Works by Seneca, Nicholas

Results: 22

Kinetic Modeling of the Tau PET Tracer 18F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.

Published in:

Journal of Nuclear Medicine, 2017, v. 58, n. 7, p. 1124, doi. 10.2967/jnumed.116.182881

By:

Barret, Olivier;
Alagille, David;
Sanabria, Sandra;
Comley, Robert A.;
Weimer, Robby M.;
Borroni, Edilio;
Mintun, Mark;
Seneca, Nicholas;
Papin, Caroline;
Morley, Thomas;
Marek, Ken;
Seibyl, John P.;
Tamagnan, Gilles D.;
Jennings, Danna

Publication type:

Article

P-Glycoprotein Function at the Blood--Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide.

Published in:

Journal of Nuclear Medicine, 2010, v. 51, n. 4, p. 559, doi. 10.2967/jnumed.109.070151

By:

Kreisl, William C.;
Jeih-San Liow;
Kimura, Nobuyo;
Seneca, Nicholas;
Zoghbi, Sami S.;
Morse, Cheryl L.;
Herscovitch, Peter;
Pike, Victor W.;
Innis, Robert B.

Publication type:

Article

Human Brain Imaging and Radiation Dosimetry of 11C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein.

Published in:

Journal of Nuclear Medicine, 2009, v. 50, n. 5, p. 807, doi. 10.2967/jnumed.108.058453

By:

Seneca, Nicholas;
Zoghbi, Sami S.;
Liow, Jeih-San;
Kreisl, William;
Herscovitch, Peter;
Jenko, Kimberly;
Gladding, Robert L.;
Taku, Andrew;
Pike, Victor W.;
Innis, Robert B.

Publication type:

Article

P-Glycoprotein Function at the Blood--Brain Barrier Imaged Using 11C-N-Desmethyl- Loperamide in Monkeys.

Published in:

Journal of Nuclear Medicine, 2009, v. 50, n. 1, p. 108, doi. 10.2967/jnumed.108.056226

By:

Jeih-San Liow;
Kreisl, William;
Zoghbi, Sami S.;
Lazarova, Neva;
Seneca, Nicholas;
Gladding, Robert L.;
Taku, Andrew;
Herscovitch, Peter;
Pike, Victor W.;
Innis, Robert B.

Publication type:

Article

Dopamine β-hydroxylase-deficient mice have normal densities of D2 dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding.

Published in:

Synapse, 2010, v. 64, n. 9, p. 699, doi. 10.1002/syn.20781

By:

Skinbjerg, Mette;
Seneca, Nicholas;
Liow, Jeih-San;
Hong, Jinsoo;
Weinshenker, David;
Pike, Victor W.;
Halldin, Christer;
Sibley, David R.;
Innis, Robert B.

Publication type:

Article

Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA.

Published in:

Synapse, 2008, v. 62, n. 10, p. 756, doi. 10.1002/syn.20549

By:

Seneca, Nicholas;
Zoghbi, Sami S.;
Skinbjerg, Mette;
Liow, Jeih-San;
Hong, Jinsoo;
Sibley, David R.;
Pike, Victor W.;
Halldin, Christer;
Innis, Robert B.

Publication type:

Article

Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: A dopamine agonist radioligand.

Published in:

Synapse, 2008, v. 62, n. 9, p. 700, doi. 10.1002/syn.20544

By:

Seneca, Nicholas;
Skinbjerg, Mette;
Zoghbi, Sami S.;
Liow, Jeih-San;
Gladding, Robert L.;
Hong, Jinsoo;
Kannan, Pavitra;
Tuan, Edward;
Sibley, David R.;
Halldin, Christer;
Pike, Victor W.;
Innis, Robert B.

Publication type:

Article

Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.

Published in:

Synapse, 2006, v. 59, n. 5, p. 260, doi. 10.1002/syn.20238

By:

Seneca, Nicholas;
Finnema, Sjoerd J.;
Farde, Lars;
Gulyás, Balázs;
Wikström, Håkan V.;
Halldin, Christer;
Innis, Robert B.

Publication type:

Article

Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2017, v. 44, n. 3, p. 382, doi. 10.1007/s00259-016-3510-6

By:

Sturm, Stefan;
Forsberg, Anton;
Nave, Stephane;
Stenkrona, Per;
Seneca, Nicholas;
Varrone, Andrea;
Comley, Robert;
Fazio, Patrik;
Jamois, Candice;
Nakao, Ryuji;
Ejduk, Zbigniew;
Al-Tawil, Nabil;
Akenine, Ulrika;
Halldin, Christer;
Andreasen, Niels;
Ricci, Benedicte

Publication type:

Article

C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 7, p. 1081, doi. 10.1007/s00259-015-3043-4

By:

