Works by Selth, Luke A.

Results: 37

IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor.

Published in:

2016

By:

Carter, Sarah Louise;
Centenera, Margaret Mary;
Tilley, Wayne Desmond;
Selth, Luke Ashton;
Butler, Lisa Maree;
Carter, Sarah L;
Centenera, Margaret M;
Tilley, Wayne D;
Selth, Luke A;
Butler, Lisa M

Publication type:

journal article

TRanscriptome ANalysis of StratifiEd CohorTs (TRANSECT) enables automated assessment of global gene regulation linked to disparate expression in user defined genes and gene sets Open Access.

Published in:

NAR Genomics & Bioinformatics, 2025, v. 7, n. 2, p. 1, doi. 10.1093/nargab/lqaf041

By:

Toubia, John;
Kusay, Yasir;
Maqsood, Muneeza;
Warnock, Nicholas I;
Lawrence, David M;
Bracken, Cameron P;
Gregory, Philip A;
Kan, Winnie L;
Selth, Luke A;
Conn, Simon J;
Lopez, Angel F;
Branford, Susan;
Scott, Hamish S;
Kok, Chung Hoow;
Goodall, Gregory J;
Schreiber, Andreas W

Publication type:

Article

Impact of positive surgical margin location after radical prostatectomy: a network meta-analysis.

Published in:

2025

By:

John, Athul;
Milton, Thomas;
Gupta, Aashray;
Nguyen, Mau T.;
Stretton, Brandon;
Hewitt, Joseph;
Virgin, James;
Kovoor, Joshua;
Catterwell, Rick;
Selth, Luke;
Callaghan, Michael O.

Publication type:

Literature Review

FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49234-9

By:

Wang, Zifeng;
Townley, Scott L.;
Zhang, Songqi;
Liu, Mingyu;
Li, Muqing;
Labaf, Maryam;
Patalano, Susan;
Venkataramani, Kavita;
Siegfried, Kellee R.;
Macoska, Jill A.;
Han, Dong;
Gao, Shuai;
Risbridger, Gail P.;
Taylor, Renea A.;
Lawrence, Mitchell G.;
He, Housheng Hansen;
Selth, Luke A.;
Cai, Changmeng

Publication type:

Article

Correction to: VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer.

Published in:

2019

By:

Holding, Andrew N.;
Giorgi, Federico M.;
Donnelly, Amanda;
Cullen, Amy E.;
Nagarajan, Sankari;
Selth, Luke A.;
Markowetz, Florian

Publication type:

Correction Notice

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer.

Published in:

Genome Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13059-019-1698-z

By:

Holding, Andrew N.;
Giorgi, Federico M.;
Donnelly, Amanda;
Cullen, Amy E.;
Nagarajan, Sankari;
Selth, Luke A.;
Markowetz, Florian

Publication type:

Article

Functional Characterisation of the Circular RNA, circHTT(2-6) , in Huntington's Disease.

Published in:

Cells (2073-4409), 2023, v. 12, n. 9, p. 1337, doi. 10.3390/cells12091337

By:

Gantley, Laura;
Stringer, Brett W.;
Conn, Vanessa M.;
Ootsuka, Youichirou;
Holds, Duncan;
Slee, Mark;
Aliakbari, Kamelya;
Kirk, Kirsty;
Ormsby, Rebecca J.;
Webb, Stuart T.;
Hanson, Adrienne;
Lin, He;
Selth, Luke A.;
Conn, Simon J.

Publication type:

Article

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26612-1

By:

Che, Meixia;
Chaturvedi, Aashi;
Munro, Sarah A.;
Pitzen, Samuel P.;
Ling, Alex;
Zhang, Weijie;
Mentzer, Josh;
Ku, Sheng-Yu;
Puca, Loredana;
Zhu, Yanyun;
Bergman, Andries M.;
Severson, Tesa M.;
Forster, Colleen;
Liu, Yuzhen;
Hildebrand, Jacob;
Daniel, Mark;
Wang, Ting-You;
Selth, Luke A.;
Hickey, Theresa;
Zoubeidi, Amina

Publication type:

Article

The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking.

Published in:

RNA Biology, 2024, v. 21, n. 1, p. 199, doi. 10.1080/15476286.2023.2294222

By:

Neumann, Daniel P.;
Pillman, Katherine A.;
Dredge, B. Kate;
Bert, Andrew G.;
Phillips, Caroline A.;
Lumb, Rachael;
Ramani, Yesha;
Bracken, Cameron P.;
Hollier, Brett G.;
Selth, Luke A.;
Beilharz, Traude H.;
Goodall, Gregory J.;
Gregory, Philip A.

Publication type:

Article

Data Mining of Small RNA-Seq Suggests an Association Between Prostate Cancer and Altered Abundance of 5′ Transfer RNA Halves in Seminal Fluid and Prostatic Tissues.

Published in:

Biomarkers in Cancer, 2018, v. 10, p. 1, doi. 10.1177/1179299X18759545

By:

Dhahbi, Joseph M.;
Atamna, Hani;
Selth, Luke A.

Publication type:

Article

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.62592

By:

Gillis, Joanna L.;
Hinneh, Josephine A.;
Ryan, Natalie K.;
Irani, Swati;
Moldovan, Max;
Quek, Lake-Ee;
Shrestha, Raj K.;
Hanson, Adrienne R.;
Jianling Xie;
Hoy, Andrew J.;
Holst, Jeff;
Centenera, Margaret M.;
Mills, Ian G.;
Lynn, David J.;
Selth, Luke A.;
Butler, Lisa M.

Publication type:

Article

Primary Gleason grade and Gleason grade group at positive surgical margins: a systematic review and meta‐analysis.

Published in:

BJU International, 2021, v. 127, p. 13, doi. 10.1111/bju.15316

By:

John, Athul;
John, Hritik;
Catterwell, Rick;
Selth, Luke A;
Callaghan, Michael O

Publication type:

Article

Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression.

Published in:

EMBO Journal, 2019, v. 38, n. 23, p. N.PAG, doi. 10.15252/embj.2018101323

By:

Lorent, Julie;
Kusnadi, Eric P;
Hoef, Vincent;
Rebello, Richard J;
Leibovitch, Matthew;
Ristau, Johannes;
Chen, Shan;
Lawrence, Mitchell G;
Szkop, Krzysztof J;
Samreen, Baila;
Balanathan, Preetika;
Rapino, Francesca;
Close, Pierre;
Bukczynska, Patricia;
Scharmann, Karin;
Takizawa, Itsuhiro;
Risbridger, Gail P;
Selth, Luke A;
Leidel, Sebastian A;
Lin, Qishan

Publication type:

Article

miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking.

Published in:

EMBO Journal, 2018, v. 37, n. 13, p. 1, doi. 10.15252/embj.201899016

By:

Pillman, Katherine A.;
Phillips, Caroline A.;
Roslan, Suraya;
Toubia, John;
Dredge, B. Kate;
Bert, Andrew G.;
Lumb, Rachael;
Neumann, Daniel P.;
Li, Xiaochun;
Conn, Simon J.;
Liu, Dawei;
Bracken, Cameron P.;
Lawrence, David M.;
Stylianou, Nataly;
Schreiber, Andreas W.;
Tilley, Wayne D.;
Hollier, Brett G.;
Khew‐Goodall, Yeesim;
Selth, Luke A.;
Goodall, Gregory J.

Publication type:

Article

Somatostatin receptor subtype 1 as a potential diagnostic marker and therapeutic target in prostate cancer.

Published in:

Prostate, 2017, v. 77, n. 15, p. 1499, doi. 10.1002/pros.23426

By:

Pedraza‐Arévalo, Sergio;
Hormaechea‐Agulla, Daniel;
Gómez‐Gómez, Enrique;
Requena, María J.;
Selth, Luke A.;
Gahete, Manuel D.;
Castaño, Justo P.;
Luque, Raul M.

Publication type:

Article

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.

Published in:

Prostate, 2016, v. 76, n. 16, p. 1546, doi. 10.1002/pros.23239

By:

Armstrong, Heather K.;
Koay, Yen Chin;
Irani, Swati;
Das, Rajdeep;
Nassar, Zeyad D.;
Selth, Luke A.;
Centenera, Margaret M.;
McAlpine, Shelli R.;
Butler, Lisa M.

Publication type:

Article

Diagnostic Performance of Expression of PCA3, Hepsin and miR Biomarkers Inejaculate in Combination With Serum PSA for the Detection of Prostate Cancer.

Published in:

Prostate, 2015, v. 75, n. 5, p. 539, doi. 10.1002/pros.22942

By:

Roberts, Matthew J.;
Chow, Clement W. K.;
Schirra, Horst Joachim;
Richards, Renee;
Buck, Marion;
Selth, Luke A.;
Doi, Suhail A. R.;
Samaratunga, Hema;
Perry‐Keene, Joanna;
Payton, Diane;
Yaxley, John;
Lavin, Martin F.;
Gardiner, Robert A.

