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Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
Published in:
2020
By:
- Seong Su Kang;
- Xia Liu;
- Eun Hee Ahn;
- Jie Xiang;
- Manfredsson, Fredric P.;
- Xifei Yang;
- Luo, Hongbo R.;
- Liles, L. Cameron;
- Weinshenker, David;
- Keqiang Ye;
- Kang, Seong Su;
- Liu, Xia;
- Ahn, Eun Hee;
- Xiang, Jie;
- Yang, Xifei;
- Ye, Keqiang
Publication type:
journal article
Improved long-term cryostorage ofEscherichia colicompetent cells using trehalose.
Published in:
Biotechnology Letters, 2004, v. 26, n. 20, p. 1593, doi. 10.1023/B:BILE.0000045659.41621.de
By:
- Taeho Ahn;
- Seong Su Kang;
- Chul-Ho Yun
Publication type:
Article
A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer's disease pathologies.
Published in:
2021
By:
- Yao, Yinan;
- Kang, Seong Su;
- Xia, Yiyuan;
- Wang, Zhi-Hao;
- Liu, Xia;
- Muller, Thorsten;
- Sun, Yi E;
- Ye, Keqiang
Publication type:
journal article
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
Published in:
Nature Medicine, 2014, v. 20, n. 11, p. 1254, doi. 10.1038/nm.3700
By:
- Zhang, Zhentao;
- Song, Mingke;
- Yu, Shan Ping;
- Liu, Xia;
- Kang, Seong Su;
- Kwon, Il-Sun;
- Ye, Keqiang;
- Duong, Duc M;
- Seyfried, Nicholas T;
- Hu, William T;
- Liu, Zhixue;
- Wang, Jian-Zhi;
- Cheng, Liming;
- Sun, Yi E;
- Levey, Allan I
Publication type:
Article
Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer's disease.
Published in:
EMBO Journal, 2021, v. 40, n. 17, p. 1, doi. 10.15252/embj.2020106320
By:
- Chen, Chun;
- Zhou, Yunzhe;
- Wang, Hualong;
- Alam, Ashfaqul;
- Kang, Seong Su;
- Ahn, Eun Hee;
- Liu, Xia;
- Jia, Jianping;
- Ye, Keqiang
Publication type:
Article
Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features.
Published in:
EMBO Journal, 2021, v. 40, n. 3, p. 1, doi. 10.15252/embj.2020105537
By:
- Jasmin, Mélissa;
- Ahn, Eun Hee;
- Voutilainen, Merja H;
- Fombonne, Joanna;
- Guix, Catherine;
- Viljakainen, Tuulikki;
- Kang, Seong Su;
- Yu, Li‐ying;
- Saarma, Mart;
- Mehlen, Patrick;
- Ye, Keqiang
Publication type:
Article
Asparagine endopeptidase cleaves amyloid precursor protein and promotes amyloidogenesis in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P858, doi. 10.1016/j.jalz.2015.08.031
By:
- Zhang, Zhentao;
- Song, Mingke;
- Liu, Xia;
- Kang, Seong Su;
- Duong, Duc M.;
- Seyfried, Nicholas T.;
- Cao, Xuebing;
- Cheng, Liming;
- Sun, Yi;
- Yu, Shan-Ping;
- Levey, Allan I.;
- Ye, Keqiang
Publication type:
Article
Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer's disease.
Published in:
Experimental & Molecular Medicine EMM, 2020, v. 52, n. 8, p. 1275, doi. 10.1038/s12276-020-00494-7
By:
- Kang, Seong Su;
- Ahn, Eun Hee;
- Ye, Keqiang
Publication type:
Article
FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42282-7
By:
- Xiong, Jing;
- Kang, Seong Su;
- Wang, Mengmeng;
- Wang, Zhihao;
- Xia, Yiyuan;
- Liao, Jianming;
- Liu, Xia;
- Yu, Shan-Ping;
- Zhang, Zhaohui;
- Ryu, Vitaly;
- Yuen, Tony;
- Zaidi, Mone;
- Ye, Keqiang
Publication type:
Article
Oral Treatments With the TrkB Ligand Prodrug, R13, Promote Enhanced Axon Regeneration Following Peripheral Nerve Injury.