Park, Eunkyung;
Gallezot, Jean-Dominique;
Delgadillo, Aracely;
Liu, Shuang;
Planeta, Beata;
Lin, Shu-Fei;
O'Connor, Kevin;
Lim, Keunpoong;
Lee, Jae-Yun;
Chastre, Anne;
Chen, Ming-Kai;
Seneca, Nicholas;
Leppert, David;
Huang, Yiyun;
Carson, Richard;
Pelletier, Daniel

Publication type:

Article

Correlation of F-FDG PET/CT assessments with disease activity and markers of inflammation in patients with early rheumatoid arthritis following the initiation of combination therapy with triple oral antirheumatic drugs.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2013, v. 40, n. 3, p. 403, doi. 10.1007/s00259-012-2282-x

By:

Roivainen, Anne;
Hautaniemi, Sannamari;
Möttönen, Timo;
Nuutila, Pirjo;
Oikonen, Vesa;
Parkkola, Riitta;
Pricop, Luminita;
Ress, Rudyard;
Seneca, Nicholas;
Seppänen, Marko;
Yli-Kerttula, Timo

Publication type:

Article

Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain.

Published in:

Annals of Clinical & Translational Neurology, 2014, v. 1, n. 9, p. 659, doi. 10.1002/acn3.94

By:

Anthony, Daniel C.;
Dickens, Alex M.;
Seneca, Nicholas;
Couch, Yvonne;
Campbell, Sandra;
Checa, Begona;
Kersemans, Veerle;
Warren, Edward A.;
Tredwell, Matthew;
Sibson, Nicola R.;
Gouverneur, Veronique;
Leppert, David

Publication type:

Article

Neuroimaging and Physiological Evidence for Involvement of Glutamatergic Transmission in Regulation of the Striatal Dopaminergic System.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 6, p. 1887, doi. 10.1523/JNEUROSCI.2559-08.2009

By:

Tokunaga, Masaki;
Seneca, Nicholas;
Ryong-Moon Shin;
Maeda, Jun;
Obayashi, Shigeru;
Okauchi, Takashi;
Nagai, Yuji;
Ming-Rong Zhang;
Nakao, Ryuji;
Ito, Hiroshi;
Innis, Robert B.;
Halldin, Christer;
Suzuki, Kazutoshi;
Higuchi, Makoto;
Suhara, Tetsuya

Publication type:

Article

Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 8, p. 1499, doi. 10.1007/s00259-010-1411-7

By:

Terry, Garth E.;
Hirvonen, Jussi;
Liow, Jeih-San;
Seneca, Nicholas;
Tauscher, Johannes T.;
Schaus, John M.;
Phebus, Lee;
Felder, Christian C.;
Morse, Cheryl L.;
Pike, Victor W.;
Halldin, Christer;
Innis, Robert B.

Publication type:

Article

Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D2 receptors using [123I]epidepride SPET.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2004, v. 31, n. 5, p. 644, doi. 10.1007/s00259-003-1431-7

By:

Fujita, Masahiro;
Varrone, Andrea;
Kim, Kyeong Min;
Watabe, Hiroshi;
Zoghbi, Sami S.;
Seneca, Nicholas;
Tipre, Dnyanesh;
Seibyl, John P.;
Innis, Robert B.;
Iida, Hidehiro

Publication type:

Article

Quantification of nicotinic acetylcholine receptors in human brain using [123I ]5-I-A-85380 SPET.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2003, v. 30, n. 12, p. 1620, doi. 10.1007/s00259-003-1320-0

By:

Fujita, Masahiro;
Ichise, Masanori;
van Dyck, Christopher H.;
Zoghbi, Sami S.;
Tamagnan, Gilles;
Mukhin, Alexey G.;
Bozkurt, Ali;
Seneca, Nicholas;
Tipre, Dnyanesh;
DeNucci, Christopher C.;
Iida, Hidehiro;
Vaupel, D. Bruce;
Horti, Andrew G.;
Koren, Andrei O.;
Kimes, Alane S.;
London, Edythe D.;
Seibyl, John P.;
Baldwin, Ronald M.;
Innis, Robert B.

Publication type:

Article

Changes in Human In vivo Serotonin and Dopamine Transporter Availabilities during Chronic Antidepressant Administration.

Published in:

Neuropsychopharmacology, 2003, v. 28, n. 2, p. 413, doi. 10.1038/sj.npp.1300036

By:

Kugaya, Akira;
Seneca, Nicholas M.;
Snyder, Peter J.;
Williams, Stephen A.;
Malison, Robert T.;
Baldwin, Ronald M.;
Seibyl, John P.;
Innis, Robert B.