Publication type:

Article

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

Published in:

Prostate, 2013, v. 73, n. 2, p. 182, doi. 10.1002/pros.22554

By:

Chiam, Karen;
Ryan, Natalie K.;
Ricciardelli, Carmela;
Day, Tanya K.;
Buchanan, Grant;
Ochnik, Aleksandra M.;
Murti, Krisna;
Selth, Luke A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Bianco‐Miotto, Tina

Publication type:

Article

Circulating MicroRNAs as Biomarkers of Prostate Cancer: The State of Play.

Published in:

Prostate Cancer (20903111), 2013, p. 1, doi. 10.1155/2013/539680

By:

Sapre, Nikhil;
Selth, Luke A.

Publication type:

Article

Corrigendum to “Agrobacterium tumefaciens supports DNA replication of diverse geminivirus types” [FEBS Lett. 516 (2002) 179–182]

Published in:

2011

By:

Selth, Luke A.;
Randles, John W.;
Ali Rezaian, M.

Publication type:

Correction Notice

An Rtt109-Independent Role for Vps75 in Transcription-Associated Nucleosome Dynamics.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 15, p. 4220, doi. 10.1128/MCB.01882-08

By:

Selth, Luke A.;
Lorch, Yahli;
Ocampo-Hafalla, Maria T.;
Mitter, Richard;
Shales, Michael;
Krogan, Nevan J.;
Kornberg, Roger D.;
Svejstrup, Jesper Q.

Publication type:

Article

Genome-wide mapping of ZNF652 promoter binding sites in breast cancer cells.

Published in:

Journal of Cellular Biochemistry, 2011, v. 112, n. 10, p. 2742, doi. 10.1002/jcb.23214

By:

Kumar, Raman;
Selth, Luke A.;
Schulz, Renee B.;
Tay, Bee Suan;
Neilsen, Paul M.;
Callen, David F.

Publication type:

Article

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

Published in:

International Journal of Cancer, 2013, v. 133, n. 12, p. 2812, doi. 10.1002/ijc.28310

By:

Trotta, Andrew P.;
Need, Eleanor F.;
Selth, Luke A.;
Chopra, Samarth;
Pinnock, Carole B.;
Leach, Damien A.;
Coetzee, Gerhard A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Buchanan, Grant

Publication type:

Article

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease.

Published in:

International Journal of Cancer, 2012, v. 131, n. 3, p. 662, doi. 10.1002/ijc.26414

By:

Thompson, Vanessa C.;
Day, Tanya K.;
Bianco-Miotto, Tina;
Selth, Luke A.;
Han, Guangzhou;
Thomas, Mervyn;
Buchanan, Grant;
Scher, Howard I.;
Nelson, Colleen C.;
Greenberg, Norman M.;
Butler, Lisa M.;
Tilley, Wayne D.

Publication type:

Article

Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease.

Published in:

International Journal of Cancer, 2012, v. 131, n. 3, p. 652, doi. 10.1002/ijc.26405

By:

Selth, Luke A.;
Townley, Scott;
Gillis, Joanna L.;
Ochnik, Aleksandra M.;
Murti, Krisna;
Macfarlane, Robyn J.;
Chi, Kim N.;
Marshall, Villis R.;
Tilley, Wayne D.;
Butler, Lisa M.

Publication type:

Article

Targeting lipid metabolism in metastatic prostate cancer.

Published in:

Therapeutic Advances in Medical Oncology, 2023, p. 1, doi. 10.1177/17588359231152839

By:

Scheinberg, Tahlia;
Mak, Blossom;
Butler, Lisa;
Selth, Luke;
Horvath, Lisa G.

Publication type:

Article

Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer.

Published in:

British Journal of Cancer, 2023, v. 129, n. 8, p. 1350, doi. 10.1038/s41416-023-02406-8

By:

Hinneh, Josephine A.;
Gillis, Joanna L.;
Mah, Chui Yan;
Irani, Swati;
Shrestha, Raj K.;
Ryan, Natalie K.;
Atsushi, Enomoto;
Nassar, Zeyad D.;
Lynn, David J.;
Selth, Luke A.;
Kato, Masashi;
Centenera, Margaret M.;
Butler, Lisa M.

Publication type:

Article

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 12, p. 5880, doi. 10.1093/nar/gkv262

By:

Siu Chiu Chan;
Selth, Luke A.;
Yingming Li;
Nyquist, Michael D.;
Lu Miao;
Bradner, James E.;
Raj, Ganesh V.;
Tilley, Wayne D.;
Dehm, Scott M.

