OpenURL Connection Search

Select item for more details and to access through your institution.

Phosphoinositide 3-Kinases as Potential Targets for Thrombosis Prevention.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4840, doi. 10.3390/ijms23094840
By:
- Setiabakti, Natasha M.;
- Larsson, Pia;
- Hamilton, Justin R.
Publication type:
Article
The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.
Published in:
Nature Communications, 2015, v. 6, n. 3, p. 6535, doi. 10.1038/ncomms7535
By:
- Mountford, Jessica K.;
- Petitjean, Claire;
- Putra, Harun W. Kusuma;
- McCafferty, Jonathan A.;
- Setiabakti, Natasha M.;
- Lee, Hannah;
- Tønnesen, Lotte L.;
- McFadyen, James D.;
- Schoenwaelder, Simone M.;
- Eckly, Anita;
- Gachet, Christian;
- Ellis, Sarah;
- Voss, Anne K.;
- Dickins, Ross A.;
- Hamilton, Justin R.;
- Jackson, Shaun P.
Publication type:
Article
Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation.
Published in:
Science Translational Medicine, 2020, v. 12, n. 553, p. 1, doi. 10.1126/scitranslmed.aar8430
By:
- Selvadurai, Maria V.;
- Moon, Mitchell J.;
- Mountford, Simon J.;
- Ma, Xiao;
- Zheng, Zhaohua;
- Jennings, Ian G.;
- Setiabakti, Natasha M.;
- Iman, Rizani P.;
- Brazilek, Rose J.;
- Z. Abidin, Nurul Aisha;
- Chicanne, Gaëtan;
- Severin, Sonia;
- Nicholls, Alyce J.;
- Wong, Connie H.Y.;
- Rinckel, Jean-Yves;
- Eckly, Anita;
- Gachet, Christian;
- Nesbitt, Warwick S.;
- Thompson, Philip E.;
- Hamilton, Justin R.
Publication type:
Article

Found: 3

Phosphoinositide 3-Kinases as Potential Targets for Thrombosis Prevention.

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation.