Works matching AU Scrutton, Nigel S.

Results: 140

Nanofibrillar Peptide Hydrogels for the Immobilization of Biocatalysts for Chemical Transformations.

Published in:

Macromolecular Rapid Communications, 2014, v. 35, n. 9, p. 868, doi. 10.1002/marc.201400027

By:

Hickling, Christopher;
Toogood, Helen S.;
Saiani, Alberto;
Scrutton, Nigel S.;
Miller, Aline F.

Publication type:

Article

Pinpointing a Mechanistic Switch Between Ketoreduction and 'Ene' Reduction in Short-Chain Dehydrogenases/Reductases.

Published in:

Angewandte Chemie, 2016, v. 128, n. 33, p. 9748, doi. 10.1002/ange.201603785

By:

Lygidakis, Antonios;
Karuppiah, Vijaykumar;
Hoeven, Robin;
Ní Cheallaigh, Aisling;
Leys, David;
Gardiner, John M.;
Toogood, Helen S.;
Scrutton, Nigel S.

Publication type:

Article

Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1532, doi. 10.1002/ange.201409881

By:

Heyes, Derren J.;
Hardman, Samantha J. O.;
Hedison, Tobias M.;
Hoeven, Robin;
Greetham, Greg M.;
Towrie, Michael;
Scrutton, Nigel S.

Publication type:

Article

Protein Motions Are Coupled to the Reaction Chemistry in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase.

Published in:

Angewandte Chemie, 2012, v. 124, n. 37, p. 9440, doi. 10.1002/ange.201202502

By:

Russell, Henry J.;
Jones, Alex R.;
Hay, Sam;
Greetham, Gregory M.;
Towrie, Michael;
Scrutton, Nigel S.

Publication type:

Article

Is There a Dynamic Protein Contribution to the Substrate Trigger in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase?

Published in:

Angewandte Chemie, 2011, v. 123, n. 46, p. 11035, doi. 10.1002/ange.201105132

By:

Jones, Alex R.;
Hardman, Samantha J. O.;
Hay, Sam;
Scrutton, Nigel S.

Publication type:

Article

How Does Pressure Affect Barrier Compression and Isotope Effects in an Enzymatic Hydrogen Tunneling Reaction?

Published in:

Angewandte Chemie, 2011, v. 123, n. 9, p. 2177, doi. 10.1002/ange.201006668

By:

Johannissen, Linus O.;
Scrutton, Nigel S.;
Sutcliffe, Michael J.

Publication type:

Article

Flavin oxidation state impacts on nitrofuran antibiotic binding orientation in nitroreductases.

Published in:

Biochemical Journal, 2021, v. 478, n. 18, p. 3423, doi. 10.1042/BCJ20210489

By:

Toogood, Helen S.;
Scrutton, Nigel S.

Publication type:

Article

A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32816-1

By:

Hernandez-Ortega, Aitor;
Vinaixa, Maria;
Zebec, Ziga;
Takano, Eriko;
Scrutton, Nigel S.

Publication type:

Article

Probing active site geometry using high pressure and secondary isotope effects in an enzyme-catalysed ‘deep’ H-tunnelling reaction.

Published in:

Journal of Physical Organic Chemistry, 2010, v. 23, n. 7, p. 696, doi. 10.1002/poc.1653

By:

Hay, Sam;
Pudney, Christopher R.;
Sutcliffe, Michael J.;
Scrutton, Nigel S.

Publication type:

Article

Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases.

Published in:

ChemCatChem, 2010, v. 2, n. 8, p. 892, doi. 10.1002/cctc.201000094

By:

Toogood, Helen S.;
Gardiner, John M.;
Scrutton, Nigel S.

Publication type:

Article

Co‐production of biofuel, bioplastics and biochemicals during extended fermentation of Halomonas bluephagenesis.

Published in:

Microbial Biotechnology, 2023, v. 16, n. 2, p. 307, doi. 10.1111/1751-7915.14158

By:

Park, Helen;
Toogood, Helen S.;
Chen, Guo‐Qiang;
Scrutton, Nigel S.

