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ER‐aminopeptidase 1 determines the processing and presentation of an immunotherapy‐relevant melanoma epitope.
Published in:
European Journal of Immunology, 2020, v. 50, n. 2, p. 270, doi. 10.1002/eji.201948116
By:
- Textoris‐Taube, Kathrin;
- Cammann, Clemens;
- Henklein, Petra;
- Topfstedt, Eylin;
- Ebstein, Frédéric;
- Henze, Sarah;
- Liepe, Juliane;
- Zhao, Fang;
- Schadendorf, Dirk;
- Dahlmann, Burkhardt;
- Uckert, Wolfgang;
- Paschen, Annette;
- Mishto, Michele;
- Seifert, Ulrike
Publication type:
Article
The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognition.
Published in:
European Journal of Immunology, 2015, v. 45, n. 12, p. 3257, doi. 10.1002/eji.201445243
By:
- Keller, Martin;
- Ebstein, Frédéric;
- Bürger, Elke;
- Textoris‐Taube, Kathrin;
- Gorny, Xenia;
- Urban, Sabrina;
- Zhao, Fang;
- Dannenberg, Tanja;
- Sucker, Antje;
- Keller, Christin;
- Saveanu, Loredana;
- Krüger, Elke;
- Rothkötter, Hermann‐Josef;
- Dahlmann, Burkhardt;
- Henklein, Petra;
- Voigt, Antje;
- Kuckelkorn, Ulrike;
- Paschen, Annette;
- Kloetzel, Peter‐Michael;
- Seifert, Ulrike
Publication type:
Article
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C.
Published in:
Nature Medicine, 2000, v. 6, n. 5, p. 578, doi. 10.1038/75063
By:
- Takaki, Akinobu;
- Wiese, Manfred;
- Maertens, Geert;
- Depla, Erik;
- Seifert, Ulrike;
- Liebetrau, Anke;
- Miller, Jeffery L.;
- Manns, Michael P.;
- Rehermann, Barbara
Publication type:
Article
Recycling and Reshaping—E3 Ligases and DUBs in the Initiation of T Cell Receptor-Mediated Signaling and Response.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3424, doi. 10.3390/ijms23073424
By:
- Cammann, Clemens;
- Israel, Nicole;
- Slevogt, Hortense;
- Seifert, Ulrike
Publication type:
Article
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection.
Published in:
2006
By:
- Shin, Eui-Cheol;
- Seifert, Ulrike;
- Kato, Takanobu;
- Rice, Charles M;
- Feinstone, Stephen M;
- Kloetzel, Peter-M;
- Rehermann, Barbara
Publication type:
journal article
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection.
Published in:
Journal of Clinical Investigation, 2006, v. 116, n. 11, p. 3006, doi. 10.1172/JCI29832
By:
- Eui-Cheol Shin;
- Seifert, Ulrike;
- Kato, Takanobu;
- Rice, Charles M.;
- Feinstone, Stephen M.;
- Kloetzel, Peter-M.;
- Rehermann, Barbara
Publication type:
Article
Hepatitis C virus mutation affects proteasomal epitope processing.
Published in:
Journal of Clinical Investigation, 2004, v. 114, n. 2, p. 250, doi. 10.1172/JCI200420985
By:
- Seifert, Ulrike;
- Liermann, Heike;
- Racanelli, Vito;
- Halenius, Anne;
- Wiese, Manfred;
- Wedemeyer, Heiner;
- Ruppert, Thomas;
- Rispeter, Kay;
- Henklein, Peter;
- Sijts, Alice;
- Hengel, Hartmut;
- Kloetzel, Peter-M.;
- Rehermann, Barbara
Publication type:
Article
T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.958616
By:
- Cammann, Clemens;
- Israel, Nicole;
- Frentzel, Sarah;
- Jeron, Andreas;
- Topfstedt, Eylin;
- Schüler, Thomas;
- Simeoni, Luca;
- Zenker, Martin;
- Fehling, Hans Joerg;
- Schraven, Burkhart;
- Bruder, Dunja;
- Seifert, Ulrike
Publication type:
Article
Streptococcus pneumoniae and Influenza A Virus Co-Infection Induces Altered Polyubiquitination in A549 Cells.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.817532
By:
- Sura, Thomas;
- Gering, Vanessa;
- Cammann, Clemens;
- Hammerschmidt, Sven;
- Maaß, Sandra;
- Seifert, Ulrike;
- Becher, Dörte
Publication type:
Article
Consequences of COP9 signalosome and 26S proteasome interaction.
Published in:
FEBS Journal, 2005, v. 272, n. 15, p. 3909, doi. 10.1111/j.1742-4658.2005.04807.x
By:
- Xiaohua Huang;
- Hetfeld, Bettina K. J.;
- Seifert, Ulrike;
- Kähne, Thilo;
- Kloetzel, Peter-Michael;
- Naumann, Michael;
- Bech-Otschir, Dawadschargal;
- Dubiel, Wolfgang
Publication type:
Article
Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.
Published in:
Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0293-8
By:
- Möhle, Luisa;
- Schlüter, Dirk;
- Dunay, Ildiko Rita;
- Montag, Dirk;
- Israel, Nicole;
- Seifert, Ulrike;
- Müller, Andreas;
- Paarmann, Kristin;
- Krohn, Markus;
- Pahnke, Jens;
- Pietkiewicz, Sabine;
- Lavrik, Inna N.;
- Buguliskis, Jeffrey S.;
- Gundelfinger, Eckart D.;
- Schott, Björn H.
Publication type:
Article
Exposure to Melan-A/MART-126-35 tumor epitope specific CD8+T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS).
Published in:
Scientific Reports, 2016, p. 25208, doi. 10.1038/srep25208
By:
- Ebstein, Frédéric;
- Keller, Martin;
- Paschen, Annette;
- Walden, Peter;
- Seeger, Michael;
- Bürger, Elke;
- Krüger, Elke;
- Schadendorf, Dirk;
- Kloetzel, Peter-M.;
- Seifert, Ulrike
Publication type:
Article
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population.
Published in:
PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009287
By:
- Mishto, Michele;
- Bellavista, Elena;
- Ligorio, Claudia;
- Textoris-Taube, Kathrin;
- Santoro, Aurelia;
- Giordano, Mara;
- D'Alfonso, Sandra;
- Listi`, Florinda;
- Nacmias, Benedetta;
- Cellini, Elena;
- Leone, Maurizio;
- Grimaldi, Luigi M.E.;
- Fenoglio, Chiara;
- Esposito, Federica;
- Martinelli-Boneschi, Filippo;
- Galimberti, Daniela;
- Scarpini, Elio;
- Seifert, Ulrike;
- Amato, Maria Pia;
- Caruso, Calogero
Publication type:
Article
Interferon-γ, the functional plasticity of the ubiquitin–proteasome system, and MHC class I antigen processing.
Published in:
Immunological Reviews, 2005, v. 207, n. 1, p. 19, doi. 10.1111/j.0105-2896.2005.00308.x
By:
- Strehl, Britta;
- Seifert, Ulrike;
- Kr¨ger, Elke;
- Heink, Sylvia;
- Kuckelkorn, Ulrike;
- Kloetzel, Peter-M.
Publication type:
Article
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
Published in:
2020
By:
- Such, Lina;
- Zhao, Fang;
- Liu, Derek;
- Thier, Beatrice;
- Khanh Le-Trilling, Vu Thuy;
- Sucker, Antje;
- Coch, Christoph;
- Pieper, Natalia;
- Howe, Sebastian;
- Bhat, Hilal;
- Kalkavan, Halime;
- Ritter, Cathrin;
- Brinkhaus, Robin;
- Ugurel, Selma;
- Köster, Johannes;
- Seifert, Ulrike;
- Dittmer, Ulf;
- Schuler, Martin;
- Lang, Karl S.;
- Kufer, Thomas A.
Publication type:
journal article
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.
Published in:
Nature Immunology, 2011, v. 12, n. 1, p. 45, doi. 10.1038/ni.1974
By:
- Kessler, Jan H;
- Khan, Selina;
- Seifert, Ulrike;
- Le Gall, Sylvie;
- Chow, K Martin;
- Paschen, Annette;
- Bres-Vloemans, Sandra A;
- de Ru, Arnoud;
- van Montfoort, Nadine;
- Franken, Kees L M C;
- Benckhuijsen, Willemien E;
- Brooks, Jill M;
- van Hall, Thorbald;
- Ray, Kallol;
- Mulder, Arend;
- Doxiadis, Ilias I N;
- van Swieten, Paul F;
- Overkleeft, Hermen S;
- Prat, Annik;
- Tomkinson, Birgitta
Publication type:
Article
An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.
Published in:
Nature Immunology, 2003, v. 4, n. 4, p. 375, doi. 10.1038/ni905
By:
- Seifert, Ulrike;
- Maranon, Concepcion;
- Shmueli, Ayelet;
- Desoutter, Jean-Francois;
- Wesoloski, Lisa;
- Janek, Katharina;
- Henklein, Peter;
- Diescher, Susanne;
- Andrieu, Muriel;
- de la Salle, Henri;
- Weinschenk, Toni;
- Schild, Hansjorg;
- Laderach, Diego;
- Galy, Anne;
- Haas, Gaby;
- Kloetzel, Peter-M.;
- Reiss, Yuval;
- Hosmalin, Anne
Publication type:
Article
LOW NEUROTOXICITY OF ONX-0914 SUPPORTS THE IDEA OF SPECIFIC IMMUNOPROTEASOME INHIBITION AS A SIDE-EFFECT-LIMITING, THERAPEUTIC STRATEGY.
Published in:
European Journal of Microbiology & Immunology, 2017, v. 7, n. 3, p. 234, doi. 10.1556/1886.2017.00025
By:
- von Brzezinski, Laura;
- Säring, Paula;
- Landgraf, Peter;
- Cammann, Clemens;
- Seifert, Ulrike;
- Dieterich, Daniela C.
Publication type:
Article
The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.619465
By:
- French, Timothy;
- Israel, Nicole;
- Düsedau, Henning Peter;
- Tersteegen, Anne;
- Steffen, Johannes;
- Cammann, Clemens;
- Topfstedt, Eylin;
- Dieterich, Daniela;
- Schüler, Thomas;
- Seifert, Ulrike;
- Dunay, Ildiko Rita
Publication type:
Article
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
Published in:
Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01907-7
By:
- Tubío-Santamaría, Nuria;
- Jayavelu, Ashok Kumar;
- Schnoeder, Tina M.;
- Eifert, Theresa;
- Hsu, Chen-Jen;
- Perner, Florian;
- Zhang, Qirui;
- Wenge, Daniela V.;
- Hansen, Fynn M.;
- Kirkpatrick, Joanna M.;
- Jyotsana, Nidhi;
- Lane, Steven W.;
- von Eyss, Björn;
- Deshpande, Aniruddha J.;
- Kühn, Michael W. M.;
- Schwaller, Juerg;
- Cammann, Clemens;
- Seifert, Ulrike;
- Ebstein, Frédéric;
- Krüger, Elke
Publication type:
Article
Invitation to cervical cancer screening does increase participation in Germany: Results from the MARZY study.
Published in:
International Journal of Cancer, 2016, v. 139, n. 5, p. 1018, doi. 10.1002/ijc.30146
By:
- Radde, Kathrin;
- Gottschalk, Andrea;
- Bussas, Ulrike;
- Schülein, Stefanie;
- Schriefer, Dirk;
- Seifert, Ulrike;
- Neumann, Anne;
- Kaiser, Melanie;
- Blettner, Maria;
- Klug, Stefanie J.
Publication type:
Article
Emerging roles of immunoproteasomes beyond MHC class I antigen processing.
Published in:
Cellular & Molecular Life Sciences, 2012, v. 69, n. 16, p. 2543, doi. 10.1007/s00018-012-0938-0
By:
- Ebstein, Frédéric;
- Kloetzel, Peter-Michael;
- Krüger, Elke;
- Seifert, Ulrike
Publication type:
Article
The platelet proteasome and immunoproteasome are stable in buffy‐coat derived platelet concentrates for up to 7 days.
Published in:
Transfusion, 2021, v. 61, n. 9, p. 2746, doi. 10.1111/trf.16605
By:
- Colberg, Lisa;
- Cammann, Clemens;
- Wesche, Jan;
- Topfstedt, Eylin;
- Seifert, Ulrike;
- Greinacher, Andreas
Publication type:
Article
IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.
Published in:
Journal of Innate Immunity, 2017, v. 9, n. 4, p. 403, doi. 10.1159/000469661
By:
- Schauer, anja E.;
- Klassert, Tilman E.;
- von Lachner, Carolin;
- Riebold, Diana;
- Schneeweiß, anne;
- Stock, Magdalena;
- Müller, Mario M.;
- Hammerschmidt, Sven;
- Bufler, Philip;
- Seifert, Ulrike;
- Dietert, Kristina;
- Dinarello, Charles a.;
- Nold, Marcel F.;
- Gruber, achim D.;
- Nold-Petry, Claudia a.;
- Slevogt, Hortense
Publication type:
Article
Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling.
Published in:
Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-018-0317-z
By:
- Lowinus, Theresa;
- Heidel, Florian H.;
- Bose, Tanima;
- Nimmagadda, Subbaiah Chary;
- Schnöder, Tina;
- Cammann, Clemens;
- Schmitz, Ingo;
- Seifert, Ulrike;
- Fischer, Thomas;
- Schraven, Burkhart;
- Bommhardt, Ursula
Publication type:
Article

Found: 25

ER‐aminopeptidase 1 determines the processing and presentation of an immunotherapy‐relevant melanoma epitope.

The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-1<sub>26-35</sub>-specific T-cell recognition.

Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C.

Recycling and Reshaping—E3 Ligases and DUBs in the Initiation of T Cell Receptor-Mediated Signaling and Response.

Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection.

Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection.

Hepatitis C virus mutation affects proteasomal epitope processing.

T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation.

Streptococcus pneumoniae and Influenza A Virus Co-Infection Induces Altered Polyubiquitination in A549 Cells.

Consequences of COP9 signalosome and 26S proteasome interaction.

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.

Exposure to Melan-A/MART-1<sub>26-35</sub> tumor epitope specific CD8<sup>+</sup>T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS).

Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population.

Interferon-γ, the functional plasticity of the ubiquitin–proteasome system, and MHC class I antigen processing.

Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.

An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

LOW NEUROTOXICITY OF ONX-0914 SUPPORTS THE IDEA OF SPECIFIC IMMUNOPROTEASOME INHIBITION AS A SIDE-EFFECT-LIMITING, THERAPEUTIC STRATEGY.

The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis.

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.

Invitation to cervical cancer screening does increase participation in Germany: Results from the MARZY study.

Emerging roles of immunoproteasomes beyond MHC class I antigen processing.

The platelet proteasome and immunoproteasome are stable in buffy‐coat derived platelet concentrates for up to 7 days.

IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of K<sub>v</sub>1.3 potassium channels, AKT and ERK1/2 signaling.