Published in:
Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.857664
By:
- English, Arthur W.;
- Carrasco, Dario;
- Hoffman, Dustin;
- Isaacson, Robin;
- Kang, Seong Su;
- Khan, Samia;
- Liu, Xia;
- Ye, Keqiang
Publication type:
Article
Brain atlas for glycoprotein hormone receptors at single-transcript level.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.79612
By:
- Ryu, Vitaly;
- Gumerova, Anisa;
- Korkmaz, Funda;
- Seong Su Kang;
- Katsel, Pavel;
- Miyashita, Sari;
- Kannangara, Hasni;
- Cullen, Liam;
- Chan, Pokman;
- TanChun Kuo;
- Padilla, Ashley;
- Sultana, Farhath;
- Wizman, Soleil A.;
- Kramskiy, Natan;
- Zaidi, Samir;
- Se-Min Kim;
- New, Maria I.;
- Rosen, Clifford J.;
- Goosens, Ki A.;
- Frolinger, Tal
Publication type:
Article
α‐Synuclein stimulation of monoamine oxidase‐B and legumain protease mediates the pathology of Parkinson's disease.
Published in:
EMBO Journal, 2018, v. 37, n. 12, p. 1, doi. 10.15252/embj.201798878
By:
- Kang, Seong Su;
- Ahn, Eun Hee;
- Zhang, Zhentao;
- Liu, Xia;
- Manfredsson, Fredric P.;
- Sandoval, Ivette M.;
- Dhakal, Susov;
- Iuvone, P. Michael;
- Cao, Xuebing;
- Ye, Keqiang
Publication type:
Article
UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease.
Published in:
Advanced Science, 2022, v. 9, n. 7, p. 1, doi. 10.1002/advs.202103396
By:
- Chen, Guiqin;
- Ahn, Eun Hee;
- Kang, Seong Su;
- Xia, Yiyuan;
- Liu, Xia;
- Zhang, Zhaohui;
- Ye, Keqiang
Publication type:
Article
Short-Term Effect of Biochar on Soil Organic Carbon Improvement and Nitrous Oxide Emission Reduction According to Different Soil Characteristics in Agricultural Land: A Laboratory Experiment.
Published in:
Agronomy, 2022, v. 12, n. 8, p. N.PAG, doi. 10.3390/agronomy12081879
By:
- Lee, Jong-Mun;
- Park, Do-Gyun;
- Kang, Seong-Su;
- Choi, Eun-Jung;
- Gwon, Hyo-Suk;
- Lee, Hyoung-Seok;
- Lee, Sun-Il
Publication type:
Article
Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma in a Child: A Case Report.
Published in:
2020
By:
- Seung Hee Byun;
- Sun Kyoung You;
- Seong Su Kang;
- Kyung Sook Shin;
- Jeong Eun Lee
Publication type:
Case Study
GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression.
Published in:
Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1150399
By:
- Ye Ji Lee;
- Ye Ji Jeong;
- Eun Ji Kang;
- Beom Seok Kang;
- Song Hee Lee;
- You Jin Kim;
- Seong Su Kang;
- Sang Won Suh;
- Eun Hee Ahn
Publication type:
Article
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 422, doi. 10.1172/JCI130513
By:
- Seong Su Kang;
- Xia Liu;
- Eun Hee Ahn;
- Jie Xiang;
- Manfredsson, Fredric P.;
- Xifei Yang;
- Luo, Hongbo R.;
- Liles, L. Cameron;
- Weinshenker, David;
- Keqiang Ye
Publication type:
Article
C/EBPβ/AEP is age-dependently activated in Parkinson's disease and mediates α-synuclein in the gut and brain.