Publication type:

Article

Solvent-Slaved Protein Motions Accompany Proton but Not Hydride Tunneling in Light-Activated Protochlorophyllide Oxidoreductase.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 21, p. 3850, doi. 10.1002/anie.200900086

By:

Heyes, Derren J.;
Sakuma, Michiyo;
Scrutton, Nigel S.

Publication type:

Article

Barrier Compression Enhances an Enzymatic Hydrogen-Transfer Reaction.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 8, p. 1452, doi. 10.1002/anie.200805502

By:

Hay, Sam;
Pudney, Christopher R.;
McGrory, Tom A.;
Pang, Jiayun;
Sutcliffe, Michael J.;
Scrutton, Nigel S.

Publication type:

Article

Are Environmentally Coupled Enzymatic Hydrogen Tunneling Reactions Influenced by Changes in Solution Viscosity?

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 3, p. 537, doi. 10.1002/anie.200704484

By:

Hay, Sam;
Pudney, Christopher R.;
Sutcliffe, Michael J.;
Scrutton, Nigel S.

Publication type:

Article

1H, 15N and 13C backbone resonance assignments of pentaerythritol tetranitrate reductase from <italic>Enterobacter cloacae</italic> PB2.

Published in:

Biomolecular NMR Assignments, 2018, v. 12, n. 1, p. 79, doi. 10.1007/s12104-017-9791-2

By:

Iorgu, Andreea I.;
Baxter, Nicola J.;
Cliff, Matthew J.;
Waltho, Jonathan P.;
Hay, Sam;
Scrutton, Nigel S.

Publication type:

Article

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 12, p. 2983, doi. 10.1002/chem.201805219

By:

Issa, Issa S.;
Toogood, Helen S.;
Johannissen, Linus O.;
Raftery, James;
Scrutton, Nigel S.;
Gardiner, John M.

Publication type:

Article

Probing Reversible Chemistry in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase with Kinetic Isotope Effects.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 24, p. 8826, doi. 10.1002/chem.201500958

By:

Jones, Alex R.;
Rentergent, Julius;
Scrutton, Nigel S.;
Hay, Sam

Publication type:

Article

UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis.

Published in:

Nature, 2015, v. 522, n. 7557, p. 502, doi. 10.1038/nature14559

By:

White, Mark D.;
Payne, Karl A. P.;
Fisher, Karl;
Marshall, Stephen A.;
Parker, David;
Rattray, Nicholas J. W.;
Trivedi, Drupad K.;
Goodacre, Royston;
Rigby, Stephen E. J.;
Scrutton, Nigel S.;
Hay, Sam;
Leys, David

Publication type:

Article

New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.

Published in:

Nature, 2015, v. 522, n. 7557, p. 497, doi. 10.1038/nature14560

By:

Payne, Karl A. P.;
White, Mark D.;
Fisher, Karl;
Khara, Basile;
Bailey, Samuel S.;
Parker, David;
Rattray, Nicholas J. W.;
Trivedi, Drupad K.;
Goodacre, Royston;
Beveridge, Rebecca;
Barran, Perdita;
Rigby, Stephen E. J.;
Scrutton, Nigel S.;
Hay, Sam;
Leys, David

Publication type:

Article

Chemoautotrophic production of gaseous hydrocarbons, bioplastics and osmolytes by a novel Halomonas species.

Published in:

Biotechnology for Biofuels & Bioproducts, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13068-023-02404-1

By:

Faulkner, Matthew;
Hoeven, Robin;
Kelly, Paul P.;
Sun, Yaqi;
Park, Helen;
Liu, Lu-Ning;
Toogood, Helen S.;
Scrutton, Nigel S.

Publication type:

Article

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0520-5

By:

Zhang, Shaowei;
Sakuma, Michiyo;
Deora, Girdhar S.;
Levy, Colin W.;
Klausing, Alex;
Breda, Carlo;
Read, Kevin D.;
Edlin, Chris D.;
Ross, Benjamin P.;
Wright Muelas, Marina;
Day, Philip J.;
O'Hagan, Stephen;
Kell, Douglas B.;
Schwarcz, Robert;
Leys, David;
Heyes, Derren J.;
Giorgini, Flaviano;
Scrutton, Nigel S.

