Works matching AU Settembre, Carmine

Results: 39

Multiple sulfatase deficiency is due to hypomorphic mutations of the SUMF1 gene.

Published in:

Human Mutation, 2007, v. 28, n. 9, p. 928, doi. 10.1002/humu.9504

By:

Annunziata, Ida;
Bouchè, Valentina;
Lombardi, Alessia;
Settembre, Carmine;
Ballabio, Andrea

Publication type:

Article

Molecular and functional analysis of SUMF1 mutations in multiple sulfatase deficiency.

Published in:

Human Mutation, 2004, v. 23, n. 6, p. 576, doi. 10.1002/humu.20040

By:

Cosma, Maria Pia;
Pepe, Stefano;
Parenti, Giancarlo;
Settembre, Carmine;
Annunziata, Ida;
Wade-Martins, Richard;
Domenico, Carmela Di;
Natale, Paola Di;
Mankad, Anuj;
Cox, Barbara;
Uziel, Graziella;
Mancini, Grazia M.S.;
Zammarchi, Enrico;
Donati, Maria Alice;
Kleijer, Wim J.;
Filocamo, Mirella;
Carrozzo, Romeo;
Carella, Massimo;
Ballabio, Andrea

Publication type:

Article

Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy.

Published in:

EMBO Journal, 2021, v. 40, n. 4, p. 1, doi. 10.15252/embj.2020105120

By:

Morleo, Manuela;
Brillante, Simona;
Formisano, Umberto;
Ferrante, Luigi;
Carbone, Fabrizia;
Iaconis, Daniela;
Palma, Alessandro;
Buonomo, Viviana;
Maione, Angela Serena;
Grumati, Paolo;
Settembre, Carmine;
Franco, Brunella

Publication type:

Article

Beating the ER: novel insights into FAM134B function and regulation.

Published in:

EMBO Journal, 2020, v. 39, n. 5, p. 1, doi. 10.15252/embj.2020104546

By:

De Leonibus, Chiara;
Cinque, Laura;
Settembre, Carmine

Publication type:

Article

TFEB controls vascular development by regulating the proliferation of endothelial cells.

Published in:

EMBO Journal, 2019, v. 38, n. 3, p. 1, doi. 10.15252/embj.201798250

By:

Doronzo, Gabriella;
Astanina, Elena;
Corà, Davide;
Chiabotto, Giulia;
Comunanza, Valentina;
Noghero, Alessio;
Neri, Francesco;
Puliafito, Alberto;
Primo, Luca;
Spampanato, Carmine;
Settembre, Carmine;
Ballabio, Andrea;
Camussi, Giovanni;
Oliviero, Salvatore;
Bussolino, Federico

Publication type:

Article

A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex.

Published in:

EMBO Journal, 2019, v. 38, n. 2, p. N.PAG, doi. 10.15252/embj.201899847

By:

Forrester, Alison;
De Leonibus, Chiara;
Grumati, Paolo;
Fasana, Elisa;
Piemontese, Marilina;
Staiano, Leopoldo;
Fregno, Ilaria;
Raimondi, Andrea;
Marazza, Alessandro;
Bruno, Gemma;
Iavazzo, Maria;
Intartaglia, Daniela;
Seczynska, Marta;
Anken, Eelco;
Conte, Ivan;
De Matteis, Maria Antonietta;
Dikic, Ivan;
Molinari, Maurizio;
Settembre, Carmine

Publication type:

Article

STUB1 regulates TFEB-induced autophagy-lysosome pathway.

Published in:

EMBO Journal, 2017, v. 36, n. 17, p. 2544, doi. 10.15252/embj.201796699

By:

Sha, Youbao;
Rao, Lang;
Settembre, Carmine;
Ballabio, Andrea;
Eissa, N Tony

Publication type:

Article

Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.

Published in:

Autophagy, 2023, v. 19, n. 2, p. 660, doi. 10.1080/15548627.2022.2095791

By:

Akwa, Yvette;
Di Malta, Chiara;
Zallo, Fátima;
Gondard, Elise;
Lunati, Adele;
Diaz-de-Grenu, Lara Z.;
Zampelli, Angela;
Boiret, Anne;
Santamaria, Sara;
Martinez-Preciado, Maialen;
Cortese, Katia;
Kordower, Jeffrey H.;
Matute, Carlos;
Lozano, Andres M.;
Capetillo-Zarate, Estibaliz;
Vaccari, Thomas;
Settembre, Carmine;
Baulieu, Etienne E.;
Tampellini, Davide

Publication type:

Article

Synaptic stimulation induces tau clearance by enhancing autophagosomal/lysosomal degradation.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051678

By:

Akwa, Yvette;
Di Malta, Chiara;
Gondard, Elise;
Boiret, Anne;
Lozano, Andres M;
Vaccari, Thomas;
Settembre, Carmine;
Baulieu, Etienne E;
Tampellini, Davide

Publication type:

Article

Synaptic stimulation protects against pathological tau by enhancing lysosomal degradation: Molecular and cell biology: Tau‐related mechanisms.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040308

By:

Akwa, Yvette;
Gondard, Elise;
Malta, Chiara Di;
Capetillo‐Zarate, Estibaliz;
Boiret, Anne;
Matute, Carlos;
Vaccari, Thomas;
Settembre, Carmine;
Lozano, Andres M.;
Baulieu, Etienne E.;
Tampellini, Davide

Publication type:

Article

T-Cell Protein Tyrosine Phosphatase Regulates Bone Resorption and Whole-Body Insulin Sensitivity through Its Expression in Osteoblasts.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 6, p. 1080, doi. 10.1128/MCB.06279-11

By:

Zee, Tiffany;
Settembre, Carmine;
Levine, Robert L.;
Karsenty, Gerard

Publication type:

Article

Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.

Published in:

EMBO Reports, 2024, v. 25, n. 8, p. 3651, doi. 10.1038/s44319-024-00213-7

By:

Iavarone, Francescopaolo;
Zaninello, Marta;
Perrone, Michela;
Monaco, Mariagrazia;
Barth, Esther;
Gaedke, Felix;
Pizzo, Maria Teresa;
Di Lorenzo, Giorgia;
Desiderio, Vincenzo;
Sommella, Eduardo;
Merciai, Fabrizio;
Salviati, Emanuela;
Campiglia, Pietro;
Luongo, Livio;
De Leonibus, Elvira;
Rugarli, Elena;
Settembre, Carmine

Publication type:

Article

Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER‐phagy, and Collagen quality control.

Published in:

EMBO Reports, 2021, v. 22, n. 9, p. 1, doi. 10.15252/embr.202052289

By:

Reggio, Alessio;
Buonomo, Viviana;
Berkane, Rayene;
Bhaskara, Ramachandra M;
Tellechea, Mariana;
Peluso, Ivana;
Polishchuk, Elena;
Di Lorenzo, Giorgia;
Cirillo, Carmine;
Esposito, Marianna;
Hussain, Adeela;
Huebner, Antje K;
Hübner, Christian A;
Settembre, Carmine;
Hummer, Gerhard;
Grumati, Paolo;
Stolz, Alexandra

Publication type:

Article

A mutation in the ZNF687 gene that is responsible for the severe form of Paget's disease of bone causes severely altered bone remodeling and promotes hepatocellular carcinoma onset in a knock-in mouse model.

Published in:

Bone Research, 2023, v. 11, n. 1, p. 1, doi. 10.1038/s41413-023-00250-3

By:

Russo, Sharon;
Scotto di Carlo, Federica;
Maurizi, Antonio;
Fortunato, Giorgio;
Teti, Anna;
Licastro, Danilo;
Settembre, Carmine;
Mello, Tommaso;
Gianfrancesco, Fernando

Publication type:

Article

A block of autophagy in lysosomal storage disorders.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 1, p. 119, doi. 10.1093/hmg/ddm289

By:

Settembre, Carmine;
Fraldi, Alessandro;
Jahreiss, Luca;
Spampanato, Carmine;
Venturi, Consuelo;
Medina, Diego;
de Pablo, Raquel;
Tacchetti, Carlo;
Rubinsztein, David C.;
Ballabio, Andrea

Publication type:

Article

TFEB regulates murine liver cell fate during development and regeneration.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16300-x

By:

Pastore, Nunzia;
Huynh, Tuong;
Herz, Niculin J.;
Calcagni’, Alessia;
Klisch, Tiemo J.;
Brunetti, Lorenzo;
Kangho Ho Kim;
De Giorgi, Marco;
Hurley, Ayrea;
Carissimo, Annamaria;
Mutarelli, Margherita;
Aleksieva, Niya;
D’Orsi, Luca;
Lagor, William R.;
Moore, David D.;
Settembre, Carmine;
Finegold, Milton J.;
Forbes, Stuart J.;
Ballabio, Andrea

Publication type:

Article

Autophagy gets to the bone.

Published in:

Cell Cycle, 2016, v. 15, n. 7, p. 871, doi. 10.1080/15384101.2016.1151724

By:

Cinque, Laura;
Forrester, Alison;
Settembre, Carmine

Publication type:

Article

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.

Published in:

2017

By:

Bartolomeo, Rosa;
Cinque, Laura;
De Leonibus, Chiara;
Forrester, Alison;
Salzano, Anna Chiara;
Monfregola, Jlenia;
De Gennaro, Emanuela;
Nusco, Edoardo;
Azario, Isabella;
Lanzara, Carmela;
Serafini, Marta;
Levine, Beth;
Ballabio, Andrea;
Settem, Carmine;
Settembre, Carmine

Publication type:

journal article

Current methods to analyze lysosome morphology, positioning, motility and function.

Published in:

Traffic, 2022, v. 23, n. 5, p. 238, doi. 10.1111/tra.12839

By:

Barral, Duarte C.;
Staiano, Leopoldo;
Guimas Almeida, Cláudia;
Cutler, Dan F.;
Eden, Emily R.;
Futter, Clare E.;
Galione, Antony;
Marques, André R. A.;
Medina, Diego Luis;
Napolitano, Gennaro;
Settembre, Carmine;
Vieira, Otília V.;
Aerts, Johannes M. F. G.;
Atakpa‐Adaji, Peace;
Bruno, Gemma;
Capuozzo, Antonella;
De Leonibus, Elvira;
Di Malta, Chiara;
Escrevente, Cristina;
Esposito, Alessandra

Publication type:

Article

Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 2, p. 1, doi. 10.15252/emmm.202013158

By:

Soria, Leandro R;
Gurung, Sonam;
De Sabbata, Giulia;
Perocheau, Dany P;
De Angelis, Angela;
Bruno, Gemma;
Polishchuk, Elena;
Paris, Debora;
Cuomo, Paola;
Motta, Andrea;
Orford, Michael;
Khalil, Youssef;
Eaton, Simon;
Mills, Philippa B;
Waddington, Simon N;
Settembre, Carmine;
Muro, Andrés F;
Baruteau, Julien;
Brunetti‐Pierri, Nicola

Publication type:

Article

New targets for old diseases: lessons from mucolipidosis type II.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 12, p. 1801, doi. 10.1002/emmm.201303496

By:

Settembre, Carmine;
Ballabio, Andrea

Publication type:

Article

Boning up on autophagy.

Published in:

Autophagy, 2014, v. 10, n. 1, p. 7, doi. 10.4161/auto.26679

By:

Shapiro, Irving M.;
Layfield, Robert;
Lotz, Martin;
Settembre, Carmine;
Whitehouse, Caroline

Publication type:

Article

Autophagy in astrocytes.

Published in:

Autophagy, 2012, v. 8, n. 12, p. 1871, doi. 10.4161/auto.22184

By:

Di Malta, Chiara;
Fryer, John D.;
Settembre, Carmine;
Ballabio, Andrea

Publication type:

Article

TFEB regulates autophagy.

