Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.
- Published in:
- Scientific Reports, 2016, p. 24575, doi. 10.1038/srep24575
- By:
- Publication type:
- Article
Works by Seow, Vernon
Results: 3
1
2
Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism.
- Published in:
- FASEB Journal, 2013, v. 27, n. 12, p. 4757, doi. 10.1096/fj.13-232702
- By:
- Publication type:
- Article
3
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.
- Published in:
- FASEB Journal, 2013, v. 27, n. 2, p. 822, doi. 10.1096/fj.12-220582
- By:
- Publication type:
- Article