Works by Sezerman, Osman Ugur

Results: 45

Pathway-Specific Insights into Colorectal Cancer Through Comprehensive Multi-Omics Data Integration.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 468, doi. 10.3390/biology14050468

By:

Karaman, Tayyip;
Oktem Okullu, Sinem;
Bayram Akçapınar, Günseli;
Sezerman, Osman Ugur

Publication type:

Article

PANOGA: a web server for identification of SNP-targeted pathways from genome-wide association study data.

Published in:

Bioinformatics, 2014, v. 30, n. 9, p. 1287, doi. 10.1093/bioinformatics/btt743

By:

Bakir-Gungor, Burcu;
Egemen, Ece;
Sezerman, Osman Ugur

Publication type:

Article

Identification of epilepsy related pathways using genome-wide DNA methylation measures: A trio-based approach.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211917

By:

Ozdemir, Ozkan;
Egemen, Ece;
Ugur Iseri, Sibel Aylin;
Sezerman, Osman Ugur;
Bebek, Nerses;
Baykan, Betul;
Ozbek, Ugur

Publication type:

Article

Is cutaneous microbiota a player in disease pathogenesis? Comparison of cutaneous microbiota in psoriasis and seborrheic dermatitis with scalp involvement.

Published in:

Indian Journal of Dermatology, Venereology & Leprology, 2022, v. 88, n. 6, p. 738, doi. 10.25259/IJDVL_323_21

By:

Kayıran, Melek Aslan;
Sahin, Eray;
Koçoğlu, Esra;
Sezerman, Osman Uğur;
Gürel, Mehmet Salih;
Karadağ, Ayşe Serap

Publication type:

Article

A comparison of various feature extraction and machine learning methods for antimicrobial resistance prediction in streptococcus pneumoniae.

Published in:

Frontiers in Antibiotics, 2023, v. 2, p. 1, doi. 10.3389/frabi.2023.1126468

By:

Kaya, Deniz Ece;
Ülgen, Ege;
Kocagöz, Ayşe Sesin;
Sezerman, Osman Uğur

Publication type:

Article

SARS-CoV-2 isolation and propagation from Turkish COVID-19 patients.

Published in:

Turkish Journal of Biology, 2020, v. 44, n. SI-1, p. 192, doi. 10.3906/biy-2004-113

By:

TAŞTAN, Cihan;
YURTSEVER, Bulut;
SIR KARAKUŞ, Gözde;
DİLEK KANÇAĞI, Derya;
DEMİR, Sevda;
ABANUZ, Selen;
SEYİS, Utku;
YILDIRIM, Mülazim;
KUZAY, Recai;
ELİBOL, Ömer;
ARBAK, Serap;
AÇIKEL ELMAS, Merve;
BİRDOĞAN, Selçuk;
SEZERMAN, Osman Uğur;
KOCAGÖZ, Ayşe Sesin;
YALÇIN, Koray;
OVALI, Ercüment

Publication type:

Article

Investigation of the Impact of Antibiotic Administration on the Preterm Infants' Gut Microbiome Using Next-Generation Sequencing—Based 16S rRNA Gene Analysis.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 10, p. 977, doi. 10.3390/antibiotics13100977

By:

Aktaş, Ahmet;
Ekren, Berkay Yekta;
Yaşa, Beril;
Sezerman, Osman Uğur;
Nakipoğlu, Yaşar

Publication type:

Article

Enhancing Enzymatic Properties of Endoglucanase I Enzyme from Trichoderma Reesei via Swapping from Cellobiohydrolase I Enzyme.

Published in:

Catalysts (2073-4344), 2019, v. 9, n. 2, p. 130, doi. 10.3390/catal9020130

By:

Yenenler, Aslı;
Kurt, Hasan;
Sezerman, Osman Uğur

Publication type:

Article

<i>MIR376A</i> Is a Regulator of Starvation-Induced Autophagy.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082556

By:

Korkmaz, Gozde;
Tekirdag, Kumsal Ayse;
Ozturk, Deniz Gulfem;
Kosar, Ali;
Sezerman, Osman Ugur;
Gozuacik, Devrim

Publication type:

Article

The Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057022

By:

Bakir-Gungor, Burcu;
Sezerman, Osman Ugur

Publication type:

Article

A New Methodology to Associate SNPs with Human Diseases According to Their Pathway Related Context.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026277

By:

Bakir-Gungor, Burcu;
Sezerman, Osman Ugur

Publication type:

Article

Structural characterization of recombinant bovine Goα by spectroscopy and homology modeling.

Published in:

Spectroscopy: An International Journal, 2011, v. 26, n. 4/5, p. 213, doi. 10.1155/2011/808037

By:

Mega Tiber, Pinar;
Orun, Oya;
Nacar, Cevdet;
Sezerman, Ugur Osman;
Severcan, Feride;
Severcan, Mete;
Matagne, André;
Kan, Beki

Publication type:

Article

A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome.

