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Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins.
- Published in:
- Nature, 1983, v. 304, n. 5928, p. 727, doi. 10.1038/304727a0
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- Publication type:
- Article
Performance characteristics of plasma amyloid-beta 40 and 42 assays.
- Published in:
- 2009
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- Publication type:
- journal article
Performance Characteristics of Plasma Amyloid-β 40 and 42 Assays.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 16, n. 2, p. 277, doi. 10.3233/JAD-2009-0948
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- Publication type:
- Article
Amyloid β-peptide is produced by cultured cells during normal metabolism: A reprise.
- Published in:
- Journal of Alzheimer's Disease, 2006, v. 9, n. 3, p. 163, doi. 10.3233/JAD-2006-9S319
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- Publication type:
- Article
Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β.
- Published in:
- EMBO Molecular Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.15252/emmm.202217061
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- Publication type:
- Article
Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β.
- Published in:
- EMBO Molecular Medicine, 2018, v. 10, n. 9, p. 1, doi. 10.15252/emmm.201808931
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- Publication type:
- Article
The amyloid hypothesis of Alzheimer's disease at 25 years.
- Published in:
- EMBO Molecular Medicine, 2016, v. 8, n. 6, p. 595, doi. 10.15252/emmm.201606210
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- Publication type:
- Article
The Origins of Alzheimer Disease.
- Published in:
- 2000
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- Publication type:
- Editorial
A calcium-sensitive antibody isolates soluble amyloid-β aggregates and fibrils from Alzheimer's disease brain.
- Published in:
- 2022
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- Publication type:
- journal article
Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain.
- Published in:
- 2019
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- Publication type:
- journal article
Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.
- Published in:
- 2015
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- Publication type:
- journal article
A Seed for Alzheimer Amyloid in the Brain.
- Published in:
- Journal of Neuroscience, 2004, v. 24, n. 20, p. 4894, doi. 10.1523/JNEUROSCI.0861-04.2004
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- Publication type:
- Article
Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5.
- Published in:
- Journal of Neuroscience, 2004, v. 24, n. 13, p. 3370, doi. 10.1523/JNEUROSCI.1633-03.2004
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- Publication type:
- Article
Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1573, doi. 10.1002/alz.13557
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- Publication type:
- Article
Comparing the effectiveness of a brief observational study protocol versus a telephone call for Alzheimer's disease prevention trial prescreening.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082745
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- Publication type:
- Article
Utilizing low‐volume PBMC samples from Alzheimer's disease clinical research cohorts for immune cell RNA‐sequencing.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082614
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- Publication type:
- Article
A brief questionnaire of self‐reported cognitive decline predicts MMSE and study partner QDRS: findings from the Davis Memory and Aging Cohort at Mass General Brigham.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082511
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- Publication type:
- Article
Plasma NT1‐tau and Aβ<sub>42</sub> correlate with age and cognitive function in two large Down syndrome cohorts.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5755, doi. 10.1002/alz.13382
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- Publication type:
- Article
Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 1, p. 79, doi. 10.1002/alz.12646
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- Publication type:
- Article
An oligomer‐directed Aβ antibody decreases synaptotoxic oligomeric Aβ in brain and improves behavioral abnormality in humanized APP knock‐in mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069066
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- Publication type:
- Article
Treatment of Alzheimer's disease by modulation of microglial neuroinflammation by nasal anti‐CD3 mAb.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068761
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- Publication type:
- Article
Plasma Biomarkers of Neurodegeneration and Tau in Relation to Longitudinal Depressive Symptoms in Older Adults: Findings from the Harvard Aging Brain Study.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.060979
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- Publication type:
- Article
An ultra‐sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1186, doi. 10.1002/alz.12457
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- Publication type:
- Article
Non‐denaturing affinity purification of soluble oligomeric Aβ from human brain using a novel calcium‐sensitive monoclonal antibody.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051725
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- Publication type:
- Article
Plasma levels of an N‐terminal tau fragment are highly associated with future cognitive decline and neurodegeneration in clinically normal elderly: Biomarkers (non‐neuroimaging): Blood based biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045261
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- Publication type:
- Article
Predicting development of AD clinical symptoms and their progression through a collection of novel plasma Aβ immunoassays: Biomarkers (non‐neuroimaging): Blood based biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043670
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- Publication type:
- Article
Transcriptomic correlates of neurite degeneration due to human brain‐derived Aβ and protection by clinical anti‐Aβ antibodies: Molecular and cell biology/APP/Abeta/amyloid.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043057
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- Publication type:
- Article
Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half‐life.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 9, p. 1183, doi. 10.1016/j.jalz.2019.06.3918
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- Publication type:
- Article
P1‐218: A NOVEL CELLULAR COMPLEX OF BACE1 AND γ‐SECRETASE SEQUENTIALLY GENERATES Aβ FROM APP.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P320, doi. 10.1016/j.jalz.2019.06.773
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- Publication type:
- Article
Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 3, p. 487, doi. 10.1016/j.jalz.2018.09.010
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- Publication type:
- Article
DT‐02‐03: TARGET ENGAGEMENT IN AN AD TRIAL: CRENEZUMAB LOWERS Aβ OLIGOMER LEVELS IN CSF.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1669, doi. 10.1016/j.jalz.2018.07.012
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- Publication type:
- Article
P1‐106: A HEAD‐TO‐HEAD COMPARISON OF LEAD CLINICAL ANTI‐Aβ ANTIBODIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P312, doi. 10.1016/j.jalz.2018.06.109
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- Publication type:
- Article
Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 663, doi. 10.3390/ijms19030663
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- Publication type:
- Article
Normal Cellular Processing of the β-Amyloid Precursor Protein Results in the Secretion of the Amyloid β Peptide and Related Molecules.
- Published in:
- Annals of the New York Academy of Sciences, 1993, v. 695, n. 1, p. 109, doi. 10.1111/j.1749-6632.1993.tb23037.x
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- Publication type:
- Article
Studies on the Relationship between Plasma Proteins and Amyloid Fibrils Found in Alzheimer's Disease.
- Published in:
- Annals of the New York Academy of Sciences, 1988, v. 529, n. 1, p. 233, doi. 10.1111/j.1749-6632.1988.tb51468.x
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- Publication type:
- Article
Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS.
- Published in:
- Glia, 2013, v. 61, n. 6, p. 985, doi. 10.1002/glia.22490
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- Publication type:
- Article
Developing Preventive Therapies for Chronic Diseases: Lessons Learned from Alzheimer's Disease.
- Published in:
- Nutrition Reviews, 2007, v. 65, p. S239, doi. 10.1301/nr.2007.dec.S239-S243
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- Publication type:
- Article
Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers.
- Published in:
- Journal of Physiology, 2006, v. 572, n. 2, p. 477, doi. 10.1113/jphysiol.2005.103754
- By:
- Publication type:
- Article
The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.17578
- By:
- Publication type:
- Article
Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00593-7
- By:
- Publication type:
- Article
Imaging Alzheimer's amyloid.
- Published in:
- Nature Biotechnology, 2000, v. 18, n. 8, p. 823, doi. 10.1038/78422
- By:
- Publication type:
- Article
Resolving controversies on the path to Alzheimer's therapeutics.
- Published in:
- 2011
- By:
- Publication type:
- Correction Notice
Resolving controversies on the path to Alzheimer's therapeutics.
- Published in:
- 2011
- By:
- Publication type:
- Correction Notice
Resolving controversies on the path to Alzheimer's therapeutics.
- Published in:
- 2011
- By:
- Publication type:
- Opinion
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
- Published in:
- Nature Medicine, 2008, v. 14, n. 8, p. 837, doi. 10.1038/nm1782
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- Publication type:
- Article
The ups and downs of Aβ.
- Published in:
- Nature Medicine, 2006, v. 12, n. 7, p. 758, doi. 10.1038/nm0706-758
- By:
- Publication type:
- Article
Dopamine covalently modifies and functionally inactivates parkin.
- Published in:
- Nature Medicine, 2005, v. 11, n. 11, p. 1214, doi. 10.1038/nm1314
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- Publication type:
- Article
Amyloidßprotein immunotherapy neutralizes Aßoligomers that disrupt synaptic plasticity in vivo.
- Published in:
- Nature Medicine, 2005, v. 11, n. 5, p. 556, doi. 10.1038/nm1234
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- Publication type:
- Article
TREATING ALZHEIMER’S DISEASE BY TARGETING β-AMYLOID: WHERE DO WE STAND?
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P545, doi. 10.1016/j.jalz.2017.07.137
- By:
- Publication type:
- Article
THE AMYLOID-B GENERATING TRI-PEPTIDE CLEAVAGE MECHANISM OF GAMMA-SECRETASE: IMPLICATIONS FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1041, doi. 10.1016/j.jalz.2016.06.2161
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- Publication type:
- Article