Works by Senniappan, Senthil

Results: 69

Developing a congenital hyperinsulinism prioritized research agenda: a patient-driven international collaborative research network.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1549310

By:

Pasquini, Tai L. S.;
Banerjee, Indraneel;
Christesen, Henrik Thybo;
Conwell, Louise S.;
Dastamani, Antonia;
De Leon, Diva D.;
Flanagan, Sarah E.;
Gillis, David;
Kalish, Jennifer M.;
Lord, Katherine;
Mesfin, Mahlet;
Schmitt, Jennifer;
Senniappan, Senthil;
Stanley, Charles A.;
Thornton, Paul S.;
Zangen, David;
Raskin, Julie

Publication type:

Article

Variation in Glycemic Outcomes in Focal Forms of Congenital Hyperinsulinism—The UK Perspective.

Published in:

Journal of the Endocrine Society, 2022, v. 6, n. 6, p. 1, doi. 10.1210/jendso/bvac033

By:

Dastamani, Antonia;
Yau, Daphne;
Gilbert, Clare;
Morgan, Kate;
Coppi, Paolo De;
Craigie, Ross J;
Bomanji, Jamshed;
Biassoni, Lorenzo;
Sajjan, Rakesh;
Flanagan, Sarah E;
Houghton, Jayne A L;
Senniappan, Senthil;
Didi, Mohammed;
Dunne, Mark J;
Banerjee, Indraneel;
Shah, Pratik

Publication type:

Article

A Rare Case of Heterozygous Gain of Function Thyrotropin Receptor Mutation Associated with Development of Thyroid Follicular Carcinoma.

Published in:

Case Reports in Genetics, 2018, p. 1, doi. 10.1155/2018/1381730

By:

Blackburn, James;
Giri, Dinesh;
Ciolka, Barbara;
Gossan, Nicole;
Didi, Mohammad;
Kokai, George;
Waghorn, Alison;
Jones, Matthew;
Senniappan, Senthil

Publication type:

Article

Novel Splicing Mutation in B3GAT3 Associated with Short Stature, GH Deficiency, Hypoglycaemia, Developmental Delay, and Multiple Congenital Anomalies.

Published in:

2017

By:

Bloor, Samuel;
Giri, Dinesh;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Case Study

Insulin oedema in a child with newly diagnosed diabetes mellitus.

Published in:

European Journal of Pediatrics, 2014, v. 173, n. 5, p. 685, doi. 10.1007/s00431-013-2045-0

By:

Aravamudhan, Avinash;
Gardner, Chris;
Smith, Claire;
Senniappan, Senthil

Publication type:

Article

Biochemical studies in patients with hyperinsulinaemic hypoglycaemia.

Published in:

European Journal of Pediatrics, 2013, v. 172, n. 11, p. 1435, doi. 10.1007/s00431-013-2053-0

By:

Al-Otaibi, Hessah;
Senniappan, Senthil;
Alam, Syeda;
Hussain, Khalid

Publication type:

Article

The effect of socioeconomic deprivation on efficacy of continuous subcutaneous insulin infusion: a retrospective paediatric case-controlled survey.

Published in:

2012

By:

Senniappan S;
Hine P;
Tang W;
Campbell J;
Bone M;
Sankar V;
Robinson M;
Smith C;
Cooper C;
Amin R;
North West England Paediatric Diabetes Network;
Senniappan, Senthil;
Hine, Paul;
Tang, Wing;
Campbell, Judith;
Bone, Mark;
Sankar, Vengudi;
Robinson, Mark;
Smith, Claire;
Cooper, Chris

Publication type:

journal article

Semaglutide, a Long-Acting GLP-1 Analogue, for the Management of Early-Onset Obesity due to MC4R Defect: A Case Report.

Published in:

Hormone Research in Paediatrics, 2025, v. 98, n. 2, p. 148, doi. 10.1159/000537921

By:

Gokul, Pon Ramya;
Apperley, Louise;
Parkinson, Jennifer;
Clark, Kate;
Lund, Kim;
Owens, Megan;
Senniappan, Senthil

Publication type:

Article

Improvements in Glucose Regulation in Children and Young People with Cystic Fibrosis-Related Diabetes following Initiation of Elexacaftor/Tezacaftor/Ivacaftor.

Published in:

Hormone Research in Paediatrics, 2024, v. 97, n. 1, p. 94, doi. 10.1159/000530571

By:

Park, Julie;
Walsh, Anna;
Kerr, Sue;
Woodland, Clare;
Southward, Suzanne;
Deakin, Mark;
Senniappan, Senthil;
Thursfield, Rebecca

Publication type:

Article

Burosumab Therapy in a Paediatric Patient with McCune-Albright Syndrome: A Case Report.

Published in:

Hormone Research in Paediatrics, 2023, v. 96, n. 3, p. 341, doi. 10.1159/000527129

By:

Apperley, Louise J.;
Senniappan, Senthil

Publication type:

Article

Heterozygous CDC73 mutation causing hyperparathyroidism in children and adolescents: a report of 2 cases.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2022, v. 35, n. 12, p. 1547, doi. 10.1515/jpem-2022-0299

By:

Blackburn, James;
Mulvey, Ian;
Nadar, Ruchi;
Dias, Renuka P.;
Saraff, Vrinda;
Senniappan, Senthil

Publication type:

Article

Congenital hyperinsulinism: recent updates on molecular mechanisms, diagnosis and management.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2022, v. 35, n. 3, p. 279, doi. 10.1515/jpem-2021-0369

By:

Giri, Dinesh;
Hawton, Katherine;
Senniappan, Senthil

Publication type:

Article

Liraglutide combined with intense lifestyle modification in the management of obesity in adolescents.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2021, v. 34, n. 5, p. 613, doi. 10.1515/jpem-2020-0714

By:

Apperley, Louise J.;
Gait, Lucy;
Erlandson-Parry, Karen;
Laing, Peter;
Senniappan, Senthil

Publication type:

Article

Isolated premature menarche in two siblings with Neurofibromatosis type 1.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2020, v. 33, n. 6, p. 813, doi. 10.1515/jpem-2019-0494

By:

Blackburn, James;
Didi, Mohammed;
Avula, Shivaram;
Senniappan, Senthil

Publication type:

Article

Hyperinsulinism hyperammonaemia (HI/HA) syndrome due to GLUD1 mutation: phenotypic variations ranging from late presentation to spontaneous resolution.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2020, v. 33, n. 3, p. 675, doi. 10.1515/jpem-2019-0416

By:

Brandt, Agnieszka;
Agarwal, Neha;
Giri, Dinesh;
Yung, Zoe;
Didi, Mohammad;
Senniappan, Senthil

Publication type:

Article

A rare case of congenital hyperinsulinism (CHI) due to dual genetic aetiology involving HNF4A and ABCC8.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2019, v. 32, n. 3, p. 301, doi. 10.1515/jpem-2018-0389

By:

Apperley, Louise;
Giri, Dinesh;
Houghton, Jayne A.L.;
Flanagan, Sarah E.;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Article

Successful transition to sulfonylurea therapy in two Iraqi siblings with neonatal diabetes mellitus and iDEND syndrome due to ABCC8 mutation.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2016, v. 29, n. 12, p. 1403, doi. 10.1515/jpem-2016-0149

By:

Ozsu, Elif;
Giri, Dinesh;
Karabulut, Gulcan Seymen;
Senniappan, Senthil

Publication type:

Article

Idiopathic postprandial hyperinsulinaemic hypoglycaemia.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2016, v. 29, n. 8, p. 915, doi. 10.1515/jpem-2016-0043

By:

Güemes, Maria;
Melikyan, Maria;
Senniappan, Senthil;
Hussain, Khalid

Publication type:

Article

Protein-induced hyperinsulinaemic hypoglycaemia due to a homozygous HADH mutation in three siblings of a Saudi family.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2015, v. 28, n. 9/10, p. 1073, doi. 10.1515/jpem-2015-0033

By:

Babiker, Omer;
Flanagan, Sarah E.;
Ellard, Sian;
Al Girim, Hesham;
Hussain, Khalid;
Senniappan, Senthil

Publication type:

Article

Sirolimus therapy in a patient with severe hyperinsulinaemic hypoglycaemia due to a compound heterozygous ABCC8 gene mutation.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2015, v. 28, n. 5/6, p. 695, doi. 10.1515/jpem-2014-0371

By:

Shah, Pratik;
Arya, Ved Bhushan;
Flanagan, Sarah E.;
Morgan, Kate;
Ellard, Sian;
Senniappan, Senthil;
Hussain, Khalid

Publication type:

Article

The heterogeneity of hyperinsulinaemic hypoglycaemia in 19 patients with Beckwith-Wiedemann syndrome due to KvDMR1 hypomethylation.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2015, v. 28, n. 1/2, p. 83, doi. 10.1515/jpem-2013-0390

By:

Senniappan, Senthil;
Ismail, Dunia;
Shipster, Caroleen;
Beesley, Clare;
Hussain, Khalid

Publication type:

Article

Chromosome 6q24 transient neonatal diabetes mellitus and protein sensitive hyperinsulinaemic hypoglycaemia.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2014, v. 27, n. 11/12, p. 1065, doi. 10.1515/jpem-2014-0031

By:

Kalaivanan, Prabhakaran;
Arya, Ved Bhushan;
Shah, Pratik;
Datta, Vipan;
Flanagan, Sarah E.;
Mackay, Deborah J.G.;
Ellard, Sian;
Senniappan, Senthil;
Hussain, Khalid

Publication type:

Article

Pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus (PHID) syndrome is associated with severe chronic inflammation and cardiomyopathy, and represents a new monogenic autoinflammatory syndrome.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2013, v. 26, n. 9/10, p. 877, doi. 10.1515/jpem-2013-0062

By:

Senniappan, Senthil;
Hughes, Marina;
Shah, Pratik;
Shah, Vanita;
Kaski, Juan Pablo;
Brogan, Paul;
Hussain, Khalid

Publication type:

Article

Morphoproteomics and biomedical analytics coincide with clinical outcomes in supporting a constant but variable role for the mTOR pathway in the biology of congenital hyperinsulinism of infancy.

Published in:

2017

By:

Brown, Robert E.;
Senniappan, Senthil;
Hussain, Khalid;
McGuire, Mary F.

Publication type:

Letter

Hyperinsulinaemic hypoglycaemia: genetic mechanisms, diagnosis and management.

Published in:

Journal of Inherited Metabolic Disease, 2012, v. 35, n. 4, p. 589, doi. 10.1007/s10545-011-9441-2

By:

Senniappan, Senthil;
Shanti, Balasubramaniam;
James, Chela;
Hussain, Khalid

Publication type:

Article

Standardised practices in the networked management of congenital hyperinsulinism: a UK national collaborative consensus.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1231043

By:

Shaikh, M. Guftar;
Lucas-Herald, Angela K.;
Dastamani, Antonia;
Estebanez, Maria Salomon;
Senniappan, Senthil;
Abid, Noina;
Ahmad, Sumera;
Alexander, Sophie;
Avatapalle, Bindu;
Awan, Neelam;
Blair, Hester;
Boyle, Roisin;
Chesover, Alexander;
Cochrane, Barbara;
Craigie, Ross;
Cunjamalay, Annaruby;
Dearman, Sarah;
De Coppi, Paolo;
Erlandson-Parry, Karen;
Flanagan, Sarah E.

Publication type:

Article

Clinical and histological heterogeneity of congenital hyperinsulinism due to paternally inherited heterozygous ABCC8/KCNJ11 mutations.

Published in:

European Journal of Endocrinology, 2014, v. 171, n. 6, p. 685, doi. 10.1530/EJE-14-0353

By:

Arya, Ved Bhushan;
Guemes, Maria;
Nessa, Azizun;
Alam, Syeda;
Shah, Pratik;
Gilbert, Clare;
Senniappan, Senthil;
Flanagan, Sarah E.;
Ellard, Sian;
Hussain, Khalid

Publication type:

Article

Posaconazole-Induced Hypertension Masquerading as Congenital Adrenal Hyperplasia in a Child with Cystic Fibrosis.

Published in:

Case Reports in Medicine, 2020, p. 1, doi. 10.1155/2020/8153012

By:

Agarwal, Neha;
Apperley, Louise;
Taylor, Norman F.;
Taylor, David R.;
Ghataore, Lea;
Rumsby, Ellen;
Treslove, Catherine;
Holt, Richard;
Thursfield, Rebecca;
Senniappan, Senthil

Publication type:

Article

Heterozygous Insulin Receptor (INSR) Mutation Associated with Neonatal Hyperinsulinemic Hypoglycaemia and Familial Diabetes Mellitus: Case Series.

Published in:

Journal of Clinical Research in Pediatric Endocrinology, 2020, v. 12, n. 4, p. 420, doi. 10.4274/jcrpe.galenos.2019.2019.0106

By:

Sethi, Aashish;
Foulds, Nicola;
Ehtisham, Sarah;
Ahmed, Syed Haris;
Houghton, Jayne;
Colclough, Kevin;
Didi, Mohammed;
Flanagan, Sarah E.;
Senniappan, Senthil

Publication type:

Article

Fluoxetine-Induced Hypoglycaemia in a Patient with Congenital Hyperinsulinism on Lanreotide Therapy.

Published in:

Journal of Clinical Research in Pediatric Endocrinology, 2016, v. 8, n. 3, p. 347, doi. 10.4274/jcrpe.2818

By:

Giri, Dinesh;
Price, Victoria;
Zoe Yung;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Article

Case 2: Fractures in under-6-month-old exclusively breast-fed infants born to immigrant parents: nonaccidental injury? (case presentation). Diagnosis: Pathological fractures secondary to vitamin D deficiency rickets in under-6-months-old, exclusively breast-fed infants, born to immigrant parents.

Published in:

2008

By:

Senniappan S;
Elazabi A;
Doughty I;
Mughal MZ;
Senniappan, Senthil;
Elazabi, Ahmed;
Doughty, Ian;
Mughal, M Zulf

Publication type:

journal article

Case 2: Fractures in under-6-month-old exclusively breast-fed infants born to immigrant parents: nonaccidental injury? (Case Presentation).

Published in:

Acta Paediatrica, 2008, v. 97, n. 7, p. 836, doi. 10.1111/j.1651-2227.2008.00790.x

By:

Senniappan, Senthil;
Elazabi, Ahmed;
Doughty, Ian;
Mughal, M. Zulf

Publication type:

Article

Case 2: Fractures in under-6-month-old exclusively breast-fed infants born to immigrant parents: nonaccidental injury? (Discussion and Diagnosis).

Published in:

Acta Paediatrica, 2008, v. 97, n. 7, p. 992, doi. 10.1111/j.1651-2227.2008.00799.x

By:

Senniappan, Senthil;
Elazabi, Ahmed;
Doughty, Ian;
Mughal, M. Zulf

Publication type:

Article

Idiopathic intracranial hypertension in children with obesity.

Published in:

Acta Paediatrica, 2022, v. 111, n. 7, p. 1420, doi. 10.1111/apa.16343

By:

Apperley, Louise;
Kumar, Ram;
Senniappan, Senthil

Publication type:

Article

Neonatal Hypoglycemia.

Published in:

Indian Journal of Pediatrics, 2014, v. 81, n. 1, p. 58, doi. 10.1007/s12098-013-1135-3

By:

Arya, Ved;
Senniappan, Senthil;
Guemes, Maria;
Hussain, Khalid

Publication type:

Article

On X-Linked Hypophosphatemia at the European Society of Pediatric Endocrinology Meeting, Vienna, Austria; September 19-21, 2019.

Published in:

Ibnosina Journal of Medicine & Biomedical Sciences, 2020, v. 12, n. 1, p. 68, doi. 10.4103/ijmbs.ijmbs_3_20

By:

Alsaffar, Hussain;
Senniappan, Senthil;
Linglart, Agnès

Publication type:

Article

Mode of clinical presentation and delayed diagnosis of Turner syndrome: a single Centre UK study.

Published in:

International Journal of Pediatric Endocrinology, 2018, v. 2018, n. 1, p. N.PAG, doi. 10.1186/s13633-018-0058-1

By:

Apperley, Louise;
Das, Urmi;
Ramakrishnan, Renuka;
Dharmaraj, Poonam;
Blair, Jo;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Article

Continuous Flash Glucose Monitoring in children with Congenital Hyperinsulinism; first report on accuracy and patient experience.

Published in:

International Journal of Pediatric Endocrinology, 2018, v. 2018, p. 1, doi. 10.1186/s13633-018-0057-2

By:

Alsaffar, Hussain;
Turner, Lucy;
Yung, Zoe;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Article

Novel compound heterozygous ASXL3 mutation causing Bainbridge-ropers like syndrome and primary IGF1 deficiency.

Published in:

International Journal of Pediatric Endocrinology, 2017, v. 2017, p. 1, doi. 10.1186/s13633-017-0047-9

By:

Giri, Dinesh;
Rigden, Daniel;
Didi, Mohammed;
Peak, Matthew;
McNamara, Paul;
Senniappan, Senthil

Publication type:

Article

Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control.

Published in:

BMC Research Notes, 2017, v. 10, p. 1, doi. 10.1186/s13104-017-2794-3

By:

Giri, Dinesh;
Pintus, Dona;
Burnside, Girvan;
Ghatak, Atrayee;
Mehta, Fulya;
Paul, Princy;
Senniappan, Senthil

Publication type:

Article

Research Letters.

Published in:

2018

By:

Kumawat, Devesh;
Chandra, Parijat;
Tewari, Ruchir;
Naaraayan, Sridevi A.;
Varadharajan, Poovazhagi;
Dhakshayani, Raghavan Velayutham;
Chandramohan, Rema;
Senniappan, Senthil

Publication type:

Case Study

Research Letters.

Published in:

Indian Pediatrics, 2018, v. 55, n. 2, p. 165, doi. 10.1007/s13312-018-1253-0

By:

Alonso-Ojembarrena, Almudena;
Segado-Arenas, Antonio;
Benavente-Fernández, Isabel;
Lubián-López, Simón Pedro;
Trakarnvanich, Thananda;
Sethasine, Supatsri;
Trisuwanwat, Charnarong;
Insawang, Methavee;
Patil, Prashant;
Giri, Dinesh;
Didi, Mohammed;
Senniappan, Senthil

Publication type:

Article

Evaluation of the etiology and outcome of hypoglycemia in young children - A challenging task.

Published in:

Journal of Pediatric Endocrinology & Diabetes, 2023, v. 3, n. 3, p. 95, doi. 10.25259/JPED_7_2024

By:

Senniappan, Senthil;
Ramakrishnan, Anand

Publication type:

Article

Genotype and phenotype correlations in Iranian patients with hyperinsulinaemic hypoglycaemia.

Published in:

BMC Research Notes, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13104-015-1319-1

By:

Senniappan, Senthil;
Sadeghizadeh, Atefeh;
Flanagan, Sarah E.;
Ellard, Sian;
Hashemipour, Mahin;
Hosseinzadeh, Majid;
Salehi, Mansour;
Hussain, Khalid

Publication type:

Article

Congenital hyperinsulinism: diagnostic and management challenges in a developing country -- case report.

Published in:

2017

By:

John, Cheri Mathews;
Agarwal, Prakash;
Govindarajulu, Suriyakumar;
Sundaram, Sandhya;
Senniappan, Senthil

Publication type:

Case Study

A rare association of central hypothyroidism and adrenal insufficiency in a boy with Williams-Beuren syndrome.

Published in:

2017

By:

Dayal, Devi;
Giri, Dinesh;
Senniappan, Senthil

Publication type:

Case Study

An eHealth Framework for Managing Pediatric Growth Disorders and Growth Hormone Therapy.

Published in:

2021

By:

Dimitri, Paul;
Fernandez-Luque, Luis;
Banerjee, Indraneel;
Bergadá, Ignacio;
Calliari, Luis Eduardo;
Dahlgren, Jovanna;
Arriba, Antonio de;
Lapatto, Risto;
Reinehr, Thomas;
Senniappan, Senthil;
Thomas-Teinturier, Cécile;
Tsai, Meng-Che;
Zaini, Azriyanti Anuar;
Bagha, Merat;
Koledova, Ekaterina;
de Arriba, Antonio;
Anuar Zaini, Azriyanti

Publication type:

journal article

Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 22, p. 4315, doi. 10.1093/hmg/ddx318

By:

Giri, Dinesh;
Vignola, Maria Lillina;
Gualtieri, Angelica;
Scagliotti, Valeria;
McNamara, Paul;
Peak, Matthew;
Didi, Mohammed;
Gaston-Massuet, Carles;
Senniappan, Senthil

Publication type:

Article

The hypoglycaemia error grid: A UK-wide consensus on CGM accuracy assessment in hyperinsulinism.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.1016072

By:

Worth, Chris;
Dunne, Mark J.;
Salomon-Estebanez, Maria;
Harper, Simon;
Nutter, Paul W.;
Dastamani, Antonia;
Senniappan, Senthil;
Banerjee, Indraneel

Publication type:

Article

Liraglutide Treatment Improves Glycaemic Dysregulation, Body Composition, Cardiometabolic Variables and Uncontrolled Eating Behaviour in Adolescents with Severe Obesity.

Published in:

Journal of Clinical Research in Pediatric Endocrinology, 2025, v. 17, n. 1, p. 68, doi. 10.4274/jcrpe.galenos.2024.2023-10-10

By:

Apperley, Louise;
Parkinson, Jennifer;
Senniappan, Senthil

Publication type:

Article