n. 1, p. 156, doi. 10.1111/epi.12019
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- Article
Long-Term Open-Label Study of Adjunctive Topiramate in Infants With Refractory Partial-Onset Seizures.
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- Journal of Child Neurology, 2011, v. 26, n. 10, p. 1271, doi. 10.1177/0883073811406982
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- Article