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Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response.
Published in:
Journal of Pathology, 2022, v. 258, n. 3, p. 312, doi. 10.1002/path.6002
By:
- Lazcanoiturburu, Nerea;
- García‐Sáez, Juan;
- González‐Corralejo, Carlos;
- Roncero, Cesáreo;
- Sanz, Julián;
- Martín‐Rodríguez, Carlos;
- Valdecantos, M Pilar;
- Martínez‐Palacián, Adoración;
- Almalé, Laura;
- Bragado, Paloma;
- Calero‐Pérez, Silvia;
- Fernández, Almudena;
- García‐Bravo, María;
- Guerra, Carmen;
- Montoliu, Lluis;
- Segovia, José Carlos;
- Valverde, Ángela M;
- Fabregat, Isabel;
- Herrera, Blanca;
- Sánchez, Aránzazu
Publication type:
Article
Development and Characterization of a Factor V-Deficient CRISPR Cell Model for the Correction of Mutations.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5802, doi. 10.3390/ijms23105802
By:
- Serrano, Luis Javier;
- Garcia-Arranz, Mariano;
- De Pablo-Moreno, Juan A.;
- Segovia, José Carlos;
- Olivera-Salazar, Rocío;
- Garcia-Olmo, Damián;
- Liras, Antonio
Publication type:
Article
Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD.
Published in:
American Journal of Hematology, 2022, v. 97, n. 3, p. E120, doi. 10.1002/ajh.26458
By:
- Schwartz, Jonathan D.;
- Barcellini, Wilma;
- Grace, Rachel F.;
- Bianchi, Paola;
- Zanella, Alberto;
- López Lorenzo, José Luis;
- Sevilla, Julián;
- Shah, Ami J.;
- Glader, Bertil;
- Nicoletti, Eileen;
- Navarro Ordoñez, Susana;
- Segovia, José Carlos
Publication type:
Article
Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease.
Published in:
Cellular & Molecular Life Sciences, 2023, v. 80, n. 8, p. 1, doi. 10.1007/s00018-023-04882-w
By:
- Miguez, Andrés;
- Gomis, Cinta;
- Vila, Cristina;
- Monguió-Tortajada, Marta;
- Fernández-García, Sara;
- Bombau, Georgina;
- Galofré, Mireia;
- García-Bravo, María;
- Sanders, Phil;
- Fernández-Medina, Helena;
- Poquet, Blanca;
- Salado-Manzano, Cristina;
- Roura, Santiago;
- Alberch, Jordi;
- Segovia, José Carlos;
- Allen, Nicholas D.;
- Borràs, Francesc E.;
- Canals, Josep M.
Publication type:
Article
The downregulated membrane expression of CD18 in CD34+ cells defines a primitive population of human hematopoietic stem cells.
Published in:
Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13287-020-01672-0
By:
- Mesa-Núñez, Cristina;
- Leon-Rico, Diego;
- Aldea, Montserrat;
- Damián, Carlos;
- Sanchez-Baltasar, Raquel;
- Sanchez, Rebeca;
- Alberquilla, Omaira;
- Segovia, José Carlos;
- Bueren, Juan Antonio;
- Almarza, Elena
Publication type:
Article
Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency.
Published in:
American Journal of Hematology, 2019, v. 94, n. 1, p. 149, doi. 10.1002/ajh.25325
By:
- Bianchi, Paola;
- Fermo, Elisa;
- Glader, Bertil;
- Kanno, Hitoshi;
- Agarwal, Archana;
- Barcellini, Wilma;
- Eber, Stefan;
- Hoyer, James D.;
- Kuter, David J.;
- Maia, Tabita Magalhães;
- Mañu‐Pereira, Maria del Mar;
- Kalfa, Theodosia A.;
- Pissard, Serge;
- Segovia, José‐Carlos;
- van Beers, Eduard;
- Gallagher, Patrick G.;
- Rees, David C.;
- van Wijk, Richard
Publication type:
Article
Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach.
Published in:
Integrative Biology, 2017, v. 9, n. 6, p. 548, doi. 10.1039/c7ib00060j
By:
- Ma, Yuan;
- Han, Xin;
- Quintana Bustamante, Oscar;
- Bessa de Castro, Ricardo;
- Zhang, Kai;
- Zhang, Pengchao;
- Li, Ying;
- Liu, Zongbin;
- Liu, Xuewu;
- Ferrari, Mauro;
- Hu, Zhongbo;
- Carlos Segovia, José;
- Qin, Lidong
Publication type:
Article
Ex vivo expansion of umbilical cord blood (UCB) CD34<sup>+</sup> cells alters the expression and function of α4β1 and α5β1 integrins.
Published in:
British Journal of Haematology, 2001, v. 115, n. 1, p. 213, doi. 10.1046/j.1365-2141.2001.03084.x
By:
- Ramírez, Manuel;
- Segovia, José Carlos;
- Benet, Isana;
- Arbona, Cristina;
- Güenechea, Guillermo;
- Blaya, Carolina;
- García-Conde, Javier;
- Bueren, Juan A.;
- Prosper, Felipe
Publication type:
Article
Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation.
Published in:
Molecular Neurobiology, 2020, v. 57, n. 6, p. 2766, doi. 10.1007/s12035-020-01907-4
By:
- Comella-Bolla, Andrea;
- Orlandi, Javier G.;
- Miguez, Andrés;
- Straccia, Marco;
- García-Bravo, María;
- Bombau, Georgina;
- Galofré, Mireia;
- Sanders, Phil;
- Carrere, Jordi;
- Segovia, José Carlos;
- Blasi, Joan;
- Allen, Nicholas D.;
- Alberch, Jordi;
- Soriano, Jordi;
- Canals, Josep M.
Publication type:
Article

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