Works matching AU Sebti, Said

Results: 70

Targeting protein prenylation for cancer therapy.

Published in:

2011

By:

Berndt, Norbert;
Hamilton, Andrew D.;
Sebti, Saïd M.;
Sebti, Saïd M

Publication type:

journal article

Structurally Simple Farnesyltransferase Inhibitors Arrest the Growth of Malaria ParasitesThis work was supported by the Medicines for Malaria Venture (MMV) and NIH grants CA67771 and AI054384. S.-Y.C. thanks the Postdoctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF). O.H. gratefully acknowledges a postdoctoral fellowship of the German Academy of Natural Scientists Leopoldina (BMBF-LPD 9901/8-77). We thank David Floyd, Lou Lombardo and David Williams from Bristol-Myers Squibb for helpful suggestions.

Published in:

Angewandte Chemie, 2005, v. 117, n. 31, p. 4981, doi. 10.1002/ange.200500674

By:

Matthew P. Glenn;
Sung-Youn Chang;
Oliver Hucke;
Christophe L. M. J. Verlinde;
Kasey Rivas;
Carrie Hornéy;
Kohei Yokoyama;
Frederick S. Buckner;
Prakash R. Pendyala;
Debopam Chakrabarti;
Michael Gelb;
Wesley C. Van Voorhis;
Saïd M. Sebti;
Andrew D. Hamilton

Publication type:

Article

Terphenyl-Based Helical Mimetics That Disrupt the p53/HDM2 InteractionWe thank the National Institutes of Health for support of this work (GM35208 and GM69850). The HDM2 pQE40 construct was kindly provided by Dr. Christian Klein (Hoffmann-La Roche, Inc.).

Published in:

Angewandte Chemie, 2005, v. 117, n. 18, p. 2764, doi. 10.1002/ange.200462316

By:

Hang Yin;
Gui-in Lee;
Hyung Soon Park;
Gregory A. Payne;
Johanna M. Rodriguez;
Said M. Sebti;
Andrew D. Hamilton

Publication type:

Article

Desensitization of 5HT2 Receptors by Protein Kinase C Activation in Distal Pulmonary Vascular Smooth Muscle Cells in Culture.

Published in:

Microcirculation, 1994, v. 1, n. 2, p. 129, doi. 10.3109/10739689409148268

By:

Weng, Weili;
Reynolds, Ian J.;
Jani, Jitesh P.;
Blaskovich, Michelle;
Sebti, Said M.;
Davies, Paul;
Pitt, Bruce R.

Publication type:

Article

Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice.

Published in:

Nature Biotechnology, 2000, v. 18, n. 10, p. 1065, doi. 10.1038/80257

By:

Blaskovich, Michelle A.;
Lin, Qing;
Delarue, Frederic L.;
Sun, Jiazhi;
Park, Hyung Soon;
Coppola, Domenico;
Hamilton, Andrew D.;
Sebti, Saïd M.

Publication type:

Article

Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis.

Published in:

Cell Cycle, 2013, v. 12, n. 13, p. 2024, doi. 10.4161/cc.25043

By:

Berndt, Norbert;
Patel, Ronil;
Hua Yang;
Balasis, Maria E.;
Sebti, Saïd M.

Publication type:

Article

Depletion of K-Ras promotes proteasome degradation of survivin.

Published in:

Cell Cycle, 2013, v. 12, n. 3, p. 521, doi. 10.4161/cc.23407

By:

Tecleab, Awet;
Sebti, Saïd M.

Publication type:

Article

Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.

Published in:

Cell Cycle, 2012, v. 11, n. 17, p. 3250, doi. 10.4161/cc.21611

By:

Ucar, Deniz A.;
Kurenova, Elena;
Garrett, Timothy J.;
Cance, William G.;
Nyberg, Carl;
Cox, Audrey;
Massoll, Nicole;
Ostrov, David A.;
Lawrence, Nicholas;
Sebti, Said M.;
Zajac-Kaye, Maria;
Hochwald, Steven N.

Publication type:

Article

Porphyrin overdrive rewires cancer cell metabolism.

Published in:

Life Science Alliance, 2024, v. 7, n. 7, p. 1, doi. 10.26508/lsa.202302547

By:

Adapa, Swamy R.;
Hunter, Gregory A.;
Amin, Narmin E.;
Marinescu, Christopher;
Borsky, Andrew;
Sagatys, Elizabeth M.;
Sebti, Said M.;
Reuther, Gary W.;
Ferreira, Gloria C.;
Jiang, Rays H. Y.

Publication type:

Article

Natural Phosphate Modified with Lithium Nitrate: A New Efficient Catalyst for the Construction of Carbon-Carbon, Carbon-Sulfur, and Carbon-Nitrogen Bonds.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2007, v. 182, n. 6, p. 1203, doi. 10.1080/10426500601160397

By:

Zahouily, Mohamed;
Mounir, Bahija;
Cherki, Hind;
Bahlaouan, Bouchaib;
Rayadh, Ahmed;
Sebti, Saïd

Publication type:

Article

Design and Evaluation of Bivalent K‐Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 27, p. 1, doi. 10.1002/chem.202500306

By:

Horiuchi, Naomi;
Omer, Rania;
Sugino, Fumitoshi;
Ogino, Nanami;
Inoue, Yoshihisa;
Aslamuzzaman, Kazi;
Suzuki, Takeyuki;
Sebti, Said M.;
Ohkanda, Junko

Publication type:

Article

One-Pot Synthesis of Antiviral Acyclovir and Other Nucleosides Derivatives Using Doped Natural Phosphate as Lewis Acid Catalyst.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2008, v. 27, n. 10/11, p. 1107, doi. 10.1080/15257770802341285

By:

Lazrek, HassanB.;
Baddi, Laila;
Smietana, Michael;
Vasseur, Jean-Jacques;
Sebti, Saïd;
Zahouily, Mohamed

Publication type:

Article

A Phase I Study of GGTI-2418 (Geranylgeranyl Transferase I Inhibitor) in Patients with Advanced Solid Tumors.

Published in:

Targeted Oncology, 2019, v. 14, n. 5, p. 613, doi. 10.1007/s11523-019-00661-5

By:

Karasic, Thomas B.;
Chiorean, E. Gabriela;
Sebti, Said M.;
O'Dwyer, Peter J.

Publication type:

Article

A Phase I Study of GGTI-2418 (Geranylgeranyl Transferase I Inhibitor) in Patients with Advanced Solid Tumors.

Published in:

2019

By:

Karasic, Thomas B;
Chiorean, E Gabriela;
Sebti, Said M;
O'Dwyer, Peter J

Publication type:

journal article

Protein farnesyltransferase: Flexible docking studies on inhibitors using computational modeling.

Published in:

Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 12, p. 871, doi. 10.1007/s10822-005-9030-2

By:

Guida, Wayne;
Hamilton, Andrew;
Crotty, Justin;
Sebti, Saïd

Publication type:

Article

Farnesyltransferase as a target for anticancer drug design.

Published in:

Biopolymers, 1997, v. 43, n. 1, p. 25, doi. 10.1002/(SICI)1097-0282(1997)43:1<25::AID-BIP4>3.0.CO;2-2

By:

Qian, Yimin;
Sebti, Saïd M.;
Hamilton, Andrew D.

Publication type:

Article

Synthesis of organophosphates starting from α-hydroxyphosphonates.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2019, v. 194, n. 4-6, p. 370, doi. 10.1080/10426507.2018.1547722

By:

Kiss, Nóra Z.;
Rádai, Zita;
Szabó, Réka;
Aichi, Youness;
Laasri, Laila;
Sebti, Said

Publication type:

Article

Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.

Published in:

Science Translational Medicine, 2017, v. 9, n. 372, p. 1, doi. 10.1126/scitranslmed.aai8269

By:

Betts, Brian C.;
Veerapathran, Anandharaman;
Pidala, Joseph;
Hua Yang;
Horna, Pedro;
Walton, Kelly;
Cubitt, Christopher L.;
Gunawan, Steven;
Lawrence, Harshani R.;
Lawrence, Nicholas J.;
Sebti, Said M.;
Anasetti, Claudio

Publication type:

Article

MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines.

Published in:

Cancer Biology & Therapy, 2013, v. 14, n. 10, p. 932, doi. 10.4161/cbt.25939

By:

Almhanna, Khaldoun;
Cubitt, Christopher L.;
Zhang, Shumin;
Kazim, Sabiha;
Husain, Kazim;
Sullivan, Dan;
Sebti, Said;
Malafa, Mokenge

Publication type:

Article

Protein Geranylgeranylation Is Required for Osteoclast Formation, Function, and Survival: Inhibition by Bisphosphonates and GGTI-298.

Published in:

Journal of Bone & Mineral Research, 2000, v. 15, n. 8, p. 1467, doi. 10.1359/jbmr.2000.15.8.1467

By:

Coxon, Fraser P.;
Helfrich, Miep H.;
Van't Hof, Robert;
Sebti, Saïd;
Ralston, Stuart H.;
Hamilton, Andrew;
Rogers, Michael J.

Publication type:

Article

MODELING AND OPTIMIZATION FOR PRODUCTION OF STAINLESS STEEL CORROSION INHIBITORS FORMULATED WITH 1,3-DIPHENYL-3-PHENYLSULFANYL-PROPAN-1-ONE: A CLEAN PROCESS CATALYSED BY FLUORAPATITE.

Published in:

Journal of Engineering Studies & Research, 2013, v. 19, n. 4, p. 89

By:

YOUNES, ABROUKI;
ABDELKADER, ANOUZLA;
HAYAT, LOUKILI;
RABIAÂ, LOTFI;
AHMED, RAYADH;
ABDELLAH, BAHLAOUI MY;
HASSAN, CHAAIR;
SAID, SEBTI;
DRISS, ZAKARYA;
MOHAMED, ZAHOUILY

Publication type:

Article

Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.

Published in:

Oncogene, 1998, v. 16, n. 11, p. 1467, doi. 10.1038/sj.onc.1201656

By:

Sun, Jiazhi;
Qian, Yimin;
Hamilton, Andrew D;
Sebti, Saïd M

Publication type:

Article

Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.

Published in:

Oncogene, 1997, v. 15, n. 11, p. 1283, doi. 10.1038/sj.onc.1201296

By:

Lerner, Edwina C;
Zhang, Ting-Ting;
Knowles, David B;
Qian, Yimin;
Hamilton, Andrew D;
Sebti, Saïd M

Publication type:

Article

Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity.

Published in:

Oncogene, 1997, v. 14, n. 3, p. 305, doi. 10.1038/sj.onc.1200819

By:

McGuire, Terence F;
Sebti, Saïd M

Publication type:

Article

TNFα-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes.

Published in:

Cell Cycle, 2012, v. 11, n. 1, p. 109, doi. 10.4161/cc.11.1.18473

By:

Davis, Rebecca;
Pillai, Smitha;
Lawrence, Nicholas;
Sebti, Said;
Chellappan, Srikumar P.

Publication type:

Article

Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells.

Published in:

Cell Cycle, 2009, v. 8, n. 12, p. 1940, doi. 10.4161/cc.8.12.8798

By:

Kazi, Aslamuzzaman;
Lawrence, Harshani;
Guida, Wayne C.;
McLaughlin, Mark L.;
Springett, Gregory M.;
Berndt, Norbert;
Yip, Richard M. L.;
Sebti, Saïd M.

Publication type:

Article

Farnesylated RhoB Prevents Cell Cycle Arrest and Actin Cytoskeleton Disruption Caused by the Geranylgeranyltransferase I Inhibitor GGTI-298.

Published in:

Cell Cycle, 2002, v. 1, n. 6, p. 430, doi. 10.4161/cc.1.6.272

By:

Allal, Cuider;
Pradines, Anne;
Hamilton, Andrew D.;
Sebti, Said M.;
Favre, Gilles

Publication type:

Article

Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27Kip1 Phosphorylation on Thr187 and Accumulates p27Kip1 in the Nucleus: Implications for Breast Cancer Therapy.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 8, p. 2254, doi. 10.1128/MCB.01029-08

By:

Kazi, Aslamuzzaman;
Carie, Adam;
Blaskovich, Michelle A.;
Bucher, Cynthia;
Thai, Van;
Moulder, Stacy;
Hairuo Peng;
Carrico, Dora;
Pusateri, Erin;
Pledger, Warren J.;
Berndt, Norbert;
Hamilton, Andrew;
Sebti, Saïd M.

Publication type:

Article

Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent Growth.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 22, p. 23, doi. 10.1128/MCB.00057-07

By:

Falsetti, Samuel C.;
De-an Wang;
Hairuo Peng;
Carrico, Dora;
Cox, Adrienne D.;
Der, Channing J.;
Hamilton, Andrew D.;
Sebti, Saíd M.

Publication type:

Article

Targeting Protein-Protein Interactions: Suppression of Stat3 Dimerization with Rationally Designed Small-Molecule, Nonpeptidic SH2 Domain Binders.

Published in:

ChemBioChem, 2008, v. 9, n. 17, p. 2800, doi. 10.1002/cbic.200800291

By:

Gunning, Patrick T.;
Glenn, Matthew P.;
Siddiquee, Khandaker A. Z.;
Katt, William P.;
Masson, Eric;
Sebti, Saïd M.;
Turkson, James;
Hamilton, Andrew D.

Publication type:

Article

Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.

Published in:

Investigational New Drugs, 2011, v. 29, n. 6, p. 1381, doi. 10.1007/s10637-010-9479-2

By:

Garrett, Christopher;
Coppola, Domenico;
Wenham, Robert;
Cubitt, Christopher;
Neuger, Anthony;
Frost, Timothy;
Lush, Richard;
Sullivan, Daniel;
Cheng, Jin;
Sebti, Saïd

Publication type:

Article

Tipifarnib-mediated suppression of T-bet-dependent signaling pathways.

Published in:

Cancer Immunology, Immunotherapy, 2012, v. 61, n. 4, p. 523, doi. 10.1007/s00262-011-1109-0

By:

Bai, Fanqi;
Villagra, Alejandro;
Zou, JianXiang;
Painter, Jeffrey;
Connolly, Kirby;
Blaskovich, Michelle;
Sokol, Lubomir;
Sebti, Said;
Djeu, Julie;
Loughran, Thomas;
Wei, Sheng;
Sotomayor, Eduardo;
Epling-Burnette, Pearlie

Publication type:

Article

Vitamin E δ-Tocotrienol Levels in Tumor and Pancreatic Tissue of Mice after Oral Administration.

Published in:

Pharmacology, 2009, v. 83, n. 3, p. 157, doi. 10.1159/000190792

By:

Husain, Kazim;
Francois, Rony A.;
Hutchinson, Sean Z.;
Neuger, Anthony M.;
Lush, Richard;
Coppola, Domenico;
Sebti, Said;
Malafa, Mokenge P.

Publication type:

Article

Searching for the elusive targets of farnesyltransferase inhibitors.

Published in:

Nature Reviews Cancer, 2003, v. 3, n. 12, p. 945, doi. 10.1038/nrc1234

By:

Sebti, Saïd M.;
Der, Channing J.

Publication type:

Article

Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Published in:

Carcinogenesis, 2000, v. 21, n. 1, p. 113, doi. 10.1093/carcin/21.1.113

By:

Lantry, Laura E.;
Zhang, Zhongqiu;
Yao, Rusheng;
Crist, Keith A.;
Wang, Yian;
Ohkanda, Junko;
Hamilton, Andrew D.;
Sebti, Said M.;
lubet, Ronald A.;
You, Ming

Publication type:

Article

HPP1-mediated tumor suppression requires activation of STAT1 pathways.

Published in:

International Journal of Cancer, 2008, v. 122, n. 7, p. 1567, doi. 10.1002/ijc.23202

By:

Elahi, Abul;
Zhang, Li;
Yeatman, Timothy J.;
Gery, Sigal;
Sebti, Said;
Shibata, David

Publication type:

Article

Structurally Simple Farnesyltransferase Inhibitors Arrest the Growth of Malaria ParasitesThis work was supported by the Medicines for Malaria Venture (MMV) and NIH grants CA67771 and AI054384. S.-Y.C. thanks the Postdoctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF). O.H. gratefully acknowledges a postdoctoral fellowship of the German Academy of Natural Scientists Leopoldina (BMBF-LPD 9901/8-77). We thank David Floyd, Lou Lombardo and David Williams from Bristol-Myers Squibb for helpful suggestions.

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 31, p. 4903, doi. 10.1002/anie.200500674

By:

Matthew P. Glenn;
Sung-Youn Chang;
Oliver Hucke;
Christophe L. M. J. Verlinde;
Kasey Rivas;
Carrie Hornéy;
Kohei Yokoyama;
Frederick S. Buckner;
Prakash R. Pendyala;
Debopam Chakrabarti;
Michael Gelb;
Wesley C. Van Voorhis;
Saïd M. Sebti;
Andrew D. Hamilton

Publication type:

Article

Terphenyl-Based Helical Mimetics That Disrupt the p53/HDM2 InteractionWe thank the National Institutes of Health for support of this work (GM35208 and GM69850). The HDM2 pQE40 construct was kindly provided by Dr. Christian Klein (Hoffmann-La Roche, Inc.).

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 18, p. 2704, doi. 10.1002/anie.200462316

By:

Hang Yin;
Gui-in Lee;
Hyung Soon Park;
Gregory A. Payne;
Johanna M. Rodriguez;
Said M. Sebti;
Andrew D. Hamilton

Publication type:

Article

p-Toluenesulfonic acid coated natural phosphate as an efficient catalyst for the synthesis of 2-substituted benzimidazole.

Published in:

Journal of Chemical Research, 2018, v. 42, n. 12, p. 614, doi. 10.3184/174751918X15420201703363

By:

Belkharchach, Soumia;
Elayadia, Hanane;
Ighachane, Hana;
Sebti, Said;
Ali, Mustapha Ait;
Lazrek, Hassan B.

Publication type:

Article

Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.

Published in:

Oncogene, 2003, v. 22, n. 40, p. 6257, doi. 10.1038/sj.onc.1206630

By:

Zhongqiu Zhang;
Yian Wang;
Lantry, Laura E.;
Kastens, Elizabeth;
Gongjie Liu;
D. Hamilton, Andrew;
Sebti, Said M.;
Lubet, Ronald A.;
Ming You

Publication type:

Article

Rescue of mutant p53 transcription function by ellipticine.

Published in:

Oncogene, 2003, v. 22, n. 29, p. 4478, doi. 10.1038/sj.onc.1206777

By:

Peng, Yanhua;
Li, Changgong;
Chen, Lihong;
Sebti, Said;
Chen, Jiandong

Publication type:

Article

Loss of the cell cycle inhibitors p21Cip1 and p27Kip1 enhances tumorigenesis in knockout mouse models.

Published in:

Oncogene, 2002, v. 21, n. 55, p. 8486, doi. 10.1038/sj.onc.1205946

By:

Jackson, Rosalind J;
Adnane, Jalila;
Coppola, Domenico;
Cantor, Alan;
Sebti, Saïd M;
Pledger, W Jock

Publication type:

Article

Ras and RhoA suppress whereas RhoB enhances cytokine-induced transcription of nitric oxide synthase-2 in human normal liver AKN-1 cells and lung cancer A-549 cells.

Published in:

Oncogene, 2001, v. 20, n. 45, p. 6531, doi. 10.1038/sj.onc.1204801

By:

Delarue, Frederic L;
Taylor, Bradley S;
Sebti, Saïd M

Publication type:

Article

Design of growth factor antagonists with antiangiogenic and antitumor properties.

Published in:

Oncogene, 2000, v. 19, n. 56, p. 6566, doi. 10.1038/sj.onc.1204121

By:

Sebti, Saïd M;
Hamilton, Andrew D

Publication type:

Article

Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: Lessons from mechanism and bench-to-bedside translational studies.

Published in:

Oncogene, 2000, v. 19, n. 56, p. 6584, doi. 10.1038/sj.onc.1204146

By:

Sebti, Saïd M;
Hamilton, Andrew D

Publication type:

Article

Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ.

Published in:

Oncogene, 2000, v. 19, n. 48, p. 5525, doi. 10.1038/sj.onc.1203920

By:

Adnane, Jalila;
Bizouarn, Francisco A;
Chen, Zhi;
Ohkanda, Junko;
Hamilton, Andrew D;
Munoz-Antonia, Teresita;
Sebti, Saïd M

Publication type:

Article

Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model.

Published in:

Oncogene, 2000, v. 19, n. 47, p. 5338, doi. 10.1038/sj.onc.1203956

By:

Adnane, Jalila;
Jackson, Rosalind J;
Nicosia, Santo V;
Cantor, Alan B;
Pledger, W Jack;
Sebti, Saïd M

Publication type:

Article

Lysophosphatidic Acid Acyltransferase Beta Regulates mTOR Signaling.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078632

By:

Blaskovich, Michelle A.;
Yendluri, Vimala;
Lawrence, Harshani R.;
Lawrence, Nicholas J.;
Sebti, Saïd M.;
Springett, Gregory M.

Publication type:

Article

Vitamin E δ-Tocotrienol Induces p27Kip1-Dependent Cell-Cycle Arrest in Pancreatic Cancer Cells via an E2F-1-Dependent Mechanism.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0052526

By:

Hodul, Pamela J.;
Dong, Yanbin;
Husain, Kazim;
Pimiento, Jose M.;
Chen, Jiandong;
Zhang, Anying;
Francois, Rony;
Pledger, Warren J.;
Coppola, Domenico;
Sebti, Said M.;
Chen, Dung-Tsa;
Malafa, Mokenge P.

Publication type:

Article

Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009646

By:

Mahajan, Kiran;
Coppola, Domenico;
Challa, Sridevi;
Bin Fang;
Chen, Y. Ann;
Weiwei Zhu;
Lopez, Alexis S.;
Koomen, John;
Engelman, Robert W.;
Rivera, Charlene;
Muraoka-Cook, Rebecca S.;
Cheng, Jin Q.;
Schönbrunn, Ernst;
Sebti, Said M.;
Earp, H. Shelton;
Mahajan, Nupam P.

Publication type:

Article