Published in:
NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-022-00430-8
By:
- Wang, Hualong;
- Chen, Guiqin;
- Ahn, Eun Hee;
- Xia, Yiyuan;
- Kang, Seong Su;
- Liu, Xia;
- Liu, Chang;
- Han, Ming-Hu;
- Chen, Shengdi;
- Ye, Keqiang
Publication type:
Article
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14740, doi. 10.1038/ncomms14740
By:
- Zhang, Zhentao;
- Obianyo, Obiamaka;
- Dall, Elfriede;
- Du, Yuhong;
- Fu, Haian;
- Liu, Xia;
- Kang, Seong Su;
- Song, Mingke;
- Yu, Shan-Ping;
- Cabrele, Chiara;
- Schubert, Mario;
- Li, Xiaoguang;
- Wang, Jian-Zhi;
- Brandstetter, Hans;
- Ye, Keqiang
Publication type:
Article
Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.
Published in:
Nature Communications, 2015, v. 6, n. 11, p. 8762, doi. 10.1038/ncomms9762
By:
- Zhang, Zhentao;
- Song, Mingke;
- Liu, Xia;
- Su Kang, Seong;
- Duong, Duc M.;
- Seyfried, Nicholas T.;
- Cao, Xuebing;
- Cheng, Liming;
- Sun, Yi E.;
- Ping Yu, Shan;
- Jia, Jianping;
- Levey, Allan I.;
- Ye, Keqiang
Publication type:
Article
Treatments with the specific δ‐secretase inhibitor, compound 11, promote the regeneration of motor and sensory axons after peripheral nerve injury.
Published in:
European Journal of Neuroscience, 2023, v. 58, n. 6, p. 3555, doi. 10.1111/ejn.16126
By:
- Isaacson, Robin H.;
- Carrasco, Dario I.;
- Holliday, Hannah;
- Kang, Seong Su;
- Khan, Samia;
- Kim, David;
- Liu, Xia;
- Ye, Keqiang;
- English, Arthur W.
Publication type:
Article
ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease.
Published in:
Acta Neuropathologica, 2021, v. 142, n. 1, p. 139, doi. 10.1007/s00401-021-02315-1
By:
- Kang, Seong Su;
- Ahn, Eun Hee;
- Liu, Xia;
- Bryson, Matthew;
- Miller, Gary W.;
- Weinshenker, David;
- Ye, Keqiang
Publication type:
Article
Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease.
Published in:
Journal of Neuroscience, 2019, v. 39, n. 37, p. 7291, doi. 10.1523/JNEUROSCI.0625-19.2019
By:
- Shilin Luo;
- Seong Su Kang;
- Zhi-Hao Wang;
- Xia Liu;
- Julia X. Day;
- Zhiping Wu;
- Junmin Peng;
- Daxiong Xiang;
- Springer, Wolfdieter;
- Keqiang Ye
Publication type:
Article
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma.
Published in:
Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13045-020-00979-y
By:
- Lei, Kecheng;
- Gu, Xiaoxia;
- Alvarado, Alvaro G.;
- Du, Yuhong;
- Luo, Shilin;
- Ahn, Eun Hee;
- Kang, Seong Su;
- Ji, Bing;
- Liu, Xia;
- Mao, Hui;
- Fu, Haian;
- Kornblum, Harley I.;
- Jin, Lingjing;
- Li, Hua;
- Ye, Keqiang
Publication type:
Article
Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression.
Published in:
Cell Communication & Signaling, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1478-811X-11-35
By:
- Keasey, Matthew P.;
- Seong Su Kang;
- Lovins, Chiharu;
- Hagg, Theo
Publication type:
Article
Loss of Neuron-Astroglial Interaction Rapidly Induces Protective CNTF Expression after Stroke in Mice.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 27, p. 9277, doi. 10.1523/JNEUROSCI.1746-12.2012
By:
- Kang, Seong Su;
- Keasey, Matthew P.;
- Cai, Jun;
- Hagg, Theo
Publication type:
Article

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