Publication type:

Article

Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0242-0

By:

Heyes, Derren J.;
Hardman, Samantha J. O.;
Pedersen, Martin N.;
Woodhouse, Joyce;
De La Mora, Eugenio;
Wulff, Michael;
Weik, Martin;
Cammarata, Marco;
Scrutton, Nigel S.;
Schirò, Giorgio

Publication type:

Article

Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0242-0

By:

Heyes, Derren J.;
Hardman, Samantha J. O.;
Pedersen, Martin N.;
Woodhouse, Joyce;
De La Mora, Eugenio;
Wulff, Michael;
Weik, Martin;
Cammarata, Marco;
Scrutton, Nigel S.;
Schirò, Giorgio

Publication type:

Article

Biosynthesis of cannabigerol and cannabigerolic acid: the gateways to further cannabinoid production.

Published in:

Synthetic Biology (23977000), 2023, v. 8, n. 1, p. 1, doi. 10.1093/synbio/ysad010

By:

Kearsey, Lewis J;
Yan, Cunyu;
Prandi, Nicole;
Toogood, Helen S;
Takano, Eriko;
Scrutton, Nigel S

Publication type:

Article

Promoter engineering for microbial bio-alkane gas production.

Published in:

Synthetic Biology (23977000), 2020, v. 5, n. 1, p. 1, doi. 10.1093/synbio/ysaa022

By:

Trisrivirat, Duangthip;
Hughes, John M X;
Hoeven, Robin;
Faulkner, Matthew;
Toogood, Helen;
Chaiyen, Pimchai;
Scrutton, Nigel S

Publication type:

Article

In silico design and automated learning to boost next-generation smart biomanufacturing.

Published in:

Synthetic Biology (23977000), 2020, v. 5, n. 1, p. 1, doi. 10.1093/synbio/ysaa020

By:

Carbonell, Pablo;
Feuvre, Rosalind Le;
Takano, Eriko;
Scrutton, Nigel S

Publication type:

Article

Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol.

Published in:

Synthetic Biology (23977000), 2020, v. 5, n. 1, p. 1, doi. 10.1093/synbio/ysaa012

By:

Dunstan, Mark S;
Robinson, Christopher J;
Jervis, Adrian J;
Yan, Cunyu;
Carbonell, Pablo;
Hollywood, Katherine A;
Currin, Andrew;
Swainston, Neil;
Feuvre, Rosalind Le;
Micklefield, Jason;
Faulon, Jean-Loup;
Breitling, Rainer;
Turner, Nicholas;
Takano, Eriko;
Scrutton, Nigel S

Publication type:

Article

Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries.

Published in:

Synthetic Biology (23977000), 2019, v. 4, n. 1, p. N.PAG, doi. 10.1093/synbio/ysz025

By:

Currin, Andrew;
Swainston, Neil;
Dunstan, Mark S;
Jervis, Adrian J;
Mulherin, Paul;
Robinson, Christopher J;
Taylor, Sandra;
Carbonell, Pablo;
Hollywood, Katherine A;
Yan, Cunyu;
Takano, Eriko;
Scrutton, Nigel S;
Breitling, Rainer

Publication type:

Article

Design and fabrication of recombinant reflectin-based multilayer reflectors: bio-design engineering and photoisomerism induced wavelength modulation.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94042-6

By:

Wolde-Michael, Emmanuel;
Roberts, Aled D.;
Heyes, Derren J.;
Dumanli, Ahu G.;
Blaker, Jonny J.;
Takano, Eriko;
Scrutton, Nigel S.

Publication type:

Article

α/β Barrel evolution and the modular assembly of enzymes: Emerging trends in the flavin oxidase/dehydrogenase family.

Published in:

BioEssays, 1994, v. 16, n. 2, p. 115, doi. 10.1002/bies.950160208

By:

Scrutton, Nigel S.

