Works matching AU Sgourakis, Nikolaos G.

Results: 21

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23225-6

By:

McShan, Andrew C.;
Devlin, Christine A.;
Morozov, Giora I.;
Overall, Sarah A.;
Moschidi, Danai;
Akella, Neha;
Procko, Erik;
Sgourakis, Nikolaos G.

Publication type:

Article

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01657

By:

Natarajan, Kannan;
Jiang, Jiansheng;
May, Nathan A.;
Mage, Michael G.;
Boyd, Lisa F.;
McShan, Andrew C.;
Sgourakis, Nikolaos G.;
Bax, Ad;
Margulies, David H.

Publication type:

Article

A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00099

By:

Toor, Jugmohit S.;
Rao, Arjun A.;
McShan, Andrew C.;
Yarmarkovich, Mark;
Nerli, Santrupti;
Yamaguchi, Karissa;
Madejska, Ada A.;
Nguyen, Son;
Tripathi, Sarvind;
Maris, John M.;
Salama, Sofie R.;
Haussler, David;
Sgourakis, Nikolaos G.

Publication type:

Article

Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33153-8

By:

Jiang, Jiansheng;
Taylor, Daniel K.;
Kim, Ellen J.;
Boyd, Lisa F.;
Ahmad, Javeed;
Mage, Michael G.;
Truong, Hau V.;
Woodward, Claire H.;
Sgourakis, Nikolaos G.;
Cresswell, Peter;
Margulies, David H.;
Natarajan, Kannan

Publication type:

Article

Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43654-9

By:

McShan, Andrew C.;
Flores-Solis, David;
Sun, Yi;
Garfinkle, Samuel E.;
Toor, Jugmohit S.;
Young, Michael C.;
Sgourakis, Nikolaos G.

Publication type:

Article

HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42163-z

By:

Gupta, Sagar;
Nerli, Santrupti;
Kutti Kandy, Sreeja;
Mersky, Glenn L.;
Sgourakis, Nikolaos G.

Publication type:

Article

A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.

Published in:

Proteins, 2015, v. 83, n. 2, p. 309, doi. 10.1002/prot.24719

By:

Rossi, Paolo;
Shi, Lei;
Liu, Gaohua;
Barbieri, Christopher M.;
Lee, Hsiau‐Wei;
Grant, Thomas D.;
Luft, Joseph R.;
Xiao, Rong;
Acton, Thomas B.;
Snell, Edward H.;
Montelione, Gaetano T.;
Baker, David;
Lange, Oliver F.;
Sgourakis, Nikolaos G.

Publication type:

Article

A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly.

Published in:

PLoS Pathogens, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.ppat.1003307

By:

Bergeron, Julien R. C.;
Worrall, Liam J.;
Sgourakis, Nikolaos G.;
DiMaio, Frank;
Pfuetzner, Richard A.;
Felise, Heather B.;
Vuckovic, Marija;
Yu, Angel C.;
Miller, Samuel I.;
Baker, David;
Strynadka, Natalie C. J.

Publication type:

Article

The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles.

Published in:

PLoS Pathogens, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.ppat.1003245

By:

Demers, Jean-Philippe;
Sgourakis, Nikolaos G.;
Gupta, Rashmi;
Loquet, Antoine;
Giller, Karin;
Riedel, Dietmar;
Laube, Britta;
Kolbe, Michael;
Baker, David;
Becker, Stefan;
Lange, Adam

Publication type:

Article

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15260, doi. 10.1038/ncomms15260

By:

Natarajan, Kannan;
McShan, Andrew C.;
Jiang, Jiansheng;
Kumirov, Vlad K;
Wang, Rui;
Zhao, Huaying;
Schuck, Peter;
Tilahun, Mulualem E.;
Boyd, Lisa F.;
Ying, Jinfa;
Bax, Ad;
Margulies, David H.;
Sgourakis, Nikolaos G.

Publication type:

Article

High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy.

Published in:

Nature Communications, 2014, v. 5, n. 9, p. 4976, doi. 10.1038/ncomms5976

By:

Demers, Jean-Philippe;
Habenstein, Birgit;
Loquet, Antoine;
Kumar Vasa, Suresh;
Giller, Karin;
Becker, Stefan;
Baker, David;
Lange, Adam;
Sgourakis, Nikolaos G.

