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A mutation in the ZNF687 gene that is responsible for the severe form of Paget's disease of bone causes severely altered bone remodeling and promotes hepatocellular carcinoma onset in a knock-in mouse model.
- Published in:
- Bone Research, 2023, v. 11, n. 1, p. 1, doi. 10.1038/s41413-023-00250-3
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- Article
MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process.
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- Aging Cell, 2022, v. 21, n. 7, p. 1, doi. 10.1111/acel.13620
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- Publication type:
- Article
Current methods to analyze lysosome morphology, positioning, motility and function.
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- Traffic, 2022, v. 23, n. 5, p. 238, doi. 10.1111/tra.12839
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- Article
Synaptic stimulation induces tau clearance by enhancing autophagosomal/lysosomal degradation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051678
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- Article
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER‐phagy, and Collagen quality control.
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- EMBO Reports, 2021, v. 22, n. 9, p. 1, doi. 10.15252/embr.202052289
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- Article
Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy.
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- EMBO Journal, 2021, v. 40, n. 4, p. 1, doi. 10.15252/embj.2020105120
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- Publication type:
- Article
Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders.
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- EMBO Molecular Medicine, 2021, v. 13, n. 2, p. 1, doi. 10.15252/emmm.202013158
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- Article
Synaptic stimulation protects against pathological tau by enhancing lysosomal degradation: Molecular and cell biology: Tau‐related mechanisms.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040308
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- Article
Mechanisms by which autophagy regulates memory capacity in ageing.
- Published in:
- Aging Cell, 2020, v. 19, n. 9, p. 1, doi. 10.1111/acel.13189
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- Article
TFEB regulates murine liver cell fate during development and regeneration.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16300-x
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- Article
Beating the ER: novel insights into FAM134B function and regulation.
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- EMBO Journal, 2020, v. 39, n. 5, p. 1, doi. 10.15252/embj.2020104546
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- Publication type:
- Article
Emerging lysosomal pathways for quality control at the endoplasmic reticulum.
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- FEBS Letters, 2019, v. 593, n. 17, p. 2319, doi. 10.1002/1873-3468.13571
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- Publication type:
- Article
TFEB controls vascular development by regulating the proliferation of endothelial cells.
- Published in:
- EMBO Journal, 2019, v. 38, n. 3, p. 1, doi. 10.15252/embj.201798250
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- Publication type:
- Article
A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex.
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- EMBO Journal, 2019, v. 38, n. 2, p. N.PAG, doi. 10.15252/embj.201899847
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- Article
mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.
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- 2017
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- Publication type:
- journal article
STUB1 regulates TFEB-induced autophagy-lysosome pathway.
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- EMBO Journal, 2017, v. 36, n. 17, p. 2544, doi. 10.15252/embj.201796699
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- Publication type:
- Article
Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum.
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- EMBO Journal, 2016, v. 35, n. 23, p. 2614, doi. 10.15252/embj.201670020
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- Publication type:
- Article
Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.17047
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- Publication type:
- Article
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
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- Nature Cell Biology, 2015, v. 17, n. 3, p. 288, doi. 10.1038/ncb3114
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- Article
Cell metabolism: Autophagy transcribed.
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- Nature, 2014, v. 516, n. 7529, p. 40, doi. 10.1038/nature13939
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- Article
New targets for old diseases: lessons from mucolipidosis type II.
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- EMBO Molecular Medicine, 2013, v. 5, n. 12, p. 1801, doi. 10.1002/emmm.201303496
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- Publication type:
- Article
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
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- Nature Cell Biology, 2013, v. 15, n. 8, p. 1016, doi. 10.1038/ncb2814
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- Publication type:
- Article
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
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- Nature Cell Biology, 2013, v. 15, n. 6, p. 647, doi. 10.1038/ncb2718
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- Publication type:
- Article
Signals from the lysosome: a control centre for cellular clearance and energy metabolism.
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- Nature Reviews Molecular Cell Biology, 2013, v. 14, n. 5, p. 283, doi. 10.1038/nrm3565
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- Publication type:
- Article
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
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- EMBO Journal, 2012, v. 31, n. 5, p. 1095, doi. 10.1038/emboj.2012.32
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- Publication type:
- Article
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
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- Nature Cell Biology, 2010, v. 12, n. 9, p. 863, doi. 10.1038/ncb2090
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- Publication type:
- Article
A block of autophagy in lysosomal storage disorders.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 1, p. 119, doi. 10.1093/hmg/ddm289
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- Publication type:
- Article
Multiple sulfatase deficiency is due to hypomorphic mutations of the SUMF1 gene.
- Published in:
- Human Mutation, 2007, v. 28, n. 9, p. 928, doi. 10.1002/humu.9504
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- Publication type:
- Article
Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum.
- Published in:
- EMBO Journal, 2007, v. 26, n. 10, p. 2443, doi. 10.1038/sj.emboj.7601695
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- Publication type:
- Article
Molecular and functional analysis of SUMF1 mutations in multiple sulfatase deficiency.
- Published in:
- Human Mutation, 2004, v. 23, n. 6, p. 576, doi. 10.1002/humu.20040
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- Publication type:
- Article