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RNA-binding protein RBM3 intrinsically suppresses lung innate lymphoid cell activation and inflammation partially through CysLT1R.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32176-5
By:
- Badrani, Jana H.;
- Strohm, Allyssa N.;
- Lacasa, Lee;
- Civello, Blake;
- Cavagnero, Kellen;
- Haung, Yung-An;
- Amadeo, Michael;
- Naji, Luay H.;
- Lund, Sean J.;
- Leng, Anthea;
- Kim, Hyojoung;
- Baum, Rachel E.;
- Khorram, Naseem;
- Mondal, Monalisa;
- Seumois, Grégory;
- Pilotte, Julie;
- Vanderklish, Peter W.;
- McGee, Heather M.;
- Doherty, Taylor A.
Publication type:
Article
Late-rising CD4 T cells resolve mouse cytomegalovirus persistent replication in the salivary gland.
Published in:
PLoS Pathogens, 2024, v. 20, n. 1, p. 1, doi. 10.1371/journal.ppat.1011852
By:
- Brunel, Simon;
- Picarda, Gaelle;
- Gupta, Ankan;
- Ghosh, Raima;
- McDonald, Bryan;
- El Morabiti, Rachid;
- Jiang, Wenjin;
- Greenbaum, Jason A.;
- Adler, Barbara;
- Seumois, Gregory;
- Croft, Michael;
- Vijayanand, Pandurangan;
- Benedict, Chris A.
Publication type:
Article
Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity.
Published in:
Vaccines, 2022, v. 10, n. 4, p. N.PAG, doi. 10.3390/vaccines10040612
By:
- Grifoni, Alba;
- Voic, Hannah;
- Yu, Esther Dawen;
- Mateus, Jose;
- Yan Fung, Kai Mei;
- Wang, Alice;
- Seumois, Grégory;
- De Silva, Aruna D.;
- Tennekon, Rashika;
- Premawansa, Sunil;
- Premawansa, Gayani;
- Tippalagama, Rashmi;
- Wijewickrama, Ananda;
- Chawla, Ashu;
- Greenbaum, Jason;
- Peters, Bjoern;
- Pandurangan, Vijayanand;
- Weiskopf, Daniela;
- Sette, Alessandro
Publication type:
Article
EGF-Induced Bronchial Epithelial Cells Drive Neutrophil Chemotactic and Anti-Apoptotic Activity in Asthma.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0072502
By:
- Uddin, Mohib;
- Lau, Laurie C.;
- Seumois, Grégory;
- Vijayanand, Pandurangan;
- Staples, Karl J.;
- Bagmane, Dinesh;
- Cornelius, Victoria;
- Dorinsky, Paul;
- Davies, Donna E.;
- Djukanović, Ratko
Publication type:
Article
Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054359
By:
- Gerasimova, Anna;
- Chavez, Lukas;
- Bin Li;
- Seumois, Gregory;
- Greenbaum, Jason;
- Rao, Anjana;
- Vijayanand, Pandurangan;
- Peters, Bjoern
Publication type:
Article
Differential Recognition of Mycobacterium tuberculosis-Specific Epitopes as a Function of Tuberculosis Disease History.
Published in:
2017
By:
- Scriba, Thomas J.;
- Carpenter, Chelsea;
- Pro, Sebastian Carrasco;
- Sidney, John;
- Musvosvi, Munyaradzi;
- Rozot, Virginie;
- Seumois, Grégory;
- Rosales, Sandy L.;
- Vijayanand, Pandurangan;
- Goletti, Delia;
- Makgotlho, Edward;
- Hanekom, Willem;
- Hatherill, Mark;
- Peters, Bjoern;
- Sette, Alessandro;
- Arlehamn, Cecilia S. Lindestam
Publication type:
journal article
Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis.
Published in:
Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02633
By:
- Hydes, Theresa J.;
- Blunt, Matthew D.;
- Naftel, Jennifer;
- Vallejo, Andres F.;
- Seumois, Grégory;
- Wang, Alice;
- Vijayanand, Pandurangan;
- Polak, Marta E.;
- Khakoo, Salim I.
Publication type:
Article
How Does Mild Asthma Differ Phenotypically from Difficult-to-Treat Asthma?
Published in:
Journal of Asthma & Allergy, 2023, v. 16, p. 1333, doi. 10.2147/JAA.S430183
By:
- Naftel, Jennifer;
- Mistry, Heena;
- Mitchell, Frances Ann;
- Belson, Jane;
- Kyyaly, Mohammed Aref;
- Barber, Clair;
- Haitchi, Hans Michael;
- Dennison, Paddy;
- Djukanovic, Ratko;
- Seumois, Gregory;
- Vijayanand, Pandurangan;
- Arshad, Syed Hasan;
- Kurukulaaratchy, Ramesh J
Publication type:
Article
The Challenge of Distinguishing Cell–Cell Complexes from Singlet Cells in Non‐Imaging Flow Cytometry and Single‐Cell Sorting.
Published in:
Cytometry. Part A, 2020, v. 97, n. 11, p. 1127, doi. 10.1002/cyto.a.24027
By:
- Burel, Julie G.;
- Pomaznoy, Mikhail;
- Lindestam Arlehamn, Cecilia S.;
- Seumois, Gregory;
- Vijayanand, Pandurangan;
- Sette, Alessandro;
- Peters, Bjoern
Publication type:
Article
Human CD79b+ neutrophils in the blood are associated with early-stage melanoma.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1224045
By:
- Meyer, Melissa A.;
- Dinh, Huy Q.;
- Alimadadi, Ahmad;
- Araujo, Daniel J.;