Publication type:

Article

New enzymes for old: Redesigning the coenzyme and substrate specificities of glutathione reductase.

Published in:

BioEssays, 1991, v. 13, n. 10, p. 515, doi. 10.1002/bies.950131005

By:

Perham, Richard N.;
Scrutton, Nigel S.;
Berry, Alan

Publication type:

Article

Ultrafast Red Light Activation of Synechocystis Phytochrome Cph1 Triggers Major Structural Change to Form the Pfr Signalling-Competent State.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052418

By:

Heyes, Derren J.;
Khara, Basile;
Sakuma, Michiyo;
Hardman, Samantha J. O.;
O'Cualain, Ronan;
Rigby, Stephen E. J.;
Scrutton, Nigel S.

Publication type:

Article

Mechanistic Reappraisal of Early Stage Photochemistry in the Light-Driven Enzyme Protochlorophyllide Oxidoreductase.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045642

By:

Heyes, Derren J.;
Hardman, Samantha J. O.;
Mansell, David;
Gardiner, John M.;
Scrutton, Nigel S.;
Subramanyam, Rajagopal

Publication type:

Article

Human Cryptochrome-1 Confers Light Independent Biological Activity in Transgenic Drosophila Correlated with Flavin Radical Stability.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0031867

By:

Vieira, Jacqueline;
Jones, Alex R.;
Danon, Antoine;
Sakuma, Michiyo;
Hoang, Nathalie;
Robles, David;
Tait, Shirley;
Heyes, Derren J.;
Picot, Marie;
Yoshii, Taishi;
Helfrich-Förster, Charlotte;
Soubigou, Guillaume;
Coppee, Jean-Yves;
Klarsfeld, André;
Rouyer, Francois;
Scrutton, Nigel S.;
Ahmad, Margaret

Publication type:

Article

Engineering nature for gaseous hydrocarbon production.

Published in:

2020

By:

Amer, Mohamed;
Toogood, Helen;
Scrutton, Nigel S.

Publication type:

Literature Review

Arabinose as an overlooked sugar for microbial bioproduction of chemical building blocks.

Published in:

Critical Reviews in Biotechnology, 2024, v. 44, n. 6, p. 1103, doi. 10.1080/07388551.2023.2270702

By:

Kumar, Vinod;
Agrawal, Deepti;
Bommareddy, Rajesh Reddy;
Islam, M. Ahsanul;
Jacob, Samuel;
Balan, Venkatesh;
Singh, Vijai;
Thakur, Vijay Kumar;
Navani, Naveen Kumar;
Scrutton, Nigel S.

Publication type:

Article

Quantum Mechanics/Molecular Mechanics Studies on the Mechanism of Action of Cofactor Pyridoxal 5′-Phosphate in Ornithine 4,5-Aminomutase.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 36, p. 11390, doi. 10.1002/chem.201402759

By:

Pang, Jiayun;
Scrutton, Nigel S.;
Sutcliffe, Michael J.

Publication type:

Article

A microbial platform for renewable propane synthesis based on a fermentative butanol pathway.

Published in:

Biotechnology for Biofuels, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13068-015-0231-1

By:

Menon, Navya;
Pásztor, András;
Menon, Binuraj R. K.;
Kallio, Pauli;
Fisher, Karl;
Akhtar, M. Kalim;
Leys, David;
Jones, Patrik R.;
Scrutton, Nigel S.

Publication type:

Article

Magnetic Fields Modulate Blue-Light-Dependent Regulation of Neuronal Firing by Cryptochrome.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 42, p. 10742, doi. 10.1523/JNEUROSCI.2140-16.2016

By:

Giachello, Carlo N. G.;
Scrutton, Nigel S.;
Jones, Alex R.;
Baines, Richard A.

Publication type:

Article

Vertebrate Cryptochromes are Vestigial Flavoproteins.

Published in:

Scientific Reports, 2017, p. 44906, doi. 10.1038/srep44906

By:

Kutta, Roger J.;
Archipowa, Nataliya;
Johannissen, Linus O.;
Jones, Alex R.;
Scrutton, Nigel S.

Publication type:

Article

High‐Titer Bio‐Styrene Production Afforded by Whole‐Cell Cascade Biotransformation.

Published in:

ChemCatChem, 2023, v. 15, n. 5, p. 1, doi. 10.1002/cctc.202201102

By:

Messiha, Hanan L.;
Scrutton, Nigel S.;
Leys, David

Publication type:

Article

Alternative Hydride Sources for Ene-Reductases: Current Trends.

Published in:

ChemCatChem, 2014, v. 6, n. 4, p. 951, doi. 10.1002/cctc.201300911

By:

Toogood, Helen S.;
Knaus, Tanja;
Scrutton, Nigel S.

Publication type:

Article

biochem4j: Integrated and extensible biochemical knowledge through graph databases.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0179130

By:

Swainston, Neil;
Batista-Navarro, Riza;
Carbonell, Pablo;
Dobson, Paul D.;
Dunstan, Mark;
Jervis, Adrian J.;
Vinaixa, Maria;
Williams, Alan R.;
Ananiadou, Sophia;
Faulon, Jean-Loup;
Mendes, Pedro;
Kell, Douglas B.;
Scrutton, Nigel S.;
Breitling, Rainer

Publication type:

Article

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase

Published in:

FEBS Letters, 2005, v. 579, n. 25, p. 5582, doi. 10.1016/j.febslet.2005.09.023

By:

Neeli, Rajasekhar;
Girvan, Hazel M.;
Lawrence, Andrew;
Warren, Martin J.;
Leys, David;
Scrutton, Nigel S.;
Munro, Andrew W.

Publication type:

Article

SignatureFinder enables sequence mining to identify cobalamin‐dependent photoreceptor proteins.

Published in:

FEBS Journal, 2025, v. 292, n. 3, p. 635, doi. 10.1111/febs.17377

By:

Yu, Yuqi;
Jeffreys, Laura N.;
Poddar, Harshwardhan;
Hill, Adam;
Johannissen, Linus;
Dai, Fanzhuo;
Sakuma, Michiyo;
Leys, David;
Heyes, Derren J.;
Zhang, Shaowei;
Scrutton, Nigel S.

Publication type:

Article

Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.

Published in:

FEBS Journal, 2024, v. 291, n. 7, p. 1404, doi. 10.1111/febs.17025

By:

Taylor, Aoife;
Zhang, Shaowei;
Johannissen, Linus O.;
Sakuma, Michiyo;
Phillips, Robert S.;
Green, Anthony P.;
Hay, Sam;
Heyes, Derren J.;
Scrutton, Nigel S.

Publication type:

Article

Unravelling the complexity of enzyme catalysis.

Published in:

FEBS Journal, 2023, v. 290, n. 9, p. 2204, doi. 10.1111/febs.16796

By:

Scrutton, Nigel S.

Publication type:

Article

A guide to time‐resolved structural analysis of light‐activated proteins.

Published in:

FEBS Journal, 2022, v. 289, n. 3, p. 576, doi. 10.1111/febs.15880

By:

Poddar, Harshwardhan;
Heyes, Derren J.;
Schirò, Giorgio;
Weik, Martin;
Leys, David;
Scrutton, Nigel S.

Publication type:

Article

Insights into the H2O2‐driven catalytic mechanism of fungal lytic polysaccharide monooxygenases.

Published in:

FEBS Journal, 2021, v. 288, n. 13, p. 4115, doi. 10.1111/febs.15704

By:

Hedison, Tobias M.;
Breslmayr, Erik;
Shanmugam, Muralidharan;
Karnpakdee, Kwankao;
Heyes, Derren J.;
Green, Anthony P.;
Ludwig, Roland;
Scrutton, Nigel S.;
Kracher, Daniel

Publication type:

Article

In conversation with Nigel Scrutton.

Published in:

FEBS Journal, 2021, v. 288, n. 6, p. 1728, doi. 10.1111/febs.15632

By:

Dhillon, Paraminder;
Scrutton, Nigel S.

Publication type:

Article