Published in:

Clinical Genetics, 2022, v. 101, n. 3, p. 346, doi. 10.1111/cge.14105

By:

Canpolat, Nur;
Liu, Dingxiao;
Atayar, Emine;
Saygili, Seha;
Kara, Nazli Sila;
Westfall, Trudi A.;
Ding, Qiong;
Brown, Bartley J.;
Braun, Terry A.;
Slusarski, Diane;
Karli Oguz, Kader;
Ozluk, Yasemin;
Tuysuz, Beyhan;
Tastemel Ozturk, Tugba;
Sever, Lale;
Sezerman, Osman Ugur;
Topaloglu, Rezan;
Caliskan, Salim;
Attanasio, Massimo;
Ozaltin, Fatih

Publication type:

Article

Understanding thermal and organic solvent stability of thermoalkalophilic lipases: insights from computational predictions and experiments.

Published in:

Journal of Molecular Modeling, 2020, v. 26, n. 6, p. 1, doi. 10.1007/s00894-020-04396-3

By:

Shehata, Mohamed;
Timucin, Emel;
Venturini, Alessandro;
Sezerman, Osman Uğur

Publication type:

Article

Investigating the structural properties of the active conformation BTL2 of a lipase from Geobacillus thermocatenulatus in toluene using molecular dynamic simulations and engineering BTL2 via in-silico mutation.

Published in:

Journal of Molecular Modeling, 2018, v. 24, n. 9, p. 1, doi. 10.1007/s00894-018-3753-1

By:

Yenenler, Aslı;
Venturini, Alessandro;
Burduroglu, Huseyin Cahit;
Sezerman, Osman Uğur

Publication type:

Article

Prediction of neddylation sites from protein sequences and sequence-derived properties.

Published in:

BMC Bioinformatics, 2015, v. 16, p. 1, doi. 10.1186/1471-2105-16-S18-S9

By:

Yavuz, Ahmet Sinan;
Sözer, Namık Berk;
Sezerman, Osman Uğur

Publication type:

Article

Longitudinal non-targeted metabolomic profiling of urine samples for monitoring of kidney transplantation patients.

Published in:

Renal Failure, 2024, v. 46, n. 2, p. 1, doi. 10.1080/0886022X.2023.2300736

By:

Yozgat, Ihsan;
Cakır, Ulkem;
Serdar, Muhittin Abdulkadir;
Sahin, Sevgi;
Sezerman, Osman Ugur;
Nemutlu, Emirhan;
Baykal, Ahmet Tarik;
Serteser, Mustafa

Publication type:

Article

Longitudinal non-targeted metabolomic profiling of urine samples for monitoring of kidney transplantation patients.

Published in:

Renal Failure, 2024, v. 46, n. 1, p. 1, doi. 10.1080/0886022X.2023.2300736

By:

Yozgat, Ihsan;
Cakır, Ulkem;
Serdar, Muhittin Abdulkadir;
Sahin, Sevgi;
Sezerman, Osman Ugur;
Nemutlu, Emirhan;
Baykal, Ahmet Tarik;
Serteser, Mustafa

Publication type:

Article

Ligand binding pocket of a novel Allatostatin receptor type C of stick insect, Carausius morosus.

Published in:

Scientific Reports, 2017, p. 41266, doi. 10.1038/srep41266

By:

Duan Sahbaz, Burcin;
Sezerman, Osman Ugur;
Torun, Hamdi;
Birgül Iyison, Necla

Publication type:

Article

Var3PPred: variant prediction based on 3-D structure and sequence analyses of protein-protein interactions on autoinflammatory diseases.

Published in:

PeerJ, 2024, p. 1, doi. 10.7717/peerj.17297

By:

Bülbül, Alper;
Timucin, Emel;
Timuçin, Ahmet Can;
Sezerman, Osman Uğur;
Tahir Turanli, Eda

Publication type:

Article

Structural analysis of M1AP variants associated with severely impaired spermatogenesis causing male infertility.

Published in:

PeerJ, 2022, p. 1, doi. 10.7717/peerj.12947

By:

Gerlevik, Umut;
Ergoren, Mahmut Cerkez;
Sezerman, Osman Uğur;
Temel, Sehime Gulsun

Publication type:

Article

Investigation of multiple sclerosis-related pathways through the integration of genomic and proteomic data.

