Works matching AU Segatto, Marco

Results: 58

Exploration of Bromodomain Proteins as Drug Targets for Niemann–Pick Type C Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5769, doi. 10.3390/ijms26125769

By:

Parente, Martina;
Barthelemy, Amélie;
Tonini, Claudia;
Caputo, Sara;
Sacchi, Alessandra;
Leone, Stefano;
Segatto, Marco;
Pfrieger, Frank W.;
Pallottini, Valentina

Publication type:

Article

p75NTR Modulation Reduces Oxidative Stress and the Expression of Pro-Inflammatory Mediators in a Cell Model of Rett Syndrome.

Published in:

Biomedicines, 2024, v. 12, n. 11, p. 2624, doi. 10.3390/biomedicines12112624

By:

Varone, Michela;
Scavo, Giuseppe;
Colardo, Mayra;
Martella, Noemi;
Pensabene, Daniele;
Bisesto, Emanuele;
Del Busso, Andrea;
Segatto, Marco

Publication type:

Article

Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich's Ataxia Pre-Clinical Models and Clinical Trials.

Published in:

Biomedicines, 2023, v. 11, n. 5, p. 1293, doi. 10.3390/biomedicines11051293

By:

Tiberi, Jessica;
Segatto, Marco;
Fiorenza, Maria Teresa;
La Rosa, Piergiorgio

Publication type:

Article

Bromodomain and Extra-Terminal Proteins in Brain Physiology and Pathology: BET-ing on Epigenetic Regulation.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 750, doi. 10.3390/biomedicines11030750

By:

Martella, Noemi;
Pensabene, Daniele;
Varone, Michela;
Colardo, Mayra;
Petraroia, Michele;
Sergio, William;
La Rosa, Piergiorgio;
Moreno, Sandra;
Segatto, Marco

Publication type:

Article

NGF Prevents Loss of TrkA/VEGFR2 Cells, and VEGF Isoform Dysregulation in the Retina of Adult Diabetic Rats.

Published in:

Cells (2073-4409), 2022, v. 11, n. 20, p. 3246, doi. 10.3390/cells11203246

By:

Fico, Elena;
Rosso, Pamela;
Triaca, Viviana;
Segatto, Marco;
Lambiase, Alessandro;
Tirassa, Paola

Publication type:

Article

Neuroglobin: A New Possible Marker of Estrogen-Responsive Breast Cancer.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 1986, doi. 10.3390/cells10081986

By:

Solar Fernandez, Virginia;
Fiocchetti, Marco;
Cipolletti, Manuela;
Segatto, Marco;
Cercola, Paolo;
Massari, Annalisa;
Ghinassi, Sabrina;
Cavaliere, Francesco;
Marino, Maria

Publication type:

Article

ProNGF/p75NTR Axis Drives Fiber Type Specification by Inducing the Fast-Glycolytic Phenotype in Mouse Skeletal Muscle Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2232, doi. 10.3390/cells9102232

By:

Pallottini, Valentina;
Colardo, Mayra;
Tonini, Claudia;
Martella, Noemi;
Strimpakos, Georgios;
Colella, Barbara;
Tirassa, Paola;
Bartolomeo, Sabrina Di;
Segatto, Marco

Publication type:

Article

Evaluation of IL8 pathway on the ocular surface: new insights in patients with ocular mucous membrane pemphigoid.

Published in:

Acta Ophthalmologica (1755375X), 2020, v. 98, n. 2, p. e173, doi. 10.1111/aos.14240

By:

Bruscolini, Alice;
Lambiase, Alessandro;
Segatto, Marco;
La Cava, Maurizio;
Nebbioso, Marcella;
Sacchetti, Marta

Publication type:

Article

Branched‐Chain Amino Acids and Di‐Alanine Supplementation Attenuates Muscle Atrophy in a Murine Model of Cancer Cachexia.

Published in:

Acta Physiologica, 2025, v. 241, n. 7, p. 1, doi. 10.1111/apha.70067

By:

Colardo, Mayra;
Martella, Noemi;
Varone, Michela;
Pensabene, Daniele;
Caretti, Giuseppina;
Bianchini, Gianluca;
Aramini, Andrea;
Segatto, Marco

Publication type:

Article

Impact of Sex and Age on the Mevalonate Pathway in the Brain: A Focus on Effects Induced by Maternal Exposure to Exogenous Compounds.

Published in:

Metabolites (2218-1989), 2020, v. 10, n. 8, p. 304, doi. 10.3390/metabo10080304

By:

Tonini, Claudia;
Segatto, Marco;
Pallottini, Valentina

Publication type:

Article

Analysis of the protein network of cholesterol homeostasis maintenance in a mouse model of Alzheimer's disease.

Published in:

2013

By:

Segatto, Marco;
Rosso, Pamela;
Moreno, Sandra;
Pallottini, Valentina

Publication type:

Abstract

Altered expression of antioxidant enzymes and autophagic proteins in transglutaminase 2 knockout mice.

Published in:

2013

By:

D'Orio, Barbara;
Barone, Luana;
Fracassi, Anna;
Fanelli, Francesca;
Sepe, Sara;
Segatto, Marco;
Piacentini, Mauro;
Nardacci, Roberta;
Moreno, Sandra

Publication type:

Abstract

Psycho-Cognitive Profile and NGF and BDNF Levels in Tears and Serum: A Pilot Study in Patients with Graves' Disease.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 8074, doi. 10.3390/ijms24098074

By:

Bruscolini, Alice;
Iannitelli, Angela;
Segatto, Marco;
Rosso, Pamela;
Fico, Elena;
Buonfiglio, Marzia;
Lambiase, Alessandro;
Tirassa, Paola

Publication type:

Article

Bromodomain and Extraterminal Domain (BET) Protein Inhibition Hinders Glioblastoma Progression by Inducing Autophagy-Dependent Differentiation.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7017, doi. 10.3390/ijms24087017

By:

Colardo, Mayra;
Gargano, Deborah;
Russo, Miriam;
Petraroia, Michele;
Pensabene, Daniele;
D'Alessandro, Giuseppina;
Santoro, Antonio;
Limatola, Cristina;
Segatto, Marco;
Di Bartolomeo, Sabrina

Publication type:

Article

Regulation of Cell Plasticity by Bromodomain and Extraterminal Domain (BET) Proteins: A New Perspective in Glioblastoma Therapy.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5665, doi. 10.3390/ijms24065665

By:

Gargano, Deborah;
Segatto, Marco;
Di Bartolomeo, Sabrina

Publication type:

Article

Beta-Amyloid Peptide in Tears: An Early Diagnostic Marker of Alzheimer's Disease Correlated with Choroidal Thickness.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2590, doi. 10.3390/ijms24032590

By:

Gharbiya, Magda;
Visioli, Giacomo;
Trebbastoni, Alessandro;
Albanese, Giuseppe Maria;
Colardo, Mayra;
D'Antonio, Fabrizia;
Segatto, Marco;
Lambiase, Alessandro

Publication type:

Article

Mechanism Underlying Naringenin Hypocholesterolemic Effects: Involvement of Estrogen Receptor α Subtype.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15809, doi. 10.3390/ijms232415809

By:

Pallottini, Valentina;
Segatto, Marco;
Acconcia, Filippo;
Fiocchetti, Marco;
Marino, Maria

Publication type:

Article

Fat Checking: Emerging Role of Lipids in Metabolism and Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13842, doi. 10.3390/ijms232213842

By:

Segatto, Marco;
Cutone, Antimo;
Pallottini, Valentina

Publication type:

Article

Special Issue "Tumors of the Nervous System: New Insights into Signaling, Genetics and Therapeutic Targeting".

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8700, doi. 10.3390/ijms23158700

By:

Di Bartolomeo, Sabrina;
Segatto, Marco

Publication type:

Article

NGF Modulates Cholesterol Metabolism and Stimulates ApoE Secretion in Glial Cells Conferring Neuroprotection against Oxidative Stress.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4842, doi. 10.3390/ijms23094842

By:

Colardo, Mayra;
Petraroia, Michele;
Lerza, Letizia;
Pensabene, Daniele;
Martella, Noemi;
Pallottini, Valentina;
Segatto, Marco

Publication type:

Article

Neurotrophins as Key Regulators of Cell Metabolism: Implications for Cholesterol Homeostasis.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5692, doi. 10.3390/ijms22115692

By:

Colardo, Mayra;
Martella, Noemi;
Pensabene, Daniele;
Siteni, Silvia;
Di Bartolomeo, Sabrina;
Pallottini, Valentina;
Segatto, Marco

Publication type:

Article

Liver Lipids of Patients with Hepatitis B and C and Associated Hepatocellular Carcinoma.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5297, doi. 10.3390/ijms22105297

By:

Haberl, Elisabeth M.;
Weiss, Thomas S.;
Peschel, Georg;
Weigand, Kilian;
Köhler, Nikolai;
Pauling, Josch K.;
Wenzel, Jürgen J.;
Höring, Marcus;
Krautbauer, Sabrina;
Liebisch, Gerhard;
Buechler, Christa;
Pallottini, Valentina;
Cutone, Antimo;
Segatto, Marco

Publication type:

Article

Epigenetic-Based Therapy—A Prospective Chance for Medulloblastoma Patients' Recovery.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4925, doi. 10.3390/ijms22094925

By:

Strejczek, Agata;
Woszczyk, Dawid;
Urbaniak, Helena;
Różańska, Martyna;
Robak, Michał;
Matuszewska, Zofia;
Barciszewska, Anna-Maria;
Di Bartolomeo, Sabrina;
Segatto, Marco

Publication type:

Article

Targeting RTK-PI3K-mTOR Axis in Gliomas: An Update.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4899, doi. 10.3390/ijms22094899

By:

Colardo, Mayra;
Segatto, Marco;
Di Bartolomeo, Sabrina;
Lombardi, Giuseppe

Publication type:

Article

Challenging Hurdles of Current Targeting in Glioblastoma: A Focus on Immunotherapeutic Strategies.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3493, doi. 10.3390/ijms22073493

By:

Genoud, Vassilis;
Migliorini, Denis;
Di Bartolomeo, Sabrina;
Segatto, Marco

Publication type:

Article

Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy.

Published in:

2020

By:

Segatto, Marco;
Pallottini, Valentina

Publication type:

Editorial

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins by JQ1 Unravels a Novel Epigenetic Modulation to Control Lipid Homeostasis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1297, doi. 10.3390/ijms21041297

By:

Tonini, Claudia;
Colardo, Mayra;
Colella, Barbara;
Di Bartolomeo, Sabrina;
Berardinelli, Francesco;
Caretti, Giuseppina;
Pallottini, Valentina;
Segatto, Marco

Publication type:

Article

Loss of Mevalonate/Cholesterol Homeostasis in the Brain: A Focus on Autism Spectrum Disorder and Rett Syndrome.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 13, p. 3317, doi. 10.3390/ijms20133317

By:

Segatto, Marco;
Tonini, Claudia;
Pfrieger, Frank W.;
Trezza, Viviana;
Pallottini, Valentina

Publication type:

Article

Advancing Biological Research: New Automated Analysis of Immunofluorescence Signals.

Published in:

Applied Sciences (2076-3417), 2024, v. 14, n. 7, p. 2809, doi. 10.3390/app14072809

By:

Salzano, Francesco;
Martella, Noemi;
Pareschi, Remo;
Segatto, Marco

Publication type:

Article

Changes of NGF pathway in allergic rhinoconjunctivitis: A conjunctival allergen challenge study.

Published in:

Allergy, 2019, v. 74, n. 3, p. 605, doi. 10.1111/all.13641

By:

Sacchetti, Marta;
Segatto, Marco;
Bruscolini, Alice;
Abicca, Irene;
Cavaliere, Carlo;
Lambiase, Alessandro

Publication type:

Article

Simvastatin Treatment Highlights a New Role for the Isoprenoid/Cholesterol Biosynthetic Pathway in the Modulation of Emotional Reactivity and Cognitive Performance in Rats.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 4, p. 841, doi. 10.1038/npp.2013.284

By:

Segatto, Marco;
Manduca, Antonia;
Lecis, Claudio;
Rosso, Pamela;
Jozwiak, Adam;
Swiezewska, Ewa;
Moreno, Sandra;
Trezza, Viviana;
Pallottini, Valentina

Publication type:

Article

Chemical Profiling of Polyphenolic Fraction of Cannabis sativa L. vr. Kompolti Industrial Inflorescences: Insights into Cannabidiol Neuroprotective Effects in a Cellular Model of Parkinson's Disease.

Published in:

Plants (2223-7747), 2025, v. 14, n. 10, p. 1473, doi. 10.3390/plants14101473

By:

Fantasma, Francesca;
D'Urso, Gilda;
Martella, Noemi;
Capuano, Alessandra;
Boccia, Eleonora;
Samukha, Vadym;
De Felice, Vincenzo;
Saviano, Gabriella;
Trombetta, Federico;
Lauro, Gianluigi;
Segatto, Marco;
Chini, Maria Giovanna;
Bifulco, Giuseppe;
Casapullo, Agostino;
Iorizzi, Maria

Publication type:

Article

Vernal keratoconjunctivitis activity induces decrease of ocular surface CD14, TLR-4 and TLR-9 expression.

Published in:

European Journal of Ophthalmology, 2022, v. 32, n. 4, p. 2274, doi. 10.1177/11206721211048814

By:

Sacchetti, Marta;
Nebbioso, Marcella;
Segatto, Marco;
Abicca, Irene;
Bruscolini, Alice;
Zicari, Anna Maria;
Lambiase, Alessandro

Publication type:

Article

Unidirectional opioid-cannabinoid cross-tolerance in the modulation of social play behavior in rats.

Published in:

Psychopharmacology, 2019, v. 236, n. 9, p. 2557, doi. 10.1007/s00213-019-05226-y

By:

Schiavi, Sara;
Manduca, Antonia;
Segatto, Marco;
Campolongo, Patrizia;
Pallottini, Valentina;
Vanderschuren, Louk J. M. J.;
Trezza, Viviana

Publication type:

Article

ATP Sensitive Potassium Channels in the Skeletal Muscle Function: Involvement of the KCNJ11(Kir6.2) Gene in the Determination of Mechanical Warner Bratzer Shear Force.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00167

By:

Tricarico, Domenico;
Selvaggi, Maria;
Passantino, Giuseppe;
De Palo, Pasquale;
Dario, Cataldo;
Centoducati, Pasquale;
Tateo, Alessandra;
Curci, Angela;
Maqoud, Fatima;
Mele, Antonietta;
Camerino, Giulia M.;
Liantonio, Antonella;
Imbrici, Paola;
Zizzo, Nicola;
Singh, Harpreet;
Velisetty, Phanindra;
Segatto, Marco

Publication type:

Article

Extracellular Neuroglobin as a Stress-Induced Factor Activating Pre-Adaptation Mechanisms against Oxidative Stress and Chemotherapy-Induced Cell Death in Breast Cancer.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2451, doi. 10.3390/cancers12092451

By:

Fiocchetti, Marco;
Solar Fernandez, Virginia;
Segatto, Marco;
Leone, Stefano;
Cercola, Paolo;
Massari, Annalisa;
Cavaliere, Francesco;
Marino, Maria

Publication type:

Article

mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells.

Published in:

Cancers, 2020, v. 12, n. 8, p. 2266, doi. 10.3390/cancers12082266

By:

Colella, Barbara;
Colardo, Mayra;
Iannone, Gianna;
Contadini, Claudia;
Saiz-Ladera, Cristina;
Fuoco, Claudia;
Barilà, Daniela;
Velasco, Guillermo;
Segatto, Marco;
Di Bartolomeo, Sabrina

Publication type:

Article

Regulation of cholesterol metabolism: New players for an old physiological process.

Published in:

Journal of Cellular Biochemistry, 2023, v. 124, n. 10, p. 1449, doi. 10.1002/jcb.30477

By:

Parente, Martina;
Tonini, Claudia;
Segatto, Marco;
Pallottini, Valentina

Publication type:

Article

Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro.

Published in:

Journal of Cellular Biochemistry, 2016, v. 117, n. 9, p. 2036, doi. 10.1002/jcb.25500

By:

Cartocci, Veronica;
Segatto, Marco;
Di Tunno, Ilenia;
Leone, Stefano;
Pfrieger, Frank W.;
Pallottini, Valentina

Publication type:

Article

3-hydroxy 3-methylglutaryl coenzyme a reductase inhibition impairs muscle regeneration.

Published in:

Journal of Cellular Biochemistry, 2012, v. 113, n. 6, p. 2057, doi. 10.1002/jcb.24077

By:

Trapani, Laura;
Segatto, Marco;
La Rosa, Piergiorgio;
Fanelli, Francesca;
Moreno, Sandra;
Marino, Maria;
Pallottini, Valentina

Publication type:

Article

Prenatal Exposure to BPA: The Effects on Hepatic Lipid Metabolism in Male and Female Rat Fetuses.

Published in:

Nutrients, 2021, v. 13, n. 6, p. 1970, doi. 10.3390/nu13061970

By:

Tonini, Claudia;
Segatto, Marco;
Bertoli, Simona;
Leone, Alessandro;
Mazzoli, Arianna;
Cigliano, Luisa;
Barberio, Laura;
Mandalà, Maurizio;
Pallottini, Valentina

Publication type:

Article

Effects of Late-Life Caloric Restriction on Age-Related Alterations in the Rat Cortex and Hippocampus.

Published in:

Nutrients, 2021, v. 13, n. 1, p. 232, doi. 10.3390/nu13010232

By:

Tonini, Claudia;
Segatto, Marco;
Martino, Francesca;
Cigliano, Luisa;
Nazzaro, Martina;
Barberio, Laura;
Mandalà, Maurizio;
Pallottini, Valentina

Publication type:

Article

Maternal Dietary Exposure to Low-Dose Bisphenol A Affects Metabolic and Signaling Pathways in the Brain of Rat Fetuses.

Published in:

Nutrients, 2020, v. 12, n. 5, p. 1448, doi. 10.3390/nu12051448

By:

Tonini, Claudia;
Segatto, Marco;
Gagliardi, Simone;
Bertoli, Simona;
Leone, Alessandro;
Barberio, Laura;
Mandalà, Maurizio;
Pallottini, Valentina

Publication type:

Article

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01645-7

By:

Segatto, Marco;
Fittipaldi, Raffaella;
Fenizia, Claudio;
Caretti, Giuseppina;
Pin, Fabrizio;
Costelli, Paola;
Sartori, Roberta;
Sandri, Marco;
Kyung Dae Ko;
Zare, Hossein;
Sartorelli, Vittorio;
Zanchettin, Gianpietro;
Pierobon, Elisa Sefora;
Sperti, Cosimo;
Merigliano, Stefano;
Shinji Hatakeyama;
Filippakopoulos, Panagis

Publication type:

Article

Building the Resilience of Marginal Rural Areas Using a Complementary Characterization Approach: Possible Beneficial Health Effects and Stress Tolerance of Italian Common Bean (Phaseolus vulgaris L.) Landraces.

Published in:

Diversity (14242818), 2024, v. 16, n. 4, p. 240, doi. 10.3390/d16040240

By:

Falcione, Martina;
Renella, Alessandra;
Samukha, Vadym;
Colardo, Mayra;
Simiele, Melissa;
Scippa, Gabriella Stefania;
Segatto, Marco;
Trupiano, Dalila

Publication type:

Article

Interaction and compatibility studies of efavirenz with pharmaceutical excipients.

Published in:

Journal of Excipients & Food Chemicals, 2014, v. 5, n. 3, p. 152

By:

Fandaruff, Cinira;
Araya-Sibaja, Andrea Mariela;
Pereira, Rafael Nicolay;
Cuffini, Silvia Lucia;
Maduro de Campos, Carlos Eduardo;
Rodrigues Drago Hoffmeister, Cristiane;
Antunes Rocha, Helvécio Vinícius;
Segatto Silva, Marco Antônio

Publication type:

Article

Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions.

Published in:

FASEB Journal, 2011, v. 25, n. 11, p. 4037, doi. 10.1096/fj.11-184218

By:

Trapani, Laura;
Melli, Luca;
Segatto, Marco;
Trezza, Viviana;
Campolongo, Patrizia;
Jozwiak, Adam;
Swiezewska, Ewa;
Pucillo, Leopoldo Paolo;
Moreno, Sandra;
Fanelli, Francesca;
Linari, Marco;
Pallottini, Valentina

Publication type:

Article

VEGF inhibition alters neurotrophin signalling pathways and induces caspase‐3 activation and autophagy in rabbit retina.

Published in:

Journal of Cellular Physiology, 2019, v. 234, n. 10, p. 18297, doi. 10.1002/jcp.28462

By:

Segatto, Marco;
Fico, Elena;
Gharbiya, Magda;
Rosso, Pamela;
Carito, Valentina;
Tirassa, Paola;
Plateroti, Rocco;
Lambiase, Alessandro

Publication type:

Article

In vivo antivascular endothelial growth factor treatment induces corneal endothelium apoptosis in rabbits through changes in p75NTR–proNGF pathway.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 11, p. 8874, doi. 10.1002/jcp.26806

By:

Gharbiya, Magda;
Bruscolini, Alice;
Sacchetti, Marta;
Rosso, Pamela;
Carito, Valentina;
Segatto, Marco;
Fico, Elena;
Tirassa, Paola;
Lambiase, Alessandro

Publication type:

Article

BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19839-x

By:

Segatto, Marco;
Szokoll, Roberta;
Fittipaldi, Raffaella;
Bottino, Cinzia;
Nevi, Lorenzo;
Mamchaoui, Kamel;
Filippakopoulos, Panagis;
Caretti, Giuseppina

Publication type:

Article