Publication type:

Article

Regulation of mRNA Translation by Hormone Receptors in Breast and Prostate Cancer.

Published in:

Cancers, 2021, v. 13, n. 13, p. 3254, doi. 10.3390/cancers13133254

By:

Xie, Jianling;
Kusnadi, Eric P.;
Furic, Luc;
Selth, Luke A.

Publication type:

Article

Functional Studies of the Yeast Med5, Med15 and Med16 Mediator Tail Subunits.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073137

By:

Larsson, Miriam;
Uvell, Hanna;
Sandström, Jenny;
Rydén, Patrik;
Selth, Luke A.;
Björklund, Stefan

Publication type:

Article

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.

Published in:

2016

By:

Asim, Mohammad;
Massie, Charles E.;
Orafidiya, Folake;
Pértega-Gomes, Nelma;
Warren, Anne Y.;
Esmaeili, Mohsen;
Selth, Luke A.;
Zecchini, Heather I.;
Luko, Katarina;
Qureshi, Arham;
Baridi, Ajoeb;
Menon, Suraj;
Madhu, Basetti;
Escriu, Carlos;
Lyons, Scott;
Vowler, Sarah L.;
Zecchini, Vincent R.;
Shaw, Greg;
Hessenkemper, Wiebke;
Russell, Roslin

Publication type:

journal article

SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control.

Published in:

Science Translational Medicine, 2020, v. 12, n. 559, p. 1, doi. 10.1126/scitranslmed.aaz8048

By:

Montgomery, Magdalene K.;
Bayliss, Jacqueline;
Devereux, Camille;
Bezawork-Geleta, Ayenachew;
Roberts, David;
Huang, Cheng;
Schittenhelm, Ralf B.;
Ryan, Andrew;
Townley, Scott L.;
Selth, Luke A.;
Biden, Trevor J.;
Steinberg, Gregory R.;
Samocha-Bonet, Dorit;
Meex, Ruth C. R.;
Watt, Matthew J.

Publication type:

Article

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.

Published in:

Science Translational Medicine, 2019, v. 11, n. 478, p. N.PAG, doi. 10.1126/scitranslmed.aau5758

By:

Watt, Matthew J.;
Clark, Ashlee K.;
Selth, Luke A.;
Haynes, Vanessa R.;
Lister, Natalie;
Rebello, Richard;
Porter, Laura H.;
Niranjan, Birunthi;
Whitby, Sarah T.;
Lo, Jennifer;
Huang, Cheng;
Schittenhelm, Ralf B.;
Anderson, Kimberley E.;
Furic, Luc;
Wijayaratne, Poornima R.;
Matzaris, Maria;
Montgomery, Magdalene K.;
Papargiris, Melissa;
Norden, Sam;
Febbraio, Maria

Publication type:

Article

Agrobacterium tumefaciens supports DNA replication of diverse geminivirus types

Published in:

FEBS Letters, 2002, v. 516, n. 1-3, p. 179, doi. 10.1016/S0014-5793(02)02539-5

By:

Selth, Luke A.;
Randles, John W.;
Rezaian, M. Ali

Publication type:

Article

The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype.

Published in:

2015

By:

Need, Eleanor F.;
Selth, Luke A.;
Trotta, Andrew P.;
Leach, Damien A.;
Giorgio, Lauren;
O'Loughlin, Melissa A.;
Smith, Eric;
Gill, Peter G.;
Ingman, Wendy V.;
Graham, J. Dinny;
Buchanan, Grant

Publication type:

journal article

Optical Cellular Micromotion: A New Paradigm to Measure Tumor Cells Invasion within Gels Mimicking the 3D Tumor Environments.

Published in:

Small Methods, 2022, v. 6, n. 8, p. 1, doi. 10.1002/smtd.202200471

By:

Guo, Zhaobin;
Yang, Chih‐Tsung;
Chien, Chia‐Chi;
Selth, Luke A.;
Bagnaninchi, Pierre O.;
Thierry, Benjamin

Publication type:

Article

TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.

Published in:

Cellular & Molecular Life Sciences, 2021, v. 78, n. 8, p. 4035, doi. 10.1007/s00018-021-03825-7

By:

Xie, Jianling;
De Poi, Stuart P.;
Humphrey, Sean J.;
Hein, Leanne K.;
Bruning, John B.;
Pan, Wenru;
Selth, Luke A.;
Sargeant, Timothy J.;
Proud, Christopher G.

Publication type:

Article