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Suppression of MyD88 disturbs gut microbiota and activates the NLR pathway and hence fails to ameliorate DSS-induced colitis.
- Published in:
- Precision Clinical Medicine, 2024, v. 7, n. 2, p. 1, doi. 10.1093/pcmedi/pbae013
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- Publication type:
- Article
cGMP‐dependent kinase 2, Na<sup>+</sup>/H<sup>+</sup> exchanger NHE3, and PDZ‐adaptor NHERF2 co‐assemble in apical membrane microdomains.
- Published in:
- Acta Physiologica, 2024, v. 240, n. 4, p. 1, doi. 10.1111/apha.14125
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- Publication type:
- Article
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-51397-w
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- Publication type:
- Article
Acceptability Criteria of Precision Medicine: Lessons From Patients' Experiences With the GUIDE-IBD Trial Regarding the Use of Mobile Health Technology.
- Published in:
- Crohn's & Colitis 360, 2023, v. 5, n. 4, p. 1, doi. 10.1093/crocol/otad068
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- Publication type:
- Article
The Anion Channel TMEM16a/Ano1 Modulates CFTR Activity, but Does Not Function as an Apical Anion Channel in Colonic Epithelium from Cystic Fibrosis Patients and Healthy Individuals.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 14214, doi. 10.3390/ijms241814214
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- Publication type:
- Article
Human Colonoid–Myofibroblast Coculture for Study of Apical Na + /H + Exchangers of the Lower Cryptal Neck Region.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4266, doi. 10.3390/ijms24054266
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- Publication type:
- Article
Reduced Hepatocyte Bicarbonate Output Accelerates Periductal Inflammation and Fibrosis in mdr2<sup>-/-</sup> Mouse Liver.
- Published in:
- Paracelsus Proceedings of Experimental Medicine (PPExMed), 2023, p. 99, doi. 10.33594/000000634
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- Publication type:
- Article
The NHE3 Inhibitor Tenapanor Prevents Intestinal Obstructions in CFTR-Deleted Mice.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9993, doi. 10.3390/ijms23179993
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- Publication type:
- Article
SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans.
- Published in:
- Cellular Oncology (2211-3428), 2022, v. 45, n. 3, p. 381, doi. 10.1007/s13402-022-00672-x
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- Publication type:
- Article
The Role of Plasma Membrane Sodium/Hydrogen Exchangers in Gastrointestinal Functions: Proliferation and Differentiation, Fluid/Electrolyte Transport and Barrier Integrity.
- Published in:
- Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.899286
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- Publication type:
- Article
Loss of luminal carbonic anhydrase XIV results in decreased biliary bicarbonate output, liver fibrosis, and cholangiocyte proliferation in mice.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2022, v. 474, n. 5, p. 529, doi. 10.1007/s00424-021-02659-3
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- Publication type:
- Article
Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10328-3
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- Publication type:
- Article
Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10328-3
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- Publication type:
- Article
Sodium/hydrogen‐exchanger‐2 modulates colonocyte lineage differentiation.
- Published in:
- Acta Physiologica, 2022, v. 234, n. 3, p. 1, doi. 10.1111/apha.13774
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- Publication type:
- Article
Inhibition of Na<sup>+</sup>/H<sup>+</sup> exchanger isoform 3 improves gut fluidity and alkalinity in cystic fibrosis transmembrane conductance regulator‐deficient and F508del mutant mice.
- Published in:
- British Journal of Pharmacology, 2021, v. 178, n. 5, p. 1018, doi. 10.1111/bph.15323
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- Publication type:
- Article
Anti-High Mobility Group Box 1 Neutralizing-Antibody Ameliorates Dextran Sodium Sulfate Colitis in Mice.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.585094
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- Publication type:
- Article
Slc26a3 deletion alters pH‐microclimate, mucin biosynthesis, microbiome composition and increases the TNFα expression in murine colon.
- Published in:
- Acta Physiologica, 2020, v. 230, n. 2, p. 1, doi. 10.1111/apha.13498
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- Publication type:
- Article
Association of Clinical Phenotypes in Haploinsufficiency A20 (HA20) With Disrupted Domains of A20.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.574992
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- Publication type:
- Article
A20 Haploinsufficiency in a Chinese Patient With Intestinal Behcet's Disease-Like Symptoms: A Case Report.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01414
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- Publication type:
- Article
Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD.
- Published in:
- PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231222
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- Publication type:
- Article
Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca<sup>2+</sup> signaling and IK<sub>Ca</sub> activation.
- Published in:
- Physiological Reports, 2020, v. 8, n. 1, p. N.PAG, doi. 10.14814/phy2.14337
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- Publication type:
- Article
Gunnar Flemström's legacy in intestinal bicarbonate secretion—A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion.
- Published in:
- Acta Physiologica, 2019, v. 227, n. 4, p. N.PAG, doi. 10.1111/apha.13321
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- Publication type:
- Article
Expression, Localization and Functional Activity of the Major Na<sup>+</sup>/H<sup>+</sup> Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe.
- Published in:
- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 5, p. 1017, doi. 10.33594/000000070
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- Publication type:
- Article
Villus Growth, Increased Intestinal Epithelial Sodium Selectivity, and Hyperaldosteronism Are Mechanisms of Adaptation in a Murine Model of Short Bowel Syndrome.
- Published in:
- 2019
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- Publication type:
- journal article
A Phase 2, Randomized, Placebo-Controlled Study Evaluating Matrix Metalloproteinase-9 Inhibitor, Andecaliximab, in Patients With Moderately to Severely Active Crohn’s Disease.
- Published in:
- Journal of Crohn's & Colitis, 2018, v. 12, n. 9, p. 1014, doi. 10.1093/ecco-jcc/jjy070
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- Publication type:
- Article
Restoration of mucosal integrity and epithelial transport function by concomitant anti-TNFα treatment in chronic DSS-induced colitis.
- Published in:
- Journal of Molecular Medicine, 2018, v. 96, n. 8, p. 831, doi. 10.1007/s00109-018-1658-1
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- Publication type:
- Article
Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
- Published in:
- Molecular Reproduction & Development, 2018, v. 85, n. 8/9, p. 682, doi. 10.1002/mrd.23055
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- Publication type:
- Article
Na<sup>+</sup>/H<sup>+</sup> exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells.
- Published in:
- Journal of Cellular Physiology, 2017, v. 232, n. 7, p. 1669, doi. 10.1002/jcp.25758
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- Publication type:
- Article
CD4 T Cell Dependent Colitis Exacerbation Following Re-Exposure of Mycobacterium avium ssp. paratuberculosis.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2017, v. 7, p. 1, doi. 10.3389/fcimb.2017.00075
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- Publication type:
- Article
IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes.
- Published in:
- Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00061
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- Publication type:
- Article
Clinical Effects of a Topically Applied Toll-like Receptor 9 Agonist in Active Moderate-to-Severe Ulcerative Colitis.
- Published in:
- Journal of Crohn's & Colitis, 2016, v. 10, n. 11, p. 1294, doi. 10.1093/ecco-jcc/jjw103
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- Publication type:
- Article
Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2016, v. 468, n. 8, p. 1419, doi. 10.1007/s00424-016-1836-3
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- Publication type:
- Article
Evidence for a causal link between adaptor protein PDZK1 downregulation and Na/H exchanger NHE3 dysfunction in human and murine colitis.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 8, p. 1795, doi. 10.1007/s00424-014-1608-x
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- Publication type:
- Article
Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO transport and reduces survival in CFTR-deficient mice.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 6, p. 1261, doi. 10.1007/s00424-014-1543-x
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- Publication type:
- Article
Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 12, p. 2269, doi. 10.1007/s00424-014-1474-6
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- Publication type:
- Article
The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 8, p. 1541, doi. 10.1007/s00424-013-1381-2
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- Publication type:
- Article
Erratum to: The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.
- Published in:
- 2014
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- Publication type:
- Erratum
Loss of carbonic anhydrase IX expression impairs gastric mucosal defence against luminal acid (1109.13).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1109.13
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- Publication type:
- Article
Absence of Slc26a9 results in altered tracheobronchial anion transport and high mortality in neonate mice (1181.7).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1181.7
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- Publication type:
- Article
Role of Na<sup>+</sup>‐HCO<sub>3</sub><sup>‐</sup> cotransporter NBCe1 (Slc4a4) in colonic pH<sub>i</sub> regulation and anion transport (893.38).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.893.38
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- Publication type:
- Article
Short-Term Regulation of Murine Colonic NBCe1-B (Electrogenic Na<sup>+</sup>/HCO<sub>3</sub><sup>−</sup> Cotransporter) Membrane Expression and Activity by Protein Kinase C.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092275
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- Publication type:
- Article
Differential Association of the Na/H<sup>+</sup> Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2013, v. 32, n. 5, p. 1386, doi. 10.1159/000356577
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- Publication type:
- Article
Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.
- Published in:
- Journal of Physiology, 2013, v. 591, n. 21, p. 5377, doi. 10.1113/jphysiol.2013.254854
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- Publication type:
- Article
cGMP-dependent kinase 2, Na<sup>+</sup>/H<sup>+</sup> regulatory factor 2, and Na<sup>+</sup>/H<sup>+</sup> exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane.
- Published in:
- 2013
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- Publication type:
- Abstract
Essential role of the electroneutral Na<sup>+</sup>-HCO<sub>3</sub><sup>−</sup> cotransporter NBCn1 in murine duodenal acid-base balance and colonic mucus layer build-up in vivo.
- Published in:
- Journal of Physiology, 2013, v. 591, n. 8, p. 2189, doi. 10.1113/jphysiol.2012.247874
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- Publication type:
- Article
Rescue of epithelial HCO<sub>3</sub><sup>−</sup> secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 21, p. 5317, doi. 10.1113/jphysiol.2012.232124
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- Publication type:
- Article
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 3629, doi. 10.1172/JCI60429
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- Publication type:
- Article
The electroneutral Na<sup>+</sup>:HCO<sub>3</sub><sup>−</sup> cotransporter NBCn1 is a major pH<sub>i</sub> regulator in murine duodenum.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 14, p. 3317, doi. 10.1113/jphysiol.2011.226506
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- Publication type:
- Article
Downregulation of the NHE3-Binding PDZ-Adaptor Protein PDZK1 Expression during Cytokine-Induced Inflammation in Interleukin-10-Deficient Mice.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040657
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- Publication type:
- Article
Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 10, p. 2333, doi. 10.1113/jphysiol.2011.220152
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- Publication type:
- Article