- Chatterjee, Nandini;
- Gutierrez, Norma A.;
- Zhu, Yanfang Peipei;
- Hunter, Emma L.;
- Shu Liang;
- Seumois, Gregory;
- Kiosses, William B.;
- Catz, Sergio D.;
- Vijayanand, Pandurangan;
- Ottensmeier, Christian;
- Hedrick, Catherine C.
Publication type:
Article
Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis.
Published in:
Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2022.1087010
By:
- Hillman, Hannah;
- Khan, Nabeela;
- Singhania, Akul;
- Dubelko, Paige;
- Soldevila, Ferran;
- Tippalagama, Rashmi;
- DeSilva, Aruna D.;
- Gunasena, Bandu;
- Perera, Judy;
- Scriba, Thomas J.;
- Ontong, Cynthia;
- Fisher, Michelle;
- Luabeya, Angelique;
- Taplitz, Randy;
- Seumois, Gregory;
- Vijayanand, Pandurangan;
- Hedrick, Catherine C.;
- Peters, Bjoern;
- Burel, Julie G.
Publication type:
Article
Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles.
Published in:
2019
By:
- Yuan Tian;
- Babor, Mariana;
- Lane, Jerome;
- Seumois, Grégory;
- Shu Liang;
- Suraj Goonawardhana, N. D.;
- De Silva, Aruna D.;
- Phillips, Elizabeth J.;
- Mallal, Simon A.;
- da Silva Antunes, Ricardo;
- Grifoni, Alba;
- Vijayanand, Pandurangan;
- Weiskopf, Daniela;
- Peters, Bjoern;
- Sette, Alessandro;
- Tian, Yuan;
- Liang, Shu;
- Goonawardhana, N D Suraj
Publication type:
journal article
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Published in:
2019
By:
- Svensson, Mattias N. D.;
- Doody, Karen M.;
- Schmiedel, Benjamin J.;
- Bhattacharyya, Sourya;
- Panwar, Bharat;
- Wiede, Florian;
- Yang, Shen;
- Santelli, Eugenio;
- Wu, Dennis J.;
- Sacchetti, Cristiano;
- Gujar, Ravindra;
- Seumois, Gregory;
- Kiosses, William B.;
- Aubry, Isabelle;
- Kim, Gisen;
- Mydel, Piotr;
- Sakaguchi, Shimon;
- Kronenberg, Mitchell;
- Tiganis, Tony;
- Tremblay, Michel L.
Publication type:
journal article
Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters.
Published in:
2018
By:
- da Silva Antunes, Ricardo;
- Babor, Mariana;
- Carpenter, Chelsea;
- Khalil, Natalie;
- Cortese, Mario;
- Mentzer, Alexander J.;
- Seumois, Grégory;
- Petro, Christopher D.;
- Purcell, Lisa A.;
- Vijayanand, Pandurangan;
- Crotty, Shane;
- Pulendran, Bali;
- Peters, Bjoern;
- Sette, Alessandro
Publication type:
journal article
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility.
Published in:
Nature Immunology, 2014, v. 15, n. 8, p. 777, doi. 10.1038/ni.2937
By:
- Seumois, Grégory;
- Chavez, Lukas;
- Gerasimova, Anna;
- Lienhard, Matthias;
- Omran, Nada;
- Kalinke, Lukas;
- Vedanayagam, Maria;
- Ganesan, Asha Purnima V;
- Chawla, Ashu;
- Djukanović, Ratko;
- Ansel, K Mark;
- Peters, Bjoern;
- Rao, Anjana;
- Vijayanand, Pandurangan
Publication type:
Article
Transcriptomes and metabolism define mouse and human MAIT cell populations.
Published in:
Science Immunology, 2023, v. 8, n. 89, p. 1, doi. 10.1126/sciimmunol.abn8531
By:
- Chandra, Shilpi;
- Ascui, Gabriel;
- Riffelmacher, Thomas;
- Chawla, Ashu;
- Ramírez-Suástegui, Ciro;
- Castelan, Viankail C.;
- Seumois, Gregory;
- Simon, Hayley;
- Murray, Mallory P.;
- Seo, Goo-Young;
- Premlal, Ashmitaa L. R.;
- Schmiedel, Benjamin;
- Verstichel, Greet;
- Li, Yingcong;
- Lin, Chia-Hao;
- Greenbaum, Jason;
- Lamberti, John;
- Murthy, Raghav;
- Nigro, John;
- Cheroutre, Hilde
Publication type:
Article
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants.
Published in:
Science Immunology, 2022, v. 7, n. 68, p. 1, doi. 10.1126/sciimmunol.abm2508
By:
- Schmiedel, Benjamin J.;
- Gonzalez-Colin, Cristian;
- Fajardo, Vicente;
- Rocha, Job;
- Madrigal, Ariel;
- Ramírez-Suástegui, Ciro;
- Bhattacharyya, Sourya;
- Simon, Hayley;
- Greenbaum, Jason A.;
- Peters, Bjoern;
- Seumois, Grégory;
- Ay, Ferhat;
- Chandra, Vivek;
- Vijayanand, Pandurangan
Publication type:
Article
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8+ T cells.
Published in:
Science Immunology, 2021, v. 6, n. 55, p. 1, doi. 10.1126/sciimmunol.abe4782
By:
- Kusnadi, Anthony;
- Ramírez-Suástegui, Ciro;
- Fajardo, Vicente;
- Chee, Serena J.;
- Meckiff, Benjamin J.;
- Simon, Hayley;
- Pelosi, Emanuela;
- Seumois, Grégory;
- Ay, Ferhat;
- Vijayanand, Pandurangan;
- Ottensmeier, Christian H.
Publication type:
Article
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma.
Published in:
Science Immunology, 2020, v. 5, n. 48, p. 1, doi. 10.1126/sciimmunol.aba6087
By:
- Seumois, Grégory;
- Ramírez-Suástegui, Ciro;
- Schmiedel, Benjamin J.;
- Liang, Shu;
- Peters, Bjoern;
- Sette, Alessandro;
- Vijayanand, Pandurangan
Publication type:
Article
Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis.
Published in:
Science Immunology, 2018, v. 3, n. 19, p. 1, doi. 10.1126/sciimmunol.aan8664
By:
- Patil, Veena S.;
- Madrigal, Ariel;
- Schmiedel, Benjamin J.;
- Clarke, James;
- O’Rourke, Patrick;
- de Silva, Aruna D.;
- Harris, Eva;
- Peters, Bjoern;
- Seumois, Gregory;
- Weiskopf, Daniela;
- Sette, Alessandro;
- Vijayanand, Pandurangan
Publication type:
Article
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.
Published in:
Nature Communications, 2016, v. 7, n. 11, p. 13426, doi. 10.1038/ncomms13426
By:
- Schmiedel, Benjamin Joachim;
- Seumois, Grégory;
- Samaniego-Castruita, Daniela;
- Cayford, Justin;
- Schulten, Veronique;
- Chavez, Lukas;
- Ay, Ferhat;
- Sette, Alessandro;
- Peters, Bjoern;
- Vijayanand, Pandurangan
Publication type:
Article
Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells.
Published in:
Science Translational Medicine, 2019, v. 11, n. 478, p. N.PAG, doi. 10.1126/scitranslmed.aau3776
By:
- Dan, Jennifer M.;
- Havenar-Daughton, Colin;
- Kendric, Kayla;
- Al-kolla, Rita;
- Kaushik, Kirti;
- Rosales, Sandy L.;
- Anderson, Ericka L.;
- LaRock, Christopher N.;
- Vijayanand, Pandurangan;
- Seumois, Grégory;
- Layfield, David;
- Cutress, Ramsey I.;
- Ottensmeier, Christian H.;
- Lindestam Arlehamn, Cecilia S.;
- Sette, Alessandro;
- Nizet, Victor;
- Bothwell, Marcella;
- Brigger, Matthew;
- Crotty, Shane
Publication type:
Article
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen.
Published in:
Science Translational Medicine, 2018, v. 10, n. 448, p. 1, doi. 10.1126/scitranslmed.aat0381
By:
- Havenar-Daughton, Colin;
- Sarkar, Anita;
- Kulp, Daniel W.;
- Toy, Laura;
- Hu, Xiaozhen;
- Deresa, Isaiah;
- Kalyuzhniy, Oleksandr;
- Kaushik, Kirti;
- Upadhyay, Amit A.;
- Menis, Sergey;
- Landais, Elise;
- Cao, Liwei;
- Diedrich, Jolene K.;
- Kumar, Sonu;
- Schiffner, Torben;
- Reiss, Samantha M.;
- Seumois, Grégory;
- Yates, John R.;
- Paulson, James C.;
- Bosinger, Steven E.
Publication type:
Article
Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01728-5
By:
- Yuan Tian;
- Babor, Mariana;
- Lane, Jerome;
- Schulten, Veronique;
- Patil, Veena S.;
- Seumois, Grégory;
- Rosales, Sandy L.;
- Burel, Julie;
- Zapardiel-Gonzalo, Jose;
- Vijayanand, Pandurangan;
- Weiskopf, Daniela;
- Sette, Alessandro;
- Peters, Bjoern;
- Tennekoon, Rashika N.;
- De Silva, Aruna D.;
- Zheng Fu;
- Greenbaum, Jason A.;
- Picarda, Gaelle;
- Premawansa, Sunil;
- Premawansa, Gayani
Publication type:
Article
A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer.
Published in:
Science Translational Medicine, 2024, v. 16, n. 736, p. 1, doi. 10.1126/scitranslmed.abj9905
By:
- Miller, Aaron M.;
- Koşaloğlu-Yalçın, Zeynep;
- Westernberg, Luise;
- Montero, Leslie;
- Bahmanof, Milad;
- Frentzen, Angela;
- Lanka, Manasa;
- Logandha Ramamoorthy Premlal, Ashmitaa;
- Seumois, Gregory;
- Greenbaum, Jason;
- Brightman, Spencer E.;
- Soria Zavala, Karla;
- Thota, Rukman R.;
- Naradikian, Martin S.;
- Makani, Samir S.;
- Lippman, Scott M.;
- Sette, Alessandro;
- Cohen, Ezra E. W.;
- Peters, Bjoern;
- Schoenberger, Stephen P.
Publication type:
Article
Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2024, v. 76, n. 8, p. 1243, doi. 10.1002/art.42853
By:
- Van Espen, Benjamin;
- Prideaux, E. Barton;
- Wilson, Andrew R.;
- Machado, Camilla R. L.;
- Sendo, Sho;
- Parker, James;
- Seumois, Grégory;
- Sacchetti, Cristiano;
- Belongia, Anna C.;
- Perumal, Narayanan B.;
- Vijayanand, Pandurangan;
- Linnik, Matthew D.;
- Benschop, Robert J.;
- Wang, Wei;
- Bottini, Nunzio;
- Firestein, Gary S.;
- Stanford, Stephanie M.
Publication type:
Article
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21574-w
By:
- Murray, Mallory Paynich;
- Engel, Isaac;
- Seumois, Grégory;
- Herrera-De la Mata, Sara;
- Rosales, Sandy Lucette;
- Sethi, Ashu;
- Logandha Ramamoorthy Premlal, Ashmitaa;
- Seo, Goo-Young;
- Greenbaum, Jason;
- Vijayanand, Pandurangan;
- Scott-Browne, James P.;
- Kronenberg, Mitchell
Publication type:
Article