Published in:

Autophagy, 2011, v. 7, n. 11, p. 1379, doi. 10.4161/auto.7.11.17166

By:

Settembre, Carmine;
Ballabio, Andrea

Publication type:

Article

Cystic fibrosis.

Published in:

Autophagy, 2011, v. 7, n. 1, p. 104, doi. 10.4161/auto.7.1.13987

By:

Luciani, Alessandro;
Villella, Valeria R.;
Esposito, Speranza;
Brunetti-Pierri, Nicola;
Medina, Diego L.;
Settembre, Carmine;
Gavina, Manuela;
Raia, Valeria;
Ballabio, Andrea;
Maiuri, Luigi

Publication type:

Article

Emerging lysosomal pathways for quality control at the endoplasmic reticulum.

Published in:

FEBS Letters, 2019, v. 593, n. 17, p. 2319, doi. 10.1002/1873-3468.13571

By:

De Leonibus, Chiara;
Cinque, Laura;
Settembre, Carmine

Publication type:

Article

Integrative Multi-Omics Approach in Vascular Ehlers–Danlos Syndrome: Further Insights into the Disease Mechanisms by Proteomic Analysis of Patient Dermal Fibroblasts.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2749, doi. 10.3390/biomedicines12122749

By:

Chiarelli, Nicola;
Cinquina, Valeria;
Zoppi, Nicoletta;
Bertini, Valeria;
Maddaluno, Marianna;
De Leonibus, Chiara;
Settembre, Carmine;
Venturini, Marina;
Colombi, Marina;
Ritelli, Marco

Publication type:

Article

Cell metabolism: Autophagy transcribed.

Published in:

Nature, 2014, v. 516, n. 7529, p. 40, doi. 10.1038/nature13939

By:

Settembre, Carmine;
Ballabio, Andrea

Publication type:

Article

Signals from the lysosome: a control centre for cellular clearance and energy metabolism.

Published in:

Nature Reviews Molecular Cell Biology, 2013, v. 14, n. 5, p. 283, doi. 10.1038/nrm3565

By:

Settembre, Carmine;
Fraldi, Alessandro;
Medina, Diego L.;
Ballabio, Andrea

Publication type:

Article

MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process.

Published in:

Aging Cell, 2022, v. 21, n. 7, p. 1, doi. 10.1111/acel.13620

By:

Franci, Lorenzo;
Tubita, Alessandro;
Bertolino, Franca Maria;
Palma, Alessandro;
Cannino, Giuseppe;
Settembre, Carmine;
Rasola, Andrea;
Rovida, Elisabetta;
Chiariello, Mario

Publication type:

Article

Mechanisms by which autophagy regulates memory capacity in ageing.

Published in:

Aging Cell, 2020, v. 19, n. 9, p. 1, doi. 10.1111/acel.13189

By:

De Risi, Maria;
Torromino, Giulia;
Tufano, Michele;
Moriceau, Stéphanie;
Pignataro, Annabella;
Rivagorda, Manon;
Carrano, Nicolò;
Middei, Silvia;
Settembre, Carmine;
Ammassari‐Teule, Martine;
Gardoni, Fabrizio;
Mele, Andrea;
Oury, Franck;
De Leonibus, Elvira

Publication type:

Article

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.17047

By:

Calcagní, Alessia;
Kors, Lotte;
Verschuren, Eric;
De Cegli, Rossella;
Zampelli, Nicolina;
Nusco, Edoardo;
Confalonieri, Stefano;
Bertalot, Giovanni;
Pece, Salvatore;
Settembre, Carmine;
Malouf, Gabriel G.;
Leemans, Jaklien C.;
de Heer, Emile;
Salvatore, Marco;
Peters, Dorien J. M.;
Di Fiore, Pier Paolo;
Ballabio, Andrea

Publication type:

Article

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

Published in:

Nature Cell Biology, 2015, v. 17, n. 3, p. 288, doi. 10.1038/ncb3114

By:

Medina, Diego L.;
Di Paola, Simone;
Peluso, Ivana;
Armani, Andrea;
De Stefani, Diego;
Venditti, Rossella;
Montefusco, Sandro;
Scotto-Rosato, Anna;
Prezioso, Carolina;
Forrester, Alison;
Settembre, Carmine;
Wang, Wuyang;
Gao, Qiong;
Xu, Haoxing;
Sandri, Marco;
Rizzuto, Rosario;
De Matteis, Maria Antonietta;
Ballabio, Andrea

Publication type:

Article

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.