Published in:

PeerJ, 2021, p. 1, doi. 10.7717/peerj.11922

By:

Everest, Elif;
Ülgen, Ege;
Uygunoglu, Ugur;
Tutuncu, Melih;
Saip, Sabahattin;
Sezerman, Osman Uğur;
Siva, Aksel;
Turanli, Eda Tahir

Publication type:

Article

Probing the Structural Dynamics of the Catalytic Domain of Human Soluble Guanylate Cyclase.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-66310-4

By:

Khalid, Rana Rehan;
Maryam, Arooma;
Sezerman, Osman Ugur;
Mylonas, Efstratios;
Siddiqi, Abdul Rauf;
Kokkinidis, Michael

Publication type:

Article

Effect of the switch status of Helicobacter pylori outer inflammatory protein A on gastric diseases.

Published in:

AMB Express, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13568-023-01621-z

By:

Oktem-Okullu, Sinem;
Karaman, Tayyip;
Akcelik-Deveci, Sümeyye;
Timucin, Emel;
Sezerman, Osman Ugur;
Mansur-Ozen, Nesteren;
Buyukcolak, Yaren;
Tiftikci, Arzu

Publication type:

Article

High‐throughput profiling reveals perturbation of endoplasmic reticulum stress‐related genes in atherosclerosis induced by high‐cholesterol diet and the protective role of vitamin E.

Published in:

Biofactors, 2020, v. 46, n. 4, p. 653, doi. 10.1002/biof.1635

By:

Bozaykut, Perinur;
Ekren, Ruchan;
Sezerman, Osman Ugur;
Gladyshev, Vadim N.;
Ozer, Nesrin Kartal

Publication type:

Article

Reply to Stoimenis et al.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 10, p. 1280, doi. 10.1038/ejhg.2014.288

By:

Bakir-Gungor, Burcu;
Remmers, Elaine F;
Meguro, Akira;
Mizuki, Nobuhisa;
Kastner, Daniel L;
Gul, Ahmet;
Sezerman, Osman Ugur

Publication type:

Article

Predicting sumoylation sites using support vector machines based on various sequence features, conformational flexibility and disorder.

Published in:

BMC Genomics, 2014, v. 15, p. 1, doi. 10.1186/1471-2164-15-S9-S18

By:

Yavuz, Ahmet Sinan;
Sezerman, Osman Ugur

Publication type:

Article

The Metabolic Profile of Plasma During Epileptogenesis in a Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy.

Published in:

Molecular Neurobiology, 2025, v. 62, n. 6, p. 7469, doi. 10.1007/s12035-025-04719-6

By:

Antmen, Fatma Merve;
Matpan, Emir;
Dayanc, Ekin Dongel;
Savas, Eylem Ozge;
Eken, Yunus;
Acar, Dilan;
Ak, Alara;
Ozefe, Begum;
Sakar, Damla;
Canozer, Ufuk;
Sancak, Sehla Nurefsan;
Ozdemir, Ozkan;
Sezerman, Osman Ugur;
Baykal, Ahmet Tarık;
Serteser, Mustafa;
Suyen, Guldal

Publication type:

Article

3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cells.

Published in:

Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01611-3

By:

Almeric, Elanur;
Karagozoglu, Deniz;
Cicek, Mustafa;
Dioken, Didem Naz;
Tac, Huseyin Avni;
Cicek, Esra;
Kirim, Busra Aytul;
Gurcuoglu, Irmak;
Sezerman, Osman Ugur;
Ozlu, Nurhan;
Erson-Bensan, Ayse Elif

Publication type:

Article

A collaborative network analysis for the interpretation of transcriptomics data in Huntington's disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-85580-4

By:

Ozisik, Ozan;
Kara, Nazli Sila;
Abbassi-Daloii, Tooba;
Térézol, Morgane;
Kuijper, Elsa C.;
Queralt-Rosinach, Núria;
Jacobsen, Annika;
Sezerman, Osman Ugur;
Roos, Marco;
Evelo, Chris T.;
Baudot, Anaïs;
Ehrhart, Friederike;
Mina, Eleni

Publication type:

Article

Computational approaches for de novo design and redesign of metal-binding sites on proteins.

Published in:

Bioscience Reports, 2017, v. 37, n. 2, p. 1, doi. 10.1042/BSR20160179

By:

Akcapinar, Gunseli Bayram;
Sezerman, Osman Ugur

Publication type:

Article

Urinary Metabolic Profiling During Epileptogenesis in Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy.

Published in:

Biomedicines, 2025, v. 13, n. 3, p. 588, doi. 10.3390/biomedicines13030588

By:

Antmen, Fatma Merve;
Matpan, Emir;
Dongel Dayanc, Ekin;
Savas, Eylem Ozge;
Eken, Yunus;
Acar, Dilan;
Ak, Alara;
Ozefe, Begum;
Sakar, Damla;
Canozer, Ufuk;
Sancak, Sehla Nurefsan;
Ozdemir, Ozkan;
Sezerman, Osman Ugur;
Baykal, Ahmet Tarık;
Serteser, Mustafa;
Suyen, Guldal

Publication type:

Article

Design and characterizations of two novel cellulases through single-gene shuffling of Cel12A (EG3) gene from Trichoderma reseei.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 6, p. 219, doi. 10.1093/protein/gzw011

By:

Yenenler, Aslı;
Sezerman, Osman Uğur

Publication type:

Article

Adaptive phenotypic modulations lead to therapy resistance in chronic myeloid leukemia cells.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0229104

By:

Baykal-Köse, Seda;
Acikgoz, Eda;
Yavuz, Ahmet Sinan;
Gönül Geyik, Öykü;
Ateş, Halil;
Sezerman, Osman Uğur;
Özsan, Güner Hayri;
Yüce, Zeynep

Publication type:

Article

Metabolomic Analyses to Identify Candidate Biomarkers of Cystinosis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2603, doi. 10.3390/ijms24032603

By:

Nemutlu, Emirhan;
Ozaltin, Fatih;
Yabanoglu-Ciftci, Samiye;
Gulhan, Bora;
Eylem, Cemil Can;
Baysal, İpek;
Gök-Topak, Elif Damla;
Ulubayram, Kezban;
Sezerman, Osman Ugur;
Ucar, Gulberk;
Kır, Sedef;
Topaloglu, Rezan

Publication type:

Article

Prediction of peptides binding to MHC class I and II alleles by temporal motif mining.

Published in:

BMC Bioinformatics, 2013, v. 14, n. Suppl 2, p. 1, doi. 10.1186/1471-2105-14-S2-S13

By:

Meydan, Cem;
Otu, Hasan H.;
Sezerman, Osman Uğur

Publication type:

Article

A microdeletion event at 19q13.43 in IDH-mutant astrocytomas is strongly correlated with MYC overexpression.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01811-1

By:

Ülgen, Ege;
Gerlevik, Umut;
Gerlevik, Sıla;
Oktay, Yavuz;
Sezerman, Osman Uğur;
Turcan, Şevin;
Ozduman, Koray

Publication type:

Article

pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks.

Published in:

Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00858

By:

Ulgen, Ege;
Ozisik, Ozan;
Sezerman, Osman Ugur

Publication type:

Article

Computational analysis of missense filamin-A variants, including the novel p.Arg484Gln variant of two brothers with periventricular nodular heterotopia.

Published in:

PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0265400

By:

Gerlevik, Umut;
Saygı, Ceren;
Cangül, Hakan;
Kutlu, Aslı;
Çaralan, Erdal Fırat;
Topçu, Yasemin;
Özören, Nesrin;
Sezerman, Osman Uğur

Publication type:

Article

Identifying and elucidating the roles of Y198N and Y204F mutations in the PAH enzyme through molecular dynamic simulations.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 19, p. 9018, doi. 10.1080/07391102.2021.1921619

By:

Aslan, Tolga;
Yenenler-Kutlu, Aslı;
Gerlevik, Umut;
Aktuğlu Zeybek, Ayşe Çiğdem;
Kıykım, Ertuğrul;
Sezerman, Osman Uğur;
Birgul Iyison, Necla

Publication type:

Article

A recursive molecular docking coupled with energy-based pose-rescoring and MD simulations to identify hsGC βH-NOX allosteric modulators for cardiovascular dysfunctions.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 13, p. 6128, doi. 10.1080/07391102.2021.1877818

By:

Khalid, Rana Rehan;
Maryam, Arooma;
Çınaroğlu, Süleyman Selim;
Siddiqi, Abdul Rauf;
Sezerman, Osman Ugur

Publication type:

Article

A comprehensive study on identifying the structural and functional SNPs of human neuronal membrane glycoprotein M6A (GPM6A).

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 8, p. 2693, doi. 10.1080/07391102.2020.1751712

By:

Khalid, Zoya;
Sezerman, Osman Ugur

Publication type:

Article

APPLICATION OF AUTOMATIC MUTATION–GENE PAIR EXTRACTION TO DISEASES.

Published in:

Journal of Bioinformatics & Computational Biology, 2007, v. 5, n. 6, p. 1261, doi. 10.1142/S021972000700317X

By:

ERDOGMUS, MUGE;
SEZERMAN, OSMAN UGUR

Publication type:

Article

Understanding the Role of the Microbiome in Cancer Diagnostics and Therapeutics by Creating and Utilizing ML Models.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 9, p. N.PAG, doi. 10.3390/app12094094

By:

Cekikj, Miodrag;
Jakimovska Özdemir, Milena;
Kalajdzhiski, Slobodan;
Özcan, Orhan;
Sezerman, Osman Uğur

Publication type:

Article

Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5.

Published in:

Proteins, 2016, v. 84, n. 1, p. 129, doi. 10.1002/prot.24961

By:

Timucin, Emel;
Cousido‐Siah, Alexandra;
Mitschler, André;
Podjarny, Alberto;
Sezerman, Osman Ugur

Publication type:

Article