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Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24442-9
By:
- Van Thillo, Quentin;
- De Bie, Jolien;
- Seneviratne, Janith A.;
- Demeyer, Sofie;
- Omari, Sofia;
- Balachandran, Anushree;
- Zhai, Vicki;
- Tam, Wai L.;
- Sweron, Bram;
- Geerdens, Ellen;
- Gielen, Olga;
- Provost, Sarah;
- Segers, Heidi;
- Boeckx, Nancy;
- Marshall, Glenn M.;
- Cheung, Belamy B.;
- Isobe, Kiyotaka;
- Kato, Itaru;
- Takita, Junko;
- Amos, Timothy G.
Publication type:
Article
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22143-x
By:
- Nagy, Zsuzsanna;
- Seneviratne, Janith A.;
- Kanikevich, Maxwell;
- Chang, William;
- Mayoh, Chelsea;
- Venkat, Pooja;
- Du, Yanhua;
- Jiang, Cizhong;
- Salib, Alice;
- Koach, Jessica;
- Carter, Daniel R.;
- Mittra, Rituparna;
- Liu, Tao;
- Parker, Michael W.;
- Cheung, Belamy B.;
- Marshall, Glenn M.
Publication type:
Article
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.
Published in:
International Journal of Cancer, 2023, v. 152, n. 7, p. 1399, doi. 10.1002/ijc.34349
By:
- Seneviratne, Janith A.;
- Carter, Daniel R.;
- Mittra, Rituparna;
- Gifford, Andrew;
- Kim, Patrick Y.;
- Luo, Jie‐Si;
- Mayoh, Chelsea;
- Salib, Alice;
- Rahmanto, Aldwin S.;
- Murray, Jayne;
- Cheng, Ngan C.;
- Nagy, Zsuzsanna;
- Wang, Qian;
- Kleynhans, Ane;
- Tan, Owen;
- Sutton, Selina K.;
- Xue, Chengyuan;
- Chung, Sylvia A.;
- Zhang, Yizhuo;
- Sun, Chengtao
Publication type:
Article
Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06899-8
By:
- Cheung, Belamy B.;
- Mittra, Ritu;
- Murray, Jayne;
- Wang, Qian;
- Seneviratne, Janith A.;
- Raipuria, Mukesh;
- Wong, Iris Poh Ling;
- Restuccia, David;
- Gifford, Andrew;
- Salib, Alice;
- Sutton, Selina;
- Huang, Libby;
- Ferdowsi, Parisa Vahidi;
- Tsang, Joanna;
- Sekyere, Eric;
- Mayoh, Chelsea;
- Luo, Lin;
- Brown, Darren L.;
- Stow, Jennifer L.;
- Zhu, Shizhen
Publication type:
Article
The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.863329
By:
- Xiao, Lin;
- Karsa, Mawar;
- Ronca, Emma;
- Bongers, Angelika;
- Kosciolek, Angelika;
- El-Ayoubi, Ali;
- Revalde, Jezrael L.;
- Seneviratne, Janith A.;
- Cheung, Belamy B.;
- Cheung, Laurence C.;
- Kotecha, Rishi S.;
- Newbold, Andrea;
- Bjelosevic, Stefan;
- Arndt, Greg M.;
- Lock, Richard B.;
- Johnstone, Ricky W.;
- Gudkov, Andrei V.;
- Gurova, Katerina V.;
- Haber, Michelle;
- Norris, Murray D.
Publication type:
Article
A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin.
Published in:
Epigenetics & Chromatin, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13072-024-00527-9
By:
- Seneviratne, Janith A.;
- Ho, William W. H.;
- Glancy, Eleanor;
- Eckersley-Maslin, Melanie A.
Publication type:
Article
Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 21, p. 15571, doi. 10.3390/ijms242115571
By:
- Zhai, Lei;
- Balachandran, Anushree;
- Larkin, Rebecca;
- Seneviratne, Janith A.;
- Chung, Sylvia A.;
- Lalwani, Amit;
- Tsubota, Shoma;
- Beck, Dominik;
- Kadomatsu, Kenji;
- Beckers, Anneleen;
- Durink, Kaat;
- De Preter, Katleen;
- Speleman, Frank;
- Haber, Michelle;
- Norris, Murray D.;
- Swarbrick, Alexander;
- Cheung, Belamy B.;
- Marshall, Glenn M.;
- Carter, Daniel R.
Publication type:
Article

Found: 7

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.

An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability.

Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.

Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis.

The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.

A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin.

Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.