Published in:

Nature Cell Biology, 2013, v. 15, n. 8, p. 1016, doi. 10.1038/ncb2814

By:

Settembre, Carmine;
De Cegli, Rossella;
Mansueto, Gelsomina;
Saha, Pradip K.;
Vetrini, Francesco;
Visvikis, Orane;
Huynh, Tuong;
Carissimo, Annamaria;
Palmer, Donna;
Klisch, Tiemo Jürgen;
Wollenberg, Amanda C.;
Di Bernardo, Diego;
Chan, Lawrence;
Irazoqui, Javier E.;
Ballabio, Andrea

Publication type:

Article

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.

Published in:

Nature Cell Biology, 2013, v. 15, n. 6, p. 647, doi. 10.1038/ncb2718

By:

Settembre, Carmine;
De Cegli, Rossella;
Mansueto, Gelsomina;
Saha, Pradip K.;
Vetrini, Francesco;
Visvikis, Orane;
Huynh, Tuong;
Carissimo, Annamaria;
Palmer, Donna;
Jürgen Klisch, Tiemo;
Wollenberg, Amanda C.;
Di Bernardo, Diego;
Chan, Lawrence;
Irazoqui, Javier E.;
Ballabio, Andrea

Publication type:

Article

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.

Published in:

Nature Cell Biology, 2010, v. 12, n. 9, p. 863, doi. 10.1038/ncb2090

By:

Luciani, Alessandro;
Villella, Valeria Rachela;
Esposito, Speranza;
Brunetti-Pierri, Nicola;
Medina, Diego;
Settembre, Carmine;
Gavina, Manuela;
Pulze, Laura;
Giardino, Ida;
Pettoello-Mantovani, Massimo;
D'Apolito, Maria;
Guido, Stefano;
Masliah, Eliezer;
Spencer, Brian;
Quaratino, Sonia;
Raia, Valeria;
Ballabio, Andrea;
Maiuri, Luigi

Publication type:

Article

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum.

Published in:

EMBO Journal, 2016, v. 35, n. 23, p. 2614, doi. 10.15252/embj.201670020

By:

Zito, Ester;
Buono, Mario;
Pepe, Stefano;
Settembre, Carmine;
Annunziata, Ida;
Surace, Enrico Maria;
Dierks, Thomas;
Monti, Maria;
Cozzolino, Marianna;
Pucci, Piero;
Ballabio, Andrea;
Cosma, Maria Pia

Publication type:

Article

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.

Published in:

EMBO Journal, 2012, v. 31, n. 5, p. 1095, doi. 10.1038/emboj.2012.32

By:

Settembre, Carmine;
Zoncu, Roberto;
Medina, Diego L;
Vetrini, Francesco;
Erdin, Serkan;
Erdin, SerpilUckac;
Huynh, Tuong;
Ferron, Mathieu;
Karsenty, Gerard;
Vellard, Michel C;
Facchinetti, Valeria;
Sabatini, David M;
Ballabio, Andrea

Publication type:

Article

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum.

Published in:

EMBO Journal, 2007, v. 26, n. 10, p. 2443, doi. 10.1038/sj.emboj.7601695

By:

Zito, Ester;
Buono, Mario;
Pepe, Stefano;
Settembre, Carmine;
Annunziata, Ida;
Surace, Enrico Maria;
Dierks, Thomas;
Monti, Maria;
Cozzolino, Marianna;
Pucci, Piero;
Ballabio, Andrea;
Cosma, Maria Pia

Publication type:

Article