Works by Selt, Florian

Results: 27
    1
    2

    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.

    Published in:
    Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
    By:
    • Ecker, Jonas;
    • Oehme, Ina;
    • Mazitschek, Ralph;
    • Korshunov, Andrey;
    • Kool, Marcel;
    • Hielscher, Thomas;
    • Kiss, Judit;
    • Selt, Florian;
    • Konrad, Carina;
    • Lodrini, Marco;
    • Deubzer, Hedwig E.;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
    3

    MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40235-8
    By:
    • Sigaud, Romain;
    • Albert, Thomas K.;
    • Hess, Caroline;
    • Hielscher, Thomas;
    • Winkler, Nadine;
    • Kocher, Daniela;
    • Walter, Carolin;
    • Münter, Daniel;
    • Selt, Florian;
    • Usta, Diren;
    • Ecker, Jonas;
    • Brentrup, Angela;
    • Hasselblatt, Martin;
    • Thomas, Christian;
    • Varghese, Julian;
    • Capper, David;
    • Thomale, Ulrich W.;
    • Hernáiz Driever, Pablo;
    • Simon, Michèle;
    • Horn, Svea
    Publication type:
    Article
    4

    Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.

    Published in:
    Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326
    By:
    • Selt, Florian;
    • Deiß, Alica;
    • Korshunov, Andrey;
    • Capper, David;
    • Witt, Hendrik;
    • van Tilburg, Cornelis M.;
    • Jones, David T. W.;
    • Witt, Ruth;
    • Sahm, Felix;
    • Reuss, David;
    • Kölsche, Christian;
    • Ecker, Jonas;
    • Oehme, Ina;
    • Hielscher, Thomas;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
    5
    6

    Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10.

    Published in:
    2025
    By:
    • Hirsch, Steffen;
    • Rahmanzade, Ramin;
    • Grund, Kerstin;
    • Sutter, Christian;
    • Schramm, Kathrin;
    • Selt, Florian;
    • Ecker, Jonas;
    • Jones, Barbara C.;
    • Schrimpf, Daniel;
    • Demmert, Martin;
    • Guerreiro Stücklin, Ana S.;
    • Hernaiz Driever, Pablo;
    • Mezger, Markus;
    • Brecht, Ines;
    • Adib, Sasan D.;
    • Brummel, Bastian;
    • Sturm, Dominik;
    • Dikow, Nicola;
    • Hempel, Maja;
    • Milde, Till
    Publication type:
    Letter
    7

    Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 4, p. 551, doi. 10.1007/s00401-023-02626-5
    By:
    • Picard, Daniel;
    • Felsberg, Jörg;
    • Langini, Maike;
    • Stachura, Paweł;
    • Qin, Nan;
    • Macas, Jadranka;
    • Reiss, Yvonne;
    • Bartl, Jasmin;
    • Selt, Florian;
    • Sigaud, Romain;
    • Meyer, Frauke-D.;
    • Stefanski, Anja;
    • Stühler, Kai;
    • Roque, Lucia;
    • Roque, Rafael;
    • Pandyra, Aleksandra A.;
    • Brozou, Triantafyllia;
    • Knobbe-Thomsen, Christiane;
    • Plate, Karl H.;
    • Roesch, Alexander
    Publication type:
    Article
    8

    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 5, p. 667, doi. 10.1007/s00401-023-02558-0
    By:
    • Bogumil, Henri;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Ismer, Britta;
    • Blume, Christina;
    • Rahmanzade, Ramin;
    • Hinz, Felix;
    • Cherkezov, Asan;
    • Banan, Rouzbeh;
    • Friedel, Dennis;
    • Reuss, David E.;
    • Selt, Florian;
    • Ecker, Jonas;
    • Milde, Till;
    • Pajtler, Kristian W.;
    • Schittenhelm, Jens;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther
    Publication type:
    Article
    9

    Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 1, p. 97, doi. 10.1007/s00401-022-02522-4
    By:
    • Mynarek, Martin;
    • Obrecht, Denise;
    • Sill, Martin;
    • Sturm, Dominik;
    • Kloth-Stachnau, Katja;
    • Selt, Florian;
    • Ecker, Jonas;
    • von Hoff, Katja;
    • Juhnke, Björn-Ole;
    • Goschzik, Tobias;
    • Pietsch, Torsten;
    • Bockmayr, Michael;
    • Kool, Marcel;
    • von Deimling, Andreas;
    • Witt, Olaf;
    • Schüller, Ulrich;
    • Benesch, Martin;
    • Gerber, Nicolas U.;
    • Sahm, Felix;
    • Jones, David T. W.
    Publication type:
    Article
    10

    GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 6, p. 1065, doi. 10.1007/s00401-021-02369-1
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Sturm, Dominik;
    • Selt, Florian;
    • Ecker, Jonas;
    • Kazdal, Daniel;
    • Miele, Evelina;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Kohlhof-Meinecke, Patricia;
    • Beschorner, Rudi;
    • Kramm, Christof M.;
    • Hasselblatt, Martin;
    • Reifenberger, Guido;
    • Capper, David;
    • Wesseling, Pieter;
    • Stenzinger, Albrecht;
    • Milde, Till
    Publication type:
    Article
    11

    Clinical outcome of pediatric medulloblastoma patients with Li–Fraumeni syndrome.

    Published in:
    Neuro-Oncology, 2023, v. 25, n. 12, p. 2273, doi. 10.1093/neuonc/noad114
    By:
    • Kolodziejczak, Anna S;
    • Guerrini-Rousseau, Lea;
    • Planchon, Julien Masliah;
    • Ecker, Jonas;
    • Selt, Florian;
    • Mynarek, Martin;
    • Obrecht, Denise;
    • Sill, Martin;
    • Autry, Robert J;
    • Stutheit-Zhao, Eric;
    • Hirsch, Steffen;
    • Amouyal, Elsa;
    • Dufour, Christelle;
    • Ayrault, Olivier;
    • Torrejon, Jacob;
    • Waszak, Sebastian M;
    • Ramaswamy, Vijay;
    • Pentikainen, Virve;
    • Demir, Haci Ahmet;
    • Clifford, Steven C
    Publication type:
    Article
    12

    BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.

    Published in:
    Neuro-Oncology, 2023, v. 25, n. 4, p. 735, doi. 10.1093/neuonc/noac199
    By:
    • Selt, Florian;
    • Sigaud, Romain;
    • Valinciute, Gintvile;
    • Sievers, Philipp;
    • Zaman, Julia;
    • Alcon, Clara;
    • Schmid, Simone;
    • Peterziel, Heike;
    • Tsai, Jessica W;
    • Guiho, Romain;
    • Martínez-Barbera, Juan Pedro;
    • Pusch, Stefan;
    • Deng, Jing;
    • Zhai, Yifan;
    • Tilburg, Cornelis M van;
    • Schuhman, Martin U;
    • Damaty, Ahmed El;
    • Bandopadhayay, Pratiti;
    • Herold-Mende, Christel;
    • Deimling, Andreas von
    Publication type:
    Article
    13

    Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data.

    Published in:
    Neuropathology & Applied Neurobiology, 2021, v. 47, n. 3, p. 406, doi. 10.1111/nan.12683
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Sievers, Philipp;
    • Reinhardt, Annekathrin;
    • Suwala, Abigail K.;
    • Sill, Martin;
    • Reuss, David E.;
    • Korshunov, Andrey;
    • Casalini, Belén M.;
    • Sommerkamp, Alexander C.;
    • Ecker, Jonas;
    • Selt, Florian;
    • Sturm, Dominik;
    • Gnekow, Astrid;
    • Koch, Arend;
    • Simon, Michèle;
    • Hernáiz Driever, Pablo;
    • Schüller, Ulrich;
    • Capper, David;
    • Tilburg, Cornelis M.
    Publication type:
    Article
    14

    Soft Tissue Undifferentiated Sarcoma Carrying a Novel Onecut1::Nutm1 Fusion.

    Published in:
    Pediatric Blood & Cancer, 2025, v. 72, n. 1, p. 1, doi. 10.1002/pbc.31427
    By:
    • Filippidou, Maria;
    • Glentis, Stavros;
    • Rigatou, Efthymia;
    • Sievers, Philipp;
    • Selt, Florian;
    • Dimitriadis, Efthymios;
    • Perari, Panagiota;
    • Binenbaum, Ilona;
    • Avgerinou, Georgia;
    • van Tilburg, Cornelis M.;
    • Jones, David T. W.;
    • Sahm, Felix;
    • Milde, Till;
    • Witt, Olaf;
    • Pfister, Stefan M.;
    • Grünewald, Thomas G. P.;
    • Stefanaki, Kalliopi;
    • Kattamis, Antonis
    Publication type:
    Article
    15
    16

    Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 2, p. 226, doi. 10.1093/neuonc/noaa191
    By:
    • Ecker, Jonas;
    • Thatikonda, Venu;
    • Sigismondo, Gianluca;
    • Selt, Florian;
    • Valinciute, Gintvile;
    • Oehme, Ina;
    • Müller, Carina;
    • Buhl, Juliane L;
    • Ridinger, Johannes;
    • Usta, Diren;
    • Qin, Nan;
    • Tilburg, Cornelis M van;
    • Herold-Mende, Christel;
    • Remke, Marc;
    • Sahm, Felix;
    • Westermann, Frank;
    • Kool, Marcel;
    • Wechsler-Reya, Robert J;
    • Chavez, Lukas;
    • Krijgsveld, Jeroen
    Publication type:
    Article
    17
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    Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.

    Published in:
    Journal of Neuro-Oncology, 2024, v. 168, n. 2, p. 317, doi. 10.1007/s11060-024-04672-9
    By:
    • Kocher, Daniela;
    • Cao, Lei;
    • Guiho, Romain;
    • Langhammer, Melanie;
    • Lai, Yun-Lu;
    • Becker, Pauline;
    • Hamdi, Hiba;
    • Friedel, Dennis;
    • Selt, Florian;
    • Vonhören, David;
    • Zaman, Julia;
    • Valinciute, Gintvile;
    • Herter, Sonja;
    • Picard, Daniel;
    • Rettenmeier, Johanna;
    • Maass, Kendra K.;
    • Pajtler, Kristian W.;
    • Remke, Marc;
    • von Deimling, Andreas;
    • Pusch, Stefan
    Publication type:
    Article
    20
    21

    Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.

    Published in:
    Journal of Neuro-Oncology, 2023, v. 163, n. 1, p. 143, doi. 10.1007/s11060-023-04319-1
    By:
    • Valinciute, Gintvile;
    • Ecker, Jonas;
    • Selt, Florian;
    • Hielscher, Thomas;
    • Sigaud, Romain;
    • Ridinger, Johannes;
    • Thatikonda, Venu;
    • Gatzweiler, Charlotte;
    • Robinson, Sarah;
    • Talbot, Julie;
    • Bernardi, Flavia;
    • Picard, Daniel;
    • Blattner-Johnson, Mirjam;
    • Schmid, Simone;
    • Jones, David T.;
    • van Tilburg, Cornelis M.;
    • Capper, David;
    • Kool, Marcel;
    • Remke, Marc;
    • Oehme, Ina
    Publication type:
    Article
    22

    Response to trametinib treatment in progressive pediatric low-grade glioma patients.

    Published in:
    Journal of Neuro-Oncology, 2020, v. 149, n. 3, p. 499, doi. 10.1007/s11060-020-03640-3
    By:
    • Selt, Florian;
    • van Tilburg, Cornelis M.;
    • Bison, Brigitte;
    • Sievers, Philipp;
    • Harting, Inga;
    • Ecker, Jonas;
    • Pajtler, Kristian W.;
    • Sahm, Felix;
    • Bahr, Annabelle;
    • Simon, Michèle;
    • Jones, David T. W.;
    • Well, Lennart;
    • Mautner, Victor-Felix;
    • Capper, David;
    • Hernáiz Driever, Pablo;
    • Gnekow, Astrid;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
    23

    Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.

    Published in:
    Acta Neuropathologica, 2016, v. 131, n. 6, p. 903, doi. 10.1007/s00401-015-1519-8
    By:
    • Sahm, Felix;
    • Schrimpf, Daniel;
    • Jones, David;
    • Meyer, Jochen;
    • Kratz, Annekathrin;
    • Reuss, David;
    • Capper, David;
    • Koelsche, Christian;
    • Korshunov, Andrey;
    • Wiestler, Benedikt;
    • Buchhalter, Ivo;
    • Milde, Till;
    • Selt, Florian;
    • Sturm, Dominik;
    • Kool, Marcel;
    • Hummel, Manuela;
    • Bewerunge-Hudler, Melanie;
    • Mawrin, Christian;
    • Schüller, Ulrich;
    • Jungk, Christine
    Publication type:
    Article
    24
    25

    Sarcoma classification by DNA methylation profiling.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20603-4
    By:
    • Koelsche, Christian;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Sill, Martin;
    • Sahm, Felix;
    • Reuss, David E.;
    • Blattner, Mirjam;
    • Worst, Barbara;
    • Heilig, Christoph E.;
    • Beck, Katja;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Paff, Elke;
    • Stark, Sebastian;
    • Johann, Pascal;
    • Selt, Florian;
    • Ecker, Jonas;
    • Sturm, Dominik;
    • Pajtler, Kristian W.;
    • Reinhardt, Annekathrin
    Publication type:
    Article
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