Found: 27

RNA-binding protein RBM3 intrinsically suppresses lung innate lymphoid cell activation and inflammation partially through CysLT1R.

Late-rising CD4 T cells resolve mouse cytomegalovirus persistent replication in the salivary gland.

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity.

EGF-Induced Bronchial Epithelial Cells Drive Neutrophil Chemotactic and Anti-Apoptotic Activity in Asthma.

Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data.

Differential Recognition of Mycobacterium tuberculosis-Specific Epitopes as a Function of Tuberculosis Disease History.

Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis.

How Does Mild Asthma Differ Phenotypically from Difficult-to-Treat Asthma?

The Challenge of Distinguishing Cell–Cell Complexes from Singlet Cells in Non‐Imaging Flow Cytometry and Single‐Cell Sorting.

Human CD79b<sup>+</sup> neutrophils in the blood are associated with early-stage melanoma.

Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis.

Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles.

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.

Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters.

Epigenomic analysis of primary human T cells reveals enhancers associated with T<sub>H</sub>2 memory cell differentiation and asthma susceptibility.

Transcriptomes and metabolism define mouse and human MAIT cell populations.

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants.

Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8<sup>+</sup> T cells.

Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma.

Precursors of human CD4<sup>+</sup> cytotoxic T lymphocytes identified by single-cell transcriptome analysis.

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T<sub>FH</sub> cells.

The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen.

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA.

A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer.

Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis.

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure.