Works by Seashore‐Ludlow, Brinton

Results: 18

Delineating functional and molecular impact of ex vivo sample handling in precision medicine.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00528-7

By:

Struyf, Nona;
Österroos, Albin;
Vesterlund, Mattias;
Arnroth, Cornelia;
James, Tojo;
Sunandar, Stephanie;
Mermelekas, Georgios;
Bohlin, Anna;
Hamberg Levedahl, Kerstin;
Bengtzén, Sofia;
Jafari, Rozbeh;
Orre, Lukas M.;
Lehtiö, Janne;
Lehmann, Sören;
Östling, Päivi;
Kallioniemi, Olli;
Seashore-Ludlow, Brinton;
Erkers, Tom

Publication type:

Article

The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00463-z

By:

Åkerlund, Emma;
Gudoityte, Greta;
Moussaud-Lamodière, Elisabeth;
Lind, Olina;
Bwanika, Henri Colyn;
Lehti, Kaisa;
Salehi, Sahar;
Carlson, Joseph;
Wallin, Emelie;
Fernebro, Josefin;
Östling, Päivi;
Kallioniemi, Olli;
Joneborg, Ulrika;
Seashore-Ludlow, Brinton

Publication type:

Article

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54400-6

By:

Bwanika, Henri Colyn;
Leo, Isabelle Rose;
Struyf, Nona;
Talanti, Asimina;
Aswad, Luay;
Konnur, Aishwarya;
Björklund, Ann-Charlotte;
Heyman, Mats;
Rassidakis, Georgios;
Erkers, Tom;
Seashore-Ludlow, Brinton;
Jafari, Rozbeh;
Pokrovskaja Tamm, Katja

Publication type:

Article

PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair.

Published in:

Cancers, 2021, v. 13, n. 14, p. 3604, doi. 10.3390/cancers13143604

By:

Ninou, Anna Huguet;
Lehto, Jemina;
Chioureas, Dimitrios;
Stigsdotter, Hannah;
Schelzig, Korbinian;
Åkerlund, Emma;
Gudoityte, Greta;
Joneborg, Ulrika;
Carlson, Joseph;
Jonkers, Jos;
Seashore-Ludlow, Brinton;
Gustafsson, Nina Marie Susanne

Publication type:

Article

A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03031-w

By:

Fonseca, Pedro;
Cui, Weiyingqi;
Struyf, Nona;
Tong, Le;
Chaurasiya, Ayushi;
Casagrande, Felipe;
Zhao, Honglei;
Fernando, Dinura;
Chen, Xinsong;
Tobin, Nicholas P.;
Seashore-Ludlow, Brinton;
Lundqvist, Andreas;
Hartman, Johan;
Göndör, Anita;
Östling, Päivi;
Holmgren, Lars

Publication type:

Article

High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.

Published in:

Molecular Oncology, 2024, v. 18, n. 2, p. 317, doi. 10.1002/1878-0261.13502

By:

Zaghmi, Ahlem;
Aybay, Erdem;
Jiang, Long;
Shang, Mingmei;
Steinmetz‐Späh, Julia;
Wermeling, Fredrik;
Kogner, Per;
Korotkova, Marina;
Östling, Päivi;
Jakobsson, Per‐Johan;
Seashore‐Ludlow, Brinton;
Larsson, Karin

Publication type:

Article

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

Published in:

Molecular Systems Biology, 2018, v. 14, n. 3, p. 1, doi. 10.15252/msb.20177858

By:

Azimi, Alireza;
Caramuta, Stefano;
Seashore‐Ludlow, Brinton;
Boström, Johan;
Robinson, Jonathan L;
Edfors, Fredrik;
Tuominen, Rainer;
Kemper, Kristel;
Krijgsman, Oscar;
Peeper, Daniel S;
Nielsen, Jens;
Hansson, Johan;
Egyhazi Brage, Suzanne;
Altun, Mikael;
Uhlen, Mathias;
Maddalo, Gianluca

Publication type:

Article

SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.

Published in:

Cell Death & Disease, 2024, v. 15, n. 9, p. 1, doi. 10.1038/s41419-024-07106-6

By:

Murga, Matilde;
Lopez-Pernas, Gema;
Soliva, Robert;
Fueyo-Marcos, Elena;
Amor, Corina;
Faustino, Ignacio;
Serna, Marina;
Serrano, Alicia G.;
Díaz, Lucía;
Martínez, Sonia;
Blanco-Aparicio, Carmen;
Antón, Marta Elena;
Seashore-Ludlow, Brinton;
Pastor, Joaquín;
Jafari, Rozbeh;
Lafarga, Miguel;
Llorca, Oscar;
Orozco, Modesto;
Fernández-Capetillo, Oscar

Publication type:

Article

Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention.

Published in:

Cell Death & Disease, 2022, v. 13, n. 8, p. 1, doi. 10.1038/s41419-022-05161-5

By:

Raivola, Juuli;
Dini, Alice;
Karvonen, Hanna;
Piki, Emilia;
Salokas, Kari;
Niininen, Wilhelmiina;
Kaleva, Laura;
Zhang, Kaiyang;
Arjama, Mariliina;
Gudoityte, Greta;
Seashore-Ludlow, Brinton;
Varjosalo, Markku;
Kallioniemi, Olli;
Hautaniemi, Sampsa;
Murumägi, Astrid;
Ungureanu, Daniela

Publication type:

Article

The transcriptome‐wide landscape of molecular subtype‐specific mRNA expression profiles in acute myeloid leukemia.

Published in:

American Journal of Hematology, 2021, v. 96, n. 5, p. 580, doi. 10.1002/ajh.26141

By:

Mou, Tian;
Pawitan, Yudi;
Stahl, Matthias;
Vesterlund, Mattias;
Deng, Wenjiang;
Jafari, Rozbeh;
Bohlin, Anna;
Österroos, Albin;
Siavelis, Loannis;
Bäckvall, Helena;
Erkers, Tom;
Kiviluoto, Santeri;
Seashore‐Ludlow, Brinton;
Östling, Päivi;
Orre, Lukas M.;
Kallioniemi, Olli;
Lehmann, Sören;
Lehtiö, Janne;
Vu, Trung Nghia

Publication type:

Article

Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07766-w

By:

Sharma, Osheen;
Gudoityte, Greta;
Minozada, Rezan;
Kallioniemi, Olli P.;
Turkki, Riku;
Paavolainen, Lassi;
Seashore-Ludlow, Brinton

Publication type:

Article

Targeting SAMHD1 with hydroxyurea in first‐line cytarabine‐based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT‐AML trial.

Published in:

Journal of Internal Medicine, 2022, v. 292, n. 6, p. 925, doi. 10.1111/joim.13553

By:

Jädersten, Martin;
Lilienthal, Ingrid;
Tsesmetzis, Nikolaos;
Lourda, Magda;
Bengtzén, Sofia;
Bohlin, Anna;
Arnroth, Cornelia;
Erkers, Tom;
Seashore‐Ludlow, Brinton;
Giraud, Géraldine;
Barkhordar, Giti S.;
Tao, Sijia;
Fogelstrand, Linda;
Saft, Leonie;
Östling, Päivi;
Schinazi, Raymond F.;
Kim, Baek;
Schaller, Torsten;
Juliusson, Gunnar;
Deneberg, Stefan

Publication type:

Article

Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention.

Published in:

Advanced Science, 2025, v. 12, n. 3, p. 1, doi. 10.1002/advs.202407572

By:

Youhanna, Sonia;
Kemas, Aurino M.;
Wright, Shane C.;
Zhong, Yi;
Klumpp, Britta;
Klein, Kathrin;
Motso, Aikaterini;
Michel, Maurice;
Ziegler, Nicole;
Shang, Mingmei;
Sabatier, Pierre;
Kannt, Aimo;
Sheng, Hongda;
Oliva‐Vilarnau, Nuria;
Büttner, Florian A.;
Seashore‐Ludlow, Brinton;
Schreiner, Jonas;
Windbergs, Maike;
Cornillet, Martin;
Björkström, Niklas K.

Publication type:

Article

Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth.

Published in:

Cell Death & Disease, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41419-025-07658-1

By:

Treis, Diana;
Lundberg, Kristina Ihrmark;
Bell, Nicola;
Polychronopoulos, Panagiotis Alkinoos;
Tümmler, Conny;
Åkerlund, Emma;
Aliverti, Stefania;
Lilienthal, Ingrid;
Pepich, Adena;
Seashore-Ludlow, Brinton;
Sakaguchi, Kazuyasu;
Kogner, Per;
Johnsen, John Inge;
Wickström, Malin

Publication type:

Article

Enantioselective Synthesis of anti-β-Hydroxy-α-Amido Esters by Asymmetric Transfer Hydrogenation in Emulsions.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 23, p. 7219, doi. 10.1002/chem.201103739

By:

Seashore-Ludlow, Brinton;
Villo, Piret;
Somfai, Peter

Publication type:

Article

Domino Carbopalladation-Carbonylation: Investigation of Substrate Scope.

Published in:

Advanced Synthesis & Catalysis, 2012, v. 354, n. 1, p. 205, doi. 10.1002/adsc.201100678

By:

Seashore-Ludlow, Brinton;
Danielsson, Jakob;
Somfai, Peter

Publication type:

Article

Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.

Published in:

Nucleic Acids Research, 2023, v. 51, n. W1, p. W57, doi. 10.1093/nar/gkad390

By:

Potdar, Swapnil;
Ianevski, Filipp;
Ianevski, Aleksandr;
Tanoli, Ziaurrehman;
Wennerberg, Krister;
Seashore-Ludlow, Brinton;
Kallioniemi, Olli;
Östling, Päivi;
Aittokallio, Tero;
Saarela, Jani

Publication type:

Article

A Portable, Negative-Pressure Actuated, Dynamically Tunable Microfluidic Droplet Generator.

Published in:

Micromachines, 2022, v. 13, n. 11, p. 1823, doi. 10.3390/mi13111823

By:

Trossbach, Martin;
de Lucas Sanz, Marta;
Seashore-Ludlow, Brinton;
Joensson, Haakan N.

Publication type:

Article