Publication type:

Article

A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models.

Published in:

BMC Bioinformatics, 2005, v. 6, p. 104, doi. 10.1186/1471-2105-6-104

By:

Sgourakis, Nikolaos G.;
Bagos, Pantelis G.;
Papasaikas, Panagiotis K.;
Hamodrakas, Stavros J.

Publication type:

Article

Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02592-z

By:

Evangelidis, Thomas;
Nerli, Santrupti;
Nováček, Jiří;
Brereton, Andrew E.;
Karplus, P. Andrew;
Dotas, Rochelle R.;
Venditti, Vincenzo;
Sgourakis, Nikolaos G.;
Tripsianes, Konstantinos

Publication type:

Article

Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.

Published in:

Science Immunology, 2023, v. 8, n. 90, p. 1, doi. 10.1126/sciimmunol.adj5792

By:

Sun, Yi;
Florio, Tyler J.;
Gupta, Sagar;
Young, Michael C.;
Marshall, Quinlen F.;
Garfinkle, Samuel E.;
Papadaki, Georgia F.;
Truong, Hau V.;
Mycek, Emily;
Li, Peiyao;
Farrel, Alvin;
Church, Nicole L.;
Jabar, Shereen;
Beasley, Matthew D.;
Kiefel, Ben R.;
Yarmarkovich, Mark;
Mallik, Leena;
Maris, John M.;
Sgourakis, Nikolaos G.

Publication type:

Article

Backbone-independent NMR resonance assignments of methyl probes in large proteins.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-20984-0

By:

Nerli, Santrupti;
De Paula, Viviane S.;
McShan, Andrew C.;
Sgourakis, Nikolaos G.

Publication type:

Article

Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19325-4

By:

Behera, Soumya P.;
Dubey, Abhinav;
Chen, Wan-Na;
De Paula, Viviane S.;
Zhang, Meng;
Sgourakis, Nikolaos G.;
Bermel, Wolfgang;
Wagner, Gerhard;
Coote, Paul W.;
Arthanari, Haribabu

Publication type:

Article

High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15710-1

By:

Overall, Sarah A.;
Toor, Jugmohit S.;
Hao, Stephanie;
Yarmarkovich, Mark;
Sara M. O'Rourke;
Morozov, Giora I.;
Nguyen, Son;
Japp, Alberto Sada;
Gonzalez, Nicolas;
Moschidi, Danai;
Betts, Michael R.;
Maris, John M.;
Smibert, Peter;
Sgourakis, Nikolaos G.

Publication type:

Article

Corrigendum: Atomic model of the type III secretion system needle.

Published in:

2012

By:

Loquet, Antoine;
Sgourakis, Nikolaos G.;
Gupta, Rashmi;
Giller, Karin;
Riedel, Dietmar;
Goosmann, Christian;
Griesinger, Christian;
Kolbe, Michael;
Baker, David;
Becker, Stefan;
Lange, Adam

Publication type:

Erratum

Atomic model of the type III secretion system needle.

Published in:

Nature, 2012, v. 486, n. 7402, p. 276, doi. 10.1038/nature11079

By:

Loquet, Antoine;
Sgourakis, Nikolaos G.;
Gupta, Rashmi;
Giller, Karin;
Riedel, Dietmar;
Goosmann, Christian;
Griesinger, Christian;
Kolbe, Michael;
Baker, David;
Becker, Stefan;
Lange, Adam

Publication type:

Article

Production of soluble pMHC-I molecules in mammalian cells using the molecular chaperone TAPBPR.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 12, p. 525, doi. 10.1093/protein/gzaa015

By:

O'Rourke, Sara M;
Morozov, Giora I;
Roberts, Jacob T;
Barb, Adam W;
Sgourakis, Nikolaos G

Publication type:

Article

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1116906

By:

Papadaki, Georgia F.;
Ani, Omar;
Florio, Tyler J.;
Young, Michael C.;
Danon, Julia N.;
Yi Sun;
Dersh, Devin;
Sgourakis, Nikolaos G.

Publication type:

Article