Publication type:

Article

API generation program: Active immunotherapy CAD106 slows amyloid deposition in cognitively unimpaired APOE4 homozygotes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051287

By:

Riviere, Marie‐Emmanuelle;
Turner, Raymond Scott;
Sui, Yihan;
Laurent, Nathalie;
Langbaum, Jessica B.;
Cazorla, Pilar;
Ricart, Javier;
Seneca, Nicholas;
Caputo, Angelika;
Reiman, Eric M.;
Tariot, Pierre N.;
Graf, Ana

Publication type:

Article

The API Generation program: Biomarker phenotyping of cognitively unimpaired participants screened in Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041143

By:

Rouzade‐Dominguez, Marie‐Laure;
Riviere, Marie‐Emmanuelle;
Borowsky, Beth;
Liu, Fonda;
Cazorla, Pilar;
Quinn, Matt;
Seneca, Nicholas;
Neumann, Ulf;
Eichenlaub, Udo;
Chien, Yuchen;
Viglietta, Vissia;
Reiman, Eric M.;
Sui, Yihan;
Caputo, Angelika;
Graf, Ana

Publication type:

Article

The API Generation program: Umibecestat treatment and discontinuation effects on hippocampal and whole brain volumes in the overall population and amyloid‐negative APOE4 homozygotes: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041142

By:

Reiman, Eric M.;
Tariot, Pierre N.;
Borowsky, Beth;
Liu, Fonda;
Riviere, Marie‐Emmanuelle;
Rouzade‐Dominguez, Marie‐Laure;
Cazorla, Pilar;
Quinn, Matt;
Ricart, Javier;
Langbaum, Jessica B.;
Viglietta, Vissia;
Sui, Yihan;
Caputo, Angelika;
Graf, Ana;
Seneca, Nicholas;
Neumann, Ulf;
Eichenlaub, Udo;
Chien, Yuchen;
Arkuszewski, Michal;
Piccard, Hernan

Publication type:

Article

Occupancy of dopamine D and D and serotonin 5-HT receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography.

Published in:

Psychopharmacology, 2011, v. 218, n. 3, p. 579, doi. 10.1007/s00213-011-2343-z

By:

Seneca, Nicholas;
Finnema, Sjoerd;
Laszlovszky, István;
Kiss, Béla;
Horváth, Attila;
Pásztor, Gabriella;
Kapás, Margó;
Gyertyán, István;
Farkas, Sándor;
Innis, Robert;
Halldin, Christer;
Gulyás, Balázs

Publication type:

Article

Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using ( S, S)-[18F]FMeNER-D2.

Published in:

Psychopharmacology, 2006, v. 188, n. 1, p. 119, doi. 10.1007/s00213-006-0483-3

By:

Seneca, Nicholas;
Gulyás, Balázs;
Varrone, Andrea;
Schou, Magnus;
Airaksinen, Anu;
Tauscher, Johannes;
Vandenhende, Francois;
Kielbasa, William;
Farde, Lars;
Innis, Robert B.;
Halldin, Christer

Publication type:

Article

Works by Seneca, Nicholas

Kinetic Modeling of the Tau PET Tracer <sup>18</sup>F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.

P-Glycoprotein Function at the Blood--Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer <sup>11</sup>C-N-Desmethyl-Loperamide.

Human Brain Imaging and Radiation Dosimetry of <sup>11</sup>C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein.

P-Glycoprotein Function at the Blood--Brain Barrier Imaged Using <sup>11</sup>C-N-Desmethyl- Loperamide in Monkeys.

Dopamine β-hydroxylase-deficient mice have normal densities of D<sub>2</sub> dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding.

Occupancy of dopamine D<sub>2/3</sub> receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [<sup>11</sup>C]MNPA.

Kinetic brain analysis and whole-body imaging in monkey of [<sup>11</sup>C]MNPA: A dopamine agonist radioligand.

Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [<sup>11</sup>C]MNPA and antagonist [<sup>11</sup>C]raclopride.

Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.

C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas.

Correlation of F-FDG PET/CT assessments with disease activity and markers of inflammation in patients with early rheumatoid arthritis following the initiation of combination therapy with triple oral antirheumatic drugs.

Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain.

Neuroimaging and Physiological Evidence for Involvement of Glutamatergic Transmission in Regulation of the Striatal Dopaminergic System.

Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB<sub>1</sub> receptors using positron emission tomography.

Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D<sub>2</sub> receptors using [<sup>123</sup>I]epidepride SPET.

Quantification of nicotinic acetylcholine receptors in human brain using [<sup>123</sup>I ]5-I-A-85380 SPET.

Changes in Human In vivo Serotonin and Dopamine Transporter Availabilities during Chronic Antidepressant Administration.

API generation program: Active immunotherapy CAD106 slows amyloid deposition in cognitively unimpaired APOE4 homozygotes.

The API Generation program: Biomarker phenotyping of cognitively unimpaired participants screened in Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up

Occupancy of dopamine D and D and serotonin 5-HT receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography.

Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using ( S, S)-[<sup>18</sup>F]FMeNER-D